Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00794 | 34965016 | Clin Transl Med | Lactobacillus lactis and Pediococcus pentosaceus-driven reprogramming of gut microbiome and metabolome ameliorates the progression of non-alcoholic fatty liver disease. | 2021 | Details |
| A00795 | 34964604 | Biomacromolecules | Construction of Glycogen-Based Nanoparticles Loaded with Resveratrol for the Alleviation of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00797 | 34964117 | Compr Physiol | Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease. | 2021 | Details |
| A00801 | 34960036 | Nutrients | Protective Effects of Sesamol against Liver Oxidative Stress and Inflammation in High-Fat Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A00803 | 34959992 | Nutrients | Curcumin in Metabolic Health and Disease. | 2021 | Details |
| A00822 | 34957088 | Front Cell Dev Biol | Molecular Immune Mechanism of Intestinal Microbiota and Their Metabolites in the Occurrence and Development of Liver Cancer. | 2021 | Details |
| A00825 | 34956171 | Front Immunol | Hepatic Macrophage as a Key Player in Fatty Liver Disease. | 2021 | Details |
| A00826 | 34956080 | Front Endocrinol (Lausanne) | Efficacy and Safety of GLP-1 Receptor Agonists in Patients With Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A00833 | 34954342 | Biochim Biophys Acta Mol Basis Dis | Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse. | 2021 | Details |
| A00840 | 34951153 | Hepatol Commun | Angiotensin Converting Enzyme-2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver. | 2021 | Details |
| A00846 | 34950107 | Front Endocrinol (Lausanne) | Analysis of N6-Methyladenosine Methylation Modification in Fructose-Induced Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00854 | 34945677 | Foods | Lactobacillus plantarum MA2 Ameliorates Methionine and Choline-Deficient Diet Induced Non-Alcoholic Fatty Liver Disease in Rats by Improving the Intestinal Microecology and Mucosal Barrier. | 2021 | Details |
| A00855 | 34945573 | Foods | The Regulatory Effects of Citrus Peel Powder on Liver Metabolites and Gut Flora in Mice with Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A00859 | 34944732 | Biomedicines | Therapeutic Opportunities of IL-22 in Non-Alcoholic Fatty Liver Disease: From Molecular Mechanisms to Clinical Applications. | 2021 | Details |
| A00869 | 34944525 | Biomolecules | A System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach. | 2021 | Details |
| A00870 | 34944452 | Biomolecules | Digital Pathology Enables Automated and Quantitative Assessment of Inflammatory Activity in Patients with Chronic Liver Disease. | 2021 | Details |
| A00871 | 34944021 | Cells | IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism. | 2021 | Details |
| A00872 | 34943946 | Cells | Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese Ay Mice. | 2021 | Details |
| A00875 | 34943814 | Cells | Exercise-Induced Irisin Decreases Inflammation and Improves NAFLD by Competitive Binding with MD2. | 2021 | Details |
| A00880 | 34943134 | Antioxidants (Basel) | Hepatoprotective Effect of Bee Bread in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Rats: Impact on Oxidative Stress and Inflammation. | 2021 | Details |
| A00882 | 34943103 | Antioxidants (Basel) | Association of Serum Bilirubin and Functional Variants of Heme Oxygenase 1 and Bilirubin UDP-Glucuronosyl Transferase Genes in Czech Adult Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00884 | 34942286 | J Hepatol | Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease. | 2021 | Details |
| A00898 | 34935645 | JCI Insight | Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring. | 2021 | Details |
| A00908 | 34933425 | Zhonghua Gan Zang Bing Za Zhi | [Intestinal flora polymorphisms with different lesional stages in an animal model of MAFLD]. | 2021 | Details |
| A00918 | 34929996 | Minerva Gastroenterol (Torino) | Evaluation of MACK-3 parameters, metabolic and fibrotic characteristics of non-alcoholic fatty liver disease patients with hypertension. | 2021 | Details |
