Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17819 | 27562557 | Toxicol Sci | Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis. | 2016 | Details |
| A17826 | 27553225 | FASEB J | Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses. | 2016 | Details |
| A17828 | 27549244 | Aliment Pharmacol Ther | Diagnostic performance of FibroTest, SteatoTest and ActiTest in patients with NAFLD using the SAF score as histological reference. | 2016 | Details |
| A17832 | 27548138 | Int J Mol Sci | Chemokine-Like Receptor 1 mRNA Weakly Correlates with Non-Alcoholic Steatohepatitis Score in Male but Not Female Individuals. | 2016 | Details |
| A17839 | 27545964 | Sci Rep | Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice. | 2016 | Details |
| A17857 | 27521506 | Clin Gastroenterol Hepatol | New Pharmacologic Agents That Target Inflammation and Fibrosis in Nonalcoholic Steatohepatitis-Related Kidney Disease. | 2016 | Details |
| A17864 | 27514759 | Liver Int | Weight loss induced by bariatric surgery restores adipose tissue PNPLA3 expression. | 2016 | Details |
| A17866 | 27514483 | Am J Physiol Gastrointest Liver Physiol | Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice. | 2016 | Details |
| A17879 | 27506731 | Metabolism | Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view. | 2016 | Details |
| A17880 | 27501771 | Br J Nutr | Differences in metabolic biomarkers in the blood and gene expression profiles of peripheral blood mononuclear cells among normal weight, mildly obese and moderately obese subjects. | 2016 | Details |
| A17889 | 27494683 | Int Immunopharmacol | High-fat diet plus carbon tetrachloride-induced liver fibrosis is alleviated by betaine treatment in rats. | 2016 | Details |
| A17900 | 27488610 | Eur J Nutr | The in vivo antineoplastic and therapeutic efficacy of troxerutin on rat preneoplastic liver: biochemical, histological and cellular aspects. | 2016 | Details |
| A17901 | 27487733 | Food Funct | Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice. | 2016 | Details |
| A17905 | 27485440 | Nutr J | Role of bioactive fatty acids in nonalcoholic fatty liver disease. | 2016 | Details |
| A17911 | 27483220 | Molecules | Efficacy of Acetylshikonin in Preventing Obesity and Hepatic Steatosis in db/db Mice. | 2016 | Details |
| A17917 | 27477770 | Immunol Lett | The complement component C5 promotes liver steatosis and inflammation in murine non-alcoholic liver disease model. | 2016 | Details |
| A17918 | 27477676 | Biochim Biophys Acta | SCD1 deficiency protects mice against ethanol-induced liver injury. | 2016 | Details |
| A17922 | 27475283 | Clin Nutr | Glucose homeostasis, insulin resistance and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: Beneficial effects of supplementation with microalgae Chlorella vulgaris: A double-blind placebo-controlled randomized clinical trial. | 2016 | Details |
| A17925 | 27473796 | Surg Clin North Am | The Effects of Metabolic Surgery on Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2016 | Details |
| A17927 | 27472963 | Biochim Biophys Acta Mol Cell Biol Lipids | Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis. | 2016 | Details |
| A17941 | 27464726 | Curr Pharm Des | Polycystic Ovary Syndrome as a Proinflammatory State: The Role of Adipokines. | 2016 | Details |
| A17943 | 27462372 | Diabetol Metab Syndr | Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes. | 2016 | Details |
| A17946 | 27458852 | Turk J Gastroenterol | Role of oxidative stress and insulin resistance in disease severity of non-alcoholic fatty liver disease. | 2016 | Details |
| A17951 | 27458060 | Menopause | Randomized clinical trial: benefits of aerobic physical activity for 24 weeks in postmenopausal women with nonalcoholic fatty liver disease. | 2016 | Details |
| A17953 | 27456850 | BMC Complement Altern Med | Anti-lipoapoptotic effects of Alisma orientalis extract on non-esterified fatty acid-induced HepG2 cells. | 2016 | Details |
| A17957 | 27454866 | PLoS One | Kupffer Cells Undergo Fundamental Changes during the Development of Experimental NASH and Are Critical in Initiating Liver Damage and Inflammation. | 2016 | Details |
| A17958 | 27454769 | PLoS One | Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17963 | 27447538 | Ann N Y Acad Sci | Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice. | 2016 | Details |
| A17964 | 27446914 | Front Cell Dev Biol | In vitro Modulation of the LPS-Induced Proinflammatory Profile of Hepatocytes and Macrophages- Approaches for Intervention in Obesity? | 2016 | Details |
| A17972 | 27443391 | BMC Med | Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease. | 2016 | Details |
| A17978 | 27439437 | J Proteome Res | Proteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD. | 2016 | Details |
| A17996 | 27429213 | J Dig Dis | Advances in noninvasive methods for diagnosing nonalcoholic fatty liver disease. | 2016 | Details |
