Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A27226 | 18950580 | Med Sci (Paris) | [Can the hyperactivity of lipogenesis cause hepatic steatosis? A role for ChREBP]. | 2008 | Details |
| A27227 | 18949388 | Int J Mol Med | The significance of differences in fatty acid metabolism between obese and non-obese patients with non-alcoholic fatty liver disease. | 2008 | Details |
| A27228 | 18948971 | Obesity (Silver Spring) | Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content. | 2008 | Details |
| A27229 | 18947828 | Atherosclerosis | Association between nonalcoholic fatty liver disease and carotid intima-media thickness according to the presence of metabolic syndrome. | 2008 | Details |
| A27230 | 18945255 | Aliment Pharmacol Ther | Clinical trial: pilot study of metformin for the treatment of non-alcoholic steatohepatitis. | 2008 | Details |
| A27231 | 18942340 | Pol Merkur Lekarski | [Non invasive markers of non-alcoholic steatohepatitis]. | 2008 | Details |
| A27233 | 18939388 | Cleve Clin J Med | Nonalcoholic fatty liver disease: a manifestation of the metabolic syndrome. | 2008 | Details |
| A27234 | 18938777 | Scand J Gastroenterol | Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet. | 2008 | Details |
| A27235 | 18936912 | Naunyn Schmiedebergs Arch Pharmacol | A role for atorvastatin and insulin combination in protecting from liver injury in a model of type 2 diabetes with hyperlipidemia. | 2008 | Details |
| A27236 | 18929493 | Trends Endocrinol Metab | Insulin resistance, inflammation, and non-alcoholic fatty liver disease. | 2008 | Details |
| A27237 | 18929425 | J Hepatol | A rodent model of NASH with cirrhosis, oval cell proliferation and hepatocellular carcinoma. | 2008 | Details |
| A27238 | 18926950 | J Formos Med Assoc | Disease progression in a patient with nonalcoholic steatohepatitis. | 2008 | Details |
| A27239 | 18926681 | J Nutr Biochem | Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease. | 2008 | Details |
| A27240 | 18925303 | Can J Gastroenterol | Soft drink consumption linked with fatty liver in the absence of traditional risk factors. | 2008 | Details |
| A27241 | 18922966 | Pharmacol Rev | Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. | 2008 | Details |
| A27242 | 18854760 | J Hypertens | Nonalcoholic fatty liver disease, adiponectin and insulin resistance in dipper and nondipper essential hypertensive patients. | 2008 | Details |
| A27243 | 18853997 | J Gastroenterol Hepatol | A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. | 2008 | Details |
| A27244 | 18853984 | Am J Gastroenterol | Association between non-alcoholic fatty liver disease and cardiovascular disease: a first message should pass. | 2008 | Details |
| A27245 | 18852641 | J Pediatr Gastroenterol Nutr | Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease. | 2008 | Details |
| A27246 | 18848602 | Biochim Biophys Acta | Co-factors in liver disease: the role of HFE-related hereditary hemochromatosis and iron. | 2008 | Details |
| A27247 | 18844098 | Zhonghua Yi Xue Za Zhi | [Relationship of liver fat content to insulin resistance and metabolic syndrome]. | 2008 | Details |
| A27248 | 18839055 | Acta Diabetol | Insulin resistance and exercise capacity in male children and adolescents with non-alcholic fatty liver disease. | 2008 | Details |
| A27249 | 18839053 | Acta Diabetol | The effect of metformin on leptin in obese patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease. | 2008 | Details |
| A27250 | 18836616 | J Gastrointestin Liver Dis | Prevalence and associated risk factors of non-alcoholic fatty liver disease in hospitalized patients. | 2008 | Details |
| A27251 | 18835952 | Diabetes Care | Serum adipocyte fatty acid-binding protein levels are associated with nonalcoholic fatty liver disease in type 2 diabetic patients. | 2008 | Details |
| A27252 | 18831772 | BMC Gastroenterol | Risk factors associated with non-alcoholic fatty liver disease in subjects from primary care units. A case-control study. | 2008 | Details |
| A27253 | 18826952 | J Biol Chem | Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes. | 2008 | Details |
| A27254 | 18825466 | J Gastrointest Surg | Routine liver biopsy to screen for nonalcoholic fatty liver disease (NAFLD) during cholecystectomy for gallstone disease: is it justified? | 2008 | Details |
| A27255 | 18824034 | Prog Lipid Res | Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). | 2008 | Details |
| A27256 | 18823438 | J Gastroenterol Hepatol | Marked elevation of serum mitochondrion-derived markers in mild models of non-alcoholic steatohepatitis in rats. | 2008 | Details |
| A27257 | 26193649 | Clin J Gastroenterol | Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case. | 2008 | Details |
| A27258 | 18822121 | BMC Mol Biol | Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet. | 2008 | Details |
| A27259 | 18821470 | Curr Opin Investig Drugs | The endoplasmic reticulum as a potential therapeutic target in nonalcoholic fatty liver disease. | 2008 | Details |
| A27260 | 18820647 | Nat Genet | Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. | 2008 | Details |
