Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A18552 | 27061435 | J Cell Mol Med | miR-149 controls non-alcoholic fatty liver by targeting FGF-21. | 2016 | Details |
| A18575 | 27051596 | BBA Clin | Implication of hepatokines in metabolic disorders and cardiovascular diseases. | 2016 | Details |
| A18582 | 27048250 | Diabetologia | Hepatic glucose and lipid metabolism. | 2016 | Details |
| A18586 | 27045805 | Sci Rep | Mechanistically linked serum miRNAs distinguish between drug induced and fatty liver disease of different grades. | 2016 | Details |
| A18597 | 27040510 | Biochim Biophys Acta | Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH. | 2016 | Details |
| A18605 | 27038448 | Dig Dis Sci | Global Epidemiology of Nonalcoholic Fatty Liver Disease and Perspectives on US Minority Populations. | 2016 | Details |
| A18625 | 27028410 | Liver Int | Lipid disorder and intrahepatic renin-angiotensin system activation synergistically contribute to non-alcoholic fatty liver disease. | 2016 | Details |
| A18639 | 27019638 | Int J Biol Sci | Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury. | 2016 | Details |
| A18642 | 27018382 | Biochem Biophys Res Commun | Protective effects of Lactobacillus rhamnosus GG against dyslipidemia in high-fat diet-induced obese mice. | 2016 | Details |
| A18647 | 27016407 | Toxicol Lett | Mancozeb, a fungicide routinely used in agriculture, worsens nonalcoholic fatty liver disease in the human HepG2 cell model. | 2016 | Details |
| A18648 | 27016281 | J Hepatol | DKK3 expression in hepatocytes defines susceptibility to liver steatosis and obesity. | 2016 | Details |
| A18677 | 27002331 | PLoS One | Effect of Octreotide on Hepatic Steatosis in Diet-Induced Obesity in Rats. | 2016 | Details |
| A18680 | 27001282 | Nutr Res | Opuntia ficus-indica seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet-fed mice. | 2015 | Details |
| A18698 | 26993969 | Med Sci Monit | Sleep Apnea and Fatty Liver Are Coupled Via Energy Metabolism. | 2016 | Details |
| A18701 | 26993042 | J Mol Cell Biol | Discovering a critical transition state from nonalcoholic hepatosteatosis to nonalcoholic steatohepatitis by lipidomics and dynamical network biomarkers. | 2016 | Details |
| A18705 | 26989875 | Mol Nutr Food Res | Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system. | 2016 | Details |
| A18708 | 26988666 | Cancer Discov | CD4+ T Cell Loss Drives NAFLD Progression to Hepatocellular Carcinoma. | 2016 | Details |
| A18709 | 26986083 | Int J Mol Med | Adipose tissue-derived stem cells promote the reversion of non-alcoholic fatty liver disease: An in vivo study. | 2016 | Details |
| A18713 | 26984711 | Arch Toxicol | Prolonged exposure to low-dose microcystin induces nonalcoholic steatohepatitis in mice: a systems toxicology study. | 2016 | Details |
| A18729 | 26980291 | J Invest Surg | Fetuin A is a Predictor of Liver Fat in Preoperative Patients with Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18742 | 26976285 | BMC Gastroenterol | Comparative experimental investigation on the efficacy of mono- and multiprobiotic strains in non-alcoholic fatty liver disease prevention. | 2016 | Details |
| A18743 | 26976243 | Am J Pathol | Hepatic Oncostatin M Receptor β Regulates Obesity-Induced Steatosis and Insulin Resistance. | 2016 | Details |
| A18747 | 26972505 | J Ethnopharmacol | Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress. | 2016 | Details |
| A18752 | 26971824 | Gastroenterology | Perspectives on Treatment for Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18755 | 26970305 | Biochem Biophys Res Commun | Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress. | 2016 | Details |
| A18761 | 26962056 | Toxicol Sci | Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice. | 2016 | Details |
| A18762 | 26962021 | Biochim Biophys Acta | Nuclear receptors and nonalcoholic fatty liver disease. | 2016 | Details |
| A18767 | 26959059 | Nutrients | The Potential Protective Action of Vitamin D in Hepatic Insulin Resistance and Pancreatic Islet Dysfunction in Type 2 Diabetes Mellitus. | 2016 | Details |
| A18773 | 26952573 | Exp Gerontol | β2-Adrenergic receptor ablation modulates hepatic lipid accumulation and glucose tolerance in aging mice. | 2016 | Details |
| A18779 | 26947067 | Cell Rep | The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction. | 2016 | Details |
| A18787 | 26941577 | Int J Med Sci | Palmitate-induced Regulation of PPARγ via PGC1α: a Mechanism for Lipid Accumulation in the Liver in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18799 | 26934227 | Nature | NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. | 2016 | Details |
| A18802 | 26932748 | Sci Rep | Involvement of splenic iron accumulation in the development of nonalcoholic steatohepatitis in Tsumura Suzuki Obese Diabetes mice. | 2016 | Details |
