Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A05096 | 33378048 | Eur Rev Med Pharmacol Sci | Gut microbiota and its metabolic potential. | 2020 | Details |
| A05102 | 33376110 | BMJ Open Gastroenterol | Prevalence, risk factors and metabolic profile of the non-obese and obese non-alcoholic fatty liver disease in a rural community of South Asia. | 2020 | Details |
| A05105 | 33374554 | Nutrients | Calorie-Restricted Mediterranean and Low-Fat Diets Affect Fatty Acid Status in Individuals with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05106 | 33374435 | J Clin Med | In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal. | 2020 | Details |
| A05107 | 33373666 | Diabetes Metab | Dose-response relationship between serum fibroblast growth factor 21 and liver fat content in non-alcoholic fatty liver disease. | 2020 | Details |
| A05112 | 33371482 | Biomolecules | Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants. | 2020 | Details |
| A05115 | 33370951 | BMJ Case Rep | Non-alcoholic steatohepatitis or autoimmune hepatitis? Sometimes a closer look under the surface is needed. | 2020 | Details |
| A05116 | 33370454 | J Gastroenterol Hepatol | Association between the severity of liver fibrosis and cardiovascular outcomes in patients with type 2 diabetes. | 2021 | Details |
| A05120 | 33368494 | J Clin Periodontol | Association between periodontitis and fibrotic progression of non-alcoholic fatty liver among Japanese adults. | 2021 | Details |
| A05122 | 33365151 | J Ultrason | Shear wave elastography reveals a high prevalence of liver fibrosis in overweight or obese Hispanic youth. | 2020 | Details |
| A05123 | 33364879 | Sisli Etfal Hastan Tip Bul | The Relationship between Insulin Resistance and Liver Damage in non-alcoholic Fatty Liver Patients. | 2020 | Details |
| A05124 | 33363621 | Oncol Lett | Biological effects of corosolic acid as an anti-inflammatory, anti-metabolic syndrome and anti-neoplasic natural compound. | 2020 | Details |
| A05126 | 33363258 | JGH Open | Association of metabolic-associated fatty liver disease and risk of severe coronavirus disease 2019 illness. | 2020 | Details |
| A05127 | 33363067 | Front Pediatr | New Perspectives on Genetic Prediction for Pediatric Metabolic Associated Fatty Liver Disease. | 2020 | Details |
| A05131 | 33362385 | World J Gastroenterol | Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats. | 2020 | Details |
| A05134 | 33360580 | Environ Pollut | Exposure to nitenpyram during pregnancy causes colonic mucosal damage and non-alcoholic steatohepatitis in mouse offspring: The role of gut microbiota. | 2020 | Details |
| A05136 | 33359683 | Free Radic Biol Med | ER stress-induced adipocytes secrete-aldo-keto reductase 1B7-containing exosomes that cause nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A05137 | 33359401 | Mol Metab | Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease. | 2020 | Details |
| A05138 | 33359400 | Mol Metab | Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH. | 2020 | Details |
| A05139 | 33358864 | Biochim Biophys Acta Gen Subj | GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH. | 2020 | Details |
| A05153 | 33352578 | Obes Facts | Hepatic Steatosis Is Associated with Elevated Serum Iron in Patients with Obesity and Improves after Laparoscopic Sleeve Gastrectomy. | 2020 | Details |
| A05154 | 33352441 | Int Immunopharmacol | Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses. | 2020 | Details |
| A05160 | 33349658 | Nat Rev Gastroenterol Hepatol | Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention. | 2020 | Details |
| A05162 | 33348700 | Nutrients | Nutritional Approaches for the Management of Nonalcoholic Fatty Liver Disease: An Evidence-Based Review. | 2020 | Details |
| A05163 | 33348647 | Children (Basel) | Antihistamines Increase Body Mass Index Percentiles and Z-Scores in Hispanic Children. | 2020 | Details |
