Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08312 | 32156524 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |
| A08314 | 32156227 | Curr Pharm Des | Modifiers of Liver-Related Manifestation in the Course of NAFLD. | 2020 | Details |
| A08322 | 32152902 | Indian J Gastroenterol | Treatment of non-alcoholic fatty liver disease - Current perspectives. | 2020 | Details |
| A08324 | 32152511 | Eur J Clin Nutr | Association of grip strength with non-alcoholic fatty liver disease: investigation of the roles of insulin resistance and inflammation as mediators. | 2020 | Details |
| A08325 | 32152478 | Nat Rev Gastroenterol Hepatol | Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders. | 2020 | Details |
| A08328 | 32151552 | Surg Obes Relat Dis | Management of nonalcoholic fatty liver disease and the role of bariatric surgery: a brief review for surgeons. | 2020 | Details |
| A08330 | 32150756 | Hepatology | N6 -Methyladenosine Reader Protein YT521-B Homology Domain-Containing 2 Suppresses Liver Steatosis by Regulation of mRNA Stability of Lipogenic Genes. | 2020 | Details |
| A08336 | 32149275 | JHEP Rep | Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism. | 2019 | Details |
| A08339 | 32148405 | J Ginseng Res | Ginseng-plus-Bai-Hu-Tang ameliorates diet-induced obesity, hepatic steatosis, and insulin resistance in mice. | 2018 | Details |
| A08341 | 32147363 | J Hepatol | Newly identified peptide hormone inhibits intestinal fat absorption and improves NAFLD through its receptor GPRC6A. | 2020 | Details |
| A08349 | 32146441 | J Pediatr Endocrinol Metab | Utility of MR proton density fat fraction and its correlation with ultrasonography and biochemical markers in nonalcoholic fatty liver disease in overweight adolescents. | 2020 | Details |
| A08351 | 32145387 | Prostaglandins Other Lipid Mediat | Lipocalin-type prostaglandin D2 synthase deletion induces dyslipidemia and non-alcoholic fatty liver disease. | 2020 | Details |
| A08353 | 32145306 | Life Sci | Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol. | 2020 | Details |
| A08361 | 32143931 | J Pediatr | Genetic Risk for Hepatic Fat among an Ethnically Diverse Cohort of Youth: The Exploring Perinatal Outcomes among Children Study. | 2020 | Details |
| A08366 | 32142998 | Diabetes Metab Syndr | rs7903146 (C/T) polymorphism of Transcription factor 7 like 2 (TCF7L-2) gene is independently associated with non-alcoholic fatty liver disease in Asian Indians. | 2020 | Details |
| A08379 | 32135178 | J Hepatol | Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis. | 2020 | Details |
| A08382 | 32132708 | Nature | Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis. | 2020 | Details |
| A08388 | 32130386 | Rev Assoc Med Bras (1992) | Non-alcoholic fatty liver disease in patients infected with human immunodeficiency virus: a systematic review. | 2020 | Details |
| A08390 | 32128995 | Pediatr Obes | Effects of a carbohydrate-restricted diet on hepatic lipid content in adolescents with non-alcoholic fatty liver disease: A pilot, randomized trial. | 2020 | Details |
| A08393 | 32128893 | J Gastroenterol Hepatol | Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway. | 2020 | Details |
| A08448 | 32106111 | JCI Insight | Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly. | 2020 | Details |
| A08450 | 32105829 | Free Radic Biol Med | 17β-estradiol ameliorates lipotoxicity-induced hepatic mitochondrial oxidative stress and insulin resistance. | 2020 | Details |
| A08460 | 32103588 | Mol Nutr Food Res | Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases. | 2020 | Details |
| A08461 | 32102936 | Sci Transl Med | Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance. | 2020 | Details |
| A08465 | 32100496 | Zhongguo Zhen Jiu | [Electroacupuncture combined with lifestyle control on obese nonalcoholic fatty liver disease: a randomized controlled trial]. | 2020 | Details |