| A18804 | 26932533 | Int J Food Sci Nutr | Medium-chain fatty acid reduces lipid accumulation by regulating expression of lipid-sensing genes in human liver cells with steatosis. | 2016 | Details |
| A18807 | 26928243 | Gastroenterology | Pathogenesis of Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18816 | 26923972 | Clin Calcium | [Non-alcoholic fatty liver disease (NAFLD) /non-alcoholic steatohepatitis (NASH) and nutrition]. | 2016 | Details |
| A18828 | 26915720 | Gen Physiol Biophys | Hepatoprotective potential of zingerone against nonalcoholic fatty liver disease in rats fed with fructose-enriched diet. | 2016 | Details |
| A18830 | 26914024 | PLoS One | White Pitaya (Hylocereus undatus) Juice Attenuates Insulin Resistance and Hepatic Steatosis in Diet-Induced Obese Mice. | 2016 | Details |
| A18840 | 26909306 | Mol Metab | Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. | 2015 | Details |
| A18850 | 26903296 | Biochem Biophys Res Commun | Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice. | 2016 | Details |
| A18853 | 26901384 | Liver Int | Deregulated hepatic microRNAs underlie the association between non-alcoholic fatty liver disease and coronary artery disease. | 2016 | Details |
| A18856 | 26900108 | J Agric Food Chem | Ginger Essential Oil Ameliorates Hepatic Injury and Lipid Accumulation in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18860 | 26895665 | J Nutr Biochem | Liver-specific deletion of the signal transducer and activator of transcription 5 gene aggravates fatty liver in response to a high-fat diet in mice. | 2015 | Details |
| A18865 | 26894897 | Cell Mol Life Sci | Pathogenesis of nonalcoholic steatohepatitis. | 2016 | Details |
| A18874 | 26890260 | PLoS One | SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. | 2016 | Details |
| A18875 | 26890135 | Cell Death Dis | Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease. | 2016 | Details |
| A18887 | 26885088 | Int J Clin Exp Med | Serum osteocalcin levels are inversely associated with the presence of nonalcoholic fatty liver disease in patients with coronary artery disease. | 2015 | Details |
| A18888 | 26883384 | Sci Rep | Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis. | 2016 | Details |
| A18891 | 26882978 | Biochem Biophys Res Commun | Depletion of Rab32 decreases intracellular lipid accumulation and induces lipolysis through enhancing ATGL expression in hepatocytes. | 2016 | Details |
| A18895 | 26881239 | J Diabetes Res | Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in Apoe (-/-) Mice Fed with High-Fat Diet. | 2015 | Details |
| A18900 | 26880573 | J Hepatobiliary Pancreat Sci | Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a choline-deficient diet: a follow-up report on long-term effects of oxidative stress in non-alcoholic fatty liver disease. | 2016 | Details |
| A18909 | 26874076 | Gastroenterology | Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening. | 2016 | Details |
| A18910 | 26873633 | Biochim Biophys Acta | iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. | 2016 | Details |
| A18918 | 26870973 | Georgian Med News | [ADIPONECTIN AND A VIOLATION OF METABOLIC CONTROL AT DIFFERENT STAGES OF NONALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH TYPE 2 DIABETES]. | 2016 | Details |
| A18924 | 26868960 | Obesity (Silver Spring) | Normal weight dyslipidemia: Is it all about the liver? | 2016 | Details |
| A18930 | 26865652 | J Nutr | Dietary Broccoli Lessens Development of Fatty Liver and Liver Cancer in Mice Given Diethylnitrosamine and Fed a Western or Control Diet. | 2016 | Details |
| A18933 | 26861390 | Nutrients | Psoralea corylifolia L. Seed Extract Attenuates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced Obese Mice. | 2016 | Details |
| A18941 | 26858195 | J Pediatr | Amino Acid Metabolism is Altered in Adolescents with Nonalcoholic Fatty Liver Disease-An Untargeted, High Resolution Metabolomics Study. | 2016 | Details |
| A18953 | 26852528 | Vopr Pitan | [Genomic, proteomic and metabolomic predictors of nonalcoholic fatty liver disease development in obese patients. Part I]. | 2015 | Details |
| A18976 | 26838599 | Gut | Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. | 2016 | Details |
| A18983 | 26832365 | Lipids Health Dis | Fish oil alleviated high-fat diet-induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study. | 2016 | Details |
| A18992 | 26829204 | J Hepatol | Metabolic interplay between white, beige, brown adipocytes and the liver. | 2016 | Details |
| A18995 | 28871698 | Zhongguo Zhong Yao Za Zhi | [Effect of total flavones of hawthorn leafonon expression of COX-2/Nrf2 in liver of rats with nonalcoholic steatohepatitis]. | 2016 | Details |
| A18998 | 26826574 | Redox Biol | Effects of high fat diets on rodent liver bioenergetics and oxidative imbalance. | 2016 | Details |
