Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25482 | 21781943 | J Hepatol | High fructose feeding induces copper deficiency in Sprague-Dawley rats: a novel mechanism for obesity related fatty liver. | 2011 | Details |
| A25501 | 21764273 | Nutr Metab Cardiovasc Dis | Obesity and metabolic syndrome: potential benefit from specific nutritional components. | 2011 | Details |
| A25502 | 21764223 | Med Hypotheses | Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease. | 2011 | Details |
| A25507 | 21756849 | J Hepatol | The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies. | 2011 | Details |
| A25510 | 21755261 | Braz J Med Biol Res | Effect of silybin on high-fat-induced fatty liver in rats. | 2011 | Details |
| A25533 | 21740407 | Br J Pharmacol | Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis. | 2012 | Details |
| A25543 | 21733326 | Br J Nutr | Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress. | 2011 | Details |
| A25544 | 21733302 | Br J Nutr | Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases. | 2011 | Details |
| A25550 | 21725512 | J Gastrointestin Liver Dis | Predictive factors for nonalcoholic steatohepatitis (NASH) in patients with nonalcoholic fatty liver disease (NAFLD). | 2011 | Details |
| A25553 | 21718726 | J Hepatol | Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target. | 2011 | Details |
| A25582 | 21690266 | J Lipid Res | Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. | 2011 | Details |
| A25587 | 21684478 | Arab J Gastroenterol | Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin. | 2011 | Details |
| A25607 | 21655948 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2011 | Details |
| A25610 | 21649947 | Ned Tijdschr Geneeskd | [Treatment of non-alcoholic fatty liver disease]. | 2011 | Details |
| A25611 | 21649732 | J Gastroenterol Hepatol | Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. | 2012 | Details |
| A25633 | 21621638 | Biochim Biophys Acta | Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats. | 2011 | Details |
| A25634 | 21620948 | Toxicol In Vitro | Cellular glutathione in fatty liver in vitro models. | 2011 | Details |
| A25641 | 21612059 | Vnitr Lek | [Steatosis and steatohepatitis in diabetic patient]. | 2011 | Details |
| A25657 | 21570964 | Exp Mol Pathol | A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A25671 | 21562784 | Dig Dis Sci | Fatty liver is associated with recurrent bacterial infections independent of metabolic syndrome. | 2011 | Details |
| A25673 | 21561340 | Metab Syndr Relat Disord | Oxidative stress is activated by free fatty acids in cultured human hepatocytes. | 2011 | Details |
| A25681 | 21556019 | Nat Rev Endocrinol | Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. | 2011 | Details |
| A25683 | 21549113 | Eur J Pharmacol | Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease. | 2011 | Details |
| A25688 | 21543212 | J Nutr Biochem | Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes. | 2011 | Details |
| A25699 | 21525818 | Med Sci Monit | SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease. | 2011 | Details |
| A25715 | 21514287 | Clin Chim Acta | The role of oxidative stress in non-alcoholic steatohepatitis. | 2011 | Details |
| A25720 | 21508207 | J Nutr | Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. | 2011 | Details |
| A25722 | 21504583 | Lipids Health Dis | High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway. | 2011 | Details |
| A25740 | 21489294 | Lipids Health Dis | Protective effect of whey proteins against nonalcoholic fatty liver in rats. | 2011 | Details |
| A25757 | 21476921 | Expert Rev Gastroenterol Hepatol | Organelle dysfunction in hepatitis C virus-associated steatosis: anything to learn from nonalcoholic steatohepatitis? | 2011 | Details |
| A25758 | 21476920 | Expert Rev Gastroenterol Hepatol | Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease. | 2011 | Details |
| A25760 | 21476918 | Expert Rev Gastroenterol Hepatol | Mitochondrial dysfunction in nonalcoholic steatohepatitis. | 2011 | Details |
| A25764 | 21476914 | Expert Rev Gastroenterol Hepatol | Inflammation in nonalcoholic steatohepatitis. | 2011 | Details |
| A25765 | 21476913 | Expert Rev Gastroenterol Hepatol | Fibrogenesis in nonalcoholic steatohepatitis. | 2011 | Details |
| A25779 | 21464822 | Lab Invest | Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice. | 2011 | Details |
| A25801 | 21445622 | Eur J Nutr | Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats. | 2011 | Details |
