Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A10210 | 31430977 | Int J Mol Sci | Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. | 2019 | Details |
| A10217 | 31428049 | Front Endocrinol (Lausanne) | The Liver in Children With Metabolic Syndrome. | 2019 | Details |
| A10218 | 31426291 | Int J Mol Sci | Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease. | 2019 | Details |
| A10220 | 31425956 | Diabetes Metab Syndr | A review of synbiotic efficacy in non-alcoholic fatty liver disease as a therapeutic approach. | 2019 | Details |
| A10223 | 31422074 | Arch Biochem Biophys | CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation. | 2019 | Details |
| A10233 | 31419514 | J Hepatol | Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development. | 2019 | Details |
| A10234 | 31419466 | Mol Cell Endocrinol | Empaglifozin mitigates NAFLD in high-fat-fed mice by alleviating insulin resistance, lipogenesis and ER stress. | 2019 | Details |
| A10235 | 31419414 | Clin Chim Acta | Fibroblast growth factor 21 in lipid metabolism and non-alcoholic fatty liver disease. | 2019 | Details |
| A10239 | 31417486 | Front Neurol | Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration. | 2019 | Details |
| A10240 | 31415794 | Mol Cell Endocrinol | Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A10248 | 31412686 | Genes (Basel) | Transcriptomic Analysis of Porcine Granulosa Cells Overexpressing Retinol Binding Protein 4. | 2019 | Details |
| A10249 | 31412267 | Eur J Pharmacol | Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways. | 2019 | Details |
| A10258 | 31408586 | Mol Nutr Food Res | Lycopene Alleviates Obesity-Induced Inflammation and Insulin Resistance by Regulating M1/M2 Status of Macrophages. | 2019 | Details |
| A10259 | 31408567 | Hepatol Res | Identification of two microRNA nodes as potential cooperative modulators of liver metabolism. | 2019 | Details |
| A10260 | 31408437 | J Clin Invest | Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis. | 2019 | Details |
| A10279 | 31401392 | Biomed Pharmacother | Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. | 2019 | Details |
| A10281 | 31401193 | EBioMedicine | Simulation of gastric bypass effects on glucose metabolism and non-alcoholic fatty liver disease with the Sleeveballoon device. | 2019 | Details |
| A10292 | 31397492 | Clin Exp Pharmacol Physiol | Insulin-like growth factor binding protein 7 accelerates hepatic steatosis and insulin resistance in non-alcoholic fatty liver disease. | 2019 | Details |
| A10293 | 31396538 | J Diabetes Res | Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes. | 2019 | Details |
| A10298 | 31393852 | JCI Insight | Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. | 2019 | Details |
| A10315 | 31389294 | Epigenetics | Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation. | 2019 | Details |
| A10316 | 31388695 | Diabetologia | Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis. | 2019 | Details |
| A10318 | 31388627 | Hepatol Commun | Associations Between Body Fat, Muscle Mass, and Nonalcoholic Fatty Liver Disease: A Population-Based Study. | 2019 | Details |
| A10322 | 31388398 | World J Hepatol | Rise of sodium-glucose cotransporter 2 inhibitors in the management of nonalcoholic fatty liver disease. | 2019 | Details |
| A10329 | 31387169 | Biomed Pharmacother | Mitochondrial dysfunction in high-fat diet-induced nonalcoholic fatty liver disease: The alleviating effect and its mechanism of Polygonatum kingianum. | 2019 | Details |
| A10332 | 31386565 | Am J Physiol Endocrinol Metab | Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice. | 2019 | Details |
| A10337 | 31384535 | Acta Pharm Sin B | Silibinin ameliorates hepatic lipid accumulation and oxidative stress in mice with non-alcoholic steatohepatitis by regulating CFLAR-JNK pathway. | 2019 | Details |
| A10338 | 31384531 | Acta Pharm Sin B | Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters. | 2019 | Details |
