Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Bone522 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08773 | 31988879 | Pediatr Gastroenterol Hepatol Nutr | Factors associated with Advanced Bone Age in Overweight and Obese Children. | 2020 | Details |
| A08900 | 31948295 | Expert Opin Investig Drugs | Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)? | 2020 | Details |
| A09039 | 31894013 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | [Review of macrophage heterogeneity and progression of nonalcoholic fatty liver disease]. | 2019 | Details |
| A09135 | 31861914 | Cells | Oncostatin M, A Profibrogenic Mediator Overexpressed in Non-Alcoholic Fatty Liver Disease, Stimulates Migration of Hepatic Myofibroblasts. | 2019 | Details |
| A09172 | 31849997 | Front Immunol | Therapeutic Targeting of Hepatic Macrophages for the Treatment of Liver Diseases. | 2019 | Details |
| A09223 | 31831718 | Aging (Albany NY) | Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. | 2019 | Details |
| A09380 | 31770104 | Eur J Endocrinol | Increased risk of low bone mineral density in patients with non-alcoholic fatty liver disease: a cohort study. | 2020 | Details |
| A09386 | 31766373 | J Clin Med | Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review. | 2019 | Details |
| A09548 | 31697972 | J Hepatol | Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study. | 2019 | Details |
| A09583 | 31686884 | Diabetes Metab Syndr Obes | Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors: A Clinician's Guide. | 2019 | Details |
| A09648 | 31659239 | Acta Pharmacol Sin | Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway. | 2019 | Details |
| A09669 | 31652761 | Nutrients | Obesity in the Liver Transplant Setting. | 2019 | Details |
| A09766 | 31618976 | Int J Mol Sci | The Potential of the FSP1cre-Pparb/d-/- Mouse Model for Studying Juvenile NAFLD. | 2019 | Details |
| A09866 | 31584360 | Curr Med Chem | Stem Cell Transplant for Advanced Stage Liver Disorders: Current Scenario and Future Prospects. | 2020 | Details |
| A09976 | 31538528 | Future Med Chem | Extra-hepatic manifestations and complications of nonalcoholic fatty liver disease. | 2019 | Details |
| A10399 | 31354839 | Stem Cells Int | Kupffer Cells Promote the Differentiation of Adult Liver Hematopoietic Stem and Progenitor Cells into Lymphocytes via ICAM-1 and LFA-1 Interaction. | 2019 | Details |
| A10474 | 31322255 | Mol Med Rep | Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice. | 2019 | Details |
| A10565 | 31288993 | Mol Metab | GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury. | 2019 | Details |
| A10624 | 31266632 | Biochem Biophys Res Commun | Expression of Vsig4 attenuates macrophage-mediated hepatic inflammation and fibrosis in high fat diet (HFD)-induced mice. | 2019 | Details |
| A10746 | 31213030 | J Clin Med | A Systematic Review of NAFLD-Associated Extrahepatic Disorders in Youths. | 2019 | Details |
| A10974 | 31096638 | Cells | Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro. | 2019 | Details |
| A11032 | 31076404 | Gut | Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis. | 2019 | Details |
| A11037 | 31074909 | J Bone Miner Res | Nonalcoholic Fatty Liver Disease in The Rotterdam Study: About Muscle Mass, Sarcopenia, Fat Mass, and Fat Distribution. | 2019 | Details |
| A11070 | 31060228 | Biomolecules | Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague⁻Dawley Rats †. | 2019 | Details |
| A11098 | 31043271 | Biochem Biophys Res Commun | Hepatocellular iNOS protects liver from NASH through Nrf2-dependent activation of HO-1. | 2019 | Details |
| A11239 | 30978348 | Life Sci | Periostin in chronic liver diseases: Current research and future perspectives. | 2019 | Details |
| A11295 | 30951375 | FASEB J | The immunoregulatory effects of CD8 T-cell-derived perforin on diet-induced nonalcoholic steatohepatitis. | 2019 | Details |
| A11309 | 30945293 | J Pathol | Bone marrow-derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells. | 2019 | Details |
| A11569 | 30835899 | J Leukoc Biol | Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis. | 2019 | Details |
| A11690 | 30790016 | Rheumatol Int | Liver dysfunction in anti-melanoma differentiation-associated gene 5 antibody-positive patients with dermatomyositis. | 2019 | Details |
| A11699 | 30787626 | Diabetes Metab Syndr Obes | Relationship between nonalcoholic fatty liver disease and bone mineral density in adolescents with obesity: a meta-analysis. | 2019 | Details |
| A11858 | 30706504 | Hepatology | Association Between Nonalcoholic Fatty Liver Disease and Reduced Bone Mineral Density in Children: A Meta-Analysis. | 2019 | Details |
| A11983 | 30658519 | Int J Mol Sci | Gut-Liver Axis, Gut Microbiota, and Its Modulation in the Management of Liver Diseases: A Review of the Literature. | 2019 | Details |
| A12002 | 30652107 | Microb Cell | Imbalance in gut microbes from babies born to obese mothers increases gut permeability and myeloid cell adaptations that provoke obesity and NAFLD. | 2018 | Details |
