Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04352 | 33652261 | Biomed Pharmacother | Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury. | 2021 | Details |
| A04354 | 33650781 | Physiol Rep | Serum fetuin-A and Ser312 phosphorylated fetuin-A responses and markers of insulin sensitivity after a single bout of moderate intensity exercise. | 2021 | Details |
| A04357 | 33648885 | Obes Res Clin Pract | Comparison between non-invasive methods and liver histology to stratify liver fibrosis in obese patients submitted to bariatric surgery. | 2021 | Details |
| A04360 | 33647942 | Endocrinology | Hepatic Igf1-Deficiency Protects Against Atherosclerosis in Female Mice. | 2021 | Details |
| A04363 | 33647632 | Clin Imaging | Digital image analysis of ultrasound images using machine learning to diagnose pediatric nonalcoholic fatty liver disease. | 2021 | Details |
| A04367 | 33647205 | Chem Res Toxicol | LXRα/β Antagonism Protects against Lipid Accumulation in the Liver but Increases Plasma Cholesterol in Rhesus Macaques. | 2021 | Details |
| A04372 | 33643038 | Front Pharmacol | Gallic Acid Ameliorated Impaired Lipid Homeostasis in a Mouse Model of High-Fat Diet-and Streptozotocin-Induced NAFLD and Diabetes through Improvement of β-oxidation and Ketogenesis. | 2021 | Details |
| A04384 | 33640265 | J Diabetes Complications | Serum uric acid is positively associated with the prevalence of nonalcoholic fatty liver in non-obese type 2 diabetes patients in a Chinese population. | 2021 | Details |
| A04392 | 33637021 | Thyroid | Comparative Analysis of the Effects of Long-Term 3,5-diiodothyronine Treatment on the Murine Hepatic Proteome and Transcriptome Under Conditions of Normal Diet and High-Fat Diet. | 2021 | Details |
| A04393 | 33636655 | Clin Res Hepatol Gastroenterol | Prevalence and clinical characteristics of alpha-1 antitrypsin deficiency in liver explants in a Mexican cohort. | 2021 | Details |
| A04395 | 33636024 | Hepatology | Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α. | 2021 | Details |
| A04399 | 33633080 | J Pediatr Gastroenterol Nutr | Clinical and Esophagogastroduodenoscopy Findings in Pediatric Patients With Severe Obesity Evaluated Before Bariatric Surgery. | 2021 | Details |
| A04400 | 33632710 | Gut | From the origin of NASH to the future of metabolic fatty liver disease. | 2021 | Details |
| A04410 | 33629536 | Mol Nutr Food Res | Effect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial. | 2021 | Details |
| A04411 | 33628759 | Can J Gastroenterol Hepatol | Assessment of Steatosis and Fibrosis in Liver Transplant Recipients Using Controlled Attenuation Parameter and Liver Stiffness Measurements. | 2021 | Details |
| A04412 | 33628758 | Can J Gastroenterol Hepatol | Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity. | 2021 | Details |
| A04413 | 33628620 | Oncoimmunology | Increase of α-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer. | 2021 | Details |
| A04414 | 33628193 | Front Pharmacol | Fructose and Non-Alcoholic Steatohepatitis. | 2021 | Details |
| A04415 | 33627704 | Sci Rep | The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates. | 2021 | Details |
| A04418 | 33626072 | PLoS One | Characteristics of bile acid composition in high fat diet-induced nonalcoholic fatty liver disease in obese diabetic rats. | 2021 | Details |
| A04422 | 33622266 | BMC Gastroenterol | The role of PNPLA3 and TM6SF2 polymorphisms on liver fibrosis and metabolic abnormalities in Brazilian patients with chronic hepatitis C. | 2021 | Details |
| A04423 | 33622213 | Am J Chin Med | Intestinal Flora: A Pivotal Role in Investigation of Traditional Chinese Medicine. | 2021 | Details |
| A04428 | 33619282 | Nat Commun | Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation. | 2021 | Details |
| A04429 | 33618924 | Nutr Metab Cardiovasc Dis | Serum leptin as a mediator of the influence of insulin resistance on hepatic steatosis in youths with excess adiposity. | 2021 | Details |