| A18000 | 27424223 | J Nutr Biochem | Role of lipids in the metabolism and activation of immune cells. | 2015 | Details |
| A18004 | 27423696 | Am J Pathol | High-Fat Diet-Induced IL-17A Exacerbates Psoriasiform Dermatitis in a Mouse Model of Steatohepatitis. | 2016 | Details |
| A18009 | 27418954 | Oxid Med Cell Longev | Euterpe edulis Extract but Not Oil Enhances Antioxidant Defenses and Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Rats. | 2016 | Details |
| A18011 | 27417700 | J Sci Food Agric | Carrot juice ingestion attenuates high fructose-induced circulatory pro-inflammatory mediators in weanling Wistar rats. | 2016 | Details |
| A18023 | 27406999 | Sci Rep | CHIP(-/-)-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications. | 2016 | Details |
| A18027 | 27405060 | J Hepatol | Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors. | 2016 | Details |
| A18029 | 27404485 | FEBS Lett | p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer. | 2016 | Details |
| A18031 | 27402434 | Australas J Dermatol | The Australasian Psoriasis Collaboration view on methotrexate for psoriasis in the Australasian setting. | 2016 | Details |
| A18033 | 27401401 | Prostaglandins Other Lipid Mediat | Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis. | 2016 | Details |
| A18041 | 27391242 | PLoS One | An Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. | 2016 | Details |
| A18042 | 27389154 | Anatol J Cardiol | Non-alcoholic fatty liver disease-From the cardiologist perspective. | 2016 | Details |
| A18044 | 27388027 | Semin Arthritis Rheum | Psoriasis, psoriatic arthritis, and rheumatoid arthritis: Is all inflammation the same? | 2016 | Details |
| A18048 | 27384305 | Endocrinology | Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18061 | 27379445 | Inflamm Bowel Dis | Incidence and Predictors of Nonalcoholic Fatty Liver Disease by Serum Biomarkers in Patients with Inflammatory Bowel Disease. | 2016 | Details |
| A18070 | 27371158 | Exp Cell Res | Role of antigen presenting cell invariant chain in the development of hepatic steatosis in mouse model. | 2016 | Details |
| A18073 | 27367724 | Nutrients | Beneficial Effect of Synbiotic Supplementation on Hepatic Steatosis and Anthropometric Parameters, But Not on Gut Permeability in a Population with Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18075 | 27364348 | J Gastroenterol | Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model. | 2016 | Details |
| A18078 | 27363235 | Adolesc Med State Art Rev | Gastrointestinal Conditions in the Obese Patient. | 2016 | Details |
| A18081 | 27358638 | Afr Health Sci | Biochemical parameters response to weight loss in patients with non-alcoholic steatohepatitis. | 2016 | Details |
| A18093 | 27353492 | BMC Med | No effects of oral vitamin D supplementation on non-alcoholic fatty liver disease in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. | 2016 | Details |
| A18097 | 27352342 | Cell Biochem Biophys | Neutrophils Play a Crucial Role in the Early Stage of Nonalcoholic Steatohepatitis via Neutrophil Elastase in Mice. | 2015 | Details |
| A18100 | 27351828 | Int Immunopharmacol | Paeoniflorin alleviates non-alcoholic steatohepatitis in rats: Involvement with the ROCK/NF-κB pathway. | 2016 | Details |
| A18104 | 27349927 | Sci Rep | CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18109 | 27347998 | Nutrients | Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis. | 2016 | Details |
| A18110 | 27347680 | PLoS One | Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis. | 2016 | Details |
| A18118 | 27343380 | Eur J Pharmacol | (S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coagulation. | 2016 | Details |
| A18120 | 27342212 | Gastroenterology | Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol. | 2016 | Details |
| A18126 | 27339419 | Arch Toxicol | Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. | 2016 | Details |
| A18146 | 27321932 | Biochim Biophys Acta | Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice. | 2016 | Details |
| A18166 | 27310963 | Medicine (Baltimore) | The AST/ALT (De-Ritis) ratio: A novel marker for critical limb ischemia in peripheral arterial occlusive disease patients. | 2016 | Details |
| A18168 | 27310371 | PLoS One | Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway. | 2016 | Details |
| A18170 | 27309850 | PLoS One | Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. | 2016 | Details |
| A18181 | 27307131 | Phytother Res | Non-alcoholic Fatty Liver Disease: Beneficial Effects of Flavonoids. | 2016 | Details |
| A18194 | 27293995 | Am J Cancer Res | Lack of fibroblast growth factor 21 accelerates metabolic liver injury characterized by steatohepatities in mice. | 2016 | Details |
