Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11271 | 30965069 | J Hepatol | Prospective evaluation of a primary care referral pathway for patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A11274 | 30964207 | Hepatology | MicroRNA-223 Ameliorates Nonalcoholic Steatohepatitis and Cancer by Targeting Multiple Inflammatory and Oncogenic Genes in Hepatocytes. | 2019 | Details |
| A11276 | 30962743 | Yonago Acta Med | Gene Expression Analysis of the Activating Factor 3/Nuclear Protein 1 Axis in a Non-alcoholic Steatohepatitis Mouse Model. | 2019 | Details |
| A11279 | 30961499 | Curr Vasc Pharmacol | Non-Alcoholic Fatty Liver Disease Treatment in Patients with Type 2 Diabetes Mellitus; New Kids on the Block. | 2020 | Details |
| A11280 | 30959577 | Hepatology | Fructose Promotes Leaky Gut, Endotoxemia, and Liver Fibrosis Through Ethanol-Inducible Cytochrome P450-2E1-Mediated Oxidative and Nitrative Stress. | 2019 | Details |
| A11284 | 30958562 | Histol Histopathol | Modulatory effect of inulin with soya isoflavones on plasma lipid profile and liver SCD-18 index in rats with induced type-2 diabetes mellitus. | 2019 | Details |
| A11287 | 30954713 | Clin Gastroenterol Hepatol | Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With Fatty Liver Disease. | 2019 | Details |
| A11293 | 30951700 | Exp Mol Pathol | The different expression of tumor suppressors, RASSF1A, RUNX3, and GSTP1, in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A11294 | 30951517 | Am J Gastroenterol | An AGTR1 Variant Worsens Nonalcoholic Fatty Liver Disease and the Metabolic Syndrome. | 2019 | Details |
| A11309 | 30945293 | J Pathol | Bone marrow-derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells. | 2019 | Details |
| A11310 | 30945129 | Curr Obes Rep | Nonalcoholic Fatty Liver Disease and Obesity Treatment. | 2019 | Details |
| A11312 | 30943987 | J Transl Med | Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: consequences of high fat-fructose-cholesterol diet and diabetes. | 2019 | Details |
| A11313 | 30943218 | PLoS One | Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice. | 2019 | Details |
| A11316 | 30942432 | Int J Mol Med | Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non‑alcoholic fatty liver disease mouse model. | 2019 | Details |
| A11317 | 30941061 | Front Physiol | Regulatory Non-coding RNAs Network in Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A11318 | 30940491 | Nutr Metab Cardiovasc Dis | Non alcoholic fatty liver disease and risk of incident diabetes in subjects who are not obese. | 2019 | Details |
| A11321 | 30939745 | Int J Mol Sci | 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. | 2019 | Details |
| A11324 | 30937868 | Adv Exp Med Biol | Pericytes in the Liver. | 2019 | Details |
| A11335 | 30932742 | OMICS | Novel Serum Biomarkers for Noninvasive Diagnosis and Screening of Nonalcoholic Fatty Liver Disease-Related Hepatic Fibrosis. | 2019 | Details |
| A11337 | 30931596 | Orv Hetil | [Alcoholic liver disease: the roles of genetic-epigenetic factors and the effect of abstinence]. | 2019 | Details |
| A11347 | 30928418 | Dig Liver Dis | Different predictors of steatosis and fibrosis severity among lean, overweight and obese patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A11355 | 30924946 | Hepatology | Sex Differences in Nonalcoholic Fatty Liver Disease: State of the Art and Identification of Research Gaps. | 2019 | Details |
| A11358 | 30923657 | PeerJ | Identification of key genes, pathways and potential therapeutic agents for liver fibrosis using an integrated bioinformatics analysis. | 2019 | Details |
| A11375 | 30919331 | Adv Exp Med Biol | Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions. | 2019 | Details |
| A11379 | 30918425 | World J Gastroenterol | Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice. | 2019 | Details |
| A11380 | 30918325 | Lab Invest | Human relaxin-2 attenuates hepatic steatosis and fibrosis in mice with non-alcoholic fatty liver disease. | 2019 | Details |
| A11383 | 30917662 | Rev Esp Enferm Dig | Characterizing specific subgroups in patients with NAFLD: overweight vs obese phenotype. | 2019 | Details |
| A11385 | 30917489 | Int J Mol Sci | MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice. | 2019 | Details |
| A11393 | 30915402 | Clin Exp Hepatol | Update on pathogenesis, diagnostics and therapy of nonalcoholic fatty liver disease in children. | 2019 | Details |