| A10339 | 31384519 | Biosci Microbiota Food Health | The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms. | 2019 | Details |
| A10341 | 31383290 | Tissue Cell | Azoramide ameliorates fructose-induced nonalcoholic fatty liver disease in mice. | 2019 | Details |
| A10343 | 31381969 | J Steroid Biochem Mol Biol | Understanding the association of polycystic ovary syndrome and non-alcoholic fatty liver disease. | 2019 | Details |
| A10360 | 31375010 | Int J Environ Res Public Health | Novel Insights into the Genetic Landscape of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10365 | 31373184 | J Korean Med Sci | Non-Alcoholic Fatty Liver Disease and Its Association with Depression in Korean General Population. | 2019 | Details |
| A10367 | 31372694 | Naunyn Schmiedebergs Arch Pharmacol | Chrysin ameliorates nonalcoholic fatty liver disease in rats. | 2019 | Details |
| A10369 | 31372020 | Diabetes Metab Syndr Obes | Abdominal subcutaneous fat thickness and homeostasis model assessment of insulin resistance as simple predictors of nonalcoholic steatohepatitis. | 2019 | Details |
| A10370 | 31371265 | Nutr Metab Cardiovasc Dis | Non-invasive assessment of hepatic lipid subspecies matched with non-alcoholic fatty liver disease phenotype. | 2019 | Details |
| A10377 | 31366455 | Gut | Epidemiology of chronic liver diseases in the USA in the past three decades. | 2019 | Details |
| A10379 | 31364723 | Int J Mol Med | Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats. | 2019 | Details |
| A10392 | 31357780 | Zhonghua Gan Zang Bing Za Zhi | [A new attempt with lipoprotein lipase agonists in the treatment of nonalcoholic steatohepatitis]. | 2019 | Details |
| A10400 | 31354322 | Diabetes Metab Syndr Obes | Obesity, adipocyte hypertrophy, fasting glucose, and resistin are potential contributors to nonalcoholic fatty liver disease in South Asian women. | 2019 | Details |
| A10401 | 31353974 | Expert Rev Gastroenterol Hepatol | Concurrent nonalcoholic fatty liver disease and type 2 diabetes: diagnostic and therapeutic considerations. | 2019 | Details |
| A10414 | 31345776 | Lancet Diabetes Endocrinol | Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study. | 2019 | Details |
| A10419 | 31343128 | Pediatr Endocrinol Diabetes Metab | Usefulness of the metabolic syndrome diagnosis in obese children in clinical practice. | 2019 | Details |
| A10421 | 31343010 | Food Funct | Oral α-lipoic acid supplementation in patients with non-alcoholic fatty liver disease: effects on adipokines and liver histology features. | 2019 | Details |
| A10425 | 31341532 | Oxid Med Cell Longev | Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance. | 2019 | Details |
| A10438 | 31336502 | Diabetes Metab Syndr | The influence of insulin resistance in the occurence of non-alcoholic fatty liver disease among first degree relatives of type 2 diabetes. | 2019 | Details |
| A10439 | 31336476 | Diabetes Metab Syndr | Nutrition and physical activity in Asian Indians with non-alcoholic fatty liver: A case control study. | 2019 | Details |
| A10440 | 31336445 | Diabetes Metab Syndr | Insulin resistance and hyperandrogenemia independently predict nonalcoholic fatty liver disease in women with polycystic ovary syndrome. | 2019 | Details |
| A10442 | 31336149 | Biochim Biophys Acta Mol Basis Dis | The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver. | 2019 | Details |
| A10446 | 31334442 | Hepatol Commun | Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes. | 2019 | Details |
| A10448 | 31333877 | Clin Diabetes Endocrinol | Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time. | 2019 | Details |
| A10465 | 31325638 | Biochim Biophys Acta Mol Cell Biol Lipids | Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH. | 2019 | Details |
| A10485 | 31316594 | Exp Ther Med | Effect of resveratrol on non-alcoholic fatty liver disease. | 2019 | Details |
| A10486 | 31315613 | BMC Endocr Disord | The relationship between non-alcoholic fatty liver and skeletal muscle mass to visceral fat area ratio in women with type 2 diabetes. | 2019 | Details |
