| Trial ID: | L0676 |
| Source ID: | ISRCTN81956288
|
| Associated Drug: |
Polyunsaturated Fatty Acids
|
| Title: |
The effect of n-3 polyunsaturated fatty acid (PUFA) supplementation in patients with steatosis due to non-alcoholic fatty liver disease
|
| Acronym: |
--
|
| Status: |
Not Recruiting
|
| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Topic: Metabolic and Endocrine; Subtopic: Metabolic and Endocrine (all Subtopics); Disease: Metabolic & Endocrine (not diabetes) <br>Digestive System <br>Non-alcoholic fatty liver disease
|
| Interventions: |
58 patients with biopsy proven steatosis due to non-alcoholic fatty liver disease (NAFLD) will be randomised to 3.5 g n-3 polyunsaturated fatty acid (PUFA) or oleic enriched sunflower oil capsules for 3 months. <br><br>Follow-up length: 3 months<br>Study
|
| Outcome Measures: |
Hepatic steatosis as determined by magnetic resonance imaging (MRI) spectroscopy pre- and post-intervention<br>Liver fat stores (MR spectroscopy), measured pre- and post-interventionMeasured pre- and post-intervention:<br>1. Liver biochemistry<br>2. Lipid profile<br>3. Insulin resistance<br>4. Blood pressure<br>5. Abdominal visceral fat<br>6. Inflammatory cytokine profile
|
| Sponsor/Collaborators: |
University of Nottingham (UK)
|
| Gender: |
All
|
| Age: |
nannan
|
| Phases: |
Not applicable
|
| Enrollment: |
58
|
| Study Type: |
Interventional
|
| Study Designs: |
Single centre randomised interventional treatment trial (Treatment)
|
| Start Date: |
19/05/2010
|
| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
17 October 2016
|
| Locations: |
United Kingdom
|
| URL: |
http://isrctn.com/ISRCTN81956288
|