| A11398 | 30912854 | Hepatology | Relationship Between PNPLA3 rs738409 Polymorphism and Decreased Kidney Function in Children With NAFLD. | 2019 | Details |
| A11399 | 30912337 | Endocrinol Metab (Seoul) | Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases. | 2019 | Details |
| A11400 | 30912307 | Physiol Rep | The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats. | 2019 | Details |
| A11401 | 30912255 | Liver Int | Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue. | 2019 | Details |
| A11402 | 30912099 | Semin Liver Dis | Genetics of Nonalcoholic Fatty Liver Disease: From Pathogenesis to Therapeutics. | 2019 | Details |
| A11405 | 30908678 | Hepatology | A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease. | 2019 | Details |
| A11406 | 30908654 | J Cell Physiol | Inhibition of lncRNA HULC improves hepatic fibrosis and hepatocyte apoptosis by inhibiting the MAPK signaling pathway in rats with nonalcoholic fatty liver disease. | 2019 | Details |
| A11407 | 30907181 | Scand J Gastroenterol | Non-invasive fibrosis scoring systems can predict future metabolic complications and overall mortality in non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A11421 | 30901317 | Rom J Intern Med | Non-alcoholic fatty pancreas disease - practices for clinicians. | 2019 | Details |
| A11422 | 30901032 | J Clin Endocrinol Metab | Dysregulation of the Splicing Machinery Is Associated to the Development of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11427 | 30899593 | J Adv Res | Repin1 deficiency in liver tissue alleviates NAFLD progression in mice. | 2018 | Details |
| A11430 | 30897538 | Biomed Pharmacother | Biological mechanisms and related natural modulators of liver X receptor in nonalcoholic fatty liver disease. | 2019 | Details |
| A11434 | 30896957 | Rev Esp Enferm Dig | Bariatric and metabolic endoscopy in the handling of fatty liver disease. A new emerging approach? | 2019 | Details |
| A11440 | 30894137 | BMC Gastroenterol | The role of Small Intestinal Bacterial Overgrowth (SIBO) in Non-alcoholic Fatty Liver Disease (NAFLD) patients evaluated using Controlled Attenuation Parameter (CAP) Transient Elastography (TE): a tertiary referral center experience. | 2019 | Details |
| A11442 | 30893090 | Curr Opin Clin Nutr Metab Care | Sarcopenic obesity in fatty liver. | 2019 | Details |
| A11446 | 30891617 | J Mol Med (Berl) | Innate immune regulatory networks in hepatic lipid metabolism. | 2019 | Details |
| A11451 | 30889343 | Rev Med Inst Mex Seguro Soc | Nonalcoholic hepatic steatosis: a silent disease | 2019 | Details |
| A11453 | 30888972 | Eur J Gastroenterol Hepatol | Neutrophil-to-lymphocyte ratio is independently associated with inflammatory activity and fibrosis grade in nonalcoholic fatty liver disease. | 2019 | Details |
| A11454 | 30888971 | Eur J Gastroenterol Hepatol | Associations between sarcopenia and nonalcoholic fatty liver disease and advanced fibrosis in the USA. | 2019 | Details |
| A11461 | 30887659 | Int J Exp Pathol | Vitronectin deficiency attenuates hepatic fibrosis in a non-alcoholic steatohepatitis-induced mouse model. | 2019 | Details |
| A11463 | 30885145 | BMC Gastroenterol | The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose. | 2019 | Details |
| A11468 | 30882933 | Aliment Pharmacol Ther | Collagen proportionate area is an independent predictor of long-term outcome in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A11470 | 30882489 | AIDS | Monocyte-macrophage activation is associated with nonalcoholic fatty liver disease and liver fibrosis in HIV monoinfection independently of the gut microbiome and bacterial translocation. | 2019 | Details |
| A11475 | 30881075 | Diabetes Metab Syndr Obes | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease. | 2019 | Details |
| A11476 | 30879942 | J Clin Lipidol | Extremely low levels of low-density lipoprotein potentially suggestive of familial hypobetalipoproteinemia: A separate phenotype of NAFLD? | 2019 | Details |
| A11481 | 30877708 | Diabetes Metab J | Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus. | 2019 | Details |
| A11485 | 30876959 | Clin Gastroenterol Hepatol | Optimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients With Advanced Fibrosis. | 2019 | Details |
| A11486 | 30876789 | J Formos Med Assoc | The correlation between fatty liver disease and chronic kidney disease. | 