| A00926 | 34927282 | Drug Dev Res | Schisandrin B ameliorates non-alcoholic liver disease through anti-inflammation activation in diabetic mice. | 2021 | Details |
| A00930 | 34926735 | Regen Ther | Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair. | 2021 | Details |
| A00942 | 34923456 | Wiad Lek | INTESTINAL LESIONS OCCURRING IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AFTER SUFFERING THE COVID-19 INFECTION. | 2021 | Details |
| A00945 | 34922644 | Lancet Diabetes Endocrinol | Effective, disease-modifying, clinical approaches to patients with mild-to-moderate hypertriglyceridaemia. | 2021 | Details |
| A00946 | 34922604 | Trials | Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the "Brazilian Omega Study" (BROS)-a randomized controlled trial. | 2021 | Details |
| A00949 | 34922061 | Clin Res Hepatol Gastroenterol | Upregulated NLRP3 inflammasome activation is attenuated by anthocyanins in patients with nonalcoholic fatty liver disease: A case-control and an intervention study. | 2021 | Details |
| A00950 | 34921696 | Biofactors | High-fat-induced nonalcoholic fatty liver potentiates vulnerability to and the severity of viral hepatitis in a C3H/HeN mouse model. | 2021 | Details |
| A00951 | 34921208 | Sci Rep | Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis. | 2021 | Details |
| A00969 | 34915801 | Pharm Biol | Jiang Zhi Granule protects immunological barrier of intestinal mucosa in rats with non-alcoholic steatohepatitis. | 2021 | Details |
| A00971 | 34915054 | J Hepatol | A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH. | 2021 | Details |
| A00973 | 34914973 | Exp Mol Pathol | TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop. | 2021 | Details |
| A00974 | 34914849 | J Intern Med | Liver damage promotes pro-inflammatory T-cell responses against apolipoprotein B-100. | 2022 | Details |
| A00987 | 34909677 | Curr Res Pharmacol Drug Discov | ATP citrate lyase inhibitor Bempedoic Acid alleviate long term HFD induced NASH through improvement in glycemic control, reduction of hepatic triglycerides & total cholesterol, modulation of inflammatory & fibrotic genes and improvement in NAS score. | 2021 | Details |
| A01010 | 34904028 | World J Hepatol | Liver involvement in inflammatory bowel disease: What should the clinician know? | 2021 | Details |
| A01012 | 34903973 | Iran J Pharm Res | Benefits and Risks of Melatonin in Hepatic and Pancreatic Disorders; A Review of Clinical Evidences. | 2021 | Details |
| A01015 | 34903499 | Dig Liver Dis | Colonic inflammation accelerates the progression of liver disease: A protective role of dipotassium glycyrrhizate. | 2021 | Details |
| A01020 | 34901236 | Front Cardiovasc Med | Statins in Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01022 | 34900816 | J Diabetes Metab Disord | The effects of high fructose fruits and honey on the serum level of metabolic factors and nonalcoholic fatty liver disease. | 2021 | Details |
| A01027 | 34899351 | Front Pharmacol | Network Pharmacology-Based Analysis of Pogostemon cablin (Blanco) Benth Beneficial Effects to Alleviate Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A01035 | 34895316 | Skelet Muscle | Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study. | 2021 | Details |
| A01050 | 34887931 | Evid Based Complement Alternat Med | Pharmacodynamic Evaluation of the Gexia Zhuyu Decoction in the Treatment of NAFLD and the Molecular Mechanism Underlying the TRPM4 Pathway Regulation. | 2021 | Details |
| A01053 | 34887631 | World J Gastroenterol | Non-alcoholic fatty liver disease in patients with intestinal, pulmonary or skin diseases: Inflammatory cross-talk that needs a multidisciplinary approach. | 2021 | Details |
| A01055 | 34886772 | Curr Alzheimer Res | Metabolic Syndrome, Alzheimer's Disease, and Covid 19: A Possible Correlation. | 2021 | Details |
