| Trial ID: | L0777 |
| Source ID: | IRCT20181005041238N1
|
| Associated Drug: |
Zinc
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| Title: |
Effect of Zinc Supplementation and dietary weight loss on oxidative stress, steatosis, liver enzymes, glycemic and lipid profile Status in Non-Alcoholic Fatty Liver disease
|
| Acronym: |
--
|
| Status: |
Recruiting
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| Study Results: |
No Results Available
|
| Results: |
--
|
| Conditions: |
Nonalcoholic fatty liver.
|
| Interventions: |
Intervention 1: Intervention group: weight loss diet and zinc gluconate(30 mg elemental-Dine) for 3 months in non-alcoholic fatty liver disease. Intervention 2: Control group: weight loss diet and placebo (Dine) for 3 months in non-alcoholic fatty liver d
|
| Outcome Measures: |
Differences of serum AST enzyme. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum ALP. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum SOD1 enzyme. Timepoint: Before the intervention begins and Week 12. Method of measurement: colorimetry.;Differences of serum MDA. Timepoint: Before the intervention begins and Week 12. Method of measurement: colorimetry.;Differences of serum insulin. Timepoint: Before the intervention begins and week12. Method of measurement: kit.;Differences of fasting blood sugar. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum triglyceride. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum LDL-C. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum HDL-C. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum total cholesterol. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.;Differences of serum ALT enzyme. Timepoint: Before the intervention begins and Week 12. Method of measurement: kit.Differences of BMI. Timepoint: Before the intervention begins and week6 and week12. Method of measurement: Weighing scales and meter.;Differences of body fat percentage. Timepoint: Before the intervention begins and week6 and week12. Method of measurement: body stat.;Differences of waist circumference. Timepoint: Before the intervention begins and week6 and week12. Method of measurement: meter.;Differences of Hip circumference. Timepoint: Before the intervention begins and week6 and week12. Method of measurement: meter.
|
| Sponsor/Collaborators: |
Esfahan University of Medical Sciences
|
| Gender: |
All
|
| Age: |
18 yearsno limit
|
| Phases: |
Phase 0
|
| Enrollment: |
60
|
| Study Type: |
interventional
|
| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Samples were randomly assigned to coding 1 and 2, respectively, into two groups of control and intervention, Blinding
|
| Start Date: |
13/12/2018
|
| Completion Date: |
--
|
| Results First Posted: |
--
|
| Last Update Posted: |
14 January 2019
|
| Locations: |
Iran (Islamic Republic of)
|
| URL: |
http://en.irct.ir/trial/34297
|
