Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A13479 | 29956204 | Adv Exp Med Biol | Pathogenesis of NASH: How Metabolic Complications of Overnutrition Favour Lipotoxicity and Pro-Inflammatory Fatty Liver Disease. | 2018 | Details |
| A13488 | 29953011 | Medicine (Baltimore) | Prevalence and factors associated with nonalcoholic fatty pancreas disease and its severity in China. | 2018 | Details |
| A13492 | 29951362 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease: A Review of Anti-diabetic Pharmacologic Therapies. | 2018 | Details |
| A13493 | 29950116 | Expert Opin Investig Drugs | MSDC-0602K, a metabolic modulator directed at the core pathology of non-alcoholic steatohepatitis. | 2018 | Details |
| A13495 | 29948900 | Sci China Life Sci | Characteristics of fecal microbiota in non-alcoholic fatty liver disease patients. | 2018 | Details |
| A13499 | 29947156 | Phytother Res | Green tea as a safe alternative approach for nonalcoholic fatty liver treatment: A systematic review and meta-analysis of clinical trials. | 2018 | Details |
| A13500 | 29947103 | Eur J Clin Invest | Plasma lecithin:cholesterol acyltransferase and phospholipid transfer protein activity independently associate with nonalcoholic fatty liver disease. | 2018 | Details |
| A13501 | 29947044 | Clin Endocrinol (Oxf) | High Irisin levels in nondiabetic HIV-infected males are associated with insulin resistance, nonalcoholic fatty liver disease, and subclinical atherosclerosis. | 2018 | Details |
| A13503 | 29946426 | F1000Res | Recent advances in understanding and managing non-alcoholic fatty liver disease. | 2018 | Details |
| A13504 | 29945982 | J Endocrinol | INT-767 prevents NASH and promotes visceral fat brown adipogenesis and mitochondrial function. | 2018 | Details |
| A13512 | 29940269 | J Hepatol | Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease. | 2018 | Details |
| A13523 | 29931613 | Curr Diab Rep | The Gut Microbiome as a Target for the Treatment of Type 2 Diabetes. | 2018 | Details |
| A13525 | 29930810 | Biomed Rep | Efficacy of orlistat in non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2018 | Details |
| A13531 | 29928260 | Front Endocrinol (Lausanne) | Liver Enlargement Predicts Obstructive Sleep Apnea-Hypopnea Syndrome in Morbidly Obese Women. | 2018 | Details |
| A13539 | 29924632 | Am J Physiol Regul Integr Comp Physiol | Heat shock protein 72 regulates hepatic lipid accumulation. | 2018 | Details |
| A13540 | 29924135 | Braz J Med Biol Res | Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease. | 2018 | Details |
| A13541 | 29923211 | Andrologia | Beneficial effect of apple vinegar on reproductive parameters in male rat model of nonalcoholic fatty liver disease. | 2018 | Details |
| A13544 | 29921379 | J Biol Regul Homeost Agents | The involvement and mechanism of febuxostat in non-alcoholic fatty liver disease cells. | 2018 | Details |
| A13545 | 29920701 | Aliment Pharmacol Ther | Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B. | 2018 | Details |
| A13550 | 29915740 | J Family Med Prim Care | A study on the altered glycemic and lipid parameters and prevalence of insulin resistance in nonalcoholic fatty liver disease. | 2022 | Details |
| A13551 | 29915639 | Gastroenterology Res | A Case of Concomitant Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis Treated With CPAP Therapy. | 2018 | Details |
| A13567 | 29904722 | Clin Exp Hepatol | Underrated enemy - from nonalcoholic fatty liver disease to cancers of the gastrointestinal tract. | 2018 | Details |
| A13577 | 29898626 | Adipocyte | Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. | 2018 | Details |
| A13584 | 29895006 | Front Horm Res | The Metabolic Syndrome in Central Hypogonadotrophic Hypogonadism. | 2018 | Details |
| A13586 | 29893699 | Ann Hepatol | Impact of Diabetes Mellitus and Insulin on Nonalcoholic Fatty Liver Disease in the Morbidly Obese. | 2019 | Details |
| A13589 | 29892281 | Front Immunol | Distinct Housing Conditions Reveal a Major Impact of Adaptive Immunity on the Course of Obesity-Induced Type 2 Diabetes. | 2018 | Details |
| A13600 | 29885082 | Diabetes Obes Metab | No effect of resveratrol on VLDL-TG kinetics and insulin sensitivity in obese men with nonalcoholic fatty liver disease. | 2018 | Details |
| A13607 | 29881816 | Hepatol Commun | Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. | 2018 | Details |
| A13610 | 29880653 | Eur Respir J | Increased liver stiffness in patients with severe sleep apnoea and metabolic comorbidities. | 2018 | Details |
| A13618 | 29873257 | Syst Biol Reprod Med | Impact of prenatal arsenic exposure on chronic adult diseases. | 2018 | Details |
| A13619 | 29872017 | J Biosci | Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease. | 2018 | Details |
| A13627 | 29864915 | Biomed Pharmacother | Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. | 2018 | Details |
| A13628 | 29864682 | J Nutr Biochem | Non-alcoholic fatty liver disease severity and metabolic complications in obese children: impact of omega-3 fatty acids. | 2018 | Details |