| A01056 | 34884968 | Int J Mol Sci | Neochlorogenic Acid Attenuates Hepatic Lipid Accumulation and Inflammation via Regulating miR-34a In Vitro. | 2021 | Details |
| A01071 | 34879108 | PLoS One | PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells. | 2021 | Details |
| A01075 | 34877270 | World J Clin Cases | Pharmaconutrition strategy to resolve SARS-CoV-2-induced inflammatory cytokine storm in non-alcoholic fatty liver disease: Omega-3 long-chain polyunsaturated fatty acids. | 2021 | Details |
| A01107 | 34867384 | Front Pharmacol | Effects of Nigella sativa, Camellia sinensis, and Allium sativum as Food Additives on Metabolic Disorders, a Literature Review. | 2021 | Details |
| A01118 | 34863942 | Mol Metab | The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. | 2021 | Details |
| A01119 | 34863940 | Mol Metab | URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice. | 2021 | Details |
| A01136 | 34859106 | J Immunol Res | Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD. | 2021 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01160 | 34848839 | Exp Mol Med | Roles of IκB kinases and TANK-binding kinase 1 in hepatic lipid metabolism and nonalcoholic fatty liver disease. | 2021 | Details |
| A01167 | 34847213 | Food Funct | Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence. | 2021 | Details |
| A01188 | 34835949 | Nutrients | Effects of Lingonberry (Vaccinium vitis-idaea L.) Supplementation on Hepatic Gene Expression in High-Fat Diet Fed Mice. | 2021 | Details |
| A01190 | 34835476 | Microorganisms | Impact of Helicobacter pylori-Related Metabolic Syndrome Parameters on Arterial Hypertension. | 2021 | Details |
| A01194 | 34831201 | Cells | Lipid Metabolism Disorders in the Comorbid Course of Nonalcoholic Fatty Liver Disease and Chronic Obstructive Pulmonary Disease. | 2021 | Details |
| A01197 | 34830641 | J Clin Med | Liver Pathology in Children with Diagnosed Inflammatory Bowel Disease-A Single Center Experience. | 2021 | Details |
| A01200 | 34830072 | Int J Mol Sci | T Cell Subsets and Natural Killer Cells in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01208 | 34829565 | Antioxidants (Basel) | Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity. | 2021 | Details |
| A01218 | 34825156 | JHEP Rep | Bile acids contribute to the development of non-alcoholic steatohepatitis in mice. | 2021 | Details |
| A01219 | 34825068 | Biochem Biophys Rep | Metformin treatment reverses high fat diet- induced non-alcoholic fatty liver diseases and dyslipidemia by stimulating multiple antioxidant and anti-inflammatory pathways. | 2021 | Details |
| A01220 | 34823548 | J Transl Med | CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype. | 2021 | Details |
| A01226 | 34822420 | Metabolites | Hepatic Response of Magnesium-Restricted Wild Type Mice. | 2021 | Details |
| A01229 | 34821899 | Food Funct | Maternal sucralose exposure induces Paneth cell defects and exacerbates gut dysbiosis of progeny mice. | 2021 | Details |
| A01231 | 34821035 | Liver Int | Inflammatory activity affects the accuracy of liver stiffness measurement by transient elastography but not by two-dimensional shear wave elastography in non-alcoholic fatty liver disease. | 2021 | Details |
| A01233 | 34819792 | Saudi Pharm J | Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease. | 2021 | Details |
| A01245 | 34815444 | Sci Rep | A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates. | 2021 | Details |
| A01253 | 34813997 | Biomed Pharmacother | SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice. | 2021 | Details |
| A01265 | 34808701 | Phytother Res | Esculetin: A review of its pharmacology and pharmacokinetics. | 2021 | Details |
| A01269 | 34808388 | Bioorg Med Chem Lett | Design, synthesis and activity evaluation of prodrug form JBP485 and Vitamin E for alleviation of NASH. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01283 | 34803490 | Int J Biol Sci | SOCS2 Suppresses Inflammation and Apoptosis during NASH Progression through Limiting NF-κB Activation in Macrophages. | 2021 | Details |
