Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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CLA3884 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A45023 | 26409177 | Gastroenterology | Liver histology and clinical trials for nonalcoholic steatohepatitis-perspectives from 2 pathologists. | 2015 | Details |
| A45220 | 25624707 | World J Gastroenterol | Liver enzymes, metabolomics and genome-wide association studies: from systems biology to the personalized medicine. | 2015 | Details |
| A45232 | 25588104 | J Interferon Cytokine Res | Fatty Acids Induce a Pro-Inflammatory Gene Expression Profile in Huh-7 Cells That Attenuates the Anti-HCV Action of Interferon. | 2015 | Details |
| A45250 | 25548259 | J Lipid Res | ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content. | 2014 | Details |
| A45261 | 25489472 | Ther Adv Endocrinol Metab | Vitamin D insufficiency and insulin resistance in obese adolescents. | 2014 | Details |
| A45309 | 25240528 | Acta Diabetol | Glypican-4 is increased in human subjects with impaired glucose tolerance and decreased in patients with newly diagnosed type 2 diabetes. | 2014 | Details |
| A45311 | 25239591 | Gastroenterology | Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. | 2014 | Details |
| A45342 | 25111132 | JAMA Pediatr | Origin of cardiovascular risk in overweight preschool children: a cohort study of cardiometabolic risk factors at the onset of obesity. | 2014 | Details |
| A45388 | 24859739 | J Lipid Res | Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells. | 2014 | Details |
| A45408 | 24763554 | Am J Physiol Gastrointest Liver Physiol | Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells. | 2014 | Details |
| A45411 | 24748831 | J Ginseng Res | AMP-activated protein kinase: An emerging target for ginseng. | 2013 | Details |
| A45430 | 24659251 | Curr Gastroenterol Rep | Management of hyponatremia in clinical hepatology practice. | 2014 | Details |
| A45439 | 24582101 | Endocrinol Metab Clin North Am | Relationships between diabetes and cognitive impairment. | 2013 | Details |
| A45488 | 24346721 | Rev Saude Publica | [Medical assessments and measurements in ELSA-Brasil]. | 2013 | Details |
| A45495 | 24314883 | Surgery | Chemotherapy-associated liver injury and its influence on outcome after resection of colorectal liver metastases. | 2013 | Details |
| A45500 | 24284330 | Tohoku J Exp Med | The association between dietary lifestyles and hepatocellular injury in Japanese workers. | 2013 | Details |
| A45521 | 24170694 | Diabetes | ITCH deficiency protects from diet-induced obesity. | 2013 | Details |
| A45545 | 23999826 | Endocr Connect | Increased FGF21 plasma levels in humans with sepsis and SIRS. | 2013 | Details |
| A45552 | 23959055 | Ann Surg Oncol | Evaluation of the usefulness of the indocyanine green clearance test for chemotherapy-associated liver injury in patients with colorectal cancer liver metastasis. | 2014 | Details |
| A45557 | 23914059 | J Toxicol Pathol | Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice. | 2013 | Details |
| A45578 | 26201923 | Hepatol Int | Roles of alcohol drinking pattern in fatty liver in Japanese women. | 2013 | Details |
| A45599 | 23715754 | Diabetes Care | Dual peroxisome proliferator-activated receptor α/δ agonist GFT505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. | 2013 | Details |
| A45602 | 23710178 | Int J Endocrinol | Major Histocompatibility Class II Pathway Is Not Required for the Development of Nonalcoholic Fatty Liver Disease in Mice. | 2013 | Details |
| A45640 | 23495130 | Liver Transpl | High prevalence of vitamin A deficiency and vitamin D deficiency in patients evaluated for liver transplantation. | 2013 | Details |
| A45677 | 23316217 | PPAR Res | PPAR Could Contribute to the Pathogenesis of Hepatocellular Carcinoma. | 2012 | Details |
| A45707 | 23175050 | Hepatology | Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats. | 2013 | Details |
| A45709 | 23161873 | Endocrinology | The role of the carbohydrate response element-binding protein in male fructose-fed rats. | 2012 | Details |
| A45713 | 23144998 | PLoS One | Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. | 2012 | Details |
| A45761 | 22891562 | Pol Merkur Lekarski | [Evaluation of alpha-fetoprotein concentration in patients with chronic liver diseases]. | 2012 | Details |
| A45794 | 22701308 | J Biomed Biotechnol | Think small: zebrafish as a model system of human pathology. | 2012 | Details |
| A45807 | 22646861 | Expert Opin Drug Discov | Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk. | 2011 | Details |
