Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17262 | 27881164 | BMC Endocr Disord | Administration of anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody for the treatment of osteoporosis was associated with amelioration of hepatitis in a female patient with growth hormone deficiency: a case report. | 2016 | Details |
| A17495 | 27720451 | Cell | Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. | 2016 | Details |
| A17534 | 27561910 | J Endocrinol Invest | Association between bone mineral density and nonalcoholic fatty liver disease in Korean adults. | 2016 | Details |
| A17626 | 27708340 | Sci Rep | Activation and increase of radio-sensitive CD11b+ recruited Kupffer cells/macrophages in diet-induced steatohepatitis in FGF5 deficient mice. | 2016 | Details |
| A17674 | 29744170 | Clin Exp Dent Res | Porphyromonas gingivalis induced periodontitis exacerbates progression of non-alcoholic steatohepatitis in rats. | 2016 | Details |
| A17678 | 27666673 | J Periodontol | Decrease of Pericytes is Associated With Liver Disease Caused by Ligature-Induced Periodontitis in Rats. | 2016 | Details |
| A17684 | 27660075 | Biol Trace Elem Res | HNF-4alpha Negatively Regulates Hepcidin Expression Through BMPR1A in HepG2 Cells. | 2016 | Details |
| A17771 | 27609031 | Exp Mol Med | MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis. | 2016 | Details |
| A17786 | 27594563 | Postepy Hig Med Dosw (Online) | New peptides players in metabolic disorders. | 2016 | Details |
| A17867 | 27514479 | Am J Physiol Gastrointest Liver Physiol | The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice. | 2016 | Details |
| A17880 | 27501771 | Br J Nutr | Differences in metabolic biomarkers in the blood and gene expression profiles of peripheral blood mononuclear cells among normal weight, mildly obese and moderately obese subjects. | 2016 | Details |
| A18075 | 27364348 | J Gastroenterol | Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model. | 2016 | Details |
| A18314 | 27218012 | Curr Hepatol Rep | Extrahepatic Manifestations of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18590 | 27044324 | Biol Open | Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism. | 2016 | Details |
| A18635 | 27021659 | Free Radic Res | Intermittent hypoxia upregulates hepatic heme oxygenase-1 and ferritin-1, thereby limiting hepatic pathogenesis in rats fed a high-fat diet. | 2016 | Details |
| A18757 | 26968296 | J Pak Med Assoc | Endocrine and metabolic effects of Glucagon like peptide 1 receptor agonists (GLP1RA). | 2016 | Details |
| A18964 | 26846206 | Sci Rep | Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. | 2016 | Details |
| A19060 | 26791408 | J Transl Med | The association of liver fat content and serum alanine aminotransferase with bone mineral density in middle-aged and elderly Chinese men and postmenopausal women. | 2016 | Details |
| A19103 | 26764184 | Gastroenterology | Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes. | 2016 | Details |
| A19143 | 26730275 | World J Hepatol | Management of non-alcoholic fatty liver disease in 2015. | 2015 | Details |
| A19196 | 26713058 | J Korean Med Sci | Vitamin D Status and Bone Mineral Density in Obese Children with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19309 | 26636404 | Eur J Gastroenterol Hepatol | Association of nonalcoholic fatty liver disease with bone mineral density and serum osteocalcin levels in Korean men. | 2016 | Details |
| A19463 | 26555669 | Mol Nutr Food Res | Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. | 2015 | Details |
| A19535 | 26503865 | Clin Calcium | [Bone complications in chronic liver disease(hepatic osteodystrophy)]. | 2015 | Details |
| A19661 | 26430807 | J Gastroenterol Hepatol | Gut-derived lymphocyte recruitment to liver and induce liver injury in non-alcoholic fatty liver disease mouse model. | 2016 | Details |
| A19695 | 26406121 | Hepatology | Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes. | 2015 | Details |
| A19834 | 26316717 | Drug Des Devel Ther | Nonalcoholic steatohepatitis: emerging targeted therapies to optimize treatment options. | 2015 | Details |
| A19840 | 26315331 | Diabet Med | Diabetic hepatosclerosis: another diabetes microvascular complication? | 2016 | Details |
| A19954 | 26242295 | Trials | The link between obesity and vitamin D in bariatric patients with omega-loop gastric bypass surgery - a vitamin D supplementation trial to compare the efficacy of postoperative cholecalciferol loading (LOAD): study protocol for a randomized controlled trial. | 2015 | Details |
| A20033 | 26198758 | Hepatol Int | Effect of metformin treatment on circulating osteoprotegerin in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20127 | 26138749 | Expert Rev Gastroenterol Hepatol | In search of the magic bullet: can liver inflammation and fibrosis be reversed with medications? | 2015 | Details |
