Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11930 | 30677224 | Mol Nutr Food Res | Beneficial Effects of Pomegranate on Lipid Metabolism in Metabolic Disorders. | 2019 | Details |
| A11932 | 30675881 | Food Funct | Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway. | 2019 | Details |
| A11937 | 30673851 | Med Mol Morphol | The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression. | 2019 | Details |
| A11940 | 30673619 | Cell Rep | Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. | 2019 | Details |
| A11947 | 30671129 | Evid Based Complement Alternat Med | Gegen Qinlian Decoction Attenuates High-Fat Diet-Induced Steatohepatitis in Rats via Gut Microbiota. | 2018 | Details |
| A11955 | 30669332 | Nutrients | Spirulina Liquid Extract Protects against Fibrosis Related to Non-Alcoholic Steatohepatitis and Increases Ursodeoxycholic Acid. | 2019 | Details |
| A11958 | 30668424 | Phytomedicine | Lycopus lucidus Turcz. ex Benth. Attenuates free fatty acid-induced steatosis in HepG2 cells and non-alcoholic fatty liver disease in high-fat diet-induced obese mice. | 2018 | Details |
| A11959 | 30668392 | Phytomedicine | Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor. | 2018 | Details |
| A11972 | 30661330 | J Exerc Nutrition Biochem | Hepatoprotective and anti-obesity effects of Korean blue honeysuckle extracts in high fat diet-fed mice. | 2018 | Details |
| A11973 | 30660906 | Chemosphere | Long-term bisphenol S exposure induces fat accumulation in liver of adult male zebrafish (Danio rerio) and slows yolk lipid consumption in F1 offspring. | 2019 | Details |
| A11978 | 30659956 | Exp Gerontol | Osthole inhibits oleic acid/lipopolysaccharide-induced lipid accumulation and inflammatory response through activating PPARα signaling pathway in cultured hepatocytes. | 2019 | Details |
| A11986 | 30658094 | Pharmacol Res | Intestinally derived bacterial products stimulate development of nonalcoholic steatohepatitis. | 2019 | Details |
| A11995 | 30653687 | Hepatology | Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Contributes to Hepatic Steatosis. | 2019 | Details |
| A11997 | 30653341 | Am J Physiol Gastrointest Liver Physiol | Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals. | 2019 | Details |
| A12000 | 30652641 | Curr Pharm Des | Nonalcoholic Fatty Liver Disease in Patients with Polycystic Ovary Syndrome. | 2018 | Details |
| A12014 | 30642871 | Dis Model Mech | Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity. | 2019 | Details |
| A12016 | 30642126 | Int J Mol Sci | Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A12030 | 30634538 | Molecules | MicroRNAs as a Novel Tool in the Diagnosis of Liver Lipid Dysregulation and Fatty Liver Disease. | 2019 | Details |
| A12036 | 30630736 | Dig Liver Dis | Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice. | 2018 | Details |
| A12053 | 30621707 | Lipids Health Dis | Plasma lipidomic signatures of spontaneous obese rhesus monkeys. | 2019 | Details |
| A12064 | 30618391 | Georgian Med News | [ANTHROPOMETRIC CHARACTERISTICS AND PARAMETERS OF LIPID-CARBOHYDRATE METABOLISM IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND HYPERTENSION DEPENDING ON THE DEGREE OF HEPATIC STEATOSIS]. | 2018 | Details |
| A12067 | 30617744 | Pflugers Arch | Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice. | 2019 | Details |
| A12069 | 30616587 | BMC Complement Altern Med | The traditional Chinese formulae Ling-gui-zhu-gan decoction alleviated non-alcoholic fatty liver disease via inhibiting PPP1R3C mediated molecules. | 2019 | Details |
| A12071 | 30615941 | Metab Eng | Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function. | 2019 | Details |
| A12076 | 30611993 | Biomed Pharmacother | Plumbagin reduces obesity and nonalcoholic fatty liver disease induced by fructose in rats through regulation of lipid metabolism, inflammation and oxidative stress. | 2019 | Details |
| A12077 | 30611723 | Toxicol Appl Pharmacol | Farnesol induces fatty acid oxidation and decreases triglyceride accumulation in steatotic HepaRG cells. | 2019 | Details |
| A12078 | 30611703 | Alcohol | Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue. | 2019 | Details |
| A12080 | 30611282 | Lipids Health Dis | Concurrent exercise improves insulin resistance and nonalcoholic fatty liver disease by upregulating PPAR-γ and genes involved in the beta-oxidation of fatty acids in ApoE-KO mice fed a high-fat diet. | 2019 | Details |
| A12083 | 30609663 | Cells | Relevance of Autophagy in Parenchymal and Non-Parenchymal Liver Cells for Health and Disease. | 2019 | Details |
| A12091 | 30605949 | Zhonghua Nei Ke Za Zhi | [Glucagon-like peptide-1 regulates lipid metabolism in hepatocytes through Foxo1/3]. | 2019 | Details |
| A12093 | 30605818 | Environ Pollut | Effects of triphenyl phosphate exposure during fetal development on obesity and metabolic dysfunctions in adult mice: Impaired lipid metabolism and intestinal dysbiosis. | 2018 | Details |