| A45836 | 23798298 | Compr Physiol | Lack of exercise is a major cause of chronic diseases. | 2012 | Details |
| A45845 | 22425588 | Gastroenterology | Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. | 2012 | Details |
| A45897 | 22154323 | Metabolism | Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice. | 2011 | Details |
| A45928 | 22018903 | Hum Pathol | The steatohepatitic variant of hepatocellular carcinoma and its association with underlying steatohepatitis. | 2011 | Details |
| A45971 | 21772667 | Mediators Inflamm | Foxp3 expression in liver correlates with the degree but not the cause of inflammation. | 2011 | Details |
| A46007 | 21618266 | Hepatology | Nonalcoholic fatty liver disease activity score and Brunt's pathologic criteria for the diagnosis of nonalcoholic steatohepatitis: what do they mean and do they agree? | 2011 | Details |
| A46009 | 21601719 | Gen Hosp Psychiatry | Prevalence of liver disease in veterans with bipolar disorder or schizophrenia. | 2011 | Details |
| A46012 | 21557278 | Hepatology | Diagnosing steatohepatitis and predicting liver-related mortality in patients with NAFLD: two distinct concepts. | 2011 | Details |
| A46017 | 21536711 | Endocr Rev | Genetic syndromes of severe insulin resistance. | 2011 | Details |
| A46025 | 21505361 | J Pediatr Gastroenterol Nutr | Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease. | 2011 | Details |
| A46030 | 21488072 | Hepatology | Misuse of scoring systems. | 2011 | Details |
| A46032 | 21476910 | Expert Rev Gastroenterol Hepatol | Relevance of TNF-α gene polymorphisms in nonalcoholic fatty liver disease. | 2011 | Details |
| A46045 | 21435084 | Helicobacter | The association between Helicobacter pylori infection and insulin resistance: a systematic review. | 2011 | Details |
| A46049 | 21423007 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2011 | Details |
| A46085 | 21194387 | Antioxid Redox Signal | Adipokines and redox signaling: impact on fatty liver disease. | 2011 | Details |
| A46129 | 20863537 | Metabolism | Serum uric acid levels predict incident nonalcoholic fatty liver disease in healthy Korean men. | 2010 | Details |
| A46139 | 20807839 | Am J Physiol Endocrinol Metab | A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. | 2010 | Details |
| A46141 | 20799351 | Hepatology | Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. | 2010 | Details |
| A46191 | 20454765 | ScientificWorldJournal | Resolution of adipose tissue inflammation. | 2010 | Details |
| A46192 | 20452916 | J Am Pharm Assoc (2003) | Clarifying metformin's role and risks in liver dysfunction. | 2010 | Details |
| A46209 | 20371660 | J Clin Endocrinol Metab | Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. | 2010 | Details |
| A46211 | 20360293 | Mayo Clin Proc | Statins in the treatment of dyslipidemia in the presence of elevated liver aminotransferase levels: a therapeutic dilemma. | 2010 | Details |
| A46218 | 20222092 | Hepatology | Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease. | 2010 | Details |
| A46233 | 20151095 | J Pediatr (Rio J) | Hepatic steatosis in a school population of overweight and obese adolescents. | 2010 | Details |
| A46238 | 20116466 | Gastroenterology | The role of iron in nonalcoholic fatty liver disease: the story continues. | 2010 | Details |
| A46253 | 19967814 | Eksp Klin Gastroenterol | [The evolution of ideas about nonalcohol fatty liver disease]. | 2009 | Details |
| A46259 | 19949375 | Lab Invest | Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet. | 2009 | Details |
| A46269 | 19913850 | Metabolism | The possible role of liver steatosis in defining metabolic syndrome in prepubertal children. | 2009 | Details |
| A46272 | 19877024 | Liver Transpl | Obesity, hyperlipidemia, and metabolic syndrome. | 2009 | Details |
| A46278 | 19822488 | Hepatobiliary Pancreat Dis Int | Diabetes mellitus: a "true" independent risk factor for hepatocellular carcinoma? | 2009 | Details |
| A46300 | 19700042 | Clin Chest Med | The obesity epidemic. | 2009 | Details |
| A46302 | 19642734 | Arch Pathol Lab Med | Recent developments in liver pathology. | 2009 | Details |
| A46304 | 19637289 | Hepatology | Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. | 2009 | Details |
| A46310 | 19585655 | Hepatology | Adipokines in liver diseases. | 2009 | Details |
| A46344 | 19404203 | Eur J Gastroenterol Hepatol | Hepatocellular adenoma in advanced-stage fatty liver disease. | 2009 | Details |
| A46345 | 19403641 | Am J Clin Nutr | Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. | 2009 | Details |
| A46381 | 19161394 | Pediatr Diabetes | Treatment of non-alcoholic fatty liver disease in children: swim at your own risk. | 2009 | Details |