| A20264 | 26056025 | J Bone Miner Metab | Circulating sclerostin and Dickkopf-1 levels in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20355 | 26018806 | Mol Med | Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20377 | 26003827 | J Endocrinol Invest | Nonalcoholic fatty liver disease and decreased bone mineral density: is there a link? | 2015 | Details |
| A20461 | 25947379 | J Biol Chem | 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma. | 2015 | Details |
| A20688 | 25798066 | Int J Biol Sci | Stem cell transplantation upregulates Sirt1 and antioxidant expression, ameliorating fatty liver in type 2 diabetic mice. | 2015 | Details |
| A20815 | 25715922 | Abdom Imaging | Quantification of liver, pancreas, kidney, and vertebral body MRI-PDFF in non-alcoholic fatty liver disease. | 2015 | Details |
| A20868 | 25677815 | Digestion | Association between serum osteocalcin levels and non-alcoholic fatty liver disease in women. | 2015 | Details |
| A20875 | 25671801 | Horm Metab Res | Does metformin treatment influence bone formation in patients with nonalcoholic fatty liver disease? | 2015 | Details |
| A20940 | 25627311 | Liver Int | Fetuin-A negatively correlates with liver and vascular fibrosis in nonalcoholic fatty liver disease subjects. | 2014 | Details |
| A21269 | 25445398 | J Hepatol | TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess. | 2014 | Details |
| A21287 | 25433106 | Nutr Hosp | Vitamin D levels and bone turnover markers are not related to non-alcoholic fatty liver disease in severely obese patients. | 2014 | Details |
| A21311 | 25413954 | J Inherit Metab Dis | The clinical spectrum of inherited diseases involved in the synthesis and remodeling of complex lipids. A tentative overview. | 2014 | Details |
| A21383 | 25356831 | PLoS One | Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans. | 2014 | Details |
| A21407 | 25345094 | Pediatr Endocrinol Rev | Lysosomal acid lipase deficiency: diagnosis and treatment of Wolman and Cholesteryl Ester Storage Diseases. | 2014 | Details |
| A21436 | 25318838 | J Gastroenterol Hepatol | Association between serum calcium and phosphorus concentrations with non-alcoholic fatty liver disease in Korean population. | 2015 | Details |
| A21490 | 25281859 | J Hepatol | Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice. | 2014 | Details |
| A21541 | 25242225 | Cell Metab | Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes. | 2014 | Details |
| A21838 | 25011936 | Gut | Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease. | 2014 | Details |
| A21919 | 24966597 | World J Gastroenterol | Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update. | 2014 | Details |
| A22149 | 24786317 | Exp Cell Res | Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model. | 2014 | Details |
| A22160 | 24781986 | PLoS One | Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice. | 2014 | Details |
| A22185 | 24760992 | Am J Physiol Endocrinol Metab | Mice lacking NOX2 are hyperphagic and store fat preferentially in the liver. | 2014 | Details |
| A22343 | 24650018 | Liver Int | Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis. | 2014 | Details |
| A22349 | 24647335 | J Pediatr Gastroenterol Nutr | Role of vitamin D in children with hepatosteatosis. | 2014 | Details |
| A22360 | 24638078 | PLoS One | Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity. | 2014 | Details |
| A22613 | 24412930 | Eur J Endocrinol | Vitamin D levels and liver histological alterations in children with nonalcoholic fatty liver disease. | 2014 | Details |
| A22868 | 24265809 | PLoS One | Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family. | 2013 | Details |
| A22911 | 24219909 | Cell Signal | Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways. | 2013 | Details |
| A22996 | 24129399 | Am J Physiol Endocrinol Metab | Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. | 2013 | Details |
| A23173 | 23983685 | Int J Endocrinol | Low bone mineral density in chinese adults with nonalcoholic Fatty liver disease. | 2013 | Details |
| A23178 | 23982157 | Am J Physiol Endocrinol Metab | Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice. | 2013 | Details |
| A23211 | 23958268 | Atherosclerosis | Independent associations of low 25 hydroxy vitamin D and high parathyroid hormonal levels with nonalcoholic fatty liver disease in Asian Indians residing in north India. | 2013 | Details |
| A23277 | 23905917 | J Allergy Clin Immunol | Innate sensors of pathogen and stress: linking inflammation to obesity. | 2013 | Details |
| A23340 | 23860122 | Am J Physiol Endocrinol Metab | MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet. | 2013 | Details |
