Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09288 | 31805015 | J Clin Invest | Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease. | 2020 | Details |
| A09292 | 31803542 | PeerJ | Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice. | 2019 | Details |
| A09293 | 31803485 | BMJ Open Diabetes Res Care | Determinants of longitudinal change in insulin clearance: the Prospective Metabolism and Islet Cell Evaluation cohort. | 2019 | Details |
| A09294 | 31803464 | Ther Adv Endocrinol Metab | Reduced physical activity in young and older adults: metabolic and musculoskeletal implications. | 2019 | Details |
| A09296 | 31801616 | J Transl Med | Microbiota, type 2 diabetes and non-alcoholic fatty liver disease: protocol of an observational study. | 2019 | Details |
| A09300 | 31800592 | PLoS One | Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis. | 2019 | Details |
| A09306 | 31797544 | Mol Nutr Food Res | Vitamin D Deficiency Induces Insulin Resistance and Re-Supplementation Attenuates Hepatic Glucose Output via the PI3K-AKT-FOXO1 Mediated Pathway. | 2020 | Details |
| A09308 | 31796953 | Am J Clin Nutr | Metabolic effects of a prolonged, very-high-dose dietary fructose challenge in healthy subjects. | 2020 | Details |
| A09310 | 31795988 | BMC Public Health | First-degree family history of diabetes and its relationship with serum osteocalcin levels independent of liver fat content in a non-diabetic Chinese cohort. | 2019 | Details |
| A09312 | 31795496 | Cells | Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins. | 2019 | Details |
| A09322 | 31790897 | Phytomedicine | Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates insulin resistance and hepatic steatosis via PI3K/Akt/GSK3β pathway. | 2019 | Details |
| A09324 | 31790829 | Free Radic Biol Med | Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice. | 2019 | Details |
| A09329 | 31789677 | Curr Opin Lipidol | Fatty liver, cardiometabolic disease and mortality. | 2020 | Details |
| A09335 | 31786361 | Diabetes Metab | Screening for non-alcoholic fatty liver disease using liver stiffness measurement and its association with chronic kidney disease and cardiovascular complications in patients with type 2 diabetes. | 2019 | Details |
| A09345 | 31783635 | Nutrients | Circulating miRNAs as Biomarkers of Obesity and Obesity-Associated Comorbidities in Children and Adolescents: A Systematic Review. | 2019 | Details |
| A09349 | 31782258 | Physiol Rep | SGLT2 inhibitor ipragliflozin alone and combined with pioglitazone prevents progression of nonalcoholic steatohepatitis in a type 2 diabetes rodent model. | 2019 | Details |
| A09354 | 31781248 | Stem Cells Int | Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice. | 2019 | Details |
| A09356 | 31780766 | Sci Rep | Sodium fluorocitrate having inhibitory effect on fatty acid uptake ameliorates high fat diet-induced non-alcoholic fatty liver disease in C57BL/6J mice. | 2019 | Details |
| A09358 | 31779730 | Br J Nutr | Dietary protein insufficiency: an important consideration in fatty liver disease? | 2019 | Details |
| A09361 | 31777896 | Food Funct | Attenuation of metabolic syndrome in the ob/ob mouse model by resistant starch intervention is dose dependent. | 2019 | Details |
| A09369 | 31775341 | Int J Mol Sci | Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction. | 2019 | Details |
| A09373 | 31771682 | Br J Nutr | Crude extract of Camellia oleifera pomace ameliorates the progression of non-alcoholic fatty liver disease via decreasing fat accumulation, insulin resistance and inflammation. | 2019 | Details |
| A09381 | 31769484 | Clin Sci (Lond) | Dapagliflozin not only improves hepatic injury and pancreatic endoplasmic reticulum stress, but also induces hepatic gluconeogenic enzymes expression in obese rats. | 2019 | Details |