| A04431 | 33618780 | Br J Nutr | Dietary and metabolic risk of neuropsychiatric disorders: insights from animal models. | 2021 | Details |
| A04436 | 33616848 | Obes Surg | Performance of Noninvasive Liver Fibrosis Tests in Morbidly Obese Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04443 | 33615207 | JHEP Rep | NASH-related increases in plasma bile acid levels depend on insulin resistance. | 2020 | Details |
| A04445 | 33614318 | Cureus | Treatment of Fatty Liver Disease: The Present and the Future. | 2021 | Details |
| A04449 | 33612041 | Chronobiol Int | Different expressions of clock genes in fatty liver induced by high-sucrose and high-fat diets. | 2021 | Details |
| A04458 | 33608323 | Dis Model Mech | High-dose vitamin B1 therapy prevents the development of experimental fatty liver driven by overnutrition. | 2021 | Details |
| A04460 | 33608033 | Nutr Metab (Lond) | Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals. | 2021 | Details |
| A04465 | 33604257 | J Clin Transl Hepatol | Diversity in NAFLD: A Review of Manifestations of Nonalcoholic Fatty Liver Disease in Different Ethnicities Globally. | 2020 | Details |
| A04472 | 33603757 | Front Immunol | Extracellular Vesicles as Inflammatory Drivers in NAFLD. | 2021 | Details |
| A04474 | 33603666 | Front Pharmacol | The Role of Bone Morphogenetic Protein 9 in Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A04479 | 33601216 | Nutr Res | G protein-coupled receptors: Key molecules in metabolic associated fatty liver disease development. | 2020 | Details |
| A04483 | 33600104 | Clin Transl Gastroenterol | Implications of Abdominal Adipose Tissue Distribution on Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: A Chinese General Population Study. | 2021 | Details |
| A04487 | 33599159 | Expert Opin Pharmacother | An update on pharmacotherapeutic strategies for obesity. | 2021 | Details |
| A04489 | 33598160 | Food Sci Nutr | The protective effect of sulforaphane on type II diabetes induced by high-fat diet and low-dosage streptozotocin. | 2020 | Details |
| A04490 | 33598084 | Pan Afr Med J | Interest of hepatic steatosis index (HSI) in screening for metabolic steatopathy in patients with type 2 diabetes. | 2020 | Details |
| A04501 | 33595790 | Obes Surg | Outcomes of Bariatric Surgery in Patients with Liver Cirrhosis: a Systematic Review. | 2021 | Details |
| A04514 | 33592199 | Life Sci | Non-alcoholic fatty liver disease: An overview of risk factors, pathophysiological mechanisms, diagnostic procedures, and therapeutic interventions. | 2021 | Details |
| A04522 | 33588049 | Free Radic Biol Med | Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling. | 2021 | Details |
| A04527 | 33586569 | Int J Food Sci Nutr | Reduced plasma carotenoids in individuals suffering from metabolic diseases with disturbances in lipid metabolism: a systematic review and meta-analysis of observational studies. | 2021 | Details |
| A04537 | 33584555 | Front Microbiol | The Therapeutic Efficacy of Curcumin vs. Metformin in Modulating the Gut Microbiota in NAFLD Rats: A Comparative Study. | 2021 | Details |
| A04538 | 33584545 | Front Endocrinol (Lausanne) | TLR9 in MAFLD and NASH: At the Intersection of Inflammation and Metabolism. | 2021 | Details |
| A04542 | 33584134 | J Med Biochem | The role of oxidative stress in the development of obesity and obesity-related metabolic disorders. | 2021 | Details |
| A04545 | 33583934 | J Epidemiol | Association between nutrient patterns and fatty liver index: Baseline survey of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima, Japan. | 2021 | Details |
| A04546 | 33583577 | Clin Ther | Therapy for Nonalcoholic Fatty Liver Disease: Current Options and Future Directions. | 2021 | Details |
| A04547 | 33583033 | Eur J Clin Invest | Nonalcoholic fatty liver disease or metabolic dysfunction-associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches. | 2021 | Details |
| A04552 | 33581653 | Biomed Pharmacother | Danthron ameliorates obesity and MAFLD through activating the interplay between PPARα/RXRα heterodimer and adiponectin receptor 2. | 2021 | Details |