| A27261 | 18819037 | Scand J Gastroenterol | Utility of quantitative 99mTc-phytate scintigraphy to diagnose early-stage non-alcoholic steatohepatitis. | 2009 | Details |
| A27262 | 18813860 | Int J Mol Med | Therapeutic effect of ARBs on insulin resistance and liver injury in patients with NAFLD and chronic hepatitis C: a pilot study. | 2008 | Details |
| A27263 | 18807134 | J Gastroenterol | Transient elastography for measurement of liver stiffness measurement can detect early significant hepatic fibrosis in Japanese patients with viral and nonviral liver diseases. | 2008 | Details |
| A27264 | 18806722 | Pediatr Endocrinol Rev | The inflammatory process of adipose tissue. | 2008 | Details |
| A27265 | 18804555 | Contemp Clin Trials | Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design. | 2008 | Details |
| A27266 | 18796674 | Radiology | Liver steatosis: investigation of opposed-phase T1-weighted liver MR signal intensity loss and visceral fat measurement as biomarkers. | 2008 | Details |
| A27267 | 18795706 | Hepatogastroenterology | Serum gamma-glutamyltranspeptidase distinguishes non-alcoholic fatty liver disease at high risk. | 2009 | Details |
| A27268 | 18793002 | J Rheumatol | Liver involvement in systemic lupus erythematosus: case review of 40 patients. | 2008 | Details |
| A27269 | 18791133 | Exp Biol Med (Maywood) | Soy protein isolate reduces hepatosteatosis in yellow Avy/a mice without altering coat color phenotype. | 2008 | Details |
| A27271 | 18789715 | Cytokine | Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease. | 2008 | Details |
| A27272 | 18782535 | Zhong Xi Yi Jie He Xue Bao | [Effects of puerarin on expressions of leptin receptor mRNA, phosphorylated Janus kinase 2/phosphorylated signal transducers and activators of transcription 3 proteins in the liver of rats with non-alcoholic fatty liver]. | 2008 | Details |
| A27273 | 18782455 | BMC Gastroenterol | Resveratrol inhibits nonalcoholic fatty liver disease in rats. | 2008 | Details |
| A27274 | 18778590 | Curr Diab Rep | Nutrition and nonalcoholic fatty liver disease in children. | 2008 | Details |
| A27275 | 18774133 | Atherosclerosis | The severity of nonalcoholic fatty liver disease is associated with increased cardiovascular risk in a large cohort of non-obese Asian subjects. | 2008 | Details |
| A27276 | 18772365 | Am J Physiol Gastrointest Liver Physiol | Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent. | 2008 | Details |
| A27277 | 18769764 | Biol Res | Effects of weight loss on liver and erythrocyte polyunsaturated fatty acid pattern and oxidative stress status in obese patients with non-alcoholic fatty liver disease. | 2008 | Details |
| A27278 | 18765303 | Mitochondrion | Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression. | 2008 | Details |
| A27279 | 18763311 | J Zhejiang Univ Sci B | Relationship between alanine aminotransferase levels and metabolic syndrome in nonalcoholic fatty liver disease. | 2008 | Details |
| A27280 | 18762907 | Diabetologia | Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon? | 2008 | Details |
| A27281 | 18760271 | Clin Chim Acta | A preliminary investigation of the association between haptoglobin polymorphism, serum ferritin concentration and fatty liver disease. | 2008 | Details |
| A27282 | 18753993 | Ann Hepatol | Leptin in nonalcoholic fatty liver disease. | 2009 | Details |
| A27283 | 18753987 | Ann Hepatol | Imaging techniques for assessing hepatic fat content in nonalcoholic fatty liver disease. | 2009 | Details |
| A27285 | 18752564 | J Gastroenterol Hepatol | Animal models of NASH: getting both pathology and metabolic context right. | 2008 | Details |
| A27286 | 18752470 | Biochem J | High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo. | 2009 | Details |
| A27287 | 18752331 | Hepatology | Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes. | 2008 | Details |
| A27288 | 18752326 | Hepatology | Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice. | 2008 | Details |
| A27289 | 18728159 | J Clin Endocrinol Metab | Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss. | 2008 | Details |
| A27290 | 18721166 | Pediatr Diabetes | Treatment of non-alcoholic fatty liver disease with metformin versus lifestyle intervention in insulin-resistant adolescents. | 2008 | Details |
| A27291 | 18720744 | Srp Arh Celok Lek | [Elevated body mass index and fatty liver]. | 2008 | Details |
| A27292 | 18719669 | Obesity (Silver Spring) | Effect of endurance exercise on hepatic lipid content, enzymes, and adiposity in men and women. | 2008 | Details |
| A27293 | 18713300 | J Gastroenterol Hepatol | Polymorphism of human leptin receptor gene is associated with type 2 diabetic patients complicated with non-alcoholic fatty liver disease in China. | 2008 | Details |
| A27294 | 18713296 | J Gastroenterol Hepatol | Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease. | 2008 | Details |
| A27295 | 18710604 | Br J Nutr | Flaxseed oil prevents trans-10, cis-12-conjugated linoleic acid-induced insulin resistance in mice. | 2008 | Details |