| A09383 | 31767938 | Sci Rep | Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease. | 2019 | Details |
| A09384 | 31767252 | Presse Med | [Pathogenesis of non-alcoholic fatty liver disease]. | 2019 | Details |
| A09386 | 31766373 | J Clin Med | Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review. | 2019 | Details |
| A09387 | 31765666 | Metabolism | Low levels of total and high-molecular-weight adiponectin may predict non-alcoholic fatty liver in Korean adults. | 2019 | Details |
| A09393 | 31762148 | Liver Int | Dietary fatty acid oxidation is decreased in non-alcoholic fatty liver disease: A palmitate breath test study. | 2019 | Details |
| A09397 | 31760464 | Cell Mol Life Sci | Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis. | 2020 | Details |
| A09399 | 31760308 | J Nutr Biochem | Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice. | 2019 | Details |
| A09401 | 31759197 | J Nutr Biochem | Mitigation of nonalcoholic fatty liver disease in high-fat-fed mice by the combination of decaffeinated green tea extract and voluntary exercise. | 2019 | Details |
| A09402 | 31759125 | Peptides | The influence of Glucose-dependent Insulinotropic Polypeptide (GIP) on human adipose tissue and fat metabolism: Implications for obesity, type 2 diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD). | 2019 | Details |
| A09405 | 31758951 | Metabolism | Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. | 2019 | Details |
| A09415 | 31757735 | Presse Med | [Pharmacological treatment of NASH]. | 2019 | Details |
| A09417 | 31757727 | Presse Med | [Nutritional Management of Nonalcoholic fatty liver disease (NAFLD)]. | 2019 | Details |
| A09425 | 31754954 | Hormones (Athens) | Obese boys with low concentrations of high-density lipoprotein cholesterol are at greater risk of hepatosteatosis. | 2019 | Details |
| A09428 | 31754142 | Sci Rep | New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery. | 2019 | Details |
| A09439 | 31749893 | Diabetol Metab Syndr | Long-term treatment with metformin in the prevention of fatty liver in Zucker diabetic fatty rats. | 2019 | Details |
| A09442 | 31748681 | Lab Invest | Maternal diet intervention before pregnancy primes offspring lipid metabolism in liver. | 2019 | Details |
| A09444 | 31746482 | Aliment Pharmacol Ther | Systematic review: chronic viral hepatitis and metabolic derangement. | 2019 | Details |
| A09447 | 31745030 | Indian J Med Microbiol | Gut microbiota and its mysteries. | 2020 | Details |
| A09460 | 31737175 | Oxid Med Cell Longev | Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients. | 2019 | Details |
| A09463 | 31734856 | Intern Emerg Med | Liver alterations in anorexia nervosa are not caused by insulin resistance. | 2019 | Details |
| A09474 | 31730978 | Int J Biol Macromol | Resistant starch from green banana (Musa sp.) attenuates non-alcoholic fat liver accumulation and increases short-chain fatty acids production in high-fat diet-induced obesity in mice. | 2019 | Details |
| A09505 | 31717414 | Int J Mol Sci | Lipid Related Genes Altered in NASH Connect Inflammation in Liver Pathogenesis Progression to HCC: A Canonical Pathway. | 2019 | Details |
| A09508 | 31717271 | J Clin Med | The Association between SOCS1-1656G>A Polymorphism, Insulin Resistance and Obesity in Nonalcoholic Fatty Liver Disease (NAFLD) Patients. | 2019 | Details |
| A09514 | 31714387 | Eur J Gastroenterol Hepatol | Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome. | 2020 | Details |
| A09535 | 31705444 | Hepatol Int | Sarcopenia and fatty liver disease. | 2019 | Details |
| A09538 | 31703079 | PLoS One | Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation. | 2019 | Details |
| A09539 | 31702809 | Mol Med Rep | Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet. | 2019 | Details |