| A25813 | 21434863 | Curr HIV Res | Non-alcoholic fatty liver disease in HIV infection associated with altered hepatic fatty acid composition. | 2011 | Details |
| A25816 | 21429837 | Clin Res Hepatol Gastroenterol | Lack of association of GSTT1 and GSTP1 genes methylation and their expression profiles with risk of NAFLD in a sample of Iranian patients. | 2011 | Details |
| A25850 | 21395631 | Aliment Pharmacol Ther | Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. | 2011 | Details |
| A25859 | 21382273 | J Biol Regul Homeost Agents | Circulating levels of cytochrome C, gamma-glutamyl transferase, triglycerides and unconjugated bilirubin in overweight/obese patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25866 | 21378565 | Curr Opin Lipidol | Lipidomics is providing new insight into the metabolic syndrome and its sequelae. | 2011 | Details |
| A25872 | 21372165 | Am J Physiol Gastrointest Liver Physiol | Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats. | 2011 | Details |
| A25887 | 21352073 | Expert Opin Emerg Drugs | Treatment of non-alcoholic fatty liver disease with focus on emerging drugs. | 2011 | Details |
| A25894 | 21348181 | G Ital Cardiol (Rome) | [Non-alcoholic fatty liver disease: a new challenge for cardiologists]. | 2010 | Details |
| A25897 | 21346097 | J Nutr | PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liver. | 2011 | Details |
| A25911 | 21334394 | J Hepatol | Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease. | 2011 | Details |
| A25920 | 21327395 | Cell Tissue Res | Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation. | 2011 | Details |
| A25938 | 21299150 | Acta Gastroenterol Belg | Dietary lipids and NAFLD: suggestions for improved nutrition. | 2011 | Details |
| A25958 | 21266239 | Methods Enzymol | Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease. | 2011 | Details |
| A25959 | 21265881 | J Gastroenterol Hepatol | Plasma reactive carbonyl species levels and risk of non-alcoholic fatty liver disease. | 2011 | Details |
| A25974 | 21249309 | Biol Res | Cytoprotective and suicidal signaling in oxidative stress. | 2010 | Details |
| A25976 | 21246004 | World J Gastroenterol | Potential efficacy of ginger as a natural supplement for nonalcoholic fatty liver disease. | 2011 | Details |
| A25980 | 21240660 | Obes Surg | Hepatic expression of adiponectin receptors increases with non-alcoholic fatty liver disease progression in morbid obesity in correlation with glutathione peroxidase 1. | 2011 | Details |
| A25981 | 21240032 | Pancreas | Effect of different obesogenic diets on pancreatic histology in Ossabaw miniature swine. | 2011 | Details |
| A25988 | 21233280 | Am J Physiol Gastrointest Liver Physiol | Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice. | 2011 | Details |
| A25997 | 21225151 | Arq Gastroenterol | Experimental induction of steatosis in different tissues after the ingestion of a carbohydrate-rich diet: effect on the liver, on the heart and on indicators of oxidation. | 2011 | Details |
| A25999 | 21224501 | J Physiol Pharmacol | The pilot study of 3-month course of melatonin treatment of patients with nonalcoholic steatohepatitis: effect on plasma levels of liver enzymes, lipids and melatonin. | 2010 | Details |
| A26004 | 21218508 | Diabetes Metab Res Rev | Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia. | 2011 | Details |
| A26006 | 21216209 | Endocrinol Nutr | [Fatty liver and its clinical management in obese adolescents]. | 2011 | Details |
| A26011 | 21206006 | Dis Markers | Association of hypoadiponectinemia with hypoglutathionemia in NAFLD subjects with and without type 2 diabetes. | 2010 | Details |
| A26026 | 21191681 | Indian J Gastroenterol | Nonalcoholic fatty liver disease in India - a lot done, yet more required! | 2010 | Details |
| A26055 | 21160946 | World J Hepatol | Current status and agenda in the diagnosis of nonalcoholic steatohepatitis in Japan. | 2010 | Details |
| A26061 | 21150132 | Drug Metab Pharmacokinet | Progression of alcoholic and non-alcoholic steatohepatitis: common metabolic aspects of innate immune system and oxidative stress. | 2010 | Details |
| A26073 | 21145823 | J Hepatol | Galectin-3 ablation protects mice from diet-induced NASH: a major scavenging role for galectin-3 in liver. | 2010 | Details |
| A26085 | 21128705 | Antioxid Redox Signal | Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease. | 2011 | Details |
| A26095 | 26190482 | Clin J Gastroenterol | The latest idea in NAFLD/NASH pathogenesis. | 2010 | Details |