| A08474 | 32096565 | Hepatology | Cardiolipin Synthase 1 Ameliorates NASH Through Activating Transcription Factor 3 Transcriptional Inactivation. | 2020 | Details |
| A08482 | 32092735 | Biomed Res | Placental extract ameliorates liver fibrosis in a methionine- and choline-deficient diet-induced mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A08497 | 32086249 | Biol Open | Long-term sucrose solution consumption causes metabolic alterations and affects hepatic oxidative stress in Wistar rats. | 2020 | Details |
| A08502 | 32083947 | Can J Physiol Pharmacol | Combined treatments with metformin and phosphodiesterase inhibitors alleviate nonalcoholic fatty liver disease in high-fat diet fed rats: a comparative study. | 2020 | Details |
| A08510 | 32081727 | Mitochondrion | Mitochondrial dysfunction: An emerging link in the pathophysiology of polycystic ovary syndrome. | 2020 | Details |
| A08512 | 32077835 | Endocr Metab Immune Disord Drug Targets | Prevalence of Nonalcoholic Fatty Liver Disease in Familial Mediterranean Fever. | 2020 | Details |
| A08513 | 32077785 | Metab Syndr Relat Disord | Role of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Oxidative Stress-Associated Metabolic Diseases. | 2020 | Details |
| A08522 | 32075905 | J Biol Chem | Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice. | 2020 | Details |
| A08525 | 32074961 | Nutrients | Dietary Platycodon grandiflorus Attenuates Hepatic Insulin Resistance and Oxidative Stress in High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A08540 | 32068022 | Gastroenterology | Metabolic Inflammation-A Role for Hepatic Inflammatory Pathways as Drivers of Comorbidities in Nonalcoholic Fatty Liver Disease? | 2020 | Details |
| A08556 | 32062042 | Clin Gastroenterol Hepatol | Development and Validation of a Scoring System, Based on Genetic and Clinical Factors, to Determine Risk of Steatohepatitis in Asian Patients with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08558 | 32061598 | Gastroenterology | Adipose Tissue-Liver Cross Talk in the Control of Whole-Body Metabolism: Implications in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08566 | 32059982 | J Hepatol | NAFLD as a driver of chronic kidney disease. | 2020 | Details |
| A08567 | 32058943 | EBioMedicine | Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes. | 2020 | Details |
| A08577 | 32054379 | J Recept Signal Transduct Res | Inevitable role of TGF-β1 in progression of nonalcoholic fatty liver disease. | 2020 | Details |
| A08582 | 32051820 | Can J Gastroenterol Hepatol | Natural History of Nonalcoholic Fatty Liver Disease: Implications for Clinical Practice and an Individualized Approach. | 2020 | Details |
| A08583 | 32051143 | J Biol Chem | Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease. | 2020 | Details |
| A08586 | 32049638 | BMJ Open Diabetes Res Care | Insulin resistance, beta-cell function, adipokine profiles and cardiometabolic risk factors among Chinese youth with isolated impaired fasting glucose versus impaired glucose tolerance: the BCAMS study. | 2020 | Details |
| A08604 | 32044284 | Clin Res Hepatol Gastroenterol | Does adipose tissue inflammation drive the development of non-alcoholic fatty liver disease in obesity? | 2020 | Details |
| A08606 | 32043636 | FASEB J | REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. | 2020 | Details |
| A08622 | 32039394 | JHEP Rep | Endoscopic duodenal mucosal resurfacing improves glycaemic and hepatic indices in type 2 diabetes: 6-month multicentre results. | 2019 | Details |
| A08626 | 32039376 | JHEP Rep | Comparison between non-alcoholic fatty liver disease screening guidelines in children and adolescents. | 2019 | Details |
| A08633 | 32038642 | Front Immunol | The Interplay Between Tissue Niche and Macrophage Cellular Metabolism in Obesity. | 2020 | Details |
| A08634 | 32038102 | Int J Med Sci | Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2020 | Details |
