Pre-defined epitopes

Currently, SAS provides pre-defined epitopes including both validated and predicted epitope regions. The detailed information of each is provided in the below table:

Pre-defined epitopes	Epitope position	Reference
spike_validated_epi_1	372,375,376,378,403,404,405,408,437,439,440,449,496,498,499,500,501,502,503,504,505,506,508	2DD8,3BGF [8-9]
spike_validated_epi_2	446,449,484,485,486,489,490,492,493,494,496,498,501,505	7BYR [10]
spike_validated_epi_3	403,405,409,415,416,417,420,421,453,455,456,457,458,460,473,475,476,477,486,487,489,490,493,495,496,498,500,501,502,505	7BZ5 [11]
spike_validated_epi_4	403,405,408,415,416,417,421,453,455,456,457,458,459,460,473,474,475,476,477,486,487,489,498,500,501,502,504,505	6XCM [12]
spike_validated_epi_5	369,370,371,372,374,376,377,378,379,380,381,382,383,384,385,386,390,392,428,429,430,515,516,517,518,519	6W41,6YLA,6YM0 [13]
spike_validated_epi_6	334,335,337,339,340,343,344,345,346,354,356,357,359,360,361,441,509	6WPS,6WPT [14]
spike_validated_epi_7	403,405,406,408,409,415,416,417,420,421,455,456,457,458,460,473,474,475,476,477,486,487,489,493,495,502,504,505	7C01 [15]
spike_validated_epi_8	449,453,455,456,483,484,485,486,487,489,490,492,493,494	6XEY [16]
spike_validated_epi_9	346,444,446,447,448,449,450,452,483,484,485,490,494	7BWJ [17]
spike_validated_epi_10	417,453,455,456,484,485,486,487,488,489,493	6XDG [18]
spike_validated_epi_11	369,374,375,376,377,378,379,380,381,382,383,384,385,386,388,389,390,392,411,412,413,414,427,428,429,430,517	6ZER,6ZCZ,6ZFO,6ZDH,6ZDG [19]
spike_validated_epi_12	369,372,373,374,375,376,377,378,379,380,385,405,407,408,411,412,503,504	7CAH [20]
spike_validated_epi_13	446,449,456,475,483,484,485,486,487,489,493	7JMP [21]
spike_validated_epi_14	144,145,146,147,150,152,245,246,247,248,249	7C2L [22]
spike_validated_epi_15	444,446,447,449,450,452,470,478,479,481,482,483,484,485,490	7CHH
spike_predicted_epi_1	30,32,33,34,56,57,58,59,60,61,63,191,217,218,219,266,267,293	SEPPA3.0 [3]
spike_predicted_epi_2	38,39,40,41,42,43,44,45,49,51,52,53,204,206,220,221,222,224,225,278,279,280,282,283,284,285,286,287,288	SEPPA3.0 [3]
spike_predicted_epi_3	50,273,274,291,298,301,302,303,304,305	SEPPA3.0 [3]
spike_predicted_epi_4	65,80,81,82,83,84,85,86,104,108,110,199,231,233,234,235,236,237,238,239,269	SEPPA3.0 [3]
spike_predicted_epi_5	109,111,112,113,114,115,116,132,133,134,135,136,137,139	SEPPA3.0 [3]
spike_predicted_epi_6	327,328,329,388,389,528,529,530,531,532,533,534,542,544,545,546,547,578,579,580	SEPPA3.0 [3]
spike_predicted_epi_7	341,342,344,345,346,347,348,349,350,351,399,401,402,436,442,448,450,451,454,509	SEPPA3.0 [3]
spike_predicted_epi_8	600,601,603,604,605,663,673,674,675,676,689,690,691,692	SEPPA3.0 [3]
spike_predicted_epi_9	654,655,656,657,658,660,671,693,695,696	SEPPA3.0 [3]
spike_predicted_epi_10	659,661,662,669,697,698,699,700,701,702	SEPPA3.0 [3]
spike_predicted_epi_11	723,724,725,726,938,1028,1041,1042,1043,1044,1045,1047,1048,1068	SEPPA3.0 [3]
spike_predicted_epi_12	727,728,729,730,731,777,778,782,944,945,946,947,948,949,951,1017,1018,1019,1020,1021,1022,1023,1024,1026,1027,1056,1057,1058,1059	SEPPA3.0 [3]
spike_predicted_epi_13	884,885,886,887,888,889,890,891,892,893,894,895,1035	SEPPA3.0 [3]