| A01293 | 34799486 | Curr Opin Lipidol | Fatty liver and cerebrovascular disease: plausible association and possible mechanisms. | 2022 | Details |
| A01299 | 34797530 | Rheumatol Ther | Psoriatic Arthritis: The Influence of Co-morbidities on Drug Choice. | 2021 | Details |
| A01302 | 34795655 | Front Microbiol | Gut Microbiome-Mediated Alteration of Immunity, Inflammation, and Metabolism Involved in the Regulation of Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A01303 | 34795650 | Front Microbiol | Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01304 | 34795391 | Commun Biol | Precancerous liver diseases do not cause increased mutagenesis in liver stem cells. | 2021 | Details |
| A01307 | 34794237 | Biomed Pharmacother | Anti-inflammatory and anti-fibrotic effects of modafinil in nonalcoholic liver disease. | 2021 | Details |
| A01308 | 34794234 | Biomed Pharmacother | Saroglitazar and Hepano treatment offers protection against high fat high fructose diet induced obesity, insulin resistance and steatosis by modulating various class of hepatic and circulating lipids. | 2021 | Details |
| A01313 | 34791524 | Int J Colorectal Dis | Disease activity in inflammatory bowel disease patients is associated with increased liver fat content and liver fibrosis during follow-up. | 2021 | Details |
| A01314 | 34791370 | J Nutr | Dietary and Lifestyle Inflammation Scores Are Inversely Associated with Metabolic-Associated Fatty Liver Disease among Iranian Adults: A Nested Case-Control Study. | 2022 | Details |
| A01317 | 34789244 | Lipids Health Dis | Protective effect of quercetin against the metabolic dysfunction of glucose and lipids and its associated learning and memory impairments in NAFLD rats. | 2021 | Details |
| A01321 | 34788612 | Cell Rep | TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment. | 2021 | Details |
| A01336 | 34785385 | Clin Res Hepatol Gastroenterol | Trans-anethole attenuates diet-induced nonalcoholic steatohepatitis through suppressing TGF-β-mediated fibrosis. | 2021 | Details |
| A01339 | 34783554 | J Agric Food Chem | Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition. | 2021 | Details |
| A01341 | 34783091 | J Hum Nutr Diet | The Dietary Inflammatory Index and hepatic health in the US adult population. | 2021 | Details |
| A01343 | 34781143 | Biomed Pharmacother | Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction. | 2021 | Details |
| A01344 | 34780785 | Exp Cell Res | MicroRNA-22 inhibition promotes the development of atherosclerosis via targeting interferon regulator factor 5. | 2021 | Details |
| A01345 | 34780166 | Chem Res Toxicol | Differential Roles of Water-Insoluble and Water-Soluble Fractions of Diesel Exhaust Particles in the Development of Adverse Health Effects Due to Chronic Instillation of Diesel Exhaust Particles. | 2021 | Details |
| A01352 | 34778099 | Front Cell Infect Microbiol | Gut Microbiota, Glucose, Lipid, and Water-Electrolyte Metabolism in Children With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01356 | 34777255 | Front Endocrinol (Lausanne) | Emerging Roles of T Cells in the Pathogenesis of Nonalcoholic Steatohepatitis and Hepatocellular Carcinoma. | 2021 | Details |
| A01357 | 34776827 | Food Nutr Res | Weissella cibaria MG5285 and Lactobacillus reuteri MG5149 attenuated fat accumulation in adipose and hepatic steatosis in high-fat diet-induced C57BL/6J obese mice. | 2021 | Details |
| A01365 | 34774104 | Trials | Effects of naringenin supplementation in overweight/obese patients with non-alcoholic fatty liver disease: study protocol for a randomized double-blind clinical trial. | 2021 | Details |
| A01377 | 34769060 | Int J Mol Sci | Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases. | 2021 | Details |
| A01379 | 34768813 | Int J Mol Sci | The Ameliorative Effects of Saikosaponin in Thioacetamide-Induced Liver Injury and Non-Alcoholic Fatty Liver Disease in Mice. | 2021 | Details |