| A10495 | 31311491 | BMC Gastroenterol | Low vitamin D level was associated with metabolic syndrome and high leptin level in subjects with nonalcoholic fatty liver disease: a community-based study. | 2019 | Details |
| A10507 | 31308717 | Diabetes Metab Syndr Obes | Liraglutide ameliorates nonalcoholic fatty liver disease in diabetic mice via the IRS2/PI3K/Akt signaling pathway. | 2019 | Details |
| A10508 | 31308716 | Diabetes Metab Syndr Obes | SGLT-2 inhibitors as promising therapeutics for non-alcoholic fatty liver disease: pathophysiology, clinical outcomes, and future directions. | 2019 | Details |
| A10511 | 31308382 | Sci Rep | Natural course of fatty liver in 36,195 South Korean adults. | 2019 | Details |
| A10519 | 31305201 | Metab Syndr Relat Disord | The Effect of Low Glycemic Index and Glycemic Load Diets on Hepatic Fat Mass, Insulin Resistance, and Blood Lipid Panels in Individuals with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10520 | 31304703 | J Assoc Physicians India | Association of Genetic Non-alcoholic Fatty Liver Disease with Insulin Resistance-Are we Different? | 2019 | Details |
| A10525 | 31301321 | J Hepatol | Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease. | 2019 | Details |
| A10526 | 31301251 | Clin Endocrinol (Oxf) | Clinical prediction score of nonalcoholic fatty liver disease in adolescent girls with polycystic ovary syndrome (PCOS-HS index). | 2019 | Details |
| A10535 | 31298151 | Curr Pharm Des | Obesity, Metabolic Syndrome and the Risk of Microvascular Complications in Patients with Diabetes mellitus. | 2019 | Details |
| A10540 | 31293912 | J Clin Transl Hepatol | Practical Use of Transient Elastography in Screening for Nonalcoholic Steatohepatitis in a Japanese Population. | 2019 | Details |
| A10545 | 31293441 | Front Physiol | The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH). | 2019 | Details |
| A10549 | 31293021 | Phytother Res | The effects of black seed supplementation on cardiovascular risk factors in patients with nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled clinical trial. | 2019 | Details |
| A10551 | 31292564 | Nat Rev Rheumatol | Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions. | 2019 | Details |
| A10570 | 31284753 | FASEB J | Hepatic PEMT activity mediates liver health, weight gain, and insulin resistance. | 2019 | Details |
| A10571 | 31284538 | Molecules | The Modulatory Action of Vitamin D on the Renin-Angiotensin System and the Determination of Hepatic Insulin Resistance. | 2019 | Details |
| A10580 | 31281460 | Exp Ther Med | Aged garlic extract ameliorates fatty liver and insulin resistance and improves the gut microbiota profile in a mouse model of insulin resistance. | 2019 | Details |
| A10588 | 31279902 | J Hepatol | The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis. | 2019 | Details |
| A10591 | 31278754 | J Physiol | Liver sympathetic denervation reverses obesity-induced hepatic steatosis. | 2019 | Details |
| A10599 | 31275421 | Evid Based Complement Alternat Med | The Combination of Mulberry Extracts and Silk Amino Acids Alleviated High Fat Diet-Induced Nonalcoholic Hepatic Steatosis by Improving Hepatic Insulin Signaling and Normalizing Gut Microbiome Dysbiosis in Rats. | 2019 | Details |
| A10601 | 31275407 | Evid Based Complement Alternat Med | Pharmacological Activities of Alisma orientale against Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: Literature Review. | 2019 | Details |
| A10614 | 31271251 | Mol Nutr Food Res | Diet Consisting of Balanced Yogurt, Fruit, and Vegetables Modifies the Gut Microbiota and Protects Mice against Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10624 | 31266632 | Biochem Biophys Res Commun | Expression of Vsig4 attenuates macrophage-mediated hepatic inflammation and fibrosis in high fat diet (HFD)-induced mice. | 2019 | Details |
