Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09014 | 31904420 | Biochim Biophys Acta Mol Cell Biol Lipids | Carotenoids and fatty liver disease: Current knowledge and research gaps. | 2020 | Details |
| A09033 | 31897838 | Eur J Pediatr | Causes of secondary non-alcoholic fatty liver disease in non-obese children below 10 years. | 2020 | Details |
| A09038 | 31894315 | Int J Mol Med | miR‑146a improves hepatic lipid and glucose metabolism by targeting MED1. | 2019 | Details |
| A09040 | 31893310 | Cell Mol Life Sci | Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism. | 2019 | Details |
| A09044 | 31891606 | PLoS One | Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A09046 | 31889755 | J Clin Exp Hepatol | Peroxisome Proliferator-Activated Receptors and Their Agonists in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09050 | 31889412 | IUBMB Life | Inhibiting miR-27a and miR-142-5p attenuate nonalcoholic fatty liver disease by regulating Nrf2 signaling pathway. | 2019 | Details |
| A09054 | 31888190 | Nutrients | Nonalcoholic Fatty Liver Disease Induced by High-Fat Diet in C57bl/6 Models. | 2019 | Details |
| A09057 | 34350368 | Cardiol Plus | Bile Acid and Cholesterol Metabolism in Atherosclerotic Cardiovascular Disease and Therapy. | 2020 | Details |
| A09066 | 31885789 | Oxid Med Cell Longev | Green Tea Prevents NAFLD by Modulation of miR-34a and miR-194 Expression in a High-Fat Diet Mouse Model. | 2019 | Details |
| A09076 | 31883408 | Liver Int | Farnesoid X receptor activation induces the degradation of hepatotoxic 1-deoxysphingolipids in non-alcoholic fatty liver disease. | 2020 | Details |
| A09078 | 31882889 | Sci Rep | Hepatic Mitochondrial Oxidative Metabolism and Lipogenesis Synergistically Adapt to Mediate Healthy Embryonic-to-Neonatal Transition in Chicken. | 2019 | Details |
| A09096 | 31877771 | Cells | Anti-NASH Drug Development Hitches a Lift on PPAR Agonism. | 2019 | Details |
| A09098 | 31877412 | Mol Ther Nucleic Acids | Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. | 2019 | Details |
| A09109 | 31870746 | Ann Hepatol | Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis. | 2019 | Details |
| A09128 | 31865143 | Biomed Pharmacother | Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. | 2019 | Details |
| A09136 | 31861818 | Cells | Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis. | 2019 | Details |
| A09137 | 31861664 | Int J Mol Sci | Sphingolipids in Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma: Ceramide Turnover. | 2019 | Details |
| A09151 | 31857195 | J Hepatol | ARRB1 inhibits non-alcoholic steatohepatitis progression by promoting GDF15 maturation. | 2019 | Details |
| A09163 | 31852298 | Artif Cells Nanomed Biotechnol | Osteopontin acts as a negative regulator of autophagy accelerating lipid accumulation during the development of nonalcoholic fatty liver disease. | 2020 | Details |
| A09178 | 31847157 | Nutrients | Sarcopoterium spinosum Inhibited the Development of Non-Alcoholic Steatosis and Steatohepatitis in Mice. | 2019 | Details |
| A09179 | 31846961 | Lifestyle Genom | One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics. | 2019 | Details |
| A09189 | 31842467 | Int J Mol Sci | Resveratrol Treatment Enhances the Cellular Response to Leptin by Increasing OBRb Content in Palmitate-Induced Steatotic HepG2 Cells. | 2019 | Details |
| A09191 | 31841118 | Aging (Albany NY) | Effects of XIAP on high fat diet-induced hepatic steatosis: a mechanism involving NLRP3 inflammasome and oxidative stress. | 2019 | Details |
| A09195 | 31840358 | Hepatol Res | Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives. | 2020 | Details |
| A09206 | 31836013 | BMC Complement Altern Med | Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice. | 2019 | Details |
| A09210 | 31835339 | Metabolites | Acupuncture on ST36, CV4 and KI1 Suppresses the Progression of Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2019 | Details |
| A09212 | 31834842 | J Med Food | Effects of Eriobotrya japonica Water Extract on Alcoholic and Nonalcoholic Fatty Liver Impairment. | 2019 | Details |
| A09213 | 31834465 | Naunyn Schmiedebergs Arch Pharmacol | NLRP3 inhibitor glibenclamide attenuates high-fat diet and streptozotocin-induced non-alcoholic fatty liver disease in rat: studies on oxidative stress, inflammation, DNA damage and insulin signalling pathway. | 2019 | Details |
| A09216 | 31833787 | Epigenomics | Rat liver epigenome programing by perinatal exposure to 2,2',4'4'-tetrabromodiphenyl ether. | 2019 | Details |
| A09222 | 31832001 | World J Gastroenterol | LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway. | 2019 | Details |
| A09223 | 31831718 | Aging (Albany NY) | Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. | 2019 | Details |
| A09224 | 31831621 | J Biol Chem | Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis. | 2019 | Details |
| A09232 | 31826069 | J Gastrointestin Liver Dis | PNPLA3 I148M Polymorphism in Patients with Nonalcoholic Fatty Liver Disease, Obesity and Prediabetes. | 2019 | Details |
