Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A31179 | 31097447 | Biol Open | Dietary iron restriction leads to a reduction in hepatic fibrosis in a rat model of non-alcoholic steatohepatitis. | 2019 | Details |
| A31583 | 30248539 | Biomed Pharmacother | Effect of silibinin on CFLAR-JNK pathway in oleic acid-treated HepG2 cells. | 2018 | Details |
| A31591 | 30233790 | Biomed Rep | Oxidative stress induced by portal vein embolization in fatty liver: Experimental study of a nonalcoholic steatohepatitis model. | 2018 | Details |
| A31661 | 30084831 | J Lipid Res | Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice. | 2018 | Details |
| A31673 | 30057822 | Int J Hepatol | Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress. | 2018 | Details |
| A31681 | 30050648 | Oxid Med Cell Longev | Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure. | 2018 | Details |
| A31684 | 30046568 | Hepatobiliary Surg Nutr | A fermented mixed tea made with camellia (Camellia japonica) and third-crop green tea leaves prevents nonalcoholic steatohepatitis in Sprague-Dawley rats fed a high-fat and high-cholesterol diet. | 2018 | Details |
| A31939 | 29515450 | Front Pharmacol | Chymase Inhibitor as a Novel Therapeutic Agent for Non-alcoholic Steatohepatitis. | 2018 | Details |
| A32111 | 29180269 | Exp Mol Pathol | Dysregulation of antioxidant responses in patients diagnosed with concomitant Primary Sclerosing Cholangitis/Inflammatory Bowel Disease. | 2017 | Details |
| A32123 | 29154799 | Toxicology | Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. | 2017 | Details |
| A32152 | 29097836 | J Toxicol Pathol | The effect of β-caryophyllene on nonalcoholic steatohepatitis. | 2017 | Details |
| A32178 | 29046730 | Diabetol Metab Syndr | Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome. | 2017 | Details |
| A32319 | 28725667 | Data Brief | Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis. | 2017 | Details |
| A32331 | 28704693 | Ecotoxicol Environ Saf | Investigation of arsenic accumulation and biochemical response of in vitro developed Vetiveria zizanoides plants. | 2017 | Details |
| A32421 | 28487545 | Nat Rev Gastroenterol Hepatol | Mechanisms of hepatic stellate cell activation. | 2017 | Details |
| A32468 | 28365916 | Dig Dis Sci | Pigment Epithelium-Derived Factor (PEDF) Prevents Hepatic Fat Storage, Inflammation, and Fibrosis in Dietary Steatohepatitis of Mice. | 2017 | Details |
| A32548 | 28133511 | Toxicol Res | Evaluating the Influence of Side Stream Cigarette Smoke at an Early Stage of Non-Alcoholic Steatohepatitis Progression in Mice. | 2017 | Details |
| A32582 | 28066964 | Hepatol Res | Mechanisms of the prevention and inhibition of the progression and development of non-alcoholic steatohepatitis by genetic and pharmacological decoy receptor 3 supplementation. | 2017 | Details |
| A32601 | 28029729 | Hepatol Res | Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis. | 2017 | Details |
| A32820 | 27357826 | Mol Cell Biochem | MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters. | 2016 | Details |
| A32879 | 27182456 | J Clin Cell Immunol | Role of Serum Biomarkers in Early Detection of Non-Alcoholic Steatohepatitis and Fibrosis in West Virginian Children. | 2016 | Details |
| A32915 | 27095224 | Arch Biochem Biophys | The rise, the fall and the renaissance of vitamin E. | 2016 | Details |
| A32978 | 26937962 | PLoS One | Genetic Association and Gene-Gene Interaction Reveal Genetic Variations in ADH1B, GSTM1 and MnSOD Independently Confer Risk to Alcoholic Liver Diseases in India. | 2016 | Details |
| A33033 | 26828506 | Int J Environ Res Public Health | Biomarker-Based Approaches for Assessing Alcohol Use Disorders. | 2016 | Details |
| A33159 | 26579446 | Acta Pharm Sin B | Kallistatin, a new and reliable biomarker for the diagnosis of liver cirrhosis. | 2015 | Details |
| A33163 | 26576191 | Evid Based Complement Alternat Med | Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. | 2015 | Details |
| A33165 | 26566303 | J Clin Biochem Nutr | Sodium 4-phenylbutyrate prevents murine dietary steatohepatitis caused by trans-fatty acid plus fructose. | 2015 | Details |
| A33199 | 26483867 | World J Hepatol | Contribution of the toxic advanced glycation end-products-receptor axis in nonalcoholic steatohepatitis-related hepatocellular carcinoma. | 2015 | Details |
| A33316 | 26246839 | Evid Based Complement Alternat Med | Genistein Attenuates Nonalcoholic Steatohepatitis and Increases Hepatic PPARγ in a Rat Model. | 2015 | Details |
| A33370 | 26111628 | Mol Neurobiol | Hydrogen Sulfide Ameliorates Early Brain Injury Following Subarachnoid Hemorrhage in Rats. | 2015 | Details |
| A33489 | 25888871 | Lipids Health Dis | High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice. | 2015 | Details |
| A33490 | 25888330 | Gastroenterology | Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. | 2015 | Details |
