Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
lipogenesis1889 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19454 | 26560698 | J Exp Clin Cancer Res | Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice. | 2015 | Details |
| A19474 | 26539118 | Front Pharmacol | Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG2 cells. | 2015 | Details |
| A19495 | 26523205 | World J Hepatol | Dietary approach in the treatment of nonalcoholic fatty liver disease. | 2015 | Details |
| A19504 | 26517927 | Biochem Soc Trans | Tribbles-1: a novel regulator of hepatic lipid metabolism in humans. | 2015 | Details |
| A19589 | 26471014 | Food Funct | Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. | 2016 | Details |
| A19598 | 26463593 | Genes Nutr | Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. | 2015 | Details |
| A19601 | 26462866 | Diabetes Obes Metab | Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis. | 2015 | Details |
| A19604 | 26461414 | Free Radic Biol Med | Oxysterols in the orchestra of liver cell metabolism. | 2014 | Details |
| A19673 | 26420354 | Eur J Pharmacol | Deficiency in apolipoprotein A-I ablates the pharmacological effects of metformin on plasma glucose homeostasis and hepatic lipid deposition. | 2015 | Details |
| A19683 | 26414963 | J Clin Endocrinol Metab | Sex-Specific Differences in Hepatic Fat Oxidation and Synthesis May Explain the Higher Propensity for NAFLD in Men. | 2015 | Details |
| A19687 | 26409295 | Metabolism | Genetics of nonalcoholic fatty liver disease. | 2015 | Details |
| A19711 | 26399788 | FASEB J | GPR119: a promising target for nonalcoholic fatty liver disease. | 2015 | Details |
| A19724 | 26394261 | Appl Physiol Nutr Metab | Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats. | 2015 | Details |
| A19726 | 26394162 | J Hepatol | CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy. | 2015 | Details |
| A19727 | 26394161 | J Hepatol | Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis. | 2015 | Details |
| A19769 | 26363221 | Mol Cell Endocrinol | AMPK-dependent modulation of hepatic lipid metabolism by nesfatin-1. | 2015 | Details |
| A19838 | 26315841 | Int J Obes (Lond) | Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. | 2015 | Details |
| A19862 | 26299811 | Toxicology | Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases. | 2015 | Details |
| A19872 | 26292849 | Br J Pharmacol | Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes. | 2015 | Details |
| A19876 | 26290284 | Front Med | Molecular mechanisms of fatty liver in obesity. | 2015 | Details |
| A19888 | 26282675 | Gut | MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway. | 2015 | Details |
| A19909 | 26273591 | Biomed Res Int | Drug Induced Steatohepatitis: An Uncommon Culprit of a Common Disease. | 2015 | Details |
| A19910 | 26272872 | J Hepatol | Upregulation of miR-125b by estrogen protects against non-alcoholic fatty liver in female mice. | 2015 | Details |
| A19922 | 26264689 | Proc Nutr Soc | Dietary carbohydrate and control of hepatic gene expression: mechanistic links from ATP and phosphate ester homeostasis to the carbohydrate-response element-binding protein. | 2015 | Details |
| A19927 | 26260846 | Biochim Biophys Acta | 14-3-3β and γ differentially regulate peroxisome proliferator activated receptor γ2 transactivation and hepatic lipid metabolism. | 2015 | Details |
| A19930 | 26258810 | Eur J Cancer Prev | Pentoxifylline prevents nonalcoholic steatohepatitis-related liver pre-neoplasms by inhibiting hepatic inflammation and lipogenesis. | 2016 | Details |
| A19943 | 26251667 | Nutr Metab (Lond) | Exercise training improves liver steatosis in mice. | 2015 | Details |
| A19955 | 26242257 | Curr Med Chem | Flavonoids and Related Compounds in Non-Alcoholic Fatty Liver Disease Therapy. | 2015 | Details |
| A19996 | 26215699 | J Pharmacol Sci | JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis. | 2015 | Details |
| A20015 | 26203597 | Curr Opin Clin Nutr Metab Care | Fructose and liver function--is this behind nonalcoholic liver disease? | 2015 | Details |
| A20034 | 26198708 | Wiley Interdiscip Rev RNA | 'Micro-managers' of hepatic lipid metabolism and NAFLD. | 2015 | Details |
| A20053 | 26190035 | Hepatol Res | Amelioration of free fatty acid-induced fatty liver by quercetin-3-O-β-D-glucuronide through modulation of peroxisome proliferator-activated receptor-alpha/sterol regulatory element-binding protein-1c signaling. | 2015 | Details |
| A20071 | 26176317 | J Agric Food Chem | Fermented Rhus verniciflua Stokes Extract Exerts an Antihepatic Lipogenic Effect in Oleic-Acid-Induced HepG2 Cells via Upregulation of AMP-Activated Protein Kinase. | 2015 | Details |