| A46419 | 18821593 | Hepatology | Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: a nationwide analysis. | 2008 | Details |
| A46437 | 18666246 | Hepatology | Statins in liver disease: a molehill, an iceberg, or neither? | 2008 | Details |
| A46444 | 18619079 | Am Fam Physician | Gastrointestinal complications of diabetes. | 2008 | Details |
| A46446 | 18607271 | J Pediatr Gastroenterol Nutr | Intima-media thickness of carotid artery and susceptibility to atherosclerosis in obese children with nonalcoholic fatty liver disease. | 2008 | Details |
| A46449 | 18563842 | Hepatology | Accuracy and reproducibility of transient elastography for the diagnosis of fibrosis in pediatric nonalcoholic steatohepatitis. | 2008 | Details |
| A46454 | 18523032 | J Endocrinol | Antagonism of central melanin-concentrating hormone 1 receptor alleviates steatohepatitis in mice. | 2008 | Details |
| A46459 | 18460980 | Am J Surg Pathol | Histologic abnormalities are common in protocol liver allograft biopsies from patients with normal liver function tests. | 2008 | Details |
| A46463 | 18445722 | Diabetes Care | Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with adult treatment panel III criteria in nonobese nondiabetic subjects: response to Musso et al. | 2008 | Details |
| A46464 | 18438784 | Hepatology | HFE mutations in nonalcoholic fatty liver disease. | 2008 | Details |
| A46486 | 18355813 | Gastroenterology | Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. | 2008 | Details |
| A46489 | 18344805 | Medicine (Baltimore) | Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. | 2008 | Details |
| A46497 | 18253138 | Nat Clin Pract Gastroenterol Hepatol | Technology Insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography. | 2008 | Details |
| A46510 | 30743783 | Expert Rev Endocrinol Metab | Inflammatory biomarkers associated with obesity and insulin resistance: a focus on lipocalin-2 and adipocyte fatty acid-binding protein. | 2008 | Details |
| A46526 | 17959863 | Diabetes Care | Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations. | 2007 | Details |
| A46543 | 17729388 | World J Gastroenterol | Should nonalcoholic fatty liver disease be regarded as a hepatic illness only? | 2007 | Details |
| A46554 | 17666460 | Diabetes Care | Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-aged Japanese men. | 2007 | Details |
| A46555 | 17661402 | Hepatology | A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. | 2007 | Details |
| A46591 | 17408630 | Gastroenterology | The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. | 2007 | Details |
| A46614 | 17278239 | World J Gastroenterol | Indian patients with nonalcoholic fatty liver disease presenting with raised transaminases are different at presentation. | 2007 | Details |
| A46627 | 17160239 | Arq Gastroenterol | Prevalence of the hemochromatosis gene mutation in patients with nonalcoholic steatohepatitis and correlation with degree of liver fibrosis. | 2007 | Details |
| A46632 | 17099068 | FASEB J | Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo. | 2006 | Details |
| A46637 | 17036578 | Mayo Clin Proc | Long-term outcome of bariatric surgery: an interim analysis. | 2006 | Details |
| A46647 | 16912555 | Curr Opin Clin Nutr Metab Care | Assessment of metabolic profile in a clinical setting. | 2006 | Details |
| A46657 | 16825675 | Am J Clin Nutr | Nonalcoholic fatty liver, nonalcoholic steatohepatitis, ectopic fat, and the glycemic index. | 2006 | Details |
| A46683 | 16555318 | Liver Transpl | Nonalcoholic fatty liver disease and liver transplantation. | 2006 | Details |
| A46684 | 16550033 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2006 | Details |
| A46708 | 16311087 | Metabolism | Hyperinsulinemia predicts hepatic fat content in healthy individuals with normal transaminase concentrations. | 2005 | Details |
| A46717 | 16259894 | Obes Surg | Non-alcoholic fatty liver disease: scoring systems need standardization, but are we ready? | 2005 | Details |
| A46722 | 16220049 | Curr Opin Gastroenterol | Role of inflammation in nonalcoholic steatohepatitis. | 2005 | Details |
| A46737 | 16053912 | Eur J Med Genet | Case report of a patient with non-alcoholic fatty liver disease, moderate iron overload who is homozygous for the S65C mutation in the HFE1 gene. | 2005 | Details |
| A46744 | 15989823 | Gastroenterol Hepatol | [Non-alcoholic fatty liver disease, serum iron indexes and iron concentration in the liver]. | 2005 | Details |
| A46774 | 15703564 | Curr Opin Gastroenterol | Hepatocellular carcinoma. | 2003 | Details |