| A04558 | 33580458 | Mol Biol Rep | Evaluating the effect of a mixture of two main conjugated linoleic acid isomers on hepatic steatosis in HepG2 cellular model. | 2021 | Details |
| A04559 | 33580453 | Hepatol Int | The epidemiology of NAFLD and lean NAFLD in Japan: a meta-analysis with individual and forecasting analysis, 1995-2040. | 2021 | Details |
| A04560 | 33580177 | Sci Rep | Nonalcoholic fatty liver disease and the risk of atrial fibrillation stratified by body mass index: a nationwide population-based study. | 2021 | Details |
| A04562 | 33579423 | Adv Cancer Res | NAFLD-related HCC. | 2021 | Details |
| A04563 | 33579000 | Int J Mol Sci | IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes. | 2021 | Details |
| A04569 | 33577920 | J Hepatol | Diagnosis and management of secondary causes of steatohepatitis. | 2021 | Details |
| A04574 | 33575290 | Hepatobiliary Surg Nutr | Hepatocellular carcinoma in non-alcoholic fatty liver disease-a review of an emerging challenge facing clinicians. | 2021 | Details |
| A04575 | 33574841 | Int J Endocrinol | Evaluation of Different Anthropometric Indicators for Screening for Nonalcoholic Fatty Liver Disease in Elderly Individuals. | 2021 | Details |
| A04576 | 33574823 | Front Immunol | Self-Nucleic Acid Sensing: A Novel Crucial Pathway Involved in Obesity-Mediated Metaflammation and Metabolic Syndrome. | 2021 | Details |
| A04577 | 33574818 | Front Immunol | Predicting Non-Alcoholic Fatty Liver Disease Progression and Immune Deregulations by Specific Gene Expression Patterns. | 2021 | Details |
| A04581 | 33573745 | J Am Coll Cardiol | Leptin in Leanness and Obesity: JACC State-of-the-Art Review. | 2021 | Details |
| A04584 | 33572810 | Nutrients | Krill Oil Supplementation Reduces Exacerbated Hepatic Steatosis Induced by Thermoneutral Housing in Mice with Diet-Induced Obesity. | 2021 | Details |
| A04585 | 33572797 | Cancers (Basel) | The Current View of Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma. | 2021 | Details |
| A04588 | 33572376 | J Clin Med | Non-Alcoholic Fatty Liver in Patients with Chylomicronemia. | 2021 | Details |
| A04591 | 33571540 | Metabolism | The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling. | 2021 | Details |
| A04594 | 33569991 | Arch Physiol Biochem | The potential of Artemisia species for use as broad-spectrum agents in the management of metabolic syndrome: a review. | 2021 | Details |
| A04597 | 33568925 | Diabetes Metab Syndr Obes | The Impact of Vitamin D in Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study in Patients with Morbid Obesity. | 2021 | Details |
| A04599 | 33568418 | BMJ Open Gastroenterol | Detecting non-alcoholic fatty liver disease and risk factors in health databases: accuracy and limitations of the ICD-10-AM. | 2021 | Details |
| A04604 | 33566371 | FASEB J | NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response. | 2021 | Details |
| A04613 | 33562473 | Biology (Basel) | Relationship between Muscle Mass and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04619 | 33560577 | Mol Nutr Food Res | Three Novel Dietary Phenolic Compounds from Pickled Raphanus Sativus L. Inhibit Lipid Accumulation in Obese Mice by Modulating the Gut Microbiota Composition. | 2021 | Details |
| A04623 | 33559369 | Mol Nutr Food Res | Black Current Anthocyanins Improve Lipid Metabolism and Modulate Gut Microbiota in High-Fat Diet-Induced Obese Mice. | 2021 | Details |
| A04624 | 33559089 | Dig Dis Sci | Performance of Serum-Based Scores for Identification of Mild Hepatic Steatosis in HBV Mono-infected and HBV-HIV Co-infected Adults. | 2021 | Details |
| A04625 | 33559024 | Biol Trace Elem Res | Nonalcoholic Steatohepatitis Modifies Serum Iron-Related Variables in Patients with Morbid Obesity. | 2021 | Details |
| A04627 | 33558081 | Mol Genet Metab | US-FLI score - Is it possible to predict the steatosis grade with an ultrasonographic score? | 2021 | Details |