| A09548 | 31697972 | J Hepatol | Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study. | 2019 | Details |
| A09549 | 31697646 | Aging (Albany NY) | Catalpol induces autophagy and attenuates liver steatosis in ob/ob and high-fat diet-induced obese mice. | 2019 | Details |
| A09557 | 31695251 | J Clin Exp Hepatol | Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A09567 | 31692530 | Pediatric Health Med Ther | Pediatric non-alcoholic fatty liver disease: current perspectives on diagnosis and management. | 2019 | Details |
| A09568 | 31692390 | Expert Rev Gastroenterol Hepatol | Progress in promising anti-fibrotic therapies. | 2019 | Details |
| A09569 | 31692226 | Diabetes Obes Metab | Exenatide and dapagliflozin combination improves markers of liver steatosis and fibrosis in patients with type 2 diabetes. | 2019 | Details |
| A09573 | 31690988 | Diabetologia | Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation. | 2019 | Details |
| A09574 | 31690932 | J Clin Endocrinol Metab | Targeted Analysis of Three Hormonal Systems Identifies Molecules Associated with the Presence and Severity of NAFLD. | 2020 | Details |
| A09575 | 31689910 | Nutrients | The Role of Probiotics in Nonalcoholic Fatty Liver Disease: A New Insight into Therapeutic Strategies. | 2019 | Details |
| A09581 | 31688305 | Eur J Gastroenterol Hepatol | Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09582 | 31687367 | Can J Gastroenterol Hepatol | The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. | 2019 | Details |
| A09583 | 31686884 | Diabetes Metab Syndr Obes | Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors: A Clinician's Guide. | 2019 | Details |
| A09585 | 31686320 | Sci China Life Sci | Regulation of glucose and lipid metabolism in health and disease. | 2019 | Details |
| A09587 | 31685793 | Nutr Diabetes | Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements. | 2019 | Details |
| A09588 | 31685037 | Br J Nutr | Whole-grain consumption and its effects on hepatic steatosis and liver enzymes in patients with non-alcoholic fatty liver disease: a randomised controlled clinical trial. | 2019 | Details |
| A09600 | 31679693 | Biochem Biophys Res Commun | Identification of isotschimgine as a novel farnesoid X receptor agonist with potency for the treatment of obesity in mice. | 2019 | Details |
| A09604 | 31677889 | Nutr Metab Cardiovasc Dis | Insulin resistance, but not insulin response, during oral glucose tolerance test (OGTT) is associated to worse histological outcome in obese NAFLD. | 2019 | Details |
| A09612 | 31675274 | Metab Syndr Relat Disord | Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection. | 2019 | Details |
| A09619 | 31672578 | Life Sci | Amlexanox reversed non-alcoholic fatty liver disease through IKKε inhibition of hepatic stellate cell. | 2019 | Details |
| A09620 | 31672448 | Metabolism | Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box! | 2019 | Details |
| A09622 | 31671785 | Nutrients | mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance. | 2019 | Details |
| A09628 | 31669275 | Int J Biol Macromol | Codonopsis lanceolata polysaccharide CLPS alleviates high fat/high sucrose diet-induced insulin resistance via anti-oxidative stress. | 2019 | Details |
| A09635 | 31668088 | Int J Environ Health Res | Evaluation of sucrose-enriched diet consumption in the development of risk factors associated to type 2 diabetes, atherosclerosis and non-alcoholic fatty liver disease in a murine model. | 2019 | Details |
| A09648 | 31659239 | Acta Pharmacol Sin | Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway. | 2019 | Details |
| A09649 | 31659105 | Cancer Genomics Proteomics | Synergism of Adipocytokine Profile and ADIPOQ/TNF-α Polymorphisms in NAFLD-associated MetS Predict Colorectal Liver Metastases Outgrowth. | 2020 | Details |