| A08635 | 32037512 | Br J Pharmacol | P7C3-A20 alleviates fatty liver by shaping gut microbiota and inducing FGF21/FGF1, via the AMP-activated protein kinase/CREB regulated transcription coactivator 2 pathway. | 2020 | Details |
| A08645 | 32033765 | Gastroenterol Clin North Am | Nutrition and Nonalcoholic Fatty Liver Disease: Current Perspectives. | 2019 | Details |
| A08654 | 32033223 | Nutrients | Beneficial Effects of a Low-dose of Conjugated Linoleic Acid on Body Weight Gain and other Cardiometabolic Risk Factors in Cafeteria Diet-fed Rats. | 2020 | Details |
| A08655 | 32031871 | Am J Physiol Heart Circ Physiol | Gut microbiome of a porcine model of metabolic syndrome and HF-pEF. | 2020 | Details |
| A08656 | 32031683 | Hepatology | Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. | 2020 | Details |
| A08661 | 32029456 | Genes Dev | The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism. | 2020 | Details |
| A08665 | 32028458 | Med Sci Sports Exerc | Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD. | 2020 | Details |
| A08670 | 32027419 | J Gastroenterol Hepatol | Effects of constant light exposure on sphingolipidomics and progression of NASH in high-fat-fed rats. | 2020 | Details |
| A08672 | 32026851 | Med Sci Monit | The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid. | 2020 | Details |
| A08675 | 32025251 | J Med Life | Cellular Interactions in the Human Fatty Liver. | 2020 | Details |
| A08677 | 32025167 | J Clin Exp Hepatol | Extra-Hepatic Manifestations of Nonalcoholic Fatty Liver Disease: A Review. | 2019 | Details |
| A08681 | 32024509 | BMC Complement Med Ther | Structural modulation of gut microbiota during alleviation of non-alcoholic fatty liver disease with Gynostemma pentaphyllum in rats. | 2020 | Details |
| A08687 | 32021375 | J Inflamm Res | Saturated Fatty Acids in Obesity-Associated Inflammation. | 2020 | Details |
| A08688 | 32020961 | Med J Armed Forces India | The good, the bad, and the ugly facets of insulin resistance. | 2020 | Details |
| A08689 | 32020874 | BMC Complement Med Ther | Zhenqing recipe attenuates non-alcoholic fatty liver disease by regulating the SIK1/CRTC2 signaling in experimental diabetic rats. | 2020 | Details |
| A08691 | 32020770 | Pediatr Obes | Effect of the patatin-like phospholipase domain containing 3 gene (PNPLA3) I148M polymorphism on the risk and severity of nonalcoholic fatty liver disease and metabolic syndromes: A meta-analysis of paediatric and adolescent individuals. | 2020 | Details |
| A08692 | 32020523 | Biol Trace Elem Res | The Effect of Zinc Supplementation on Steatosis Severity and Liver Function Enzymes in Overweight/Obese Patients with Mild to Moderate Non-alcoholic Fatty Liver Following Calorie-Restricted Diet: a Double-Blind, Randomized Placebo-Controlled Trial. | 2020 | Details |
| A08693 | 32020371 | Curr Atheroscler Rep | Non-alcoholic Fatty Liver Disease and Its Links with Inflammation and Atherosclerosis. | 2020 | Details |
| A08699 | 32019315 | Rev Esp Enferm Dig | Metabolic syndrome, non-alcoholic fatty liver disease and hepatocarcinoma. | 2020 | Details |
| A08701 | 32017891 | Am J Med | Nonalcoholic Fatty Liver Disease: What Does the Primary Care Physician Need to Know? | 2020 | Details |
| A08703 | 32017594 | Am J Physiol Endocrinol Metab | Combined effect of canagliflozin and exercise training on high-fat diet-fed mice. | 2020 | Details |
| A08704 | 32017389 | Diabetes Metab Res Rev | Lower eGFR is associated with increased probability of liver fibrosis in Chinese diabetic patients. | 2020 | Details |
| A08710 | 32015930 | Liver Res | The acidic pathway of bile acid synthesis: Not just an alternative pathway☆. | 2019 | Details |
| A08716 | 32012908 | Cells | Unraveling LMNA Mutations in Metabolic Syndrome: Cellular Phenotype and Clinical Pitfalls. | 2020 | Details |
| A08725 | 32010935 | Biosci Rep | Letter to the Editor: Comments on "Obesity associated with a novel mitochondrial tRNACys m.5802A>G mutation in a Chinese family". | 2020 | Details |
