Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A14279 | 29486218 | Toxicology | Cadmium exposure exacerbates hyperlipidemia in cholesterol-overloaded hepatocytes via autophagy dysregulation. | 2018 | Details |
| A14301 | 29474931 | Biochim Biophys Acta Mol Cell Biol Lipids | Alpha-syntrophin null mice are protected from non-alcoholic steatohepatitis in the methionine-choline-deficient diet model but not the atherogenic diet model. | 2018 | Details |
| A14302 | 29473277 | Hepatol Res | Formation of p62-positive inclusion body is associated with macrophage polarization in non-alcoholic fatty liver disease. | 2018 | Details |
| A14323 | 29466466 | PLoS One | Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. | 2018 | Details |
| A14325 | 29464180 | Int J Genomics | Lingguizhugan Decoction Protects against High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease by Alleviating Oxidative Stress and Activating Cholesterol Secretion. | 2017 | Details |
| A14330 | 29463133 | Arch Physiol Biochem | Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis, oxidative stress, and inflammatory biomarkers in the liver of old rats with non-alcoholic fatty liver disease. | 2018 | Details |
| A14344 | 29454969 | Biochem Biophys Res Commun | JIP3 knockout protects mice against high fat diet-induced liver injury. | 2018 | Details |
| A14345 | 29454967 | Biochem Biophys Res Commun | SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation. | 2018 | Details |
| A14358 | 29450137 | Biochim Open | Liver and Metformin: Lessons of a fructose diet in mice. | 2017 | Details |
| A14361 | 29447962 | Int J Biol Macromol | Low molecular weight fucoidan attenuates liver injury via SIRT1/AMPK/PGC1α axis in db/db mice. | 2018 | Details |
| A14385 | 29432786 | Biochimie | Oleic acid induces the novel apolipoprotein O and reduces mitochondrial membrane potential in chicken and human hepatoma cells. | 2018 | Details |
| A14391 | 29430321 | Liver Res | Interaction between stress responses and circadian metabolism in metabolic disease. | 2017 | Details |
| A14395 | 29428667 | Biomed Pharmacother | Silybum marianum oil attenuates hepatic steatosis and oxidative stress in high fat diet-fed mice. | 2018 | Details |
| A14400 | 29427492 | Liver Int | Future therapy for non-alcoholic fatty liver disease. | 2018 | Details |
| A14421 | 29414684 | Cell Metab | Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis. | 2018 | Details |
| A14424 | 29413959 | Redox Biol | Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches. | 2018 | Details |
| A14431 | 29409822 | Metabolism | Serum levels of advanced glycation end-products (AGEs) and the decoy soluble receptor for AGEs (sRAGE) can identify non-alcoholic fatty liver disease in age-, sex- and BMI-matched normo-glycemic adults. | 2018 | Details |
| A14457 | 29402657 | Diabetes Metab Syndr | Nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus and its association with cardiovascular disease. | 2018 | Details |
| A14458 | 29401710 | Nutrients | Dietary Iron Supplementation Alters Hepatic Inflammation in a Rat Model of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A14461 | 29400110 | Free Radic Res | Scutellarin ameliorates nonalcoholic fatty liver disease through the PPARγ/PGC-1α-Nrf2 pathway. | 2018 | Details |
| A14467 | 29399273 | World J Hepatol | Role of inflammatory response in liver diseases: Therapeutic strategies. | 2018 | Details |
| A14481 | 29391222 | Adv Drug Deliv Rev | MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis. | 2018 | Details |
| A14487 | 29386434 | Yakugaku Zasshi | [From a Ph.D. Thesis: Understanding the Past, Predicting the Future]. | 2018 | Details |
| A14490 | 29385682 | Nutrients | Serum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Study. | 2018 | Details |
| A14504 | 29378152 | Can J Physiol Pharmacol | Beneficial effects of N-acetylcysteine on hepatic oxidative stress in streptozotocin-induced diabetic rats. | 2018 | Details |
| A14531 | 29366871 | Food Chem Toxicol | Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. | 2018 | Details |
| A14536 | 29364090 | Acta Gastroenterol Belg | Serum concentrations of Cyclophilin A in patients with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A14563 | 29353208 | Biomed Pharmacother | Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatin. | 2018 | Details |
| A14567 | 29350757 | J Food Sci | Hepatoprotective Effects of Sophoricoside against Fructose-Induced Liver Injury via Regulating Lipid Metabolism, Oxidation, and Inflammation in Mice. | 2018 | Details |
| A14572 | 29348746 | Gastroenterol Res Pract | Impact of Time-Restricted Feeding and Dawn-to-Sunset Fasting on Circadian Rhythm, Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14582 | 29341349 | Pathol Int | Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease. | 2018 | Details |
| A14586 | 29337849 | Antioxidants (Basel) | Vitamin E as a Treatment for Nonalcoholic Fatty Liver Disease: Reality or Myth? | 2018 | Details |
| A14598 | 29331340 | J Hepatol | Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling. | 2018 | Details |