| A12060 | 30619336 | Front Immunol | Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis. | 2018 | Details |
| A12105 | 30600540 | Aliment Pharmacol Ther | Systematic review with meta-analysis: non-alcoholic fatty liver disease is associated with a history of osteoporotic fractures but not with low bone mineral density. | 2019 | Details |
| A12229 | 30555477 | Front Immunol | Macrophages in the Aging Liver and Age-Related Liver Disease. | 2018 | Details |
| A12234 | 30553186 | Micron | Primary cultured neuronal networks and type 2 diabetes model mouse fatty liver tissues in aqueous liquid observed by atmospheric SEM (ASEM): Staining preferences of metal solutions. | 2018 | Details |
| A12253 | 30545408 | J Med Case Rep | Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports. | 2018 | Details |
| A12273 | 30538805 | Oxid Med Cell Longev | c-Met Signaling Protects from Nonalcoholic Steatohepatitis- (NASH-) Induced Fibrosis in Different Liver Cell Types. | 2018 | Details |
| A12360 | 30487332 | Clin Calcium | [Secondary osteoporosis. Bone disease in liver cirrhosis.] | 2019 | Details |
| A12408 | 30467685 | Hormones (Athens) | Noggin levels in nonalcoholic fatty liver disease: the effect of vitamin E treatment. | 2018 | Details |
| A12437 | 30455376 | Diabetes | HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. | 2018 | Details |
| A12507 | 30415518 | Ceylon Med J | Clinical characteristics and outcomes of hepatocellular carcinoma: results from prospective study, from a tertiary referral center in 
Sri Lanka | 2018 | Details |
| A12529 | 30408605 | Contemp Clin Trials | European paediatric non-alcoholic fatty liver disease registry (EU-PNAFLD): Design and rationale. | 2018 | Details |
| A12552 | 30394678 | J Int AIDS Soc | Predictive factors associated with liver fibrosis and steatosis by transient elastography in patients with HIV mono-infection under long-term combined antiretroviral therapy. | 2018 | Details |
| A12697 | 30323574 | Clin Interv Aging | Novel insights into the relationship between nonalcoholic fatty liver disease and osteoporosis. | 2018 | Details |
| A12722 | 30315891 | Diabetes Metab | Association between non-alcoholic fatty liver disease and bone turnover biomarkers in post-menopausal women with type 2 diabetes. | 2018 | Details |
| A12841 | 30259536 | Hepatology | Angiopoietin-2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12933 | 30219279 | J Control Release | Therapeutic inhibition of spleen tyrosine kinase in inflammatory macrophages using PLGA nanoparticles for the treatment of non-alcoholic steatohepatitis. | 2018 | Details |
| A12947 | 30213555 | Gastroenterology | Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice. | 2018 | Details |
| A13023 | 30176114 | Liver Int | Relationship between non-alcoholic steatohepatitis, PNPLA3 I148M genotype and bone mineral density in adolescents. | 2018 | Details |
| A13134 | 30122075 | Climacteric | Association between nonalcoholic fatty liver disease and bone mineral density in postmenopausal women. | 2018 | Details |
| A13140 | 30120405 | Pediatr Res | Hepatic fat content and bone mineral density in children with overweight/obesity. | 2018 | Details |
| A13229 | 30073778 | J Diabetes | Effect of pioglitazone on bone mineral density in patients with nonalcoholic steatohepatitis: A 36-month clinical trial. | 2018 | Details |
| A13288 | 30049586 | Bioorg Med Chem | Design, synthesis and biological evaluation of novel spiro-pentacylamides as acetyl-CoA carboxylase inhibitors. | 2018 | Details |
| A13579 | 29897928 | PLoS One | Nonalcoholic fatty liver disease with elevated alanine aminotransferase levels is negatively associated with bone mineral density: Cross-sectional study in U.S. adults. | 2018 | Details |
| A13736 | 29785076 | World J Gastroenterol | Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease. | 2018 | Details |
| A13780 | 29761170 | Hepatol Commun | Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice. | 2018 | Details |
| A13816 | 29743888 | Gastroenterol Res Pract | Correlation between Helicobacter pylori Infection and Metabolic Abnormality in General Population: A Cross-Sectional Study. | 2018 | Details |
| A14143 | 29565507 | Eur Rev Med Pharmacol Sci | Analysis of the correlation between non-alcoholic fatty liver disease and bone metabolism indicators in healthy middle-aged men. | 2018 | Details |
| A14249 | 29506157 | J Clin Endocrinol Metab | Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose. | 2018 | Details |
| A14267 | 29493093 | HIV Med | Highlights of the 2017 European AIDS Clinical Society (EACS) Guidelines for the treatment of adult HIV-positive persons version 9.0. | 2018 | Details |
| A14292 | 29479832 | Liver Int | Osteoporosis in chronic liver disease. | 2018 | Details |
| A14583 | 29341046 | Horm Metab Res | Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty Liver Disease in Obese Children. | 2018 | Details |