| A05172 | 33346905 | Protein Cell | The role of the gut microbiome and its metabolites in metabolic diseases. | 2020 | Details |
| A05175 | 33346465 | Ter Arkh | [Non-alcoholic fatty liver disease and type 2 diabetes mellitus: issues of the liver fibrosis diagnostics]. | 2020 | Details |
| A05177 | 33346069 | Mol Metab | Metabolic drivers of non-alcoholic fatty liver disease. | 2020 | Details |
| A05184 | 33343673 | Evid Based Complement Alternat Med | Investigation of the Synergistic Effect of Brown Sugar, Longan, Ginger, and Jujube (Brown Sugar Longan Ginger Tea) on Antioxidation and Anti-Inflammation in In Vitro Models. | 2020 | Details |
| A05186 | 33343375 | Front Pharmacol | Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments. | 2020 | Details |
| A05193 | 33341026 | Phytomedicine | Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice. | 2020 | Details |
| A05194 | 33340925 | Thromb Res | Translational insight into prothrombotic state and hypercoagulation in nonalcoholic fatty liver disease. | 2020 | Details |
| A05204 | 33340186 | J Intern Med | Discrepancies between actual weight, weight perception and weight loss intention amongst persons with NAFLD. | 2020 | Details |
| A05212 | 33337101 | Compr Rev Food Sci Food Saf | Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues. | 2020 | Details |
| A05213 | 33336648 | Diabetes Metab Syndr | Nonalcoholic fatty liver disease should be considered for treatment allocation in standard management algorithms for type 2 diabetes. | 2020 | Details |
| A05215 | 33336025 | Open Med (Wars) | Effect of glucagon-like peptide-1 receptor agonists on adipokine level of nonalcoholic fatty liver disease in rats fed high-fat diet. | 2020 | Details |
| A05218 | 33334622 | Arch Med Res | Epidemiology, Pathogenesis, Diagnosis and Emerging Treatment of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05223 | 33333240 | Respir Physiol Neurobiol | Functional foods from the tropics to relieve chronic normobaric hypoxia. | 2020 | Details |
| A05226 | 33332766 | Immun Inflamm Dis | Inflammation initiates a vicious cycle between obesity and nonalcoholic fatty liver disease. | 2020 | Details |
| A05231 | 33330100 | Front Oncol | Etiology of Hepatocellular Carcinoma: Special Focus on Fatty Liver Disease. | 2020 | Details |
| A05237 | 33328206 | Diabetes | Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver. | 2020 | Details |
| A05240 | 33327438 | Int J Mol Sci | Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05247 | 33325808 | Am J Physiol Gastrointest Liver Physiol | Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A05249 | 33324348 | Front Endocrinol (Lausanne) | Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides. | 2020 | Details |
| A05251 | 33323806 | Chin Med J (Engl) | MAFLD vs. NAFLD: shared features and potential changes in epidemiology, pathophysiology, diagnosis, and pharmacotherapy. | 2020 | Details |
| A05270 | 33318479 | Cell Death Dis | Phosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner. | 2020 | Details |
| A05276 | 33317065 | Biomedicines | Dietary-Induced Low-Grade Inflammation in the Liver. | 2020 | Details |
| A05285 | 33312425 | World J Hepatol | Phase angle and non-alcoholic fatty liver disease before and after bariatric surgery. | 2020 | Details |
| A05286 | 33312424 | World J Hepatol | Cannabis use history is associated with increased prevalence of ascites among patients with nonalcoholic fatty liver disease: A nationwide analysis. | 2020 | Details |
| A05287 | 33312420 | World J Hepatol | Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo. | 2020 | Details |
| A05288 | 33311949 | World J Gastroenterol | Prevalence and predictors of nonalcoholic fatty liver disease in South Asian women with polycystic ovary syndrome. | 2020 | Details |
| A05294 | 33310034 | Life Sci | Aerobic training improves NAFLD markers and insulin resistance through AMPK-PPAR-α signaling in obese mice. | 2020 | Details |