| A09661 | 31655133 | J Hepatol | β-Klotho gene variation is associated with liver damage in children with NAFLD. | 2019 | Details |
| A09668 | 31652837 | Cancers (Basel) | Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer. | 2019 | Details |
| A09681 | 31650383 | Mol Biol Rep | High fructose-containing drinking water-induced steatohepatitis in rats is prevented by the nicotinamide-mediated modulation of redox homeostasis and NADPH-producing enzymes. | 2019 | Details |
| A09686 | 31648561 | FASEB J | KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-κB-FGF21 or SREBP1c-FGF21 pathway. | 2019 | Details |
| A09698 | 31641351 | Int J Endocrinol | RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09709 | 31637670 | Obes Surg | What Is the Role of the New Index Relative Fat Mass (RFM) in the Assessment of Nonalcoholic Fatty Liver Disease (NAFLD)? | 2020 | Details |
| A09710 | 31637346 | J Endocr Soc | Nonalcoholic Fatty Liver Disease in Nonobese Subjects of African Origin Has Atypical Metabolic Characteristics. | 2019 | Details |
| A09711 | 31637181 | J Transl Int Med | Effect of Weight Reduction on Histological Activity and Fibrosis of Lean Nonalcoholic Steatohepatitis Patient. | 2019 | Details |
| A09722 | 31634046 | J Med Food | Oral Administration of Hoodia parviflora Alleviates Insulin Resistance and Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09723 | 31633724 | Arq Gastroenterol | A STUDY OF METABOLIC PARAMETERS IN NON DIABETIC PATIENTS WITH NON ALCOHOLIC FATTY LIVER DISEASE - IMPORTANCE OF DYSLIPIDEMIA. | 2019 | Details |
| A09734 | 31632109 | Diabetes Metab Syndr Obes | Plant-derived oleanolic acid ameliorates markers associated with non-alcoholic fatty liver disease in a diet-induced pre-diabetes rat model. | 2019 | Details |
| A09736 | 31631098 | Endocr J | Regulation of angiopoietin-like protein 8 expression under different nutritional and metabolic status. | 2019 | Details |
| A09738 | 31630897 | Trends Endocrinol Metab | NAFLD and Atherosclerosis: Two Sides of the Same Dysmetabolic Coin? | 2019 | Details |
| A09740 | 31630414 | Hepatology | Fatty Acid Synthase Inhibitor TVB-2640 Reduces Hepatic de Novo Lipogenesis in Males With Metabolic Abnormalities. | 2020 | Details |
| A09742 | 31629472 | Biochem Biophys Res Commun | MC4R deficiency in pigs results in hyperphagia and ultimately hepatic steatosis without high-fat diet. | 2019 | Details |
| A09744 | 31628998 | Clin Gastroenterol Hepatol | Decreased Physical Working Capacity in Adolescents With Nonalcoholic Fatty Liver Disease Associates With Reduced Iron Availability. | 2019 | Details |
| A09751 | 31625959 | Eur J Gastroenterol Hepatol | Homeostatic model assessment of insulin resistance closely related to lobular inflammation in nonalcoholic fatty liver disease. | 2020 | Details |
| A09758 | 31622581 | Am J Med | Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09759 | 31622202 | Curr Drug Deliv | Protective Effects of Incretin Against Age-Related Diseases. | 2019 | Details |
| A09762 | 31620647 | Transl Gastroenterol Hepatol | Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations. | 2019 | Details |
| A09763 | 31620616 | Yeungnam Univ J Med | Pharmacologic therapy for nonalcoholic steatohepatitis focusing on pathophysiology. | 2019 | Details |
| A09771 | 31616384 | Front Endocrinol (Lausanne) | Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09798 | 31606352 | Ann Hepatol | Chronic kidney disease in patients with non-alcoholic fatty liver disease: What the Hepatologist should know? | 2019 | Details |
| A09800 | 31604965 | Sci Rep | Depletion of CD40 on CD11c+ cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. | 2019 | Details |
| A09801 | 31604805 | J Lipid Res | Angiotensinogen in hepatocytes contributes to Western diet-induced liver steatosis. | 2019 | Details |