| A33492 | 25885479 | J Agric Food Chem | Dietary Supplementation of Genistein Alleviates Liver Inflammation and Fibrosis Mediated by a Methionine-Choline-Deficient Diet in db/db Mice. | 2015 | Details |
| A33505 | 25848483 | World J Hepatol | Prevention of hepatocellular carcinoma: Focusing on antioxidant therapy. | 2015 | Details |
| A33583 | 25654228 | Int J Mol Sci | Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes. | 2015 | Details |
| A33639 | 25536170 | J Agric Food Chem | Purified anthocyanins from bilberry and black currant attenuate hepatic mitochondrial dysfunction and steatohepatitis in mice with methionine and choline deficiency. | 2015 | Details |
| A33643 | 25532502 | Dig Dis Sci | Curcumin targets multiple pathways to halt hepatic stellate cell activation: updated mechanisms in vitro and in vivo. | 2014 | Details |
| A33670 | 25461268 | Nitric Oxide | Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes. | 2014 | Details |
| A33676 | 25448926 | Gastroenterology | Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. | 2014 | Details |
| A33696 | 25385666 | Ir J Med Sci | Liver injury attenuation by curcumin in a rat NASH model: an Nrf2 activation-mediated effect? | 2014 | Details |
| A34018 | 24614199 | Lab Invest | Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. | 2014 | Details |
| A34044 | 24570954 | Hepatobiliary Surg Nutr | Eat more carrots? Dampening cell death in ethanol-induced liver fibrosis by β-carotene. | 2013 | Details |
| A34125 | 26858882 | Cell Med | Electron Therapy Attenuated Elevated Alanine Aminotransferase and Oxidative Stress Values in Type 2 Diabetes-Induced Nonalcoholic Steatohepatitis of Rats. | 2013 | Details |
| A34156 | 26202298 | Hepatol Int | Pharmacological agents for nonalcoholic steatohepatitis. | 2013 | Details |
| A34157 | 26202296 | Hepatol Int | Insulin resistance: mechanism and implications for carcinogenesis and hepatocellular carcinoma in NASH. | 2013 | Details |
| A34160 | 24273738 | Redox Biol | Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. | 2013 | Details |
| A34169 | 24242936 | Hepatology | Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker. | 2014 | Details |
| A34197 | 24156694 | J Toxicol Environ Health A | Oxidative stress, inflammatory biomarkers, and toxicity in mouse lung and liver after inhalation exposure to 100% biodiesel or petroleum diesel emissions. | 2013 | Details |
| A34238 | 23995653 | Biol Pharm Bull | Peroxisome proliferator-activated receptor γ (PPARγ)-independent specific cytotoxicity against immature adipocytes induced by PPARγ antagonist T0070907. | 2013 | Details |
| A34278 | 23877747 | Nutr Diabetes | Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury. | 2013 | Details |
| A34301 | 23822105 | Antioxid Redox Signal | Does hepatic oxidative stress enhance activation of nuclear factor-E2-related factor in patients with nonalcoholic steatohepatitis? | 2013 | Details |
| A34310 | 23793039 | Food Chem Toxicol | Nuclear erythroid 2-related factor 2: a novel potential therapeutic target for liver fibrosis. | 2013 | Details |
| A34313 | 23777387 | Hepatol Res | Therapeutic effects of the direct renin inhibitor, aliskiren, on non-alcoholic steatohepatitis in fatty liver Shionogi ob/ob male mice. | 2013 | Details |
| A34361 | 23640861 | Toxicol Sci | Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. | 2013 | Details |
| A34425 | 23481610 | Toxicol Appl Pharmacol | Persistent fibrosis in the liver of choline-deficient and iron-supplemented L-amino acid-defined diet-induced nonalcoholic steatohepatitis rat due to continuing oxidative stress after choline supplementation. | 2013 | Details |
| A34486 | 23339067 | Hepatology | Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents. | 2013 | Details |
| A34532 | 24695939 | Hepat Med | Treatment of nonalcoholic steatohepatitis with vitamins E and C: a pilot study. | 2013 | Details |
| A34549 | 23227320 | Hepat Res Treat | Antioxidant therapy in nonalcoholic steatohepatitis. | 2012 | Details |
| A34575 | 23170052 | J Clin Biochem Nutr | Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis. | 2012 | Details |
| A34583 | 23147115 | Int J Obes (Lond) | Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects. | 2012 | Details |
| A34680 | 22918204 | Acta Med Okayama | Water extract of Vitis coignetiae Pulliat leaves attenuates oxidative stress and inflammation in progressive NASH rats. | 2012 | Details |
| A34711 | 22804755 | J Pineal Res | Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin. | 2012 | Details |
| A34789 | 22592920 | Am J Respir Cell Mol Biol | Hydrogen sulfide attenuates particulate matter-induced human lung endothelial barrier disruption via combined reactive oxygen species scavenging and Akt activation. | 2012 | Details |
| A34790 | 22591204 | J Gastroenterol Hepatol | Dysregulated expression of fatty acid oxidation enzymes and iron-regulatory genes in livers of Nrf2-null mice. | 2012 | Details |
| A34884 | 22294490 | Phytother Res | Hepatoprotective effects of pycnogenol in a rat model of non-alcoholic steatohepatitis. | 2012 | Details |