| A09242 | 31821039 | Am J Physiol Endocrinol Metab | Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism. | 2019 | Details |
| A09247 | 31819375 | Drug Des Devel Ther | Liraglutide Improves Non-Alcoholic Fatty Liver Disease In Diabetic Mice By Modulating Inflammatory Signaling Pathways. | 2019 | Details |
| A09255 | 31816412 | Biochim Biophys Acta Mol Cell Biol Lipids | Aquaporin-9 is involved in the lipid-lowering activity of the nutraceutical silybin on hepatocytes through modulation of autophagy and lipid droplets composition. | 2019 | Details |
| A09256 | 31816064 | Hum Mol Genet | Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia. | 2020 | Details |
| A09259 | 31814783 | Hepat Med | A Review Of Current And Upcoming Treatment Modalities In Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A09275 | 31809000 | J Cell Mol Med | Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. | 2019 | Details |
| A09280 | 31808097 | Environ Sci Pollut Res Int | Could phthalates exposure contribute to the development of metabolic syndrome and liver disease in humans? | 2019 | Details |
| A09284 | 31805951 | Lipids Health Dis | Target genes associated with lipid and glucose metabolism in non-alcoholic fatty liver disease. | 2019 | Details |
| A09287 | 31805072 | PLoS One | Hyperglycemia induces key genetic and phenotypic changes in human liver epithelial HepG2 cells which parallel the Leprdb/J mouse model of non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A09291 | 31803887 | Food Funct | The regulatory effects of phytosterol esters (PSEs) on gut flora and faecal metabolites in rats with NAFLD. | 2020 | Details |
| A09292 | 31803542 | PeerJ | Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice. | 2019 | Details |
| A09300 | 31800592 | PLoS One | Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. | 2019 | Details |
| A09302 | 31799678 | Eur Rev Med Pharmacol Sci | MicroRNA-205 ameliorates lipid accumulation in non-alcoholic fatty liver disease through targeting NEU1. | 2019 | Details |
| A09308 | 31796953 | Am J Clin Nutr | Metabolic effects of a prolonged, very-high-dose dietary fructose challenge in healthy subjects. | 2020 | Details |
| A09309 | 31796646 | Aging (Albany NY) | HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway. | 2019 | Details |
| A09312 | 31795496 | Cells | Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins. | 2019 | Details |
| A09313 | 31795130 | Nutrients | Lotus Seedpod Extracts Reduced Lipid Accumulation and Lipotoxicity in Hepatocytes. | 2019 | Details |
| A09314 | 31793675 | J Food Biochem | Ganoderma polysaccharide and chitosan synergistically ameliorate lipid metabolic disorders and modulate gut microbiota composition in high fat diet-fed golden hamsters. | 2019 | Details |
| A09322 | 31790897 | Phytomedicine | Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates insulin resistance and hepatic steatosis via PI3K/Akt/GSK3β pathway. | 2019 | Details |
| A09337 | 31786336 | Biochim Biophys Acta Mol Basis Dis | Protective effect of metformin against palmitate-induced hepatic cell death. | 2019 | Details |
| A09354 | 31781248 | Stem Cells Int | Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice. | 2019 | Details |
| A09361 | 31777896 | Food Funct | Attenuation of metabolic syndrome in the ob/ob mouse model by resistant starch intervention is dose dependent. | 2019 | Details |
| A09367 | 31776016 | Environ Res | Adolescent exposure to environmental level of PCBs (Aroclor 1254) induces non-alcoholic fatty liver disease in male mice. | 2019 | Details |
| A09373 | 31771682 | Br J Nutr | Crude extract of Camellia oleifera pomace ameliorates the progression of non-alcoholic fatty liver disease via decreasing fat accumulation, insulin resistance and inflammation. | 2019 | Details |
| A09375 | 31771244 | Nutrients | Fat and Sugar-A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09376 | 31770672 | Mol Ther Nucleic Acids | Long Noncoding RNA lnc-HC Regulates PPARγ-Mediated Hepatic Lipid Metabolism through miR-130b-3p. | 2019 | Details |
| A09390 | 31765080 | Liver Int | Cellular endo-lysosomal dysfunction in the pathogenesis of non-alcoholic fatty liver disease. | 2019 | Details |
| A09393 | 31762148 | Liver Int | Dietary fatty acid oxidation is decreased in non-alcoholic fatty liver disease: A palmitate breath test study. | 2019 | Details |
| A09397 | 31760464 | Cell Mol Life Sci | Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis. | 2020 | Details |
| A09401 | 31759197 | J Nutr Biochem | Mitigation of nonalcoholic fatty liver disease in high-fat-fed mice by the combination of decaffeinated green tea extract and voluntary exercise. | 2019 | Details |
| A09402 | 31759125 | Peptides | The influence of Glucose-dependent Insulinotropic Polypeptide (GIP) on human adipose tissue and fat metabolism: Implications for obesity, type 2 diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD). | 2019 | Details |