| A27296 | 18710430 | Liver Int | Hepatitis C virus infection enhances insulin resistance induced by visceral fat accumulation. | 2008 | Details |
| A27297 | 18708987 | South Med J | Metabolic syndrome as a risk factor for nonalcoholic fatty liver disease. | 2008 | Details |
| A27298 | 18702346 | Pol Merkur Lekarski | [Non-alcoholic fatty liver disease--new view]. | 2008 | Details |
| A27299 | 18698683 | World J Gastroenterol | Blood F2-isoprostanes are significantly associated with abnormalities of lipid status in rats with steatosis. | 2008 | Details |
| A27300 | 18698674 | World J Gastroenterol | Chronic liver disease in Aboriginal North Americans. | 2008 | Details |
| A27301 | 18694396 | Clin Sci (Lond) | Phenotyping murine models of non-alcoholic fatty liver disease through metabolic profiling of intact liver tissue. | 2009 | Details |
| A27302 | 18689359 | Am J Clin Nutr | Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents. | 2008 | Details |
| A27303 | 18684196 | Am J Gastroenterol | Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study. | 2008 | Details |
| A27304 | 18684170 | Am J Gastroenterol | The epidemiology of newly diagnosed chronic liver disease in gastroenterology practices in the United States: results from population-based surveillance. | 2008 | Details |
| A27305 | 18684130 | Hepatol Res | Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. | 2008 | Details |
| A27306 | 18683746 | Zhonghua Fu Chan Ke Za Zhi | [Prevalence of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome: a case-control study]. | 2008 | Details |
| A27307 | 18683048 | Dig Dis Sci | HFE gene mutations, serum ferritin level, transferrin saturation, and their clinical correlates in a Korean population. | 2008 | Details |
| A27308 | 18682312 | J Hepatol | Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease. | 2008 | Details |
| A27309 | 18674764 | Atherosclerosis | Investigation of hepatic gluconeogenesis pathway in non-diabetic Asian Indians with non-alcoholic fatty liver disease using in vivo ((31)P) phosphorus magnetic resonance spectroscopy. | 2008 | Details |
| A27310 | 18672640 | J Med Assoc Thai | Hepatic cytochrome P450 2E1 activity in nonalcoholic fatty liver disease. | 2008 | Details |
| A27311 | 18672311 | J Hepatol | Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review. | 2008 | Details |
| A27312 | 18667766 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | [Non-alcoholic fatty liver, high sensitivity C reactive protein and insulin resistance]. | 2008 | Details |
| A27313 | 18664346 | Zhong Xi Yi Jie He Xue Bao | [Effects of Yiqi Sanju Formula on non-alcoholic fatty liver disease: a randomized controlled trial]. | 2008 | Details |
| A27314 | 18662168 | Clin Sci (Lond) | Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations. | 2008 | Details |
| A27315 | 18661429 | Scand J Gastroenterol | Insulin resistance and metabolic syndrome in chronic liver diseases: old entities with new implications. | 2009 | Details |
| A27316 | 18654951 | Int J Vitam Nutr Res | Non-alcoholic fatty liver disease in overweight children and its relationship with retinol serum levels. | 2008 | Details |
| A27317 | 18654934 | Scand J Gastroenterol | Chitosan ameliorates the severity of steatohepatitis induced by high fat diet in rats. | 2008 | Details |
| A27318 | 18654060 | Postgrad Med | Nonalcoholic fatty liver disease: hepatic manifestation of obesity and the metabolic syndrome. | 2008 | Details |
| A27319 | 18652898 | Pharmacol Res | Defining therapeutic targets for liver fibrosis: exploiting the biology of inflammation and repair. | 2008 | Details |
| A27320 | 18648737 | J Gastroenterol | Liver diseases and metabolic syndrome. | 2008 | Details |
| A27321 | 18647533 | Zhonghua Gan Zang Bing Za Zhi | [The application of proton magnetic resonance spectroscopy and computerized tomography in evaluating nonalcoholic fatty liver disease]. | 2008 | Details |
| A27322 | 18647236 | Liver Int | Apnoeic-hypopnoeic episodes during obstructive sleep apnoea are associated with histological nonalcoholic steatohepatitis. | 2008 | Details |
| A27323 | 18647235 | Liver Int | Non-alcoholic fatty liver disease and its association with obesity, insulin resistance and increased serum levels of C-reactive protein in Hispanics. | 2008 | Details |
| A27324 | 18642663 | Zhonghua Yu Fang Yi Xue Za Zhi | [Epidemiological survey of the association between non alcoholic fatty liver disease and metabolic syndrome in civil servants of Chongqing city]. | 2008 | Details |
| A27325 | 18641190 | J Nutr | Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake. | 2008 | Details |
| A27326 | 18640473 | Clin Ther | Metformin use in children with nonalcoholic fatty liver disease: an open-label, 24-month, observational pilot study. | 2008 | Details |
| A27327 | 18640006 | Nutrition | High-fat diet: a trigger of non-alcoholic steatohepatitis? Preliminary findings in obese subjects. | 2008 | Details |
| A27328 | 18638391 | BMC Cancer | AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease. | 2008 | Details |