| A20092 | 26160474 | Clin Res Hepatol Gastroenterol | Novel therapeutic targets for steatohepatitis. | 2015 | Details |
| A20107 | 26151056 | Hepatobiliary Surg Nutr | Carotenoids and non-alcoholic fatty liver disease. | 2015 | Details |
| A20115 | 26147081 | Nature | The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. | 2015 | Details |
| A20171 | 26113297 | Am J Physiol Gastrointest Liver Physiol | Hepatic TLR4 signaling in obese NAFLD. | 2015 | Details |
| A20180 | 26103964 | BMC Gastroenterol | Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis. | 2015 | Details |
| A20186 | 26098879 | PLoS One | Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet. | 2015 | Details |
| A20195 | 26090419 | Biomed Res Int | Individual CLA Isomers, c9t11 and t10c12, Prevent Excess Liver Glycogen Storage and Inhibit Lipogenic Genes Expression Induced by High-Fructose Diet in Rats. | 2015 | Details |
| A20225 | 26078098 | J Physiol Biochem | FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice. | 2015 | Details |
| A20268 | 26052390 | World J Hepatol | Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease. | 2015 | Details |
| A20292 | 26042770 | PLoS One | mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). | 2015 | Details |
| A20308 | 26036873 | Electrophoresis | Comparative proteomic analysis using 2DE-LC-MS/MS reveals the mechanism of Fuzhuan brick tea extract against hepatic fat accumulation in rats with nonalcoholic fatty liver disease. | 2015 | Details |
| A20311 | 26035386 | Dis Model Mech | Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice. | 2015 | Details |
| A20313 | 26033743 | J Nutr Biochem | Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20360 | 26017330 | Mol Med Rep | Lycium ruthenicum extract alleviates high-fat diet-induced nonalcoholic fatty liver disease via enhancing the AMPK signaling pathway. | 2015 | Details |
| A20364 | 26015548 | Diabetes | Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice. | 2015 | Details |
| A20372 | 26005677 | Hepatobiliary Surg Nutr | Carbohydrate intake and nonalcoholic fatty liver disease: fructose as a weapon of mass destruction. | 2015 | Details |
| A20383 | 26000287 | Biomed Res Int | Inhibitory effects of eucalyptus and banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats. | 2015 | Details |
| A20389 | 25998209 | Hepatology | Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice. | 2015 | Details |
| A20397 | 25993337 | PLoS One | Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. | 2015 | Details |
| A20400 | 25992705 | Proc Nutr Soc | Relevance of liver fat to the impact of dietary extrinsic sugars on lipid metabolism. | 2015 | Details |
| A20424 | 25974403 | Endocrinology | 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes. | 2015 | Details |
| A20435 | 25967664 | Am J Chin Med | The Hexane Fraction of cyperus rotundus Prevents Non-Alcoholic Fatty Liver Disease Through the Inhibition of Liver X Receptor α-Mediated Activation of Sterol Regulatory Element Binding Protein-1c. | 2015 | Details |
| A20491 | 25925967 | Phytomedicine | [6]-gingerol dampens hepatic steatosis and inflammation in experimental nonalcoholic steatohepatitis. | 2015 | Details |
| A20510 | 25915743 | Nutr Diabetes | Effect of multiple binge alcohol on diet-induced liver injury in a mouse model of obesity. | 2015 | Details |
| A20535 | 25905791 | Food Funct | Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose. | 2015 | Details |
| A20547 | 25894944 | Curr Diab Rep | Nonalcoholic fatty liver disease and type 2 diabetes: common pathophysiologic mechanisms. | 2015 | Details |
| A20555 | 25890430 | Obes Res Clin Pract | Soy β-conglycinin improves obesity-induced metabolic abnormalities in a rat model of nonalcoholic fatty liver disease. | 2014 | Details |
| A20616 | 25849950 | Nutrients | Hepatoprotective effect of herb formula KIOM2012H against nonalcoholic fatty liver disease. | 2015 | Details |
| A20643 | 25837920 | J Pharmacol Sci | Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats. | 2014 | Details |
| A20655 | 25827944 | J Physiol Biochem | Liver delipidating effect of a combination of resveratrol and quercetin in rats fed an obesogenic diet. | 2015 | Details |
| A20678 | 25808650 | Curr Drug Targets | The link between Hepatic Vitamin A Metabolism and Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20701 | 25789613 | PLoS One | Gp78, an E3 ubiquitin ligase acts as a gatekeeper suppressing nonalcoholic steatohepatitis (NASH) and liver cancer. | 2015 | Details |
| A20743 | 25763607 | J Clin Endocrinol Metab | Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant. | 2015 | Details |
| A20763 | 25748419 | Life Sci | Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice. | 2015 | Details |
