Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00741 | 34982494 | J Intern Med | Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice. | 2022 | Details |
| A00744 | 34981470 | Adv Exp Med Biol | The Effect of Herbal Medicine and Natural Bioactive Compounds on Plasma Adiponectin: A Clinical Review. | 2021 | Details |
| A00748 | 34981123 | Biosci Rep | Tandem mass tag-based proteomics analysis of type 2 diabetes mellitus with non-alcoholic fatty liver disease in mice treated with acupuncture. | 2022 | Details |
| A00749 | 34981106 | Food Funct | Supplementation with cyanidin and delphinidin mitigates high fat diet-induced endotoxemia and associated liver inflammation in mice. | 2022 | Details |
| A00750 | 34980714 | J Nutr Sci Vitaminol (Tokyo) | Fasting, Nutrition and Weight Loss: An Approach to Refine Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00758 | 34978141 | Obes Rev | Human microbiome and metabolic health: An overview of systematic reviews. | 2022 | Details |
| A00764 | 34977118 | Front Nutr | Lactational High Fat Diet in Mice Causes Insulin Resistance and NAFLD in Male Offspring Which Is Partially Rescued by Maternal Metformin Treatment. | 2021 | Details |
| A00765 | 34975333 | Int J Biol Sci | Implication of the hepatokine, fibrinogen-like protein 1 in liver diseases, metabolic disorders and cancer: The need to harness its full potential. | 2022 | Details |
| A00768 | 34974284 | Nutrition | Serum concentration of fatty acids in children with obesity and nonalcoholic fatty liver disease. | 2021 | Details |
| A00769 | 34974159 | Mol Metab | CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing. | 2021 | Details |
| A00787 | 34966475 | Oxid Med Cell Longev | Structural and Functional Modulation of Gut Microbiota by Jiangzhi Granules during the Amelioration of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00804 | 34959990 | Nutrients | Dietary Composition and Its Association with Newly Diagnosed Nonalcoholic Fatty Liver Disease and Insulin Resistance. | 2021 | Details |
| A00805 | 34959901 | Nutrients | Role and Treatment of Insulin Resistance in Patients with Chronic Kidney Disease: A Review. | 2021 | Details |
| A00806 | 34959760 | Nutrients | Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study. | 2021 | Details |
| A00808 | 34959747 | Nutrients | High-Fructose, High-Fat Diet Alters Muscle Composition and Fuel Utilization in a Juvenile Iberian Pig Model of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00818 | 34957498 | Diabetes | Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice. | 2021 | Details |
| A00819 | 34957487 | Diabetes | Active Brown Adipose Tissue is Associated With a Healthier Metabolic Phenotype in Obesity. | 2021 | Details |
| A00842 | 34950996 | Indian J Gastroenterol | Fetuin-A in newly detected type 2 diabetes mellitus as a marker of non-alcoholic fatty liver disease. | 2021 | Details |
| A00850 | 34948230 | Int J Mol Sci | It Is High Time Physicians Thought of Natural Products for Alleviating NAFLD. Is There Sufficient Evidence to Use Them? | 2021 | Details |
| A00861 | 34944728 | Biomedicines | Hepatokines and Non-Alcoholic Fatty Liver Disease: Linking Liver Pathophysiology to Metabolism. | 2021 | Details |
| A00865 | 34944682 | Biomedicines | Metabolic Associated Fatty Liver Disease in Children-From Atomistic to Holistic. | 2021 | Details |
| A00866 | 34944668 | Biomedicines | The Role of Physical Activity in Nonalcoholic and Metabolic Dysfunction Associated Fatty Liver Disease. | 2021 | Details |
| A00872 | 34943946 | Cells | Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese Ay Mice. | 2021 | Details |
| A00880 | 34943134 | Antioxidants (Basel) | Hepatoprotective Effect of Bee Bread in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Rats: Impact on Oxidative Stress and Inflammation. | 2021 | Details |
| A00895 | 34938205 | Front Physiol | Ectodysplasin A/Ectodysplasin A Receptor System and Their Roles in Multiple Diseases. | 2021 | Details |
| A00916 | 34931080 | Nat Metab | Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity. | 2021 | Details |
| A00926 | 34927282 | Drug Dev Res | Schisandrin B ameliorates non-alcoholic liver disease through anti-inflammation activation in diabetic mice. | 2021 | Details |
| A00938 | 34923950 | Curr Mol Pharmacol | Potential Natural Compounds for the Prevention and Treatment of Nonalcoholic Fatty Liver Disease: A Review on Molecular Mechanisms. | 2021 | Details |
| A00940 | 34923463 | Wiad Lek | INSULIN RESISTANCE AS AN INDICATOR OF DIFFERENTIATION FOR THE FORMATION OF RISK GROUPS FOR NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITHOUT TYPE 2 DIABETES MELLITUS, AS A PART OF ONTOLOGICAL MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE. | 2021 | Details |
| A00952 | 34921174 | Sci Rep | Elevated serum S14 levels are associated with more severe liver steatosis by ultrasonography. | 2021 | Details |
| A00956 | 34919684 | J Nutr | A Specifically Tailored Multistrain Probiotic and Micronutrient Mixture Affects Nonalcoholic Fatty Liver Disease-Related Markers in Patients with Obesity after Mini Gastric Bypass Surgery. | 2022 | Details |
| A00958 | 34919135 | JAMA Netw Open | Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials. | 2021 | Details |
| A00960 | 34918493 | Pediatr Obes | MicroRNAs as the promising markers of comorbidities in childhood obesity-A systematic review. | 2021 | Details |
| A00963 | 34917917 | Metabol Open | Emerging roles for stress kinase p38 and stress hormone fibroblast growth factor 21 in NAFLD development. | 2021 | Details |
| A00976 | 34914039 | Indian J Gastroenterol | Endoscopic sleeve gastroplasty - minimally invasive treatment for non-alcoholic fatty liver disease and obesity. | 2021 | Details |
| A00986 | 34909847 | Arq Gastroenterol | MONOCYTE/HDL RATIO IN NON-ALCOHOLIC HEPATIC STEATOSIS. | 2021 | Details |
| A00988 | 34909410 | Psoriasis (Auckl) | Non-Alcoholic Fatty Liver Disease (NAFLD) in Patients with Psoriasis: A Review of the Hepatic Effects of Systemic Therapies. | 2021 | Details |
| A00992 | 34907906 | J Clin Invest | Dietary sugar restriction reduces hepatic de novo lipogenesis in boys with fatty liver disease. | 2021 | Details |
| A00998 | 34906902 | Biochem Biophys Res Commun | Obesity induced Ext1 reduction mediates the occurrence of NAFLD. | 2021 | Details |
| A01003 | 34905051 | J Clin Endocrinol Metab | Fibrogenesis marker PRO-C3 is higher in advanced liver fibrosis and improves in patients undergoing bariatric surgery. | 2022 | Details |
| A01004 | 34904966 | Am J Gastroenterol | Objectively Measured Physical Activity Is Inversely Associated With Nonalcoholic Fatty Liver Disease: The Rotterdam Study. | 2022 | Details |
| A01021 | 34901163 | Front Mol Biosci | The Role of Notch Signaling Pathway in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01022 | 34900816 | J Diabetes Metab Disord | The effects of high fructose fruits and honey on the serum level of metabolic factors and nonalcoholic fatty liver disease. | 2021 | Details |
| A01042 | 34893351 | Trends Pharmacol Sci | ER stress in obesity pathogenesis and management. | 2021 | Details |
| A01047 | 34890043 | Eur J Clin Invest | The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women. | 2022 | Details |
| A01051 | 34887672 | Diabetes Metab Syndr Obes | Upregulated lncRNA HCG18 in Patients with Non-Alcoholic Fatty Liver Disease and Its Regulatory Effect on Insulin Resistance. | 2021 | Details |
| A01053 | 34887631 | World J Gastroenterol | Non-alcoholic fatty liver disease in patients with intestinal, pulmonary or skin diseases: Inflammatory cross-talk that needs a multidisciplinary approach. | 2021 | Details |
| A01060 | 34884650 | Int J Mol Sci | Verification of the Impact of Blood Glucose Level on Liver Carcinogenesis and the Efficacy of a Dietary Intervention in a Spontaneous Metabolic Syndrome Model. | 2021 | Details |
| A01061 | 34884625 | Int J Mol Sci | Hypothyroidism-Associated Dyslipidemia: Potential Molecular Mechanisms Leading to NAFLD. | 2021 | Details |
| A01067 | 34881510 | Pediatr Obes | The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial. | 2021 | Details |
| A01074 | 34877910 | Expert Rev Gastroenterol Hepatol | Effects of probiotics on nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
| A01090 | 34871812 | Clin Gastroenterol Hepatol | Intensive Lifestyle Management Improves Steatosis and Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01097 | 34870138 | Metabol Open | Metabolic causes and consequences of nonalcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A01111 | 34866849 | J Clin Exp Hepatol | Tobacco, Cigarettes, and the Liver: The Smoking Gun. | 2021 | Details |
| A01114 | 34866842 | J Clin Exp Hepatol | Adipocytokines as Risk Factors for Development of Nonalcoholic Fatty Liver Disease in Children. | 2021 | Details |
| A01118 | 34863942 | Mol Metab | The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. | 2021 | Details |
| A01119 | 34863940 | Mol Metab | URAT1-selective inhibition ameliorates insulin resistance by attenuating diet-induced hepatic steatosis and brown adipose tissue whitening in mice. | 2021 | Details |
| A01135 | 34859497 | J Gastroenterol Hepatol | Low serum pancreatic amylase levels as a novel latent risk factor for colorectal adenoma in non-alcohol drinkers. | 2021 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01144 | 34856688 | Zhonghua Nei Ke Za Zhi | [Correlation between intrahepatic triglyceride content quantified by proton magnetic resonance spectroscopy and glucose metabolism]. | 2021 | Details |
| A01151 | 34853949 | Handb Exp Pharmacol | Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance. | 2021 | Details |
| A01152 | 34853313 | Nat Commun | GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity. | 2021 | Details |
| A01154 | 34850865 | Dis Model Mech | Concerted regulation of non-alcoholic fatty liver disease progression by microRNAs in apolipoprotein E-deficient mice. | 2021 | Details |
| A01156 | 34850445 | J Gastroenterol Hepatol | The microbial metabolome in metabolic-associated fatty liver disease. | 2021 | Details |
| A01159 | 34848984 | Diabetes Metab Syndr Obes | Effect of LncPVT1/miR-20a-5p on Lipid Metabolism and Insulin Resistance in NAFLD. | 2021 | Details |
| A01173 | 34841290 | Cell Rep Med | Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease. | 2021 | Details |
| A01174 | 34840719 | Ther Adv Endocrinol Metab | NAFLD in type 1 diabetes: overrated or underappreciated? | 2021 | Details |
| A01176 | 34840086 | J Diabetes Complications | First-degree family history of diabetes is associated with nonalcoholic fatty liver disease independent of glucose metabolic status. | 2021 | Details |
| A01183 | 34836332 | Nutrients | Impact of Genetic Polymorphism on Response to Therapy in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01192 | 34833467 | Medicina (Kaunas) | Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients. | 2021 | Details |
| A01195 | 34831031 | Cells | Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01198 | 34830360 | Int J Mol Sci | Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD. | 2021 | Details |
| A01202 | 34829926 | Biomedicines | Non-Alcoholic Fatty Liver Disease (NAFLD) and Potential Links to Depression, Anxiety, and Chronic Stress. | 2021 | Details |
| A01211 | 34828697 | Children (Basel) | Association between Hepatic Steatosis and Obstructive Sleep Apnea in Children and Adolescents with Obesity. | 2021 | Details |
| A01220 | 34823548 | J Transl Med | CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype. | 2021 | Details |
| A01224 | 34822647 | Vet Sci | Protective and Therapeutic Effects of Orlistat on Metabolic Syndrome and Oxidative Stress in High-Fat Diet-Induced Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) in Rats: Role on Nrf2 Activation. | 2021 | Details |
| A01233 | 34819792 | Saudi Pharm J | Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease. | 2021 | Details |
| A01237 | 34818080 | Metab Syndr Relat Disord | Increased Serum Pentraxin 3 Is Associated with Prediabetes and Type 2 Diabetes in Obese Patients with Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01243 | 34816009 | JGH Open | Risk factors of nonalcoholic fatty liver disease in lean body mass population: A systematic review and meta-analysis. | 2021 | Details |
| A01252 | 34814152 | Ann Nutr Metab | Inverse Association of Serum Adipsin with the Remission of Nonalcoholic Fatty-Liver Disease: A 3-Year Community-Based Cohort Study. | 2021 | Details |
| A01253 | 34813997 | Biomed Pharmacother | SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice. | 2021 | Details |
| A01256 | 34813496 | Physiol Int | Effect of vanillic acid and exercise training on fatty liver and insulin resistance in rats: Possible role of fibroblast growth factor 21 and autophagy. | 2021 | Details |
| A01260 | 34811578 | Handb Exp Pharmacol | NAFLD and NASH: The Metabolically Diseased Liver. | 2021 | Details |
| A01267 | 34808500 | Biochem Biophys Res Commun | Endoplasmic reticulum stress increases LECT2 expression via ATF4. | 2021 | Details |
| A01270 | 34808224 | J Pediatr | Comparison of the Triglyceride Glucose Index and Modified Triglyceride Glucose Indices to Predict Nonalcoholic Fatty Liver Disease in Youths. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01279 | 34803916 | Front Endocrinol (Lausanne) | Sestrin2 as a Potential Target for Regulating Metabolic-Related Diseases. | 2021 | Details |
| A01280 | 34803681 | Front Pharmacol | The Effects of Vitamin D Supplementation on Anthropometric and Biochemical Indices in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
| A01294 | 34798892 | BMC Complement Med Ther | Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial. | 2021 | Details |
| A01308 | 34794234 | Biomed Pharmacother | Saroglitazar and Hepano treatment offers protection against high fat high fructose diet induced obesity, insulin resistance and steatosis by modulating various class of hepatic and circulating lipids. | 2021 | Details |
| A01309 | 34794182 | Semin Liver Dis | The Neglected Role of Bile Duct Epithelial Cells in NASH. | 2021 | Details |
| A01318 | 34789138 | Curr Med Imaging | Evaluation of Aortic Distensibility in Patients with Nonalcoholic Fatty Liver using CT. | 2021 | Details |
| A01339 | 34783554 | J Agric Food Chem | Novel Sesquiterpene Glycoside from Loquat Leaf Alleviates Type 2 Diabetes Mellitus Combined with Nonalcoholic Fatty Liver Disease by Improving Insulin Resistance, Oxidative Stress, Inflammation, and Gut Microbiota Composition. | 2021 | Details |
| A01343 | 34781143 | Biomed Pharmacother | Carminic acid mitigates fructose-triggered hepatic steatosis by inhibition of oxidative stress and inflammatory reaction. | 2021 | Details |
| A01345 | 34780166 | Chem Res Toxicol | Differential Roles of Water-Insoluble and Water-Soluble Fractions of Diesel Exhaust Particles in the Development of Adverse Health Effects Due to Chronic Instillation of Diesel Exhaust Particles. | 2021 | Details |
| A01346 | 34780030 | Hepatol Int | Impact of non-alcoholic fatty liver disease on the risk of sarcopenia: a nationwide multicenter prospective study. | 2021 | Details |
| A01348 | 34779464 | Food Funct | MUFA in metabolic syndrome and associated risk factors: is MUFA the opposite side of the PUFA coin? | 2021 | Details |
| A01357 | 34776827 | Food Nutr Res | Weissella cibaria MG5285 and Lactobacillus reuteri MG5149 attenuated fat accumulation in adipose and hepatic steatosis in high-fat diet-induced C57BL/6J obese mice. | 2021 | Details |
| A01373 | 34771023 | Molecules | Zinc as a Drug for Wilson's Disease, Non-Alcoholic Liver Disease and COVID-19-Related Liver Injury. | 2021 | Details |
| A01374 | 34769488 | Int J Mol Sci | The Roles of Carbohydrate Response Element Binding Protein in the Relationship between Carbohydrate Intake and Diseases. | 2021 | Details |