| A13633 | 29861312 | J Diabetes Complications | Controlled attenuation parameter in NAFLD identifies risk of suboptimal glycaemic and metabolic control. | 2018 | Details |
| A13635 | 29860222 | Biomed Pharmacother | Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway. | 2018 | Details |
| A13637 | 29860108 | Atherosclerosis | Obesity and incidence of diabetes: Effect of absence of metabolic syndrome, insulin resistance, inflammation and fatty liver. | 2018 | Details |
| A13638 | 29860102 | J Nutr Biochem | Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet. | 2018 | Details |
| A13640 | 29859544 | Br J Nutr | Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function? | 2018 | Details |
| A13641 | 29859019 | Br J Pharmacol | A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway. | 2018 | Details |
| A13645 | 29858538 | Andrology | Benign prostatic hyperplasia and intraprostatic inflammation are associated with liver inflammation: it's time for prevention. | 2018 | Details |
| A13648 | 29857146 | Clin Gastroenterol Hepatol | Evaluations of Lifestyle, Dietary, and Pharmacologic Treatments for Pediatric Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2018 | Details |
| A13652 | 29855396 | J Dev Orig Health Dis | Early onset and progression of non-alcoholic fatty liver disease in young monosodium l-glutamate-induced obese mice. | 2018 | Details |
| A13653 | 29855033 | Histol Histopathol | Early effects of high-fat diet, extra-virgin olive oil and vitamin D in a sedentary rat model of non-alcoholic fatty liver disease. | 2018 | Details |
| A13654 | 29854716 | Can J Gastroenterol Hepatol | Predictive Value of Adiposity Level, Metabolic Syndrome, and Insulin Resistance for the Risk of Nonalcoholic Fatty Liver Disease Diagnosis in Obese Children. | 2018 | Details |
| A13655 | 29854715 | Can J Gastroenterol Hepatol | Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children. | 2018 | Details |
| A13659 | 29852170 | Biochem Biophys Res Commun | Suppression of NF-κB activation by PDLIM2 restrains hepatic lipogenesis and inflammation in high fat diet induced mice. | 2018 | Details |
| A13663 | 29849912 | Oxid Med Cell Longev | The Essential Element Manganese, Oxidative Stress, and Metabolic Diseases: Links and Interactions. | 2018 | Details |
| A13664 | 29849623 | Int J Endocrinol | Fatty Liver as a Potential Surrogate for Waist Circumference in the Diagnosis of Metabolic Syndrome: A Population-Based Study among Chinese Adults. | 2018 | Details |
| A13666 | 29848284 | Microrna | Serum miR-29a and miR-122 as Potential Biomarkers for Non-Alcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13672 | 29845719 | Intern Med J | Non-alcoholic fatty liver disease patients attending two metropolitan hospitals in Melbourne, Australia: high risk status and low prevalence. | 2018 | Details |
| A13677 | 29844588 | Nat Rev Gastroenterol Hepatol | Noninvasive biomarkers in NAFLD and NASH - current progress and future promise. | 2018 | Details |
| A13678 | 29844386 | Nat Commun | The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. | 2018 | Details |
| A13679 | 29844096 | Diabetes Care | Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars. | 2018 | Details |
| A13682 | 29843404 | Medicines (Basel) | Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13687 | 29805535 | Exp Ther Med | The therapeutic effects of bee venom on some metabolic and antioxidant parameters associated with HFD-induced non-alcoholic fatty liver in rats. | 2018 | Details |
| A13690 | 29804360 | Zhonghua Gan Zang Bing Za Zhi | [Effect of aerobic exercise and resistance exercise in improving non-alcoholic fatty liver disease: a randomized controlled trial]. | 2018 | Details |
| A13693 | 29803897 | Clin Chim Acta | Uric acid and cardiovascular disease. | 2018 | Details |
| A13695 | 29803210 | Neuro Endocrinol Lett | Shall we diagnose metabolic syndrome in adolescents? | 2018 | Details |
| A13698 | 29802679 | J Diabetes Investig | Soluble CD163 correlates with lipid metabolic adaptations in type 1 diabetes patients during ketoacidosis. | 2018 | Details |
| A13700 | 29802399 | Sci Rep | Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis. | 2018 | Details |
| A13701 | 29802129 | Diabetes | Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13702 | 29800811 | J Nutr Biochem | Synbiotics Bifidobacterium infantis and milk oligosaccharides are effective in reversing cancer-prone nonalcoholic steatohepatitis using western diet-fed FXR knockout mouse models. | 2018 | Details |
| A13710 | 29797516 | Eur J Clin Invest | Exercising the hepatobiliary-gut axis. The impact of physical activity performance. | 2018 | Details |
| A13714 | 29795358 | Acta Pharmacol Sin | Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice. | 2018 | Details |
| A13717 | 29793999 | Diabetes | The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. | 2018 | Details |