| A20767 | 25745505 | Nutr Metab (Lond) | The flavonoid, naringenin, decreases adipose tissue mass and attenuates ovariectomy-associated metabolic disturbances in mice. | 2015 | Details |
| A20775 | 25742316 | Biochem J | Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity. | 2015 | Details |
| A20779 | 25740151 | Biol Rev Camb Philos Soc | De novo lipogenesis in the liver in health and disease: more than just a shunting yard for glucose. | 2015 | Details |
| A20788 | 25733650 | Am J Clin Nutr | High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. | 2015 | Details |
| A20818 | 25714671 | Am J Physiol Endocrinol Metab | Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology. | 2015 | Details |
| A20832 | 25706109 | Curr Drug Targets | Discovery of Novel Anti-Diabetic Drugs by Targeting Lipid Metabolism. | 2015 | Details |
| A20838 | 25701781 | Biochem Biophys Res Commun | Protective effects of aerobic swimming training on high-fat diet induced nonalcoholic fatty liver disease: regulation of lipid metabolism via PANDER-AKT pathway. | 2015 | Details |
| A20874 | 25671834 | Ann Hepatol | Granulocyte-colony stimulating factor prevents the development of hepatic steatosis in rats. | 2015 | Details |
| A20876 | 25671200 | J Exerc Nutrition Biochem | Effect of aerobic exercise training on non-alcoholic fatty liver disease induced by a high fat diet in C57BL/6 mice. | 2014 | Details |
| A20916 | 25646773 | PLoS One | Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt. | 2015 | Details |
| A20928 | 25634759 | Cell Physiol Biochem | Human sterol regulatory element-binding protein 1a contributes significantly to hepatic lipogenic gene expression. | 2015 | Details |
| A20938 | 25631376 | IUBMB Life | Modulation of hepatic lipid metabolism by olive oil and its phenols in nonalcoholic fatty liver disease. | 2015 | Details |
| A20959 | 25617503 | J Hepatol | Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity. | 2015 | Details |
| A20980 | 25605057 | Int J Mol Med | Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. | 2015 | Details |
| A21110 | 25533124 | Biochim Biophys Acta | Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα. | 2014 | Details |
| A21125 | 25527748 | Am J Clin Nutr | Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis. | 2014 | Details |
| A21128 | 25526027 | Oncotarget | Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat. | 2014 | Details |
| A21158 | 25514388 | Nutrients | The role of dietary sugars and de novo lipogenesis in non-alcoholic fatty liver disease. | 2014 | Details |
| A21174 | 25500885 | J Clin Invest | Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease. | 2014 | Details |
| A21216 | 25474087 | Int J Mol Sci | Altered fatty acid metabolism-related gene expression in liver from morbidly obese women with non-alcoholic fatty liver disease. | 2014 | Details |
| A21264 | 25450203 | J Hepatol | Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease. | 2014 | Details |
| A21321 | 25406988 | Lipids Health Dis | Inhibiting CB1 receptors improves lipogenesis in an in vitro non-alcoholic fatty liver disease model. | 2014 | Details |
| A21323 | 25405502 | J Clin Endocrinol Metab | Liver fat content and hepatic insulin sensitivity in overweight patients with type 1 diabetes. | 2014 | Details |
| A21329 | 25401691 | Nat Med | The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. | 2014 | Details |
| A21352 | 25382334 | Chin Med J (Engl) | Expression and significance of fat mass and obesity associated gene and forkhead transcription factor O1 in non-alcoholic fatty liver disease. | 2014 | Details |
| A21361 | 25376397 | Obesity (Silver Spring) | The role of small heterodimer partner in nonalcoholic fatty liver disease improvement after sleeve gastrectomy in mice. | 2014 | Details |
| A21403 | 25347470 | J Clin Invest | Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia. | 2014 | Details |
| A21426 | 25328157 | Br J Nutr | Astaxanthin lowers plasma TAG concentrations and increases hepatic antioxidant gene expression in diet-induced obesity mice. | 2014 | Details |
| A21438 | 25317840 | Food Funct | Lactobacillus plantarum NCU116 improves liver function, oxidative stress and lipid metabolism in rats with high fat diet induced non-alcoholic fatty liver disease. | 2014 | Details |
| A21451 | 25310357 | Mol Med Rep | Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice. | 2014 | Details |
| A21457 | 25307311 | Mini Rev Med Chem | Long chain omega-3 polyunsaturated fatty acids in pediatric metabolic syndrome. | 2014 | Details |
| A21500 | 25271296 | J Lipid Res | A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice. | 2014 | Details |
| A21514 | 25261688 | J Ethnopharmacol | Magnolia officinalis attenuates free fatty acid-induced lipogenesis via AMPK phosphorylation in hepatocytes. | 2014 | Details |