| A08730 | 32008226 | Aging Clin Exp Res | Prognostic value of non-alcoholic fatty liver disease in the elderly patients. | 2020 | Details |
| A08742 | 32003680 | Curr Pharm Des | Dysmetabolic Hyperferritinemia and Dysmetabolic Iron Overload Syndrome (DIOS): Two Related Conditions or Different Entities? | 2020 | Details |
| A08745 | 32003601 | Am J Physiol Gastrointest Liver Physiol | Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH. | 2020 | Details |
| A08746 | 32002742 | Sleep Breath | Obstructive sleep apnea and liver injury in severely obese patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A08749 | 32001430 | Wiad Lek | Correction of adipocyte secretion disorders in patients with non-alcoholic fatty liver disease with overweight and obesity | 2019 | Details |
| A08751 | 32001301 | Biochim Biophys Acta Mol Basis Dis | Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver. | 2020 | Details |
| A08753 | 32000639 | Curr Pharm Des | Dysmetabolic Iron Overload in Metabolic Syndrome. | 2020 | Details |
| A08760 | 31998283 | Front Immunol | Absence of the Caspases 1/11 Modulates Liver Global Lipid Profile and Gut Microbiota in High-Fat-Diet-Induced Obese Mice. | 2020 | Details |
| A08773 | 31988879 | Pediatr Gastroenterol Hepatol Nutr | Factors associated with Advanced Bone Age in Overweight and Obese Children. | 2020 | Details |
| A08778 | 31987257 | Complement Ther Med | The effects of carnitine supplementation on clinical characteristics of patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2019 | Details |
| A08788 | 31984787 | Am J Physiol Gastrointest Liver Physiol | Vitamin D signaling maintains intestinal innate immunity and gut microbiota: potential intervention for metabolic syndrome and NAFLD. | 2020 | Details |
| A08793 | 31982140 | Biochem Biophys Res Commun | Targeting DUSP16/TAK1 signaling alleviates hepatic dyslipidemia and inflammation in high fat diet (HFD)-challenged mice through suppressing JNK MAPK. | 2020 | Details |
| A08822 | 31978277 | Mol Nutr Food Res | Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. | 2020 | Details |
| A08833 | 31972071 | Cell Physiol Biochem | Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model. | 2020 | Details |
| A08840 | 31969650 | Sci Rep | Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects. | 2020 | Details |
| A08847 | 31968197 | Endocr Pract | IMPACT OF TYPE 2 DIABETES ON NONALCOHOLIC STEATOHEPATITIS AND ADVANCED FIBROSIS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE. | 2020 | Details |
| A08850 | 31966908 | World J Hepatol | Lumacaftor/ivacaftor therapy is associated with reduced hepatic steatosis in cystic fibrosis patients. | 2019 | Details |
| A08855 | 31965018 | Sci Rep | Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice. | 2020 | Details |
| A08857 | 31963560 | Mar Drugs | Fucus vesiculosus and Ascophyllum nodosum Ameliorate Liver Function by Reducing Diet-Induced Steatosis in Rats. | 2020 | Details |
| A08860 | 31959914 | Cell Death Differ | Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. | 2020 | Details |
| A08864 | 31958476 | Diabetes Res Clin Pract | Fasting C-peptide is a significant indicator of nonalcoholic fatty liver disease in obese children. | 2020 | Details |
| A08871 | 31955626 | Endocr Res | Therapeutic Effects of SGLT2 Inhibitor Ipragliflozin and Metformin on NASH in Type 2 Diabetic Mice. | 2020 | Details |
| A08883 | 31953228 | Biochim Biophys Acta Mol Cell Biol Lipids | Effects of peptidoglycan on the development of steatohepatitis. | 2020 | Details |
| A08886 | 31952573 | Adv Clin Chem | Organokines in disease. | 2019 | Details |
| A08890 | 31950811 | Acta Gastroenterol Belg | Impact of liver inflammation on whole body insulin resistance : a case report on primary biliary cholangitis. | 2020 | Details |
| A08891 | 31950772 | Diabetes Metab J | Combination of Probiotics and Salvia miltiorrhiza Polysaccharide Alleviates Hepatic Steatosis via Gut Microbiota Modulation and Insulin Resistance Improvement in High Fat-Induced NAFLD Mice. | 2019 | Details |