| A26105 | 21091931 | J Dig Dis | Epidemiology of the metabolic syndrome in the USA. | 2011 | Details |
| A26113 | 21073649 | Liver Int | Angiogenesis in chronic liver disease and its complications. | 2010 | Details |
| A26117 | 21072890 | World J Gastroenterol | Pediatric nonalcoholic fatty liver disease: overview with emphasis on histology. | 2010 | Details |
| A26118 | 21071306 | Orv Hetil | [Fatty liver and global cardiometabolic risk]. | 2010 | Details |
| A26165 | 20969475 | Antioxid Redox Signal | Redox balance in the pathogenesis of nonalcoholic fatty liver disease: mechanisms and therapeutic opportunities. | 2011 | Details |
| A26175 | 20955971 | Best Pract Res Clin Gastroenterol | Nonalcoholic fatty liver disease. | 2010 | Details |
| A26190 | 20938947 | Hepatology | Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice. | 2010 | Details |
| A26196 | 20929443 | Clin Sci (Lond) | Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C. | 2011 | Details |
| A26199 | 20923528 | J Diabetes | Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance. | 2009 | Details |
| A26243 | 20845385 | Biotechnol J | Hepatoprotective effect of oleuropein in mice: mechanisms uncovered by gene expression profiling. | 2010 | Details |
| A26260 | 20818484 | Int J Mol Med | Oxidative stress parameters in paediatric non-alcoholic fatty liver disease. | 2010 | Details |
| A26264 | 20815776 | Free Radic Res | Palmitate protects hepatocytes from oxidative stress and triacylglyceride accumulation by stimulation of nitric oxide synthesis in the presence of high glucose and insulin concentration. | 2010 | Details |
| A26271 | 20805291 | Drug Metab Dispos | Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. | 2010 | Details |
| A26310 | 20664312 | Korean J Gastroenterol | [Nonalcoholic fatty liver disease]. | 2010 | Details |
| A26316 | 20658156 | J Gastroenterol | Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26318 | 20655714 | J Nutr Biochem | Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice. | 2010 | Details |
| A26321 | 20653983 | Lipids Health Dis | Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats. | 2010 | Details |
| A26335 | 20631297 | J Lipid Res | Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2010 | Details |
| A26336 | 20629985 | J Cell Mol Med | High fat diet-induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia. | 2010 | Details |
| A26357 | 20600152 | Life Sci | Hyperglycemia-induced mitochondrial alterations in liver. | 2010 | Details |
| A26360 | 20594230 | J Gastroenterol Hepatol | Oxidative stress and regulation of anti-oxidant enzymes in cytochrome P4502E1 transgenic mouse model of non-alcoholic fatty liver. | 2010 | Details |
| A26364 | 20584230 | Int J Clin Pract | Pharmacological and non-pharmacological treatment of non-alcoholic fatty liver disease. | 2010 | Details |
| A26365 | 20582634 | Sleep Breath | An experimental research on chronic intermittent hypoxia leading to liver injury. | 2010 | Details |
| A26372 | 20576005 | Obes Rev | Melanin and melanogenesis in adipose tissue: possible mechanisms for abating oxidative stress and inflammation? | 2011 | Details |
| A26376 | 20569523 | Proc Nutr Soc | The importance of fatty liver disease in clinical practice. | 2010 | Details |
| A26382 | 20557969 | J Hepatol | Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis. | 2010 | Details |
| A26386 | 20553760 | Prog Lipid Res | Biosynthesis and bioavailability of long-chain polyunsaturated fatty acids in non-alcoholic fatty liver disease. | 2010 | Details |
| A26388 | 20548286 | Lab Invest | Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. | 2010 | Details |
| A26393 | 20531177 | Curr Opin Clin Nutr Metab Care | Nonalcoholic fatty liver disease in children. | 2010 | Details |
| A26400 | 20518077 | World J Gastroenterol | Soft drinks consumption and nonalcoholic fatty liver disease. | 2010 | Details |
| A26401 | 20513351 | Biochem Biophys Res Commun | Chromium attenuates high-fat diet-induced nonalcoholic fatty liver disease in KK/HlJ mice. | 2010 | Details |
| A26411 | 20501438 | Am J Physiol Gastrointest Liver Physiol | Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation. | 2009 | Details |
| A26419 | 20491641 | Curr Med Chem | Targeting mitochondria: a new promising approach for the treatment of liver diseases. | 2010 | Details |
| A26421 | 20487204 | J Pharm Pharmacol | Effects of Eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitis. | 2010 | Details |