Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23245 | 23929677 | Hepatology | Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. | 2014 | Details |
| A23249 | 23928105 | Metabolism | Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. | 2013 | Details |
| A23252 | 23924495 | Hepatobiliary Pancreat Dis Int | Liver steatosis correlates with iron overload but not with HFE gene mutations in chronic hepatitis C. | 2013 | Details |
| A23267 | 23915028 | Free Radic Res | Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: cause or consequence? | 2013 | Details |
| A23273 | 23909258 | Vnitr Lek | [Effects of GLP-1 (glucagon-like peptide 1) on liver]. | 2013 | Details |
| A23277 | 23905917 | J Allergy Clin Immunol | Innate sensors of pathogen and stress: linking inflammation to obesity. | 2013 | Details |
| A23281 | 23900008 | Food Chem Toxicol | The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat diet-induced non-alcoholic fatty liver disease. | 2013 | Details |
| A23289 | 23896376 | Biochimie | Ectopic lipid accumulation: A potential cause for metabolic disturbances and a contributor to the alteration of kidney function. | 2013 | Details |
| A23303 | 23883694 | J Nutr Sci Vitaminol (Tokyo) | The effect of ethyl pyruvate supplementation on rat fatty liver induced by a high-fat diet. | 2013 | Details |
| A23311 | 23855304 | J Gastroenterol Hepatol | Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease. | 2013 | Details |
| A23322 | 23871755 | Free Radic Biol Med | MicroRNA modulation of lipid metabolism and oxidative stress in cardiometabolic diseases. | 2013 | Details |
| A23323 | 23870935 | Food Chem | Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats. | 2013 | Details |
| A23334 | 23862644 | Annu Rev Nutr | Omega-3 fatty acids, hepatic lipid metabolism, and nonalcoholic fatty liver disease. | 2013 | Details |
| A23338 | 23861108 | Dig Dis Sci | Betaine protects against high-fat-diet-induced liver injury by inhibition of high-mobility group box 1 and Toll-like receptor 4 expression in rats. | 2013 | Details |
| A23344 | 23855271 | Appl Physiol Nutr Metab | Branched-chain amino acids alleviate nonalcoholic steatohepatitis in rats. | 2013 | Details |
| A23373 | 23835912 | Clin Obstet Gynecol | Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the"first hit". | 2013 | Details |
| A23380 | 23832334 | Biosci Biotechnol Biochem | Hypolipidemic effects of starch and γ-oryzanol from wx/ae double-mutant rice on BALB/c.KOR-Apoe(shl) mice. | 2013 | Details |
| A23394 | 23819696 | Clin Exp Pharmacol Physiol | Supplementation of the maternal diet during pregnancy with chocolate and fructose interacts with the high-fat diet of the young to facilitate the onset of metabolic disorders in rat offspring. | 2013 | Details |
| A23396 | 23816341 | Diabetol Metab Syndr | Pleiotropic effects of rosuvastatin on the glucose metabolism and the subcutaneous and visceral adipose tissue behavior in C57Bl/6 mice. | 2013 | Details |
| A23397 | 23815500 | Antioxid Redox Signal | Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents? | 2013 | Details |
| A23400 | 23813132 | Ann Hepatol | Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. | 2013 | Details |
| A23426 | 23792031 | J Hepatol | The role of hepassocin in the development of non-alcoholic fatty liver disease. | 2013 | Details |
| A23430 | 23792151 | Biochimie | Zonation of glucose and fatty acid metabolism in the liver: mechanism and metabolic consequences. | 2013 | Details |
| A23431 | 23791610 | Eur J Pharmacol | Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα). | 2013 | Details |
| A23437 | 23784893 | Obesity (Silver Spring) | Predicting the effects of a high-energy diet on fatty liver and hippocampal-dependent memory in male rats. | 2013 | Details |
| A23439 | 23782652 | Mol Endocrinol | Disruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH. | 2013 | Details |
| A23456 | 23762326 | PLoS One | CCR2 and CD44 promote inflammatory cell recruitment during fatty liver formation in a lithogenic diet fed mouse model. | 2013 | Details |
| A23466 | 23755269 | PLoS One | Lepr(db/db) Mice with senescence marker protein-30 knockout (Lepr(db/db)Smp30(Y/-)) exhibit increases in small dense-LDL and severe fatty liver despite being fed a standard diet. | 2013 | Details |
| A23467 | 23754536 | Mol Med Rep | Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation. | 2013 | Details |
| A23472 | 23749645 | Cancer Res | Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma. | 2013 | Details |
| A23479 | 23744740 | Am J Physiol Gastrointest Liver Physiol | CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism. | 2013 | Details |
| A23491 | 23733885 | J Lipid Res | Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice. | 2013 | Details |
| A23493 | 23731053 | J Gastroenterol Hepatol | Epidemiological survey and risk factor analysis of fatty liver disease of adult residents, Beijing, China. | 2013 | Details |