| A14601 | 29329924 | Nutr Metab Cardiovasc Dis | Effects of dark chocolate on endothelial function in patients with non-alcoholic steatohepatitis. | 2017 | Details |
| A14604 | 29327118 | Sleep Breath | Effect of CPAP therapy on liver disease in patients with OSA: a review. | 2018 | Details |
| A14615 | 29322801 | Bratisl Lek Listy | Paraoxonase activity in sera of patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A14616 | 29322544 | Aliment Pharmacol Ther | Role of bisphenol A as environmental factor in the promotion of non-alcoholic fatty liver disease: in vitro and clinical study. | 2018 | Details |
| A14647 | 29310441 | Antioxid Redox Signal | Dihydromyricetin Ameliorates Nonalcoholic Fatty Liver Disease by Improving Mitochondrial Respiratory Capacity and Redox Homeostasis Through Modulation of SIRT3 Signaling. | 2018 | Details |
| A14649 | 29309075 | Food Funct | Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation. | 2018 | Details |
| A14671 | 29294263 | Postepy Biochem | [NAFLD pathogenesis in the light of recent research]. | 2019 | Details |
| A14680 | 29289645 | Mol Metab | Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease. | 2017 | Details |
| A14682 | 31938096 | Int J Clin Exp Pathol | A nonalcoholic fatty liver disease cirrhosis model in gerbil: the dynamic relationship between hepatic lipid metabolism and cirrhosis. | 2018 | Details |
| A14689 | 29288054 | Int J Biochem Cell Biol | Mitochondria in non-alcoholic fatty liver disease. | 2017 | Details |
| A14692 | 29287685 | Pharmacol Res | Medicinal plants and bioactive natural compounds in the treatment of non-alcoholic fatty liver disease: A clinical review. | 2017 | Details |
| A14711 | 29276754 | Cell Mol Gastroenterol Hepatol | Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model. | 2017 | Details |
| A14714 | 29274591 | Biomed Pharmacother | Extract of Citrus maxima (pummelo) leaves improve hepatoprotective activity in Wistar rats submitted to the induction of non-alcoholic hepatic steatosis. | 2017 | Details |
| A14726 | 29270247 | Oxid Med Cell Longev | Deficiency of the Purinergic Receptor 2X7 Attenuates Nonalcoholic Steatohepatitis Induced by High-Fat Diet: Possible Role of the NLRP3 Inflammasome. | 2017 | Details |
| A14731 | 29268106 | J Nutr Biochem | Food components with antifibrotic activity and implications in prevention of liver disease. | 2017 | Details |
| A14751 | 29255346 | Drug Des Devel Ther | Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes. | 2017 | Details |
| A14761 | 29249967 | Front Pharmacol | Psoralea corylifolia L. Attenuates Nonalcoholic Steatohepatitis in Juvenile Mouse. | 2017 | Details |
| A14764 | 29249184 | Hum Exp Toxicol | Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention. | 2017 | Details |
| A14768 | 29247950 | Biomed Pharmacother | Baicalin attenuates diet induced nonalcoholic steatohepatitis by inhibiting inflammation and oxidative stress via suppressing JNK signaling pathways. | 2017 | Details |
| A14771 | 29247356 | J Gastroenterol | Current and future pharmacological therapies for NAFLD/NASH. | 2017 | Details |
| A14772 | 29247122 | FASEB J | Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice. | 2017 | Details |
| A14793 | 29229391 | Biochem Biophys Res Commun | Hepatocyte-specific clusterin overexpression attenuates diet-induced nonalcoholic steatohepatitis. | 2017 | Details |
| A14802 | 29224910 | Arch Med Res | Regulation of SIRT3/FOXO1 Signaling Pathway in Rats with Non-alcoholic Steatohepatitis by Salvianolic Acid B. | 2017 | Details |
| A14815 | 29222421 | Sci Rep | The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14820 | 29220698 | Redox Biol | Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression. | 2017 | Details |
| A14832 | 29214926 | Nutr Health | Aerobic training performed at ventilatory threshold improves liver enzymes and lipid profile related to non-alcoholic fatty liver disease in adolescents with obesity. | 2017 | Details |
| A14854 | 29203247 | Biochem Biophys Res Commun | Co-administration of APD668, a G protein-coupled receptor 119 agonist and linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in mice fed on a high trans-fat diet. | 2017 | Details |
| A14867 | 29199410 | Diabetes Metab J | Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases. | 2017 | Details |
| A14887 | 29190550 | J Nutr Biochem | Green tea extract protects against hepatic NFκB activation along the gut-liver axis in diet-induced obese mice with nonalcoholic steatohepatitis by reducing endotoxin and TLR4/MyD88 signaling. | 2017 | Details |
| A14905 | 29180630 | Sci Rep | ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish. | 2017 | Details |
| A14906 | 29179698 | BMC Gastroenterol | Fast food diet-induced non-alcoholic fatty liver disease exerts early protective effect against acetaminophen intoxication in mice. | 2017 | Details |
| A14913 | 29175669 | J Nutr Biochem | Euterpe oleracea Mart. (açaí) seed extract associated with exercise training reduces hepatic steatosis in type 2 diabetic male rats. | 2017 | Details |