| A09405 | 31758951 | Metabolism | Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. | 2019 | Details |
| A09410 | 31758299 | Rev Endocr Metab Disord | Ghrelin and liver disease. | 2020 | Details |
| A09419 | 31756997 | Metabolites | Glucose-6 Phosphate, A Central Hub for Liver Carbohydrate Metabolism. | 2019 | Details |
| A09428 | 31754142 | Sci Rep | New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery. | 2019 | Details |
| A09432 | 31752378 | Nutrients | Role of Probiotics in Non-alcoholic Fatty Liver Disease: Does Gut Microbiota Matter? | 2019 | Details |
| A09439 | 31749893 | Diabetol Metab Syndr | Long-term treatment with metformin in the prevention of fatty liver in Zucker diabetic fatty rats. | 2019 | Details |
| A09442 | 31748681 | Lab Invest | Maternal diet intervention before pregnancy primes offspring lipid metabolism in liver. | 2019 | Details |
| A09444 | 31746482 | Aliment Pharmacol Ther | Systematic review: chronic viral hepatitis and metabolic derangement. | 2019 | Details |
| A09449 | 31744059 | Mar Drugs | Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice. | 2019 | Details |
| A09453 | 31742325 | Clin Sci (Lond) | Processes exacerbating apoptosis in non-alcoholic steatohepatitis. | 2019 | Details |
| A09461 | 31734999 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of lipolipomics in primary hepatocellular carcinoma]. | 2019 | Details |
| A09472 | 31731192 | Biomed Pharmacother | Role of farnesoid X receptor in hepatic steatosis in nonalcoholic fatty liver disease. | 2019 | Details |
| A09474 | 31730978 | Int J Biol Macromol | Resistant starch from green banana (Musa sp.) attenuates non-alcoholic fat liver accumulation and increases short-chain fatty acids production in high-fat diet-induced obesity in mice. | 2019 | Details |
| A09475 | 31730885 | Toxicol Lett | In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. | 2019 | Details |
| A09476 | 31729980 | Lipids Health Dis | FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c. | 2019 | Details |
| A09480 | 31728041 | Sci Rep | Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism. | 2019 | Details |
| A09498 | 31718984 | J Pharm Biomed Anal | Metabolic impact of partial hepatectomy in the non-alcoholic steatohepatitis animal model of methionine-choline deficient diet. | 2019 | Details |
| A09503 | 31717842 | Nutrients | Efficacy and Mechanism of Polymerized Anthocyanin from Grape-Skin Extract on High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09505 | 31717414 | Int J Mol Sci | Lipid Related Genes Altered in NASH Connect Inflammation in Liver Pathogenesis Progression to HCC: A Canonical Pathway. | 2019 | Details |
| A09510 | 31715523 | J Nutr Biochem | Interactive effects of maternal and weaning high linoleic acid intake on hepatic lipid metabolism, oxylipins profile and hepatic steatosis in offspring. | 2019 | Details |
| A09514 | 31714387 | Eur J Gastroenterol Hepatol | Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome. | 2020 | Details |
| A09517 | 31713012 | Diabetologia | Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality. | 2019 | Details |
| A09527 | 31707624 | Rev Endocr Metab Disord | Dietary lipids, gut microbiota and lipid metabolism. | 2019 | Details |
| A09531 | 31706011 | Pharmacol Res | Combinational applicaton of silybin and tangeretin attenuates the progression of non-alcoholic steatohepatitis (NASH) in mice via modulating lipid metabolism. | 2019 | Details |
| A09536 | 31705397 | J Endocrinol Invest | L-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers. | 2019 | Details |
| A09546 | 31699440 | Environ Int | Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice. | 2019 | Details |
| A09549 | 31697646 | Aging (Albany NY) | Catalpol induces autophagy and attenuates liver steatosis in ob/ob and high-fat diet-induced obese mice. | 2019 | Details |
| A09551 | 31696774 | Gut Microbes | Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associated with biopsy-proven nonalcoholic steatohepatitis. | 2019 | Details |
| A09561 | 31694365 | Gut Liver | Downregulation of GNAI3 Promotes the Pathogenesis of Methionine/Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A09573 | 31690988 | Diabetologia | Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation. | 2019 | Details |
| A09585 | 31686320 | Sci China Life Sci | Regulation of glucose and lipid metabolism in health and disease. | 2019 | Details |
| A09587 | 31685793 | Nutr Diabetes | Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements. | 2019 | Details |
| A09590 | 31683679 | Molecules | Lipidomic Analysis of the Protective Effects of Shenling Baizhu San on Non-Alcoholic Fatty Liver Disease in Rats. | 2019 | Details |
| A09595 | 31682409 | Environ Sci Technol | Inhibition of Mitochondrial Fatty Acid Oxidation Contributes to Development of Nonalcoholic Fatty Liver Disease Induced by Environmental Cadmium Exposure. | 2019 | Details |
| A09603 | 31678070 | Metabolism | Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease. | 2019 | Details |