| A23496 | 23727264 | Gastroenterology | Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease. | 2013 | Details |
| A23512 | 23720231 | Dis Model Mech | The expanding role of fish models in understanding non-alcoholic fatty liver disease. | 2013 | Details |
| A23519 | 23715726 | Am J Physiol Endocrinol Metab | Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet. | 2013 | Details |
| A23533 | 23703028 | Mol Cell Biochem | Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells. | 2013 | Details |
| A23539 | 23700488 | PLoS One | Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH. | 2013 | Details |
| A23568 | 23666886 | Obesity (Silver Spring) | Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease. | 2013 | Details |
| A23584 | 23656726 | Br J Nutr | Effects of long-term administration of saturated and n-3 fatty acid-rich diets on lipid utilisation and oxidative stress in rat liver and muscle tissues. | 2013 | Details |
| A23587 | 23654092 | Wei Sheng Yan Jiu | [Effects of Chinese wild rice on lipid metabolism and lipotoxicity in rats fed with high fat/cholesterol diet]. | 2013 | Details |
| A23590 | 23653231 | Mol Nutr Food Res | Effects of raftilose on serum biochemistry and liver morphology in rats fed with normal or high-fat diet. | 2013 | Details |
| A23596 | 23647015 | Br J Pharmacol | Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. | 2013 | Details |
| A23600 | 23641933 | BMC Infect Dis | Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. | 2013 | Details |
| A23603 | 23634883 | Lipids Health Dis | Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. | 2013 | Details |
| A23614 | 23626003 | J Clin Endocrinol Metab | Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage. | 2013 | Details |
| A23618 | 23623999 | J Hepatol | PTEN protein phosphatase activity regulates hepatitis C virus secretion through modulation of cholesterol metabolism. | 2013 | Details |
| A23623 | 23619824 | Cell Biol Int | Correlation analysis between gene expression profile of high-fat emulsion-induced non-alcoholic fatty liver and liver regeneration in rat. | 2013 | Details |
| A23627 | 23618531 | J Nutr Biochem | Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice. | 2013 | Details |
| A23629 | 23616151 | J Clin Endocrinol Metab | Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease. | 2013 | Details |
| A23630 | 23613622 | World J Gastroenterol | Dipeptidyl peptidase-4: a key player in chronic liver disease. | 2013 | Details |
| A23654 | 23594995 | Int J Mol Sci | Dual role of microRNAs in NAFLD. | 2013 | Details |
| A23656 | 23593497 | PLoS One | Neuroendocrine regulation and metabolism of glucose and lipids in primary chronic insomnia: a prospective case-control study. | 2013 | Details |
| A23665 | 23585904 | PLoS One | Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet. | 2013 | Details |
| A23682 | 23567085 | J Hepatol | Cannabinoid signaling and liver therapeutics. | 2013 | Details |
| A23690 | 23562079 | Cell Metab | Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. | 2013 | Details |
| A23696 | 23558065 | Hepatobiliary Pancreat Dis Int | Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges. | 2013 | Details |
| A23702 | 23554890 | PLoS One | Oral probiotic microcapsule formulation ameliorates non-alcoholic fatty liver disease in Bio F1B Golden Syrian hamsters. | 2013 | Details |
| A23717 | 23542537 | Biochem Pharmacol | The liver X receptor: a master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease. | 2013 | Details |
| A23720 | 23538201 | J Pharmacol Exp Ther | Ezetimibe increases hepatic iron levels in mice fed a high-fat diet. | 2013 | Details |
| A23725 | 23532271 | Braz J Med Biol Res | Effect and the probable mechanisms of silibinin in regulating insulin resistance in the liver of rats with non-alcoholic fatty liver. | 2013 | Details |
| A23733 | 23523139 | Diabetes Metab | MRI measurement of liver fat content predicts the metabolic syndrome. | 2013 | Details |
| A23747 | 23512881 | Obesity (Silver Spring) | A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population. | 2013 | Details |
| A23761 | 23505022 | Proteomics | Proteomic profile of carbonylated proteins in rat liver: exercise attenuated oxidative stress may be involved in fatty liver improvement. | 2013 | Details |
| A23763 | 23504926 | Hepatology | Both resistance training and aerobic training reduce hepatic fat content in type 2 diabetic subjects with nonalcoholic fatty liver disease (the RAED2 Randomized Trial). | 2013 | Details |
| A23781 | 23485520 | J Hepatol | The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease. | 2013 | Details |
| A23783 | 23483818 | World J Gastroenterol | From fatty liver to fibrosis: a tale of "second hit". | 2013 | Details |