| A04628 | 33557653 | Expert Rev Gastroenterol Hepatol | Hepatocyte and immune cell crosstalk in non-alcoholic fatty liver disease. | 2021 | Details |
| A04629 | 33557355 | Life (Basel) | Sarcopenic Obesity in Non-Alcoholic Fatty Liver Disease-The Union of Two Culprits. | 2021 | Details |
| A04636 | 33555523 | J Gastrointest Surg | Gastric Bypass Increases Circulating Bile Acids and Activates Hepatic Farnesoid X Receptor (FXR) but Requires Intact Peroxisome Proliferator Activator Receptor Alpha (PPARα) Signaling to Significantly Reduce Liver Fat Content. | 2021 | Details |
| A04637 | 33555168 | Clin Transl Gastroenterol | Clinical and Genetic Risk Factors of Recurrent Nonalcoholic Fatty Liver Disease After Liver Transplantation. | 2021 | Details |
| A04641 | 33554097 | JHEP Rep | Non-alcoholic fatty liver disease does not increase dementia risk although histology data might improve risk prediction. | 2020 | Details |
| A04642 | 33554072 | iScience | Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation. | 2021 | Details |
| A04649 | 33552218 | Evid Based Complement Alternat Med | Probiotics as a Complementary Therapy for Management of Obesity: A Systematic Review. | 2021 | Details |
| A04651 | 33551215 | Clin Nutr | Fructose intake is not associated to the risk of hepatic fibrosis in patients with Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A04652 | 33550706 | Liver Int | Effects of two personalized dietary strategies during a 2-year intervention in subjects with nonalcoholic fatty liver disease: A randomized trial. | 2021 | Details |
| A04660 | 33548473 | J Nutr Biochem | Tomatidine ameliorates obesity-induced nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A04667 | 33546405 | Nutrients | Effects of Long-Term DHA Supplementation and Physical Exercise on Non-Alcoholic Fatty Liver Development in Obese Aged Female Mice. | 2021 | Details |
| A04668 | 33546191 | Biomedicines | Insights into the Impact of Microbiota in the Treatment of NAFLD/NASH and Its Potential as a Biomarker for Prognosis and Diagnosis. | 2021 | Details |
| A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04673 | 33545430 | Cell Mol Gastroenterol Hepatol | Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH. | 2021 | Details |
| A04685 | 33542911 | Can J Gastroenterol Hepatol | Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice. | 2021 | Details |
| A04688 | 33541866 | Gut | Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach? | 2021 | Details |
| A04692 | 33539004 | Hepatol Int | The metabolic profiles and body composition of lean metabolic associated fatty liver disease. | 2021 | Details |
| A04693 | 33538526 | Gastroenterol Nurs | Gut Microbiome and Nonalcoholic Fatty Liver Disease (NAFLD): Implications for Nursing Care of Individuals Living With Chronic Metabolic Diseases. | 2021 | Details |
| A04698 | 33536442 | Sci Rep | Clinical implications of renin-angiotensin system inhibitors for development and progression of non-alcoholic fatty liver disease. | 2021 | Details |
| A04699 | 33536048 | Nutr Metab (Lond) | Effectiveness of companion-intensive multi-aspect weight management in Chinese adults with obesity: a 6-month multicenter randomized clinical trial. | 2021 | Details |
| A04703 | 33535211 | Dig Dis | NASH/Liver Fibrosis Prevalence and Incidence of Nonliver Comorbidities among People with NAFLD and Incidence of NAFLD by Metabolic Comorbidities: Lessons from South Korea. | 2021 | Details |
| A04705 | 33535004 | Scand J Gastroenterol | Visceral fat area to appendicular muscle mass ratio as a predictor for nonalcoholic fatty liver disease independent of obesity. | 2021 | Details |
| A04712 | 33531899 | Int J Endocrinol | Osteocalcin Alleviates Nonalcoholic Fatty Liver Disease in Mice through GPRC6A. | 2021 | Details |
| A04716 | 33530440 | J Clin Med | NAFLD and Cardiovascular Diseases: Epidemiological, Mechanistic and Therapeutic Considerations. | 2021 | Details |
| A04721 | 33529448 | Liver Int | Maternal high-fat diet disrupted one-carbon metabolism in offspring, contributing to nonalcoholic fatty liver disease. | 2021 | Details |