| A13723 | 29791184 | Child Obes | A Narrative Review of Medical and Genetic Risk Factors among Children Age 5 and Younger with Severe Obesity. | 2018 | Details |
| A13724 | 29790582 | Hepatology | Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents. | 2018 | Details |
| A13726 | 29788220 | Endocrinology | Obstructive Sleep Apnea Syndrome and Metabolic Diseases. | 2018 | Details |
| A13736 | 29785076 | World J Gastroenterol | Role of osteoprotegerin/receptor activator of nuclear factor kappa B/receptor activator of nuclear factor kappa B ligand axis in nonalcoholic fatty liver disease. | 2018 | Details |
| A13738 | 29783682 | Diseases | Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases. | 2018 | Details |
| A13756 | 29772784 | Nutrients | Capsaicin in Metabolic Syndrome. | 2018 | Details |
| A13758 | 29771124 | J Agric Food Chem | Genistein Ameliorates Non-alcoholic Fatty Liver Disease by Targeting the Thromboxane A2 Pathway. | 2018 | Details |
| A13759 | 29770757 | Br J Nutr | Soya protein β-conglycinin ameliorates fatty liver and obesity in diet-induced obese mice through the down-regulation of PPARγ. | 2018 | Details |
| A13766 | 29766802 | Curr Drug Targets | Endoplasmic Reticulum Stress Related Molecular Mechanisms in Nonalcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13767 | 29766801 | Curr Pharm Biotechnol | Naringenin and its Nano-formulations for Fatty Liver: Cellular Modes of Action and Clinical Perspective. | 2018 | Details |
| A13768 | 29766791 | Curr Pharm Des | Immunometabolic Changes in Hepatocytes Arising from Obesity and the Practice of Physical Exercise. | 2018 | Details |
| A13769 | 29765460 | Arch Med Sci | The role of intestinal microbiota in the pathogenesis of NAFLD: starting points for intervention. | 2016 | Details |
| A13770 | 29765172 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | Dietary sucrose regulates the expression of the Cd36 gene in hepatic tissue of rats with obesity and Non Alcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13772 | 29764990 | Sci Signal | IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. | 2018 | Details |
| A13785 | 29759071 | Lipids Health Dis | Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression. | 2018 | Details |
| A13792 | 29752404 | J Biol Chem | Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. | 2018 | Details |
| A13799 | 29749571 | J Gastroenterol | Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients. | 2018 | Details |
| A13805 | 29747118 | J Nutr Biochem | Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice. | 2018 | Details |
| A13819 | 29743560 | Cell Death Differ | Caspases in metabolic disease and their therapeutic potential. | 2018 | Details |
| A13827 | 29738703 | Chem Biol Interact | High fat diet induced obesity is mitigated in Cyp3a-null female mice. | 2018 | Details |
| A13833 | 29735794 | Ann Hepatol | The Presence and Severity of Nonalcoholic Steatohepatitis Is Associated with Specific Changes in Circulating Bile Acids. | 2018 | Details |
| A13839 | 29733805 | J Pediatr (Rio J) | IL-17A, MCP-1, CCR-2, and ABCA1 polymorphisms in children with non-alcoholic fatty liver disease. | 2018 | Details |
| A13843 | 29729191 | Hepatology | Caspase Recruitment Domain Protein 6 Protects Against Hepatic Steatosis and Insulin Resistance by Suppressing Apoptosis Signal-Regulating Kinase 1. | 2018 | Details |
| A13846 | 29729151 | Wiad Lek | Subclinical hypothyroidism in patients with non-alcoholic fatty liver disease at the background of carbohydrate metabolism disorders. | 2019 | Details |
| A13849 | 29728363 | Diabetes | Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes. | 2018 | Details |
| A13854 | 29725371 | Exp Ther Med | Analyses of risk factors for polycystic ovary syndrome complicated with non-alcoholic fatty liver disease. | 2018 | Details |
| A13856 | 29724029 | Int J Mol Sci | Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease: Beneficial Hepatic and Systemic Effects of Hormone Supplementation. | 2018 | Details |
| A13857 | 29723898 | Horm Metab Res | The Relationship Between Liver Enzymes and Insulin Resistance in Type 2 Diabetes Patients with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13867 | 29719598 | Oncotarget | Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver. | 2018 | Details |
| A13872 | 29717275 | Int J Obes (Lond) | Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers. | 2018 | Details |
| A13873 | 29717162 | Sci Rep | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. | 2018 | Details |
| A13875 | 29713608 | Pediatr Gastroenterol Hepatol Nutr | Investigation of Blood Betatrophin Levels in Obese Children with Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A13876 | 29713279 | Front Pharmacol | Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation. | 2018 | Details |
| A13878 | 29713129 | World J Gastroenterol | Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. | 2018 | Details |
| A13881 | 29712495 | Int J Biol Markers | Development of a novel diagnostic algorithm to predict NASH in HCV-positive patients. | 2018 | Details |