Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19121 | 26748347 | Atherosclerosis | Improvement in non-alcoholic fatty liver disease severity is associated with a reduction in carotid intima-media thickness progression. | 2015 | Details |
| A19150 | 26727365 | PLoS One | Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats. | 2016 | Details |
| A19167 | 30280852 | Eksp Klin Gastroenterol | [CURRENT ISSUES IN THE CHOICE OF ANTIHYPERTENSIVE THERAPY IN PATIENTS WITH METABOLIC SYNDROME AND RELATED NON-ALCOHOLIC FATTY LIVER DISEASE]. | 2018 | Details |
| A19289 | 26648069 | Curr Drug Targets | Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib. | 2016 | Details |
| A19385 | 26597602 | J Diabetes Complications | Chronic fructose intake accelerates non-alcoholic fatty liver disease in the presence of essential hypertension. | 2015 | Details |
| A19440 | 26567728 | Acta Pharmacol Sin | Inverse relationship between serum osteocalcin levels and nonalcoholic fatty liver disease in postmenopausal Chinese women with normal blood glucose levels. | 2015 | Details |
| A19470 | 26545658 | Nutr Hosp | NUTRITIONAL STATUS, DIET AND NON-ALCOHOLIC FATTY LIVER DISEASE IN ELDERS. | 2015 | Details |
| A19678 | 28294798 | Kardiologiia | [Safety and Efficacy of Amlodipine, Lisinopril and Rosuvastatin Therapy in Patients With Metabolic Syndrome and Nonalcoholic Fatty Liver Disease]. | 2015 | Details |
| A19685 | 26411937 | Nihon Eiseigaku Zasshi | [Mechanism Analysis and Prevention of Pathogenesis of Nonalcoholic Steatohepatitis]. | 2015 | Details |
| A19692 | 26407654 | Eur J Pharmacol | Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. | 2015 | Details |
| A20721 | 25776455 | Am J Cardiol | Relation of nonalcoholic fatty liver disease and Framingham Risk Score to flow-mediated dilation in patients with cardiometabolic risk factors. | 2015 | Details |
| A20843 | 25693058 | J Hypertens | Blood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk. | 2015 | Details |
| A20856 | 25683947 | Eur Rev Med Pharmacol Sci | Serum uric acid and non-alcoholic fatty liver disease in non-hypertensive Chinese adults: the Cardiometabolic Risk in Chinese (CRC) study. | 2015 | Details |
| A20929 | 25634387 | Indian Heart J | Prevalence of nonalcoholic fatty liver disease (NAFLD) in patients of cardiovascular diseases and its association with hs-CRP and TNF-α. | 2014 | Details |
| A20934 | 25632192 | World J Gastroenterol | Characteristics of hepatocellular carcinoma in cirrhotic and non-cirrhotic non-alcoholic fatty liver disease. | 2015 | Details |
| A21144 | 25516385 | J Gastroenterol | The association between retinal microvascular changes, metabolic risk factors, and liver histology in pediatric patients with non-alcoholic fatty liver disease (NAFLD). | 2014 | Details |
| A21473 | 25296075 | Arq Gastroenterol | Age and gender may influence the results of Roux-en-Y gastric bypass? Metabolic syndrome parameters. | 2015 | Details |
| A21476 | 25294377 | J Zhejiang Univ Sci B | Association between non-alcoholic fatty liver disease and arterial stiffness in the non-obese, non-hypertensive, and non-diabetic young and middle-aged Chinese population. | 2014 | Details |
| A21694 | 25114474 | Indian J Surg Oncol | Steatohepatitic hepatocellular carcinoma-a case report with literature review. | 2014 | Details |
| A21802 | 25034293 | Dig Dis | Treatment of non-alcoholic fatty liver disease. | 2014 | Details |
| A21897 | 24975050 | Basic Clin Pharmacol Toxicol | Effects of antihypertensive and triglyceride-lowering agents on hepatic copper concentrations in rats with fatty liver disease. | 2014 | Details |
| A21992 | 24905085 | Liver Int | Renin-angiotensin system and fibrosis in non-alcoholic fatty liver disease. | 2014 | Details |
| A22241 | 24729784 | Gastroenterol Res Pract | Chronic kidney disease and nonalcoholic Fatty liver disease-is there a link? | 2014 | Details |