| A19007 | 26822232 | Hepatology | Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. | 2016 | Details |
| A19031 | 26811286 | Int Rev Cell Mol Biol | Phosphatidylethanolamine Metabolism in Health and Disease. | 2015 | Details |
| A19033 | 26810228 | J Immunol | Subclinical-Dose Endotoxin Sustains Low-Grade Inflammation and Exacerbates Steatohepatitis in High-Fat Diet-Fed Mice. | 2016 | Details |
| A19038 | 26807955 | PLoS One | Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. | 2016 | Details |
| A19043 | 26806698 | J Pharm Pharmacol | Wild ginseng cambial meristematic cells ameliorate hepatic steatosis and mitochondrial dysfunction in high-fat diet-fed mice. | 2016 | Details |
| A19044 | 26806650 | Hepatology | Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice. | 2016 | Details |
| A19045 | 26805874 | Nutrients | Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes. | 2016 | Details |
| A19058 | 26794005 | J Gastroenterol | Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice. | 2016 | Details |
| A19084 | 26774456 | Biochem Pharmacol | Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer. | 2016 | Details |
| A19085 | 26773785 | Nutr Res | Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet to induce nonalcoholic fatty liver disease. | 2015 | Details |
| A19086 | 26773781 | Nutr Res | Chokeberry attenuates the expression of genes related to de novo lipogenesis in the hepatocytes of mice with nonalcoholic fatty liver disease. | 2015 | Details |
| A19087 | 26773359 | Environ Toxicol Pharmacol | Di(2-ethylhexyl) phthalate exacerbates non-alcoholic fatty liver in rats and its potential mechanisms. | 2015 | Details |
| A19139 | 26732252 | Sci Rep | Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. | 2016 | Details |
| A19146 | 26728273 | BMB Rep | The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities. | 2016 | Details |
| A19164 | 26718596 | Mol Med Rep | bZIP transmembrane transcription factor CREBH: Potential role in non-alcoholic fatty liver disease (Review). | 2015 | Details |
| A19169 | 30280553 | Eksp Klin Gastroenterol | [LIPID PROFILE AND LIVER DISEASES AMONG PATIENTS WITH MORBID OBESITY]. | 2018 | Details |
| A19176 | 29889442 | Eksp Klin Gastroenterol | THE ROLE OF BILE ACIDS IN THE REGULATION OF LIPID AND CARBOHYDRATE METABOLISM IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND DIABETES TYPE2. | 2018 | Details |
| A19178 | 29889391 | Eksp Klin Gastroenterol | NON-ALCOHOLIC FATTY LIVER DISEASE IN ELDERLY. | 2018 | Details |
| A19208 | 26703097 | Trends Endocrinol Metab | The Role of Cholesterol in the Pathogenesis of NASH. | 2015 | Details |
| A19213 | 26698881 | J Biol Chem | The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism. | 2015 | Details |
| A19214 | 26698665 | Free Radic Biol Med | Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development. | 2015 | Details |
| A19222 | 26695389 | Can J Physiol Pharmacol | Irisin levels in relation to metabolic and liver functions in Egyptian patients with metabolic syndrome. | 2015 | Details |
| A19226 | 26690419 | Int J Mol Sci | Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. | 2015 | Details |
| A19227 | 26690233 | J Clin Med | MicroRNAs in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19229 | 26687947 | Biochem Biophys Res Commun | Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis. | 2015 | Details |
| A19235 | 26681923 | Int J Biol Sci | A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis. | 2015 | Details |
| A19238 | 26679056 | Mol Nutr Food Res | Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet. | 2016 | Details |
| A19239 | 26678309 | BMC Gastroenterol | Deficiency of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat distribution. | 2015 | Details |
| A19257 | 26670228 | Int J Mol Sci | The Dipeptidyl Peptidase-4 Inhibitor Teneligliptin Attenuates Hepatic Lipogenesis via AMPK Activation in Non-Alcoholic Fatty Liver Disease Model Mice. | 2015 | Details |
| A19259 | 26668692 | World J Hepatol | Bile acid receptors and nonalcoholic fatty liver disease. | 2015 | Details |
| A19267 | 26666731 | J Ethnopharmacol | The hepatoprotective effect of the combination use of Fructus Schisandrae with statin--A preclinical evaluation. | 2015 | Details |
| A19271 | 26663351 | Hepatology | Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice. | 2016 | Details |
| A19272 | 26663034 | Acta Physiol (Oxf) | Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress. | 2015 | Details |
| A19282 | 26655953 | J Biol Chem | Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice. | 2015 | Details |
| A19288 | 26648452 | J Cell Mol Med | miR-212 downregulation contributes to the protective effect of exercise against non-alcoholic fatty liver via targeting FGF-21. | 2015 | Details |
| A19312 | 26634892 | Phytother Res | Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway. | 2015 | Details |