| A23367 | 23840146 | World J Gastroenterol | Adipokines and C-reactive protein in relation to bone mineralization in pediatric nonalcoholic fatty liver disease. | 2013 | Details |
| A23395 | 23816817 | Trends Mol Med | Interactions among bone, liver, and adipose tissue predisposing to diabesity and fatty liver. | 2013 | Details |
| A23495 | 23727306 | J Hepatol | Dendritic cells in liver injury and fibrosis: shortcomings and promises. | 2013 | Details |
| A23510 | 25755488 | J Clin Exp Hepatol | Gut-liver axis: role of inflammasomes. | 2013 | Details |
| A23546 | 23692373 | Diabet Med | Late effects of childhood cancer treatment: severe hypertriglyceridaemia, central obesity, non alcoholic fatty liver disease and diabetes as complications of childhood total body irradiation. | 2013 | Details |
| A23771 | 23496113 | Pediatr Transplant | Pediatric post-transplant metabolic syndrome: new clouds on the horizon. | 2013 | Details |
| A23772 | 24843641 | J Diabetes Investig | Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: Incretin actions beyond the pancreas. | 2013 | Details |
| A24195 | 23131380 | Complement Ther Med | The effect of red yeast rice (Monascus purpureus) in dyslipidemia and other disorders. | 2012 | Details |
| A24217 | 23112047 | J Biol Chem | Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model. | 2012 | Details |
| A24283 | 23041327 | Gastroenterology | The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice. | 2012 | Details |
| A24337 | 22987396 | Hepatology | Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice. | 2013 | Details |
| A24482 | 22850810 | Wien Klin Wochenschr | The evaluation of bone mineral density in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24556 | 22751700 | Diabetes | Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. | 2012 | Details |
| A24579 | 22730920 | Aliment Pharmacol Ther | Review article: non-alcoholic fatty liver disease and osteoporosis--clinical and molecular crosstalk. | 2012 | Details |
| A24655 | 25755424 | J Clin Exp Hepatol | Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A24666 | 22634121 | J Hepatol | D-livering the message: the importance of vitamin D status in chronic liver disease. | 2012 | Details |
| A24746 | 22541706 | Clin Liver Dis | Nonalcoholic fatty liver disease. | 2012 | Details |
| A24805 | 22470565 | PLoS One | Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. | 2012 | Details |
| A24820 | 22466338 | J Clin Endocrinol Metab | Association between nonalcoholic fatty liver disease (NAFLD) and osteoporotic fracture in middle-aged and elderly Chinese. | 2012 | Details |
| A24880 | 22407492 | Endocrine | Association of nonalcoholic fatty liver disease with low bone mass in postmenopausal women. | 2012 | Details |
| A24883 | 22397032 | Adv Clin Chem | Fetuin-A and the cardiovascular system. | 2012 | Details |
| A24921 | 22359630 | PLoS One | Decreased circulating endothelial progenitor cell levels and function in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24954 | 22315014 | Endocrine | The role of pro/anti-inflammatory adipokines on bone metabolism in NAFLD obese adolescents: effects of long-term interdisciplinary therapy. | 2012 | Details |
| A24970 | 22295101 | PLoS One | LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. | 2012 | Details |
| A24976 | 22288305 | Eur Rev Med Pharmacol Sci | The psoriatic patient profile for infliximab. | 2011 | Details |
| A25175 | 22111971 | Aliment Pharmacol Ther | Non-alcoholic fatty liver disease is associated with low bone mineral density in obese children. | 2011 | Details |
| A25234 | 22067322 | Endocrinology | Prenatal dexamethasone exposure potentiates diet-induced hepatosteatosis and decreases plasma IGF-I in a sex-specific fashion. | 2011 | Details |
| A25338 | 21948338 | Dig Dis Sci | Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease. | 2011 | Details |
| A25379 | 21907177 | Am J Pathol | Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet. | 2011 | Details |
| A25415 | 25755327 | J Clin Exp Hepatol | Nuclear Factor High-mobility Group Box1 Mediating the Activation of Toll-like Receptor 4 Signaling in Hepatocytes in the Early Stage of Non-alcoholic Fatty Liver Disease in Mice. | 2011 | Details |
| A25456 | 21813474 | Gut | Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. | 2011 | Details |
| A25459 | 21809356 | Hepatology | Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. | 2011 | Details |
| A25686 | 21545576 | Br J Pharmacol | Resistin: functional roles and therapeutic considerations for cardiovascular disease. | 2012 | Details |
| A25703 | 21521307 | Clin Endocrinol (Oxf) | Correlation of insulin sensitivity with bone mineral status in obese adolescents with nonalcoholic fatty liver disease. | 2011 | Details |
| A25882 | 21356258 | J Hepatol | Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome. | 2011 | Details |