| A22488 | 24520400 | PLoS One | Association between noninvasive fibrosis markers and chronic kidney disease among adults with nonalcoholic fatty liver disease. | 2014 | Details |
| A22577 | 24448653 | Dig Dis Sci | A possible role of chenodeoxycholic acid and glycine-conjugated bile acids in fibrotic steatohepatitis in a dietary rat model. | 2014 | Details |
| A22580 | 24445219 | J Hepatol | Development of new fatty liver, or resolution of existing fatty liver, over five years of follow-up, and risk of incident hypertension. | 2014 | Details |
| A22601 | 24424317 | Int J Mol Sci | Evaluation of hepatic tissue blood flow using xenon computed tomography with fibrosis progression in nonalcoholic fatty liver disease: comparison with chronic hepatitis C. | 2014 | Details |
| A22700 | 25796814 | Wiad Lek | Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis. | 2014 | Details |
| A22939 | 24190226 | Int J Mol Med | Hypertension exacerbates liver injury and hepatic fibrosis induced by a choline-deficient L-amino acid-defined diet in rats. | 2013 | Details |
| A23029 | 24098813 | PLoS One | Fatty liver is associated with transcriptional downregulation of stearoyl-CoA desaturase and impaired protein dimerization. | 2013 | Details |
| A23057 | 28839736 | Frontline Gastroenterol | Piloting a multidisciplinary clinic for the management of non-alcoholic fatty liver disease: initial 5-year experience. | 2013 | Details |
| A23062 | 24071521 | Life Sci | High-fat-cholesterol diet mainly induced necrosis in fibrotic steatohepatitis rat by suppressing caspase activity. | 2013 | Details |
| A23092 | 24047280 | Clin Exp Hypertens | The association between serum ferritin level, microalbuminuria and non-alcoholic fatty liver disease in non-diabetic, non-hypertensive men. | 2013 | Details |
| A23155 | 23998651 | Liver Int | Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat. | 2013 | Details |
| A23157 | 23997767 | Int J Endocrinol | Effect of Telmisartan or Losartan for Treatment of Nonalcoholic Fatty Liver Disease: Fatty Liver Protection Trial by Telmisartan or Losartan Study (FANTASY). | 2013 | Details |
| A23180 | 23981577 | Cancer Lett | Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions. | 2013 | Details |
| A23224 | 23940514 | PLoS One | NT pro BNP plasma level and atrial volume are linked to the severity of liver cirrhosis. | 2013 | Details |
| A23278 | 23905912 | Exp Clin Transplant | Effect of ethnicity on liver transplant for hepatocellular carcinoma. | 2013 | Details |
| A23372 | 23837080 | Australas Med J | Primary non-alcoholic fatty liver disease in hypertensive patients. | 2013 | Details |
| A23609 | 23627940 | Curr Med Chem | Pharmacological inhibition of protein tyrosine phosphatase 1B: a promising strategy for the treatment of obesity and type 2 diabetes mellitus. | 2013 | Details |
| A23666 | 23584921 | High Blood Press Cardiovasc Prev | Non-alcoholic fatty liver disease is not associated with vitamin D deficiency in essential hypertension. | 2013 | Details |
| A23716 | 23544269 | Nagoya J Med Sci | Simple and rapid quantitation of 21 bile acids in rat serum and liver by UPLC-MS-MS: effect of high fat diet on glycine conjugates of rat bile acids. | 2013 | Details |
| A23776 | 23489555 | Basic Clin Pharmacol Toxicol | Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with fatty liver. | 2013 | Details |
| A24229 | 23075871 | Dig Dis | Clinical spectrum and therapy of non-alcoholic steatohepatitis. | 2012 | Details |
| A24338 | 22986520 | Cardiology | The association between nonalcoholic fatty liver disease, metabolic syndrome and arterial stiffness in nondiabetic, nonhypertensive individuals. | 2012 | Details |
| A24392 | 22940679 | J Hypertens | High ambulatory blood pressure values associated with non-alcoholic fatty liver in middle-aged adults. | 2012 | Details |
| A24434 | 22899407 | Georgian Med News | [Treatment of nonalcogolic fatty disease of liver]. | 2012 | Details |