| A12094 | 30605676 | Cell Rep | Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. | 2019 | Details |
| A12096 | 30604460 | Diabetes Metab Res Rev | Angiotensin-converting enzyme 2 inhibits endoplasmic reticulum stress-associated pathway to preserve nonalcoholic fatty liver disease. | 2019 | Details |
| A12098 | 30603757 | Mol Omics | Gene expression profile-based drug screen identifies SAHA as a novel treatment for NAFLD. | 2019 | Details |
| A12126 | 30591521 | EMBO Mol Med | The role of the microbiome in NAFLD and NASH. | 2019 | Details |
| A12133 | 30589487 | Obes Rev | Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome. | 2018 | Details |
| A12135 | 30588564 | Drugs | Current and Emerging Therapies for Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A12143 | 30583863 | Biochem Biophys Res Commun | Erythropoietin and long-acting erythropoiesis stimulating agent ameliorate non-alcoholic fatty liver disease by increasing lipolysis and decreasing lipogenesis via EPOR/STAT pathway. | 2018 | Details |
| A12147 | 30582764 | Hepatology | Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. | 2019 | Details |
| A12150 | 30581002 | Biochem Biophys Res Commun | Secreted modular calcium-binding protein 2 promotes high fat diet (HFD)-induced hepatic steatosis through enhancing lipid deposition, fibrosis and inflammation via targeting TGF-β1. | 2018 | Details |
| A12156 | 30578967 | Biochim Biophys Acta Mol Cell Biol Lipids | Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. | 2018 | Details |
| A12157 | 30578708 | Mol Nutr Food Res | Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro. | 2019 | Details |
| A12162 | 30577497 | Int J Mol Sci | Olive Oil, Palm Oil, and Hybrid Palm Oil Distinctly Modulate Liver Transcriptome and Induce NAFLD in Mice Fed a High-Fat Diet. | 2018 | Details |
| A12171 | 30576244 | Am J Physiol Endocrinol Metab | Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments. | 2018 | Details |
| A12174 | 30574460 | Eur Thyroid J | Association between Thyroid-Stimulating Hormone Levels and Non-Alcoholic Fatty Liver Disease Is Not Independent from Metabolic Syndrome Criteria. | 2018 | Details |
| A12181 | 30573200 | Arch Med Res | Roles of Autophagy and Protein Kinase C-epsilon in Lipid Metabolism of Nonalcoholic Fatty Liver Cell Models. | 2018 | Details |
| A12182 | 30572788 | Biosci Biotechnol Biochem | A review of the studies on food-derived factors which regulate energy metabolism via the modulation of lipid-sensing nuclear receptors. | 2018 | Details |
| A12183 | 30572631 | Int J Mol Sci | Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model. | 2018 | Details |
| A12192 | 30568000 | Biochem J | ZNF300 stimulates fatty acid oxidation and alleviates hepatosteatosis through regulating PPARα. | 2019 | Details |
| A12218 | 30558790 | Biochem Biophys Res Commun | Upregulation of miR-181a impairs lipid metabolism by targeting PPARα expression in nonalcoholic fatty liver disease. | 2018 | Details |
| A12228 | 30555521 | Nutr Metab (Lond) | Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice. | 2018 | Details |
| A12235 | 30553055 | Biochim Biophys Acta Mol Cell Biol Lipids | Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease. | 2018 | Details |
| A12239 | 30551393 | Biomed Pharmacother | Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats. | 2018 | Details |
| A12240 | 30551380 | Biomed Pharmacother | Preventive effect of trans-chalcone on non-alcoholic steatohepatitis: Improvement of hepatic lipid metabolism. | 2018 | Details |
| A12259 | 30543441 | Mol Pharm | Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice. | 2018 | Details |
| A12266 | 30541128 | J Clin Endocrinol Metab | The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet. | 2019 | Details |
| A12274 | 30538803 | Oxid Med Cell Longev | Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet-Induced Accumulation of Lipid in the Liver of ApoE-/- Mice. | 2018 | Details |
| A12279 | 30536914 | J Physiol | Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions. | 2019 | Details |
| A12285 | 30533179 | World J Hepatol | Treating nonalcoholic steatohepatitis with antidiabetic drugs: Will GLP-1 agonists end the struggle? | 2018 | Details |
| A12302 | 30518830 | Nat Rev Gastroenterol Hepatol | Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators. | 2019 | Details |
| A12318 | 30516830 | Hepatology | Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages. | 2019 | Details |
| A12329 | 30513881 | Nutrients | Apple Pomace Consumption Favorably Alters Hepatic Lipid Metabolism in Young Female Sprague-Dawley Rats Fed a Western Diet. | 2018 | Details |
| A12362 | 30484323 | Antioxid Redox Signal | Isosteviol Protects Free Fatty Acid- and High Fat Diet-Induced Hepatic Injury via Modulating PKC-β/p66Shc/ROS and Endoplasmic Reticulum Stress Pathways. | 2019 | Details |