| A14588 | 29336868 | Eur J Intern Med | The therapeutic potential of targeting the peripheral endocannabinoid/CB1 receptor system. | 2018 | Details |
| A14620 | 29321172 | Diabetes | Modest Decreases in Endogenous All-trans-Retinoic Acid Produced by a Mouse Rdh10 Heterozygote Provoke Major Abnormalities in Adipogenesis and Lipid Metabolism. | 2018 | Details |
| A14631 | 29315766 | Hepatology | Disruption of adenosine 2A receptor exacerbates NAFLD through increasing inflammatory responses and SREBP1c activity. | 2018 | Details |
| A14697 | 29286155 | Mol Med Rep | Mesenchymal stem cells reverse high‑fat diet‑induced non‑alcoholic fatty liver disease through suppression of CD4+ T lymphocytes in mice. | 2017 | Details |
| A14804 | 29224108 | Adv Exp Med Biol | Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men. | 2017 | Details |
| A14925 | 29170905 | Endocrine | Irisin in metabolic diseases. | 2017 | Details |
| A15203 | 29051986 | Osteoporos Int | The relationship between fatty liver index and bone mineral density in Koreans: KNHANES 2010-2011. | 2017 | Details |
| A15325 | 28966079 | Trends Endocrinol Metab | Multifunctional p62 Effects Underlie Diverse Metabolic Diseases. | 2017 | Details |
| A15448 | 28902430 | J Bone Miner Res | Reduced Serum IGF-1 Associated With Hepatic Osteodystrophy Is a Main Determinant of Low Cortical but Not Trabecular Bone Mass. | 2017 | Details |
| A15603 | 28817367 | Nutr Clin Pract | Nutrition Implications for Long-Term Survivors of Pancreatic Cancer Surgery [Formula: see text]. | 2017 | Details |
| A15689 | 28759632 | PLoS One | Significant liver fibrosis assessed using liver transient elastography is independently associated with low bone mineral density in patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A15701 | 28752050 | Mol Metab | Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders. | 2017 | Details |
| A15839 | 28687713 | Clin Sci (Lond) | TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival. | 2017 | Details |
| A15848 | 28683306 | Cell Rep | RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15876 | 28676019 | Curr Vasc Pharmacol | Statins: An Under-Appreciated Asset for the Prevention and the Treatment of NAFLD or NASH and the Related Cardiovascular Risk. | 2018 | Details |
| A16034 | 28598982 | PLoS One | α-Mangostin ameliorates hepatic steatosis and insulin resistance by inhibition C-C chemokine receptor 2. | 2017 | Details |
| A16036 | 28598410 | Children (Basel) | Pediatric Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16228 | 28498022 | Curr Med Res Opin | Thyroid hormone analogs for the treatment of dyslipidemia: past, present, and future. | 2017 | Details |
| A16317 | 28462384 | Cell Mol Gastroenterol Hepatol | TRIF Differentially Regulates Hepatic Steatosis and Inflammation/Fibrosis in Mice. | 2017 | Details |
| A16388 | 28424263 | J Biol Chem | The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. | 2017 | Details |
| A16498 | 28351752 | Exp Cell Res | Deficiency of CKIP-1 aggravates high-fat diet-induced fatty liver in mice. | 2017 | Details |
| A16507 | 28348479 | World J Gastroenterol | Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle. | 2017 | Details |
| A16563 | 28314735 | Gut | Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases. | 2017 | Details |
| A16692 | 28241279 | JAMA Intern Med | Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis: A Meta-analysis. | 2017 | Details |
| A16751 | 28210913 | Int Urol Nephrol | Dietary and commercialized fructose: Sweet or sour? | 2017 | Details |
| A16766 | 28194019 | Cell Mol Immunol | IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity. | 2017 | Details |
| A16898 | 28105511 | Calcif Tissue Int | Bone Density in the Obese Child: Clinical Considerations and Diagnostic Challenges. | 2017 | Details |
| A16939 | 28082803 | World J Gastroenterol | Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets. | 2016 | Details |
| A16983 | 28063601 | Clin Radiol | Bone marrow fat content is correlated with hepatic fat content in paediatric non-alcoholic fatty liver disease. | 2017 | Details |
| A17015 | 28044208 | J Gastroenterol | Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis. | 2017 | Details |
| A17056 | 28019064 | Hepatol Res | Novel antidiabetic medications for non-alcoholic fatty liver disease with type 2 diabetes mellitus. | 2017 | Details |
| A17133 | 27973461 | Minerva Endocrinol | Bone metabolism in non-alcoholic fatty liver disease: vitamin D status and bone mineral density. | 2016 | Details |
| A17179 | 27928661 | J Bone Miner Metab | Nonalcoholic fatty liver disease and osteoporosis: a systematic review and meta-analysis. | 2016 | Details |
| A17231 | 27898698 | PLoS One | Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice. | 2016 | Details |
| A17254 | 27889556 | Int Immunopharmacol | Compact bone-derived mesenchymal stem cells attenuate nonalcoholic steatohepatitis in a mouse model by modulation of CD4 cells differentiation. | 2016 | Details |