| A23799 | 23472083 | PLoS One | Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism. | 2013 | Details |
| A23800 | 23467489 | Lab Anim | Gender and strain-specific differences in the development of steatosis in rats. | 2013 | Details |
| A23812 | 23453039 | Metabolism | Involvement of regucalcin in lipid metabolism and diabetes. | 2013 | Details |
| A23817 | 23451176 | PLoS One | Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis. | 2013 | Details |
| A23825 | 26064833 | J Lifestyle Med | Regulation of Cholesterol Metabolism in Liver: Link to NAFLD and Impact of n-3 PUFAs. | 2013 | Details |
| A23838 | 23435355 | Biochem Pharmacol | Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK-mTOR-SREBP signaling pathway. | 2013 | Details |
| A23839 | 23433827 | Med Hypotheses | Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation? | 2013 | Details |
| A23840 | 23433458 | Adv Pharmacol | Eicosanoids in metabolic syndrome. | 2013 | Details |
| A23848 | 23431284 | PPAR Res | Peroxisome proliferator-activated receptor genetic polymorphisms and nonalcoholic Fatty liver disease: any role in disease susceptibility? | 2013 | Details |
| A23880 | 23406154 | Lipids Health Dis | Effect of Mukitake mushroom (Panellus serotinus) on the pathogenesis of lipid abnormalities in obese, diabetic ob/ob mice. | 2013 | Details |
| A23887 | 23402081 | Acta Gastroenterol Belg | Pleiotropic functions of bile acids mediated by the farnesoid X receptor. | 2012 | Details |
| A23888 | 23401753 | J Obes | Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice. | 2013 | Details |
| A23894 | 23398201 | Biol Cell | PNPLA3/adiponutrin functions in lipid droplet formation. | 2013 | Details |
| A23895 | 23360884 | Br J Nutr | Gut microbiota and metabolic disorders: How prebiotic can work? | 2013 | Details |
| A23901 | 23395669 | Toxicol In Vitro | Sophocarpine alleviates hepatocyte steatosis through activating AMPK signaling pathway. | 2013 | Details |
| A23906 | 23394094 | Curr Pharm Des | Antioxidant therapy and drugs interfering with lipid metabolism: could they be effective in NAFLD patients? | 2013 | Details |
| A23920 | 23389749 | Food Funct | Hibiscus sabdariffa L. aqueous extract attenuates hepatic steatosis through down-regulation of PPAR-γ and SREBP-1c in diet-induced obese mice. | 2013 | Details |
| A23923 | 23387211 | Sichuan Da Xue Xue Bao Yi Xue Ban | [Impact of electro-acupuncture on lipid metalolism in rats with non-alcoholic fatty liver disease]. | 2012 | Details |
| A23936 | 23373292 | Vopr Kurortol Fizioter Lech Fiz Kult | [Balneotherapeutics of non-alcoholic fatty liver disease with the use of the Essentuki-type drinking mineral waters]. | 2013 | Details |
| A23954 | 23353867 | J Hepatol | Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis. | 2013 | Details |
| A23970 | 23339953 | J Hepatol | Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. | 2013 | Details |
| A23971 | 23337953 | Nat Rev Endocrinol | The role of hepatokines in metabolism. | 2013 | Details |
| A23978 | 23329754 | J Pediatr Endocrinol Metab | A decrease in fasting FGF19 levels is associated with the development of non-alcoholic fatty liver disease in obese adolescents. | 2012 | Details |
| A23982 | 23329013 | Dig Dis Sci | Fat mass and obesity-associated gene enhances oxidative stress and lipogenesis in nonalcoholic fatty liver disease. | 2013 | Details |
| A24007 | 23305008 | Klin Lab Diagn | [The unity of pathogenesis of insulin resistance syndrome and non-alcoholic fatty disease of liver. The metabolic disorder of fatty acids and triglycerides]. | 2012 | Details |
| A24017 | 23299992 | Hepatology | Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease. | 2013 | Details |
| A24019 | 23299577 | Hepatology | Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models. | 2013 | Details |
| A24055 | 23274901 | Diabetes | Sterol regulatory element-binding factor 2 (SREBF-2) predicts 7-year NAFLD incidence and severity of liver disease and lipoprotein and glucose dysmetabolism. | 2012 | Details |
| A24078 | 23258548 | Mol Pharmacol | 5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse model. | 2012 | Details |
| A24090 | 23236362 | PLoS One | Improved glycaemia correlates with liver fat reduction in obese, type 2 diabetes, patients given glucagon-like peptide-1 (GLP-1) receptor agonists. | 2012 | Details |
| A24094 | 23234151 | Zhongguo Zhong Yao Za Zhi | [Clinical study on prevention efficacy of Jianpi Huatan Fang in treating non-alcoholic fatty liver disease in children]. | 2012 | Details |
| A24105 | 23226761 | Exp Ther Med | Tesaglitazar ameliorates non-alcoholic fatty liver disease and atherosclerosis development in diabetic low-density lipoprotein receptor-deficient mice. | 2012 | Details |
| A24112 | 23220074 | Nutr Metab Cardiovasc Dis | Docosahexaenoic acid for the treatment of fatty liver: randomised controlled trial in children. | 2012 | Details |