| A18208 | 27285989 | Oncotarget | Protein inhibitor of activated STAT 4 (PIAS4) regulates pro-inflammatory transcription in hepatocytes by repressing SIRT1. | 2016 | Details |
| A18219 | 27277679 | Cell Death Dis | DJ-1 deficiency attenuates expansion of liver progenitor cells through modulating the inflammatory and fibrogenic niches. | 2016 | Details |
| A18221 | 27277164 | Arch Pharm Res | Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease. | 2016 | Details |
| A18229 | 27271256 | J Mol Med (Berl) | A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease. | 2016 | Details |
| A18235 | 27266339 | J Med Food | Hepatoprotective Effects of Soybean Embryo by Enhancing Adiponectin-Mediated AMP-Activated Protein Kinase α Pathway in High-Fat and High-Cholesterol Diet-Induced Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18251 | 27262986 | Environ Toxicol Pharmacol | Impact of high-fat diet on liver genes expression profiles in mice model of nonalcoholic fatty liver disease. | 2016 | Details |
| A18257 | 27261776 | Mol Med | Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. | 2016 | Details |
| A18258 | 27261415 | J Hepatol | A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. | 2016 | Details |
| A18274 | 27248703 | J Gastroenterol Hepatol | "We are what our bacteria eat": The role of bacteria in personalizing nutrition therapy in gastrointestinal conditions. | 2017 | Details |
| A18278 | 27247565 | Gastroenterol Res Pract | The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background. | 2016 | Details |
| A18296 | 27233614 | Biochem Biophys Res Commun | Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. | 2016 | Details |
| A18299 | 27231887 | Molecules | Ethanolic Extract of Acanthopanax koreanum Nakai Alleviates Alcoholic Liver Damage Combined with a High-Fat Diet in C57BL/6J Mice. | 2016 | Details |
| A18303 | 27226903 | Sultan Qaboos Univ Med J | Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation. | 2016 | Details |
| A18311 | 27220460 | Int J Mol Med | Protective role of magnesium isoglycyrrhizinate in non-alcoholic fatty liver disease and the associated molecular mechanisms. | 2016 | Details |
| A18317 | 27216550 | J Cell Physiol | Association Between Aerobic Exercise and Rosiglitazone Avoided the NAFLD and Liver Inflammation Exacerbated in PPAR-α Knockout Mice. | 2016 | Details |
| A18318 | 27216040 | J Dig Dis | Role of intrahepatic B cells in non-alcoholic fatty liver disease by secreting pro-inflammatory cytokines and regulating intrahepatic T cells. | 2016 | Details |
| A18321 | 27213358 | Int J Mol Sci | The Natural Course of Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A18336 | 27197843 | Br J Nutr | Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats. | 2016 | Details |
| A18340 | 27196584 | Gut | Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation. | 2016 | Details |
| A18343 | 27194891 | J Clin Exp Hepatol | Changes in Liver Volume in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy. | 2015 | Details |
| A18348 | 27188904 | Nutr Res | Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor κB signaling. | 2016 | Details |
| A18366 | 27180087 | Toxicol Lett | Mainstream cigarette smoke accelerates the progression of nonalcoholic steatohepatitis by modulating Kupffer cell-mediated hepatocellular apoptosis in adolescent mice. | 2016 | Details |
| A18370 | 27178444 | Liver Int | Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. | 2016 | Details |
| A18375 | 27174364 | Br J Pharmacol | Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. | 2016 | Details |
| A18386 | 27170389 | Dig Dis | Non-Alcoholic Steatohepatitis: From Pathophysiology to Novel Therapies. | 2016 | Details |
| A18387 | 27169860 | BMC Res Notes | Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A18420 | 27146015 | Annu Rev Nutr | Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis. | 2016 | Details |
| A18431 | 27142736 | J Nutr Biochem | Fucoidan alleviates high-fat diet-induced dyslipidemia and atherosclerosis in ApoE(shl) mice deficient in apolipoprotein E expression. | 2016 | Details |
| A18440 | 27134062 | Nutr Metab Cardiovasc Dis | Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk. | 2016 | Details |
| A18454 | 27124606 | J Cardiovasc Pharmacol | Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2016 | Details |
| A18461 | 27116542 | Int J Cancer | Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation. | 2016 | Details |
| A18466 | 27110262 | Hepat Mon | Ginger Supplementation in Nonalcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. | 2016 | Details |
| A18467 | 27109475 | Biochem Biophys Res Commun | AMPKα1 overexpression alleviates the hepatocyte model of nonalcoholic fatty liver disease via inactivating p38MAPK pathway. | 2016 | Details |
| A18473 | 27105827 | Nutr J | Pathophysiological role of host microbiota in the development of obesity. | 2016 | Details |