| A05295 | 33309929 | J Proteomics | Proteome and phosphoproteome characterization of liver in the postprandial state from diet-induced obese and lean mice. | 2020 | Details |
| A05298 | 33309070 | Clin Investig Arterioscler | Approach to the cardiometabolic continuum. Narrative description. | 2020 | Details |
| A05299 | 33309037 | Am J Surg | The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests. | 2020 | Details |
| A05307 | 33307021 | Gastroenterology | AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review. | 2020 | Details |
| A05312 | 33305889 | Pediatr Obes | The relationship between excessive dietary fructose consumption and paediatric fatty liver disease. | 2020 | Details |
| A05315 | 33304627 | Curr Health Sci J | The Role of Elastography in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05316 | 33304027 | Toxicol Environ Chem | Per- and Polyfluoroalkyl Substances and Obesity, Type 2 Diabetes and Non-alcoholic Fatty Liver Disease: A Review of Epidemiologic Findings. | 2020 | Details |
| A05320 | 33303638 | Diabetes Care | High Prevalence of Advanced Liver Fibrosis Assessed by Transient Elastography Among U.S. Adults With Type 2 Diabetes. | 2020 | Details |
| A05321 | 33303564 | Gut | Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis. | 2020 | Details |
| A05322 | 33302841 | Curr Hypertens Rev | Nonalcoholic Fatty Liver Disease (NAFLD) for Primary Care Providers: Beyond the Liver. | 2021 | Details |
| A05325 | 33302598 | Int J Mol Sci | Understanding Mechanisms Underlying Non-Alcoholic Fatty Liver Disease (NAFLD) in Mental Illness: Risperidone and Olanzapine Alter the Hepatic Proteomic Signature in Mice. | 2020 | Details |
| A05326 | 33302316 | Horm Metab Res | Acute Elevated Resistin Exacerbates Mitochondrial Damage and Aggravates Liver Steatosis Through AMPK/PGC-1α Signaling Pathway in Male NAFLD Mice. | 2020 | Details |
| A05327 | 33301513 | PLoS One | RYGB increases postprandial gastric nesfatin-1 and rapid relieves NAFLD via gastric nerve detachment. | 2020 | Details |
| A05328 | 33301423 | J Clin Invest | Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223-enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis. | 2021 | Details |
| A05332 | 33299856 | Biomed Res Int | GCN2 Deficiency Enhances Protective Effects of Exercise on Hepatic Steatosis. | 2020 | Details |
| A05341 | 33296678 | Cell Metab | Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05342 | 33294831 | JHEP Rep | Macrophage-derived thrombospondin 1 promotes obesity-associated non-alcoholic fatty liver disease. | 2020 | Details |
| A05347 | 33291863 | Clin Mol Hepatol | The role of the gut microbiome and diet in the pathogenesis of non-alcoholic fatty liver disease. | 2020 | Details |
| A05348 | 33291552 | Children (Basel) | Glutamate-Serine-Glycine Index: A Novel Potential Biomarker in Pediatric Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05351 | 33290156 | Can J Physiol Pharmacol | Theobromine ameliorates nonalcoholic fatty liver disease by regulating hepatic lipid metabolism via mTOR signaling pathway in vivo and in vitro. | 2020 | Details |
| A05352 | 33289350 | Diabetes Obes Metab | Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: Results from two early-phase randomized trials. | 2020 | Details |
| A05356 | 33284184 | Am J Gastroenterol | Role of Noninvasive Tests in Clinical Gastroenterology Practices to Identify Patients With Nonalcoholic Steatohepatitis at High Risk of Adverse Outcomes: Expert Panel Recommendations. | 2021 | Details |
| A05372 | 33279947 | Eur J Clin Nutr | Lipid and saturated fatty acids intake and cardiovascular risk factors of obese children and adolescents. | 2020 | Details |
| A05375 | 33278596 | Biochim Biophys Acta Mol Cell Biol Lipids | Systems biology approaches to study lipidomes in health and disease. | 2020 | Details |
