Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A21695 | 25112833 | J Endocrinol | Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet. | 2014 | Details |
| A21698 | 25111123 | Nutrients | Dietary fructose reduction improves markers of cardiovascular disease risk in Hispanic-American adolescents with NAFLD. | 2014 | Details |
| A21734 | 25083081 | World J Gastroenterol | Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease. | 2014 | Details |
| A21738 | 25083077 | World J Gastroenterol | Translational approaches: from fatty liver to non-alcoholic steatohepatitis. | 2014 | Details |
| A21740 | 25080922 | Am J Physiol Gastrointest Liver Physiol | Decreasing mitochondrial fission alleviates hepatic steatosis in a murine model of nonalcoholic fatty liver disease. | 2014 | Details |
| A21759 | 25066109 | Diabetes Metab Res Rev | GLP-1 receptor agonists: effects on the progression of non-alcoholic fatty liver disease. | 2014 | Details |
| A21761 | 25064435 | J Hepatol | Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent. | 2014 | Details |
| A21766 | 25061559 | Mol Metab | ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload. | 2014 | Details |
| A21772 | 25057104 | Nutrients | Pinus densiflora Sieb. et Zucc. alleviates lipogenesis and oxidative stress during oleic acid-induced steatosis in HepG2 cells. | 2014 | Details |
| A21781 | 25048951 | J Hepatol | CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis. | 2014 | Details |
| A21785 | 25045618 | Curr Hepatol Rep | Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis. | 2014 | Details |
| A21786 | 25045415 | Oxid Med Cell Longev | Circulating levels of sirtuin 4, a potential marker of oxidative metabolism, related to coronary artery disease in obese patients suffering from NAFLD, with normal or slightly increased liver enzymes. | 2014 | Details |
| A21792 | 25043405 | Hepatology | Fructose leads to hepatic steatosis in zebrafish that is reversed by mechanistic target of rapamycin (mTOR) inhibition. | 2014 | Details |
| A21800 | 25035929 | Biochem Biophys Res Commun | PKCδ regulates hepatic triglyceride accumulation and insulin signaling in Lepr(db/db) mice. | 2014 | Details |
| A21801 | 25035342 | Arterioscler Thromb Vasc Biol | Links between ectopic fat and vascular disease in humans. | 2014 | Details |
| A21815 | 25026599 | Biochem Pharmacol | Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice. | 2014 | Details |
| A21818 | 25024598 | World J Gastroenterol | Nonalcoholic fatty liver disease and cardiovascular disease. | 2014 | Details |
| A21823 | 25024593 | World J Gastroenterol | Modern approach to the clinical management of non-alcoholic fatty liver disease. | 2014 | Details |
| A21848 | 25003670 | Turk J Gastroenterol | Nonalcoholic fatty liver disease: diagnosis, pathogenesis, and management. | 2014 | Details |
| A21850 | 25003023 | FEBS Open Bio | Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis. | 2014 | Details |
| A21852 | 25000850 | Clin Nutr | Novel pathway for iron deficiency in pediatric non-alcoholic steatohepatitis. | 2014 | Details |
| A21854 | 24998389 | Sci Rep | Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model. | 2014 | Details |
| A21857 | 24995693 | Hepatology | The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice. | 2014 | Details |
| A21875 | 24987492 | Oxid Med Cell Longev | Serum oxidative stress markers and lipidomic profile to detect NASH patients responsive to an antioxidant treatment: a pilot study. | 2014 | Details |
| A21879 | 24983359 | PLoS One | L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway. | 2014 | Details |
| A21890 | 24976430 | Nutrition | Effect of vitamin E supplementation on aminotransferase levels in patients with NAFLD, NASH, and CHC: results from a meta-analysis. | 2014 | Details |
| A21891 | 24976401 | Biochem Biophys Res Commun | NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease. | 2014 | Details |
| A21905 | 24969468 | Anal Bioanal Chem | In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS. | 2014 | Details |
| A21906 | 24968846 | Nan Fang Yi Ke Da Xue Xue Bao | [Therapeutic effect of saxagliptin in rat models of nonalcoholic fatty liver and type 2 diabetes]. | 2014 | Details |
| A21908 | 24968737 | Endocrine | Does vitamin D improve liver enzymes, oxidative stress, and inflammatory biomarkers in adults with non-alcoholic fatty liver disease? A randomized clinical trial. | 2014 | Details |
| A21913 | 24966607 | World J Gastroenterol | Effects of resveratrol and other polyphenols in hepatic steatosis. | 2014 | Details |
| A21920 | 24966582 | World J Gastroenterol | Pathogenesis and significance of hepatitis C virus steatosis: an update on survival strategy of a successful pathogen. | 2014 | Details |
| A21930 | 24958099 | Mol Cell Biol | Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance. | 2014 | Details |
| A21942 | 24949725 | Am J Med Sci | Oxidative balance in lymphocytes from patients with nonalcoholic steatohepatitis. | 2014 | Details |
| A21956 | 24937020 | Eur J Pharmacol | Treatment with baicalein attenuates methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats. | 2014 | Details |
| A21966 | 24927063 | Mol Med Rep | Radix Hedysari polysaccharide suppresses lipid metabolism dysfunction in a rat model of non‑alcoholic fatty liver disease via adenosine monophosphate‑activated protein kinase pathway activation. | 2014 | Details |
| A21980 | 24917551 | Gut | Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis. | 2014 | Details |
| A22016 | 24887549 | Int J Biol Macromol | Hypoglycemic and hepatoprotective effects of polysaccharides from Artemisia sphaerocephala Krasch seeds. | 2014 | Details |
| A22018 | 24884574 | BMC Gastroenterol | Fast food diet with CCl4 micro-dose induced hepatic-fibrosis--a novel animal model. | 2014 | Details |
| A22030 | 24866317 | Rev Med Inst Mex Seguro Soc | [Nonalcoholic fatty liver disease in children]. | 2014 | Details |
| A22031 | 24865256 | Dig Dis Sci | Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet. | 2014 | Details |
| A22034 | 24861470 | Environ Toxicol | Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice. | 2014 | Details |
| A22038 | 24858832 | PLoS One | β-Cryptoxanthin alleviates diet-induced nonalcoholic steatohepatitis by suppressing inflammatory gene expression in mice. | 2014 | Details |
| A22039 | 24857839 | Arch Biochem Biophys | Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis. | 2014 | Details |
| A22040 | 24857364 | J Agric Food Chem | Garlic essential oil protects against obesity-triggered nonalcoholic fatty liver disease through modulation of lipid metabolism and oxidative stress. | 2014 | Details |
| A22059 | 24847414 | Oxid Med Cell Longev | The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes in vitro. | 2014 | Details |
| A22061 | 24845607 | J Hepatol | Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice. | 2014 | Details |
| A22074 | 24837835 | Int J Mol Sci | Role of mitochondria in nonalcoholic fatty liver disease. | 2014 | Details |
| A22081 | 24830635 | Horm Metab Res | Additive effects of nicotine and high-fat diet on hepatocellular apoptosis in mice: involvement of caspase 2 and inducible nitric oxide synthase-mediated intrinsic pathway signaling. | 2014 | Details |
| A22083 | 24830559 | Int J Mol Sci | Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation. | 2014 | Details |
| A22089 | 24829591 | Hepat Mon | Nonalcoholic Fatty liver disease/non-alcoholic steatohepatitis in childhood: endocrine-metabolic "mal-programming". | 2014 | Details |
| A22092 | 24827819 | Mol Nutr Food Res | Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice. | 2014 | Details |
| A22101 | 24821109 | Biochem Pharmacol | Cyanidin-3-O-β-glucoside protects primary mouse hepatocytes against high glucose-induced apoptosis by modulating mitochondrial dysfunction and the PI3K/Akt pathway. | 2014 | Details |
| A22108 | 24815820 | Food Chem Toxicol | Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin. | 2014 | Details |
| A22114 | 24811405 | Appl Microbiol Biotechnol | Preventing non-alcoholic fatty liver disease through Lactobacillus johnsonii BS15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice. | 2014 | Details |
| A22117 | 24803983 | Oxid Med Cell Longev | BL153 partially prevents high-fat diet induced liver damage probably via inhibition of lipid accumulation, inflammation, and oxidative stress. | 2014 | Details |
| A22146 | 24789994 | Am J Physiol Regul Integr Comp Physiol | Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity. | 2014 | Details |
| A22148 | 24788149 | PLoS One | Lipotoxic effect of p21 on free fatty acid-induced steatosis in L02 cells. | 2014 | Details |
| A22151 | 24786095 | Int J Mol Sci | Molecular mechanisms and new treatment strategies for non-alcoholic steatohepatitis (NASH). | 2014 | Details |
| A22161 | 30736156 | Expert Rev Endocrinol Metab | Insulin-like growth factors (IGF-I and -II): new actors in the development of non-alcoholic fatty liver disease. | 2014 | Details |
| A22189 | 24758604 | BMC Gastroenterol | NOX2-generated oxidative stress is associated with severity of ultrasound liver steatosis in patients with non-alcoholic fatty liver disease. | 2014 | Details |
| A22190 | 24758559 | Biochem J | Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice. | 2014 | Details |
| A22195 | 24754177 | Zhongguo Zhong Yao Za Zhi | [Effect of pure total flavonoids from citrus on hepatic SIRT1/PGC-1alpha pathway in mice with NASH]. | 2014 | Details |
| A22220 | 24743120 | Georgian Med News | [Mechanisms of formation and progression of non-alcoholic fatty liver disease in type 2 diabetics]. | 2014 | Details |
| A22222 | 24742471 | J Nutr Biochem | Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases. | 2014 | Details |
| A22231 | 24737902 | Postgrad Med J | Republished: Non-alcoholic fatty liver disease: non-invasive investigation and risk stratification. | 2014 | Details |
| A22233 | 24735863 | J Ethnopharmacol | Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells. | 2014 | Details |
| A22241 | 24729784 | Gastroenterol Res Pract | Chronic kidney disease and nonalcoholic Fatty liver disease-is there a link? | 2014 | Details |
| A22256 | 24716162 | J Tradit Complement Med | Recent advances in the herbal treatment of non-alcoholic Fatty liver disease. | 2013 | Details |
| A22259 | 24712752 | J Med Food | Antioxidant properties of proanthocyanidins attenuate carbon tetrachloride (CCl4)-induced steatosis and liver injury in rats via CYP2E1 regulation. | 2014 | Details |
| A22264 | 24707151 | World J Gastroenterol | Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population. | 2014 | Details |
| A22265 | 24706428 | J Pediatr Endocrinol Metab | Serum paraoxonase activity and oxidative stress and their relationship with obesity-related metabolic syndrome and non-alcoholic fatty liver disease in obese children and adolescents. | 2014 | Details |
| A22271 | 24702768 | FEBS J | Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease. | 2014 | Details |
| A22276 | 24696627 | Hepat Med | A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of events. | 2014 | Details |
| A22287 | 24689911 | Metab Syndr Relat Disord | Regular exercise coupled to diet regimen accelerates reduction of hepatic steatosis and associated pathological conditions in nonalcoholic fatty liver disease. | 2014 | Details |
| A22312 | 24672550 | Int J Cell Biol | An Intimate Relationship between ROS and Insulin Signalling: Implications for Antioxidant Treatment of Fatty Liver Disease. | 2014 | Details |
| A22345 | 24649902 | Liver Int | Genetic variations of superoxide dismutase 2 and cytochrome P450 2E1 in non-alcoholic steatohepatitis. | 2014 | Details |
| A22369 | 24634500 | J Lipid Res | c9,t11-Conjugated linoleic acid ameliorates steatosis by modulating mitochondrial uncoupling and Nrf2 pathway. | 2014 | Details |
| A22386 | 24627311 | Drug Saf | Potential approaches to ameliorate hepatic fat accumulation seen with MTP inhibition. | 2014 | Details |
| A22392 | 24622832 | J Physiol Pharmacol | Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up. | 2014 | Details |
| A22393 | 24622831 | J Physiol Pharmacol | Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. | 2014 | Details |
| A22396 | 24621397 | Liver Int | Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)? | 2014 | Details |
| A22415 | 24597775 | Antioxid Redox Signal | RORα decreases oxidative stress through the induction of SOD2 and GPx1 expression and thereby protects against nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A22424 | 24587658 | World J Gastroenterol | Diet high in fructose leads to an overexpression of lipocalin-2 in rat fatty liver. | 2014 | Details |
| A22429 | 24587650 | World J Gastroenterol | Clinical approaches to non-alcoholic fatty liver disease. | 2014 | Details |
| A22473 | 24532325 | J Sci Food Agric | Antihyperglycemic, hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model. | 2014 | Details |
| A22482 | 24523491 | J Nutr | Bitter gourd inhibits the development of obesity-associated fatty liver in C57BL/6 mice fed a high-fat diet. | 2014 | Details |
| A22486 | 24520789 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Study on the mechanism of action of total saponins of Panax notoginseng in ameliorating oxidative stress and insulin resistance in rats fed with high fat diet]. | 2014 | Details |
| A22524 | 24492282 | Lab Invest | Increased expression of c-Jun in nonalcoholic fatty liver disease. | 2014 | Details |
| A22529 | 24489777 | PLoS One | Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats. | 2014 | Details |
| A22537 | 24481563 | J Physiol Biochem | Effects of binge ethanol on lipid homeostasis and oxidative stress in a rat model of nonalcoholic fatty liver disease. | 2014 | Details |
| A22555 | 24464605 | Hepatology | Reduced adiponectin signaling due to weight gain results in nonalcoholic steatohepatitis through impaired mitochondrial biogenesis. | 2014 | Details |
| A22556 | 24464211 | Dig Dis Sci | OxNASH score correlates with histologic features and severity of nonalcoholic fatty liver disease. | 2014 | Details |
| A22563 | 24461315 | Nutr Res | Cinnamon may have therapeutic benefits on lipid profile, liver enzymes, insulin resistance, and high-sensitivity C-reactive protein in nonalcoholic fatty liver disease patients. | 2013 | Details |
| A22565 | 24460502 | Gynecol Endocrinol | Nonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women. | 2014 | Details |
| A22573 | 24454937 | PLoS One | Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis. | 2014 | Details |
| A22583 | 24445049 | J Nutr Biochem | Sesame oil mitigates nutritional steatohepatitis via attenuation of oxidative stress and inflammation: a tale of two-hit hypothesis. | 2013 | Details |
| A22596 | 24428929 | BMC Genomics | Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle. | 2014 | Details |
| A22622 | 24402518 | Genes Nutr | A case-control study on the effect of metabolic gene polymorphisms, nutrition, and their interaction on the risk of non-alcoholic fatty liver disease. | 2014 | Details |
| A22632 | 24396406 | Exp Ther Med | Effects of glutamine on oxidative stress and nuclear factor-κB expression in the livers of rats with nonalcoholic fatty liver disease. | 2013 | Details |