| A34937 | 22182635 | Asian Pac J Trop Med | Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb--a review. | 2012 | Details |
| A34947 | 22176027 | Hepatol Res | Spontaneously hypertensive rats develop pronounced hepatic steatosis induced by choline-deficient diet: Evidence for hypertension as a potential enhancer in non-alcoholic steatohepatitis. | 2011 | Details |
| A34974 | 22100520 | Mutat Res | Decreased nucleotide excision repair in steatotic livers associates with myeloperoxidase-immunoreactivity. | 2011 | Details |
| A35002 | 22008477 | Life Sci | Cysteine aggravates palmitate-induced cell death in hepatocytes. | 2011 | Details |
| A35022 | 21933146 | Curr Pharm Des | Metabolic therapy: lessons from liver diseases. | 2011 | Details |
| A35052 | 21865331 | Am J Clin Nutr | Effect of lectin-like oxidized LDL receptor-1 polymorphism on liver disease, glucose homeostasis, and postprandial lipoprotein metabolism in nonalcoholic steatohepatitis. | 2011 | Details |
| A35059 | 21845516 | J Clin Immunol | Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A35124 | 21689613 | Clin Liver Dis | Insulin resistance and other metabolic risk factors in the pathogenesis of hepatocellular carcinoma. | 2011 | Details |
| A35196 | 21463986 | Eur J Med Res | Plasma levels of vitamin E and carotenoids are decreased in patients with Nonalcoholic Steatohepatitis (NASH). | 2011 | Details |
| A35205 | 21448070 | Eur J Gastroenterol Hepatol | Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. | 2011 | Details |
| A35224 | 21376711 | Chem Biol Interact | Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. | 2011 | Details |
| A35227 | 21373270 | J Clin Biochem Nutr | Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model. | 2010 | Details |
| A35259 | 21276150 | Hepatol Res | Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats. | 2011 | Details |
| A35286 | 21194384 | Antioxid Redox Signal | Transcriptional profile of genes involved in oxidative stress and antioxidant defense in a dietary murine model of steatohepatitis. | 2011 | Details |
| A35325 | 21081801 | J Physiol Pharmacol | The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis. | 2010 | Details |
| A35386 | 20849909 | Food Chem Toxicol | Clerodendron glandulosum.Coleb extract ameliorates high fat diet/fatty acid induced lipotoxicity in experimental models of non-alcoholic steatohepatitis. | 2010 | Details |
| A35388 | 20846698 | Metabolism | Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. | 2010 | Details |
| A35398 | 20832268 | Exp Toxicol Pathol | Sida rhomboidea.Roxb extract alleviates pathophysiological changes in experimental in vivo and in vitro models of high fat diet/fatty acid induced non-alcoholic steatohepatitis. | 2010 | Details |
| A35434 | 20683968 | Hepatology | Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. | 2010 | Details |
| A35453 | 20625232 | J Oleo Sci | Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35460 | 20607689 | Hepatology | High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. | 2010 | Details |
| A35462 | 20606728 | Int J Clin Exp Pathol | Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35480 | 20561512 | Chem Biol Interact | Hepatocyte or serum albumin protein carbonylation by oxidized fructose metabolites: Glyceraldehyde or glycolaldehyde as endogenous toxins? | 2010 | Details |
| A35496 | 20539006 | Am J Physiol Gastrointest Liver Physiol | Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. | 2010 | Details |
| A35509 | 20489159 | Am J Pathol | A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. | 2010 | Details |
| A35544 | 20395294 | J Biol Chem | Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. | 2010 | Details |
| A35566 | 20353017 | Zhongguo Zhong Yao Za Zhi | [Effect of total flavones of hawthorn leafon (TFHL) on expression of UCP2 in liver of NASH rats]. | 2009 | Details |
| A35584 | 20236361 | Hepatol Res | Identification of a novel biomarker for oxidative stress induced by hydrogen peroxide in primary human hepatocytes using the 2-nitrobenzenesulfenyl chloride isotope labeling method. | 2010 | Details |
| A35630 | 20068559 | Am J Gastroenterol | L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial. | 2010 | Details |
| A35693 | 19902025 | J Clin Biochem Nutr | A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH. | 2009 | Details |
| A35709 | 19856260 | Exp Clin Endocrinol Diabetes | Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? | 2009 | Details |
| A35710 | 19856102 | Dig Dis Sci | Highly purified eicosapentaenoic acid ethyl ester prevents development of steatosis and hepatic fibrosis in rats. | 2009 | Details |
| A35720 | 19841616 | Lab Invest | Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress. | 2009 | Details |
| A35732 | 19818291 | Eur J Intern Med | Oxidative stress and thyroid hormones in patients with liver diseases. | 2009 | Details |
| A35753 | 19764881 | Antioxid Redox Signal | Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice. | 2009 | Details |