| A10628 | 31264313 | Phytother Res | Hesperidin improves hepatic steatosis, hepatic enzymes, and metabolic and inflammatory parameters in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled, double-blind clinical trial. | 2019 | Details |
| A10642 | 31257745 | Endocrinol Metab (Seoul) | Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults. | 2019 | Details |
| A10651 | 31254236 | Clin Rheumatol | Metabolic syndrome, non-alcoholic fatty liver disease and liver stiffness in psoriatic arthritis and psoriasis patients. | 2019 | Details |
| A10664 | 31245932 | Obesity (Silver Spring) | Association Between Nonalcoholic Fatty Liver Disease and Future Deterioration of Metabolic Health: A Cohort Study. | 2019 | Details |
| A10670 | 31244307 | Asian Pac J Cancer Prev | Significance of Serum Adiponectin and Insulin Resistance Levels in Diagnosis of Egyptian Patients with Chronic Liver Disease and HCC. | 2019 | Details |
| A10672 | 31243652 | Endocrine | Insulin-like growth factor-1 and non-alcoholic fatty liver disease: a systemic review and meta-analysis. | 2019 | Details |
| A10684 | 31236937 | Australas J Dermatol | Nonalcoholic fatty liver disease puts patients with psoriasis at greater cardiovascular risk. | 2019 | Details |
| A10688 | 31235168 | Diabetes Metab Syndr | Efficacy of a non-invasive model in predicting the cardiovascular morbidity and histological severity in non-alcoholic fatty liver disease. | 2019 | Details |
| A10689 | 31235166 | Diabetes Metab Syndr | A narrative review on effects of vitamin D on main risk factors and severity of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10691 | 31235092 | Diabetes Metab Syndr | Study of relationship between total vitamin D level and NAFLD in a sample of Egyptian patients with and without T2DM. | 2019 | Details |
| A10695 | 31233775 | J Control Release | The hepatic-targeted, resveratrol loaded nanoparticles for relief of high fat diet-induced nonalcoholic fatty liver disease. | 2019 | Details |
| A10713 | 31226232 | Liver Int | Metabolically healthy versus unhealthy obesity and risk of fibrosis progression in non-alcoholic fatty liver disease. | 2019 | Details |
| A10717 | 31225483 | Cell Stress | Foie gras and liver regeneration: a fat dilemma. | 2018 | Details |
| A10719 | 31223344 | Diabetol Metab Syndr | Insulin resistance exhibits varied metabolic abnormalities in nonalcoholic fatty liver disease, chronic hepatitis B and the combination of the two: a cross-sectional study. | 2019 | Details |
| A10734 | 31216433 | J Ethnopharmacol | Exploring the protective effect of ShengMai-Yin and Ganmaidazao decoction combination against type 2 diabetes mellitus with nonalcoholic fatty liver disease by network pharmacology and validation in KKAy mice. | 2019 | Details |
| A10737 | 31215394 | Mol Med | FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease. | 2019 | Details |
| A10744 | 31213868 | Diabetes Metab Syndr Obes | The negative and detrimental effects of high fructose on the liver, with special reference to metabolic disorders. | 2019 | Details |
| A10761 | 31206703 | J Physiol | Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance. | 2019 | Details |
| A10763 | 31204416 | J Gastrointestin Liver Dis | Effect of Phytosomal Curcumin on Circulating Levels of Adiponectin and Leptin in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. | 2019 | Details |
| A10768 | 31203554 | Dig Dis Sci | Efficacy of Probiotics and Synbiotics in Patients with Nonalcoholic Fatty Liver Disease: A Meta-Analysis. | 2019 | Details |
| A10775 | 31197983 | J Korean Med Sci | Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A10777 | 31197470 | Acta Diabetol | Risk factors for non-alcoholic fatty liver disease-associated hepatic fibrosis in type 2 diabetes patients. | 2019 | Details |
| A10779 | 31197160 | Cell Death Dis | Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. | 2019 | Details |
| A10792 | 31191323 | Front Pharmacol | Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease. | 2019 | Details |