| A05379 | 33276220 | Adv Med Sci | Lack of change in serum sCD36 concentration in children with non-alcoholic fatty liver disease - A preliminary study. | 2020 | Details |
| A05384 | 33275326 | Diabetes Obes Metab | Extended-release naltrexone/bupropion and liver health: Pooled, post hoc analysis from four randomized controlled trials. | 2021 | Details |
| A05389 | 33273916 | Int J Endocrinol | Follicle-Stimulating Hormone Positively Associates with Metabolic Factors in Perimenopausal Women. | 2020 | Details |
| A05391 | 33273527 | Sci Rep | Deletion of the nuclear receptor RORα in macrophages does not modify the development of obesity, insulin resistance and NASH. | 2020 | Details |
| A05395 | 33271878 | Cells | Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using "Good-Fit" Genome-Editing Tools. | 2020 | Details |
| A05396 | 33271781 | Int J Mol Sci | Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05397 | 33271332 | Mol Metab | Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis. | 2020 | Details |
| A05400 | 33270482 | Expert Rev Gastroenterol Hepatol | A single-letter change in an acronym: signals, reasons, promises, challenges, and steps ahead for moving from NAFLD to MAFLD. | 2020 | Details |
| A05404 | 33269259 | World J Clin Cases | Essential phospholipids for nonalcoholic fatty liver disease associated with metabolic syndrome: A systematic review and network meta-analysis. | 2020 | Details |
| A05408 | 33268953 | World J Gastroenterol | Estimation of visceral fat is useful for the diagnosis of significant fibrosis in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A05409 | 33268944 | World J Gastroenterol | Nonalcoholic fatty liver disease in lean subjects: Prognosis, outcomes and management. | 2020 | Details |
| A05421 | 33264665 | J Nutr Biochem | Hepatic metabolic adaptation and adipose tissue expansion are altered in mice with steatohepatitis induced by high-fat high sucrose diet. | 2020 | Details |
| A05422 | 33263565 | J Endocrinol | Overexpression of the Lias gene attenuates hepatic steatosis in Leprdb/db mice. | 2021 | Details |
| A05428 | 33260451 | Int J Mol Sci | Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity. | 2020 | Details |
| A05432 | 33259744 | Metab Syndr Relat Disord | Triglyceride Glucose Index and Related Parameters (Triglyceride Glucose-Body Mass Index and Triglyceride Glucose-Waist Circumference) Identify Nonalcoholic Fatty Liver and Liver Fibrosis in Individuals with Overweight/Obesity. | 2020 | Details |
| A05441 | 33255949 | Biology (Basel) | Why Hepatic CYP2E1-Elevation by Itself Is Insufficient for Inciting NAFLD/NASH: Inferences from Two Genetic Knockout Mouse Models. | 2020 | Details |
| A05443 | 33255404 | Nutrients | POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver, and Insulin Resistance via Inhibitions of Pancreatic Lipase, cAMP-Dependent PDE Activity, AMPK Activation, and SOCS-3 Suppression. | 2020 | Details |
| A05450 | 33252713 | Protein Cell | Targeting the alternative bile acid synthetic pathway for metabolic diseases. | 2020 | Details |
| A05456 | 33250172 | J Pediatr | The Prevalence of Nonalcoholic Fatty Liver Disease and Its Risk Factors in Children and Young Adults with Type 1 Diabetes Mellitus. | 2020 | Details |
| A05459 | 33249617 | J Clin Lab Anal | Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity. | 2020 | Details |
| A05461 | 33248976 | Arab J Gastroenterol | Association of obesity and non-alcoholic fatty liver disease with the fecal calprotectin level in children. | 2020 | Details |
| A05462 | 33248947 | Arch Biochem Biophys | The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD. | 2020 | Details |
| A05463 | 33248441 | J Clin Endocrinol Metab | Insulin Resistance Is Central to Long-Term Reversal of Histologic Nonalcoholic Steatohepatitis After Metabolic Surgery. | 2021 | Details |
| A05464 | 33248170 | J Hepatol | Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores. | 2020 | Details |