| A12363 | 30484310 | J Agric Food Chem | Folic Acid Reduced Triglycerides Deposition in Primary Chicken Hepatocytes. | 2018 | Details |
| A12374 | 30482436 | J Pharmacol Sci | Lipid-modulate activity of Cichorium glandulosum Boiss. et Huet polysaccharide in nonalcoholic fatty liver disease larval zebrafish model. | 2018 | Details |
| A12390 | 30473057 | Metabolism | Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models. | 2018 | Details |
| A12391 | 30473026 | Life Sci | p53 as a double-edged sword in the progression of non-alcoholic fatty liver disease. | 2018 | Details |
| A12398 | 30472196 | Diabetes Metab | Low N-terminal pro-brain natriuretic peptide levels are associated with non-alcoholic fatty liver disease in patients with type 2 diabetes. | 2018 | Details |
| A12405 | 30469030 | Redox Biol | Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes. | 2018 | Details |
| A12414 | 30465824 | Free Radic Biol Med | Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia. | 2018 | Details |
| A12425 | 30458883 | J Transl Med | Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway. | 2018 | Details |
| A12431 | 30457913 | Am J Physiol Endocrinol Metab | Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity. | 2018 | Details |
| A12434 | 30456918 | Diabetes Obes Metab | Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis? | 2018 | Details |
| A12435 | 30455723 | Nutr Metab (Lond) | Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults. | 2018 | Details |
| A12439 | 30455063 | Adv Biol Regul | Alcoholic and non-alcoholic fatty liver disease: Focus on ceramide. | 2018 | Details |
| A12446 | 30453990 | J Transl Med | Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. | 2018 | Details |
| A12456 | 30447138 | Mol Nutr Food Res | Malprogramming of Hepatic Lipid Metabolism due to Excessive Early Cholesterol Exposure in Adult Progeny. | 2018 | Details |
| A12459 | 30446669 | Nat Commun | Serotonin signals through a gut-liver axis to regulate hepatic steatosis. | 2018 | Details |
| A12496 | 30422676 | Am J Respir Crit Care Med | Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12497 | 30421529 | Lipids | Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese. | 2018 | Details |
| A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |
| A12509 | 30415113 | Chemosphere | Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction. | 2018 | Details |
| A12512 | 30414175 | J Sci Food Agric | Triticum aestivum ethanolic extract improves non-alcoholic fatty liver disease in mice fed a choline-deficient or high-fat diet. | 2019 | Details |
| A12513 | 30413815 | Lab Invest | Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero. | 2018 | Details |
| A12523 | 30411231 | J Physiol Biochem | Lipid metabolism in adipose tissue and liver from diet-induced obese rats: a comparison between Wistar and Sprague-Dawley strains. | 2018 | Details |
| A12530 | 30408433 | Toxicol Appl Pharmacol | 6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. | 2018 | Details |
| A12531 | 30408316 | Mol Nutr Food Res | Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver. | 2018 | Details |
| A12533 | 30405551 | Front Microbiol | Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice. | 2018 | Details |
| A12539 | 30402207 | Oxid Med Cell Longev | miR-26a Potentially Contributes to the Regulation of Fatty Acid and Sterol Metabolism In Vitro Human HepG2 Cell Model of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12541 | 30401637 | Cancer Lett | Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1α. | 2018 | Details |
| A12545 | 30400243 | Molecules | Stable Isotope-Labeled Lipidomics to Unravel the Heterogeneous Development Lipotoxicity. | 2018 | Details |
| A12546 | 30400205 | Int J Mol Sci | Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression. | 2018 | Details |
| A12564 | 30389231 | Cytokine | Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression. | 2018 | Details |
| A12566 | 30388740 | Nutrients | Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism. | 2018 | Details |
| A12575 | 30383414 | Am J Physiol Gastrointest Liver Physiol | Lipid mediators of liver injury in nonalcoholic fatty liver disease. | 2018 | Details |
| A12578 | 30380656 | Nutrients | Advanced Liver Fibrosis Is Independently Associated with Palmitic Acid and Insulin Levels in Patients with Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A12589 | 30374109 | Sci Rep | Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism. | 2018 | Details |
| A12599 | 30368556 | Eur J Nutr | Differential capability of metabolic substrates to promote hepatocellular lipid accumulation. | 2018 | Details |
| A12600 | 30368219 | Phytochemistry | Flavone glycosides from Sicyos angulatus and their inhibitory effects on hepatic lipid accumulation. | 2018 | Details |
| A12606 | 30366981 | Mol Pharmacol | Cilostazol Improves HFD-Induced Hepatic Steatosis by Upregulating Hepatic STAMP2 Expression through AMPK. | 2018 | Details |