| A14920 | 29174039 | Biomed Pharmacother | Lavatera critica, a green leafy vegetable, controls high fat diet induced hepatic lipid accumulation and oxidative stress through the regulation of lipogenesis and lipolysis genes. | 2017 | Details |
| A14922 | 29172017 | Med Sci Monit | Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats. | 2017 | Details |
| A14950 | 29159325 | Hepatol Commun | Role of Aramchol in steatohepatitis and fibrosis in mice. | 2017 | Details |
| A14953 | 29158183 | Biochim Biophys Acta Mol Basis Dis | Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes. | 2017 | Details |
| A14955 | 29158088 | Biochem Biophys Res Commun | Interplay of adipocyte and hepatocyte: Leptin upregulates hepcidin. | 2017 | Details |
| A14957 | 29156529 | Biomed Pharmacother | Alpinetin improved high fat diet-induced non-alcoholic fatty liver disease (NAFLD) through improving oxidative stress, inflammatory response and lipid metabolism. | 2017 | Details |
| A14963 | 29154964 | J Hepatol | Lipotoxicity and the gut-liver axis in NASH pathogenesis. | 2017 | Details |
| A14964 | 29154469 | Pathol Int | Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features. | 2017 | Details |
| A14971 | 29150932 | J Cell Physiol | High fat diet-induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice. | 2018 | Details |
| A14972 | 29150621 | Sci Rep | PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress. | 2017 | Details |
| A14984 | 29141573 | Endocr Metab Immune Disord Drug Targets | Liver Protective Effects of Extra Virgin Olive Oil: Interaction between Its Chemical Composition and the Cell-signaling Pathways Involved in Protection. | 2018 | Details |
| A14990 | 29136950 | Biomed Pharmacother | A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cells. | 2017 | Details |
| A14999 | 29129819 | Metabolism | Nicotinic acetylcholine receptor α7 subunit improves energy homeostasis and inhibits inflammation in nonalcoholic fatty liver disease. | 2017 | Details |
| A15000 | 29129237 | Nutrition | Iron-induced pro-oxidant and pro-lipogenic responses in relation to impaired synthesis and accretion of long-chain polyunsaturated fatty acids in rat hepatic and extrahepatic tissues. | 2017 | Details |
| A15010 | 29128059 | Clin Liver Dis | Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15066 | 29112771 | Clin Exp Pharmacol Physiol | Role of mitochondria and mitochondria-targeted agents in non-alcoholic fatty liver disease. | 2017 | Details |
| A15085 | 29104232 | Antioxidants (Basel) | Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes. | 2017 | Details |
| A15099 | 29097281 | Biochimie | Steatosis and NASH in type 2 diabetes. | 2017 | Details |
| A15122 | 29085222 | World J Gastroenterol | Intrahepatic vascular changes in non-alcoholic fatty liver disease: Potential role of insulin-resistance and endothelial dysfunction. | 2017 | Details |
| A15133 | 29081885 | Oxid Med Cell Longev | Dietary Flaxseed Oil Prevents Western-Type Diet-Induced Nonalcoholic Fatty Liver Disease in Apolipoprotein-E Knockout Mice. | 2017 | Details |
| A15157 | 29069580 | Eur J Pharmacol | Nicotinamide prevents sweet beverage-induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress. | 2017 | Details |
| A15186 | 29057834 | Nutrients | Non-Alcoholic Fatty Liver Disease and Nutritional Implications: Special Focus on Copper. | 2017 | Details |
| A15205 | 29050312 | Oncotarget | Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage. | 2017 | Details |
| A15221 | 29038049 | Biochim Biophys Acta Mol Basis Dis | Inhibition of EGFR attenuates fibrosis and stellate cell activation in diet-induced model of nonalcoholic fatty liver disease. | 2017 | Details |
| A15229 | 29035092 | Crit Rev Food Sci Nutr | Vitamin D supplementation and non-alcoholic fatty liver disease: A critical and systematic review of clinical trials. | 2017 | Details |
| A15231 | 29034200 | J Tradit Complement Med | Promising effect of Rosa damascena extract on high-fat diet-induced nonalcoholic fatty liver. | 2017 | Details |
| A15232 | 29031784 | J Ethnopharmacol | Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats. | 2017 | Details |
| A15234 | 29031535 | Chem Biol Interact | Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation. | 2017 | Details |
| A15237 | 29028831 | PLoS One | Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice. | 2017 | Details |
| A15247 | 29024899 | Biomed Pharmacother | Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice. | 2017 | Details |
| A15252 | 29023783 | J Cell Physiol | Melatonin application in targeting oxidative-induced liver injuries: A review. | 2017 | Details |
| A15253 | 29023387 | Nutrients | Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet. | 2017 | Details |
| A15257 | 29022011 | Heliyon | Placental extract ameliorates non-alcoholic steatohepatitis (NASH) by exerting protective effects on endothelial cells. | 2017 | Details |
| A15260 | 29018509 | Oxid Med Cell Longev | circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis. | 2017 | Details |
| A15281 | 28988798 | Free Radic Biol Med | Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH. | 2017 | Details |