| A24467 | 22868011 | J Coll Physicians Surg Pak | Serum cholesterol: could it be a sixth parameter of Child-Pugh scoring system in cirrhotics due to viral hepatitis? | 2012 | Details |
| A24502 | 22827449 | Clin Sci (Lond) | Cardiovascular disease is associated with high-fat-diet-induced liver damage and up-regulation of the hepatic expression of hypoxia-inducible factor 1α in a rat model. | 2013 | Details |
| A24532 | 22796347 | Nutr Metab Cardiovasc Dis | Ambulatory arterial stiffness indices and non-alcoholic fatty liver disease in essential hypertension. | 2012 | Details |
| A24674 | 22617751 | Curr Opin Lipidol | Nonalcoholic fatty liver disease and lipids. | 2012 | Details |
| A24716 | 22569299 | Life Sci | The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. | 2012 | Details |
| A24789 | 22490991 | J Endocrinol Invest | Non-alcoholic fatty liver disease is independently associated with left ventricular hypertrophy in hypertensive Type 2 diabetic individuals. | 2012 | Details |
| A24828 | 22457860 | J Gastrointestin Liver Dis | Serum ferritin levels do not predict the stage of underlying non-alcoholic fatty liver disease. | 2012 | Details |
| A25021 | 22240297 | J Proteomics | Changes in hepatic protein expression in spontaneously hypertensive rats suggest early stages of non-alcoholic fatty liver disease. | 2012 | Details |
| A25189 | 22105311 | Eur J Nutr | Cardioprotective and hepatoprotective effects of ellagitannins from European oak bark (Quercus petraea L.) extract in rats. | 2011 | Details |
| A25342 | 21946918 | Mol Med Rep | Nifedipine prevents hepatic fibrosis in a non-alcoholic steatohepatitis model induced by an L-methionine-and choline-deficient diet. | 2011 | Details |
| A25366 | 21915061 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease is associated with blood pressure in hypertensive and nonhypertensive individuals from the general population with normal levels of alanine aminotransferase. | 2011 | Details |
| A25409 | 21883436 | Diabet Med | Increased prevalence of chronic kidney disease in patients with Type 1 diabetes and non-alcoholic fatty liver. | 2012 | Details |
| A25431 | 21853259 | Environ Health Prev Med | Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. | 2011 | Details |
| A25472 | 21795844 | J Endocrinol Invest | Increased prevalence of cardiovascular disease in Type 1 diabetic patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25920 | 21327395 | Cell Tissue Res | Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation. | 2011 | Details |
| A25977 | 21245286 | Drug Metab Dispos | Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. | 2011 | Details |
| A26054 | 21160985 | World J Hepatol | Combination drug treatment in patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26232 | 20858492 | Gastroenterology | Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. | 2010 | Details |
| A26284 | 20731130 | Eksp Klin Gastroenterol | [Splenoportal blood flow with nonalcoholic fatty liver disease]. | 2010 | Details |
| A26312 | 20661251 | Int J Obes (Lond) | Visceral adiposity and insulin resistance are independent predictors of the presence of non-cirrhotic NAFLD-related portal hypertension. | 2010 | Details |
| A26547 | 20227260 | Nutr Metab Cardiovasc Dis | Endothelial dysfunction and non-alcoholic liver steatosis in hypertensive patients. | 2010 | Details |
| A26579 | 20175770 | Aliment Pharmacol Ther | Clinical predictors of fibrosis in patients with chronic liver disease. | 2010 | Details |
| A26657 | 20036859 | Front Biosci (Elite Ed) | Biochemical characteristics and risk factors in non-alcoholic fatty liver. | 2010 | Details |
| A26666 | 20025483 | Pathology | Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats. | 2010 | Details |
| A26801 | 19756959 | Mol Cell Biochem | Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. | 2009 | Details |
| A27047 | 19278843 | Nutr Metab Cardiovasc Dis | Non-alcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in essential hypertension. | 2009 | Details |
| A27214 | 18972077 | Adv Ther | Angiotensin receptor blockers in the treatment of NASH/NAFLD: could they be a first-class option? | 2008 | Details |
| A27242 | 18854760 | J Hypertens | Nonalcoholic fatty liver disease, adiponectin and insulin resistance in dipper and nondipper essential hypertensive patients. | 2008 | Details |
| A27391 | 18486983 | J Hepatol | Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats. | 2008 | Details |
| A27419 | 18420211 | Atherosclerosis | Do we need to consider inflammatory markers when we treat atherosclerotic disease? | 2008 | Details |
| A27431 | 18396752 | Acta Gastroenterol Belg | The metabolic syndrome and the liver. | 2008 | Details |
| A27471 | 18328362 | Metabolism | Nonalcoholic fatty liver disease predicts chronic kidney disease in nonhypertensive and nondiabetic Korean men. | 2008 | Details |
| A27509 | 18239590 | Obesity (Silver Spring) | ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. | 2007 | Details |
| A27621 | 17900249 | Liver Int | Clinicopathological improvement of non-alcoholic steatohepatitis associated with weight loss during a 14-year follow-up period. | 2007 | Details |
| A27746 | 17539815 | Hepatol Res | A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease. | 2007 | Details |
| A27846 | 17273155 | J Hum Hypertens | Hypertension and fatty liver: guilty by association? | 2007 | Details |
| A28167 | 16231591 | Eur Rev Med Pharmacol Sci | Steatosis and portal hypertension. | 2006 | Details |
| A28279 | 15824194 | Hypertension | Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction. | 2005 | Details |
| A28377 | 15331071 | Clin Liver Dis | Pharmacologic management of nonalcoholic fatty liver disease. | 2004 | Details |
| A28405 | 15194655 | Gut | Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes: role of insulin resistance. | 2004 | Details |
| A28467 | 14499789 | Am J Gastroenterol | Nonalcoholic fatty liver disease in patients with hepatitis C is associated with features of the metabolic syndrome. | 2003 | Details |
| A29597 | 33817519 | ACS Omega | One-Pot Extraction and Quantification Method for Bile Acids in the Rat Liver by Capillary Liquid Chromatography Tandem Mass Spectrometry. | 2021 | Details |
| A29879 | 33344141 | Adv Sci (Weinh) | Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30652 | 32039404 | JHEP Rep | Beta-blockers in cirrhosis: Evidence-based indications and limitations. | 2019 | Details |
| A31766 | 29899851 | Oncotarget | Association of mRNA expression of iron metabolism-associated genes and progression of non-alcoholic steatohepatitis in rats. | 2018 | Details |
| A32089 | 29215307 | Biotech Histochem | Effects of intravitreous sodium hydrosulfide on intraocular pressure and retinopathy in ocular hypertensive rats. | 2017 | Details |
| A33966 | 24763197 | Exp Mol Med | Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice. | 2014 | Details |
| A34298 | 23824403 | Dig Dis Sci | Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats. | 2013 | Details |
| A34863 | 22403205 | J Am Board Fam Med | Navigating change: how outreach facilitators can help clinicians improve patient outcomes. | 2012 | Details |
| A34937 | 22182635 | Asian Pac J Trop Med | Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb--a review. | 2012 | Details |
| A34947 | 22176027 | Hepatol Res | Spontaneously hypertensive rats develop pronounced hepatic steatosis induced by choline-deficient diet: Evidence for hypertension as a potential enhancer in non-alcoholic steatohepatitis. | 2011 | Details |
| A35953 | 19344467 | Am J Transplant | Outcome after liver transplantation for NASH cirrhosis. | 2009 | Details |
| A36348 | 18392239 | J Gastrointestin Liver Dis | Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet. | 2008 | Details |