Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A13619 | 29872017 | J Biosci | Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease. | 2018 | Details |
| A13627 | 29864915 | Biomed Pharmacother | Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. | 2018 | Details |
| A13628 | 29864682 | J Nutr Biochem | Non-alcoholic fatty liver disease severity and metabolic complications in obese children: impact of omega-3 fatty acids. | 2018 | Details |
| A13635 | 29860222 | Biomed Pharmacother | Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway. | 2018 | Details |
| A13637 | 29860108 | Atherosclerosis | Obesity and incidence of diabetes: Effect of absence of metabolic syndrome, insulin resistance, inflammation and fatty liver. | 2018 | Details |
| A13638 | 29860102 | J Nutr Biochem | Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet. | 2018 | Details |
| A13640 | 29859544 | Br J Nutr | Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function? | 2018 | Details |
| A13648 | 29857146 | Clin Gastroenterol Hepatol | Evaluations of Lifestyle, Dietary, and Pharmacologic Treatments for Pediatric Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2018 | Details |
| A13654 | 29854716 | Can J Gastroenterol Hepatol | Predictive Value of Adiposity Level, Metabolic Syndrome, and Insulin Resistance for the Risk of Nonalcoholic Fatty Liver Disease Diagnosis in Obese Children. | 2018 | Details |
| A13655 | 29854715 | Can J Gastroenterol Hepatol | Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children. | 2018 | Details |
| A13659 | 29852170 | Biochem Biophys Res Commun | Suppression of NF-κB activation by PDLIM2 restrains hepatic lipogenesis and inflammation in high fat diet induced mice. | 2018 | Details |
| A13663 | 29849912 | Oxid Med Cell Longev | The Essential Element Manganese, Oxidative Stress, and Metabolic Diseases: Links and Interactions. | 2018 | Details |
| A13664 | 29849623 | Int J Endocrinol | Fatty Liver as a Potential Surrogate for Waist Circumference in the Diagnosis of Metabolic Syndrome: A Population-Based Study among Chinese Adults. | 2018 | Details |
| A13666 | 29848284 | Microrna | Serum miR-29a and miR-122 as Potential Biomarkers for Non-Alcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13678 | 29844386 | Nat Commun | The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. | 2018 | Details |
| A13679 | 29844096 | Diabetes Care | Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars. | 2018 | Details |
| A13682 | 29843404 | Medicines (Basel) | Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13687 | 29805535 | Exp Ther Med | The therapeutic effects of bee venom on some metabolic and antioxidant parameters associated with HFD-induced non-alcoholic fatty liver in rats. | 2018 | Details |
| A13690 | 29804360 | Zhonghua Gan Zang Bing Za Zhi | [Effect of aerobic exercise and resistance exercise in improving non-alcoholic fatty liver disease: a randomized controlled trial]. | 2018 | Details |
| A13693 | 29803897 | Clin Chim Acta | Uric acid and cardiovascular disease. | 2018 | Details |
| A13695 | 29803210 | Neuro Endocrinol Lett | Shall we diagnose metabolic syndrome in adolescents? | 2018 | Details |
| A13700 | 29802399 | Sci Rep | Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis. | 2018 | Details |
| A13701 | 29802129 | Diabetes | Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13710 | 29797516 | Eur J Clin Invest | Exercising the hepatobiliary-gut axis. The impact of physical activity performance. | 2018 | Details |
| A13714 | 29795358 | Acta Pharmacol Sin | Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice. | 2018 | Details |
| A13717 | 29793999 | Diabetes | The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. | 2018 | Details |
| A13723 | 29791184 | Child Obes | A Narrative Review of Medical and Genetic Risk Factors among Children Age 5 and Younger with Severe Obesity. | 2018 | Details |
| A13724 | 29790582 | Hepatology | Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents. | 2018 | Details |
| A13726 | 29788220 | Endocrinology | Obstructive Sleep Apnea Syndrome and Metabolic Diseases. | 2018 | Details |
| A13736 | 29785076 | World J Gastroenterol | Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease. | 2018 | Details |
| A13738 | 29783682 | Diseases | Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases. | 2018 | Details |
| A13756 | 29772784 | Nutrients | Capsaicin in Metabolic Syndrome. | 2018 | Details |
| A13766 | 29766802 | Curr Drug Targets | Endoplasmic Reticulum Stress Related Molecular Mechanisms in Nonalcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13769 | 29765460 | Arch Med Sci | The role of intestinal microbiota in the pathogenesis of NAFLD: starting points for intervention. | 2016 | Details |
| A13770 | 29765172 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | Dietary sucrose regulates the expression of the Cd36 gene in hepatic tissue of rats with obesity and Non Alcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13772 | 29764990 | Sci Signal | IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. | 2018 | Details |
| A13792 | 29752404 | J Biol Chem | Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. | 2018 | Details |
| A13799 | 29749571 | J Gastroenterol | Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients. | 2018 | Details |
| A13805 | 29747118 | J Nutr Biochem | Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice. | 2018 | Details |
| A13819 | 29743560 | Cell Death Differ | Caspases in metabolic disease and their therapeutic potential. | 2018 | Details |
| A13839 | 29733805 | J Pediatr (Rio J) | IL-17A, MCP-1, CCR-2, and ABCA1 polymorphisms in children with non-alcoholic fatty liver disease. | 2018 | Details |
| A13843 | 29729191 | Hepatology | Caspase Recruitment Domain Protein 6 Protects Against Hepatic Steatosis and Insulin Resistance by Suppressing Apoptosis Signal-Regulating Kinase 1. | 2018 | Details |
| A13849 | 29728363 | Diabetes | Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes. | 2018 | Details |
| A13854 | 29725371 | Exp Ther Med | Analyses of risk factors for polycystic ovary syndrome complicated with non-alcoholic fatty liver disease. | 2018 | Details |
| A13857 | 29723898 | Horm Metab Res | The Relationship Between Liver Enzymes and Insulin Resistance in Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13867 | 29719598 | Oncotarget | Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver. | 2018 | Details |
| A13872 | 29717275 | Int J Obes (Lond) | Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers. | 2018 | Details |
| A13873 | 29717162 | Sci Rep | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. | 2018 | Details |
| A13876 | 29713279 | Front Pharmacol | Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation. | 2018 | Details |
| A13896 | 29704818 | Cytokine | Serum C1q/TNF-related protein 9 is not related to nonalcoholic fatty liver disease. | 2018 | Details |
| A13898 | 29704259 | Hepatology | TRUSS Exacerbates NAFLD Development by Promoting IκBα Degradation in Mice. | 2018 | Details |
| A13908 | 29698567 | Hepatology | Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6. | 2018 | Details |
| A13916 | 29696060 | J Med Life | Nonalcoholic fatty liver disease: epidemiology, pathogenesis and therapeutic implications. | 2018 | Details |
| A13918 | 29693586 | Nutrients | Ellagic Acid Alleviates Hepatic Oxidative Stress and Insulin Resistance in Diabetic Female Rats. | 2018 | Details |
| A13931 | 29683979 | Eur J Gastroenterol Hepatol | Lifestyle interventions for patients with nonalcoholic fatty liver disease: a network meta-analysis. | 2018 | Details |
| A13949 | 29674209 | Steroids | Possible mechanisms underlying fatty liver in a rat model of male hypogonadism: A protective role for testosterone. | 2018 | Details |
| A13962 | 29670844 | Adv Pharm Bull | The Eeffect of Metformin Combined with Calcium-Vitamin D3 Against Diet-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13966 | 29666152 | J Endocrinol | Phenylmethimazole abrogates diet-induced inflammation, glucose intolerance and NAFLD. | 2018 | Details |
| A13970 | 29665034 | Hepatology | Metabolic Features of Nonalcoholic Fatty Liver (NAFL) in Obese Adolescents: Findings From a Multiethnic Cohort. | 2018 | Details |
| A13975 | 29662003 | Int J Mol Sci | PPAR Agonists and Metabolic Syndrome: An Established Role? | 2018 | Details |
| A13984 | 29657020 | Clin Res Hepatol Gastroenterol | Helicobacter pylori infection aggravates diet-induced nonalcoholic fatty liver in mice. | 2018 | Details |
| A13992 | 29654490 | Mol Neurobiol | Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. | 2018 | Details |
| A13998 | 29652564 | J Am Coll Nutr | Examining the Relationship Between Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome in Nondiabetic Subjects. | 2018 | Details |
| A13999 | 29651819 | J Korean Med Sci | Biochemical Predictors of Early Onset Non-Alcoholic Fatty Liver Disease in Young Children with Obesity. | 2018 | Details |
| A14007 | 29641459 | Molecules | An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A14009 | 29636553 | Hypertens Res | The role of the angiotensin II type I receptor blocker telmisartan in the treatment of non-alcoholic fatty liver disease: a brief review. | 2018 | Details |
| A14012 | 29634665 | Eur J Gastroenterol Hepatol | Evaluation of postprandial hypoglycemia in patients with nonalcoholic fatty liver disease by oral glucose tolerance testing and continuous glucose monitoring. | 2018 | Details |
| A14013 | 29634314 | Am J Physiol Endocrinol Metab | Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis. | 2018 | Details |
| A14022 | 29631096 | Biochim Biophys Acta Mol Cell Biol Lipids | Genetic variation in human carboxylesterase CES1 confers resistance to hepatic steatosis. | 2018 | Details |
| A14028 | 29628274 | Trends Pharmacol Sci | Macrophage-Targeted Therapeutics for Metabolic Disease. | 2018 | Details |
| A14030 | 29626628 | Free Radic Biol Med | Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance. | 2018 | Details |
| A14041 | 29620197 | Mol Med Rep | Identification of key genes in non‑alcoholic fatty liver disease progression based on bioinformatics analysis. | 2018 | Details |
| A14042 | 29620148 | Int J Mol Med | Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS. | 2018 | Details |
| A14043 | 29619530 | Diabetologia | Can targeting ANGPTL proteins improve glucose tolerance? | 2018 | Details |
| A14046 | 29615042 | Lipids Health Dis | Higher non-HDL-cholesterol to HDL-cholesterol ratio linked with increased nonalcoholic steatohepatitis. | 2018 | Details |
| A14052 | 29609136 | Cytokine | Fetuin-B links nonalcoholic fatty liver disease to type 2 diabetes via inducing insulin resistance: Association and path analyses. | 2018 | Details |
| A14053 | 29608898 | Eur J Pharmacol | Canagliflozin protects against non-alcoholic steatohepatitis in type-2 diabetic rats through zinc alpha-2 glycoprotein up-regulation. | 2018 | Details |
| A14056 | 29608255 | Liver Int | Twenty-five-year trajectories of insulin resistance and pancreatic β-cell response and diabetes risk in nonalcoholic fatty liver disease. | 2018 | Details |
| A14057 | 29607802 | Public Health Nutr | Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes. | 2018 | Details |
| A14062 | 29604480 | Atherosclerosis | Nonalcoholic fatty liver disease and advanced fibrosis are associated with left ventricular diastolic dysfunction. | 2018 | Details |
| A14071 | 29602794 | Diabetes Care | Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A14072 | 29602237 | J Cell Mol Med | NEFA-induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non-alcoholic steatohepatitis. | 2018 | Details |
| A14073 | 29601997 | Contemp Clin Trials | Effectiveness of a carbohydrate restricted diet to treat non-alcoholic fatty liver disease in adolescents with obesity: Trial design and methodology. | 2018 | Details |
| A14081 | 29599925 | Oncotarget | A porcine placental extract prevents steatohepatitis by suppressing activation of macrophages and stellate cells in mice. | 2018 | Details |
| A14086 | 29595666 | Medicine (Baltimore) | Components of metabolic syndrome increase the risk of mortality in nonalcoholic fatty liver disease (NAFLD). | 2018 | Details |
| A14088 | 29594435 | Eur J Nutr | Higher serum carotenoids associated with improvement of non-alcoholic fatty liver disease in adults: a prospective study. | 2018 | Details |
| A14091 | 29593573 | Front Physiol | Rho, a Fraction From Rhodiola crenulate, Ameliorates Hepatic Steatosis in Mice Models. | 2018 | Details |
| A14092 | 29592806 | J Biomed Sci | β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway. | 2018 | Details |
| A14094 | 31089541 | J Obes Metab Syndr | Nonalcoholic Fatty Liver Disease and Abdominal Fat Accumulation According to Vitamin D Status in Patients with Type 2 Diabetes. | 2018 | Details |
| A14095 | 29590379 | J Clin Endocrinol Metab | Increased Plasma Proneurotensin Levels Identify NAFLD in Adults With and Without Type 2 Diabetes. | 2018 | Details |
| A14096 | 29590099 | PLoS Med | Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database. | 2018 | Details |
| A14100 | 29587769 | Reprod Biol Endocrinol | Circulating osteopontin and its association with liver fat content in non-obese women with polycystic ovary syndrome: a case control study. | 2018 | Details |
| A14101 | 29584615 | J Pediatr Endocrinol Metab | Metabolic and genetic markers' associations with elevated levels of alanine aminotransferase in adolescents. | 2018 | Details |
| A14102 | 29584449 | Crit Rev Food Sci Nutr | Efficacy of synbiotic supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials: Synbiotic supplementation and NAFLD. | 2018 | Details |
| A14105 | 29580823 | Mol Cell Endocrinol | GW0742 (PPAR-beta agonist) attenuates hepatic endoplasmic reticulum stress by improving hepatic energy metabolism in high-fat diet fed mice. | 2018 | Details |
| A14115 | 29575149 | J Cell Biochem | Exercise decreases CLK2 in the liver of obese mice and prevents hepatic fat accumulation. | 2018 | Details |
| A14116 | 29575055 | J Cell Biochem | MicroRNA-190b regulates lipid metabolism and insulin sensitivity by targeting IGF-1 and ADAMTS9 in non-alcoholic fatty liver disease. | 2018 | Details |
| A14118 | 29574933 | Clin Exp Pharmacol Physiol | The association of serum FGF23 and non-alcoholic fatty liver disease is independent of vitamin D in type 2 diabetes patients. | 2018 | Details |
| A14124 | 29573006 | Hepatology | Ubiquitin-Specific Protease 4 Is an Endogenous Negative Regulator of Metabolic Dysfunctions in Nonalcoholic Fatty Liver Disease in Mice. | 2018 | Details |
| A14128 | 29572342 | J Pharmacol Exp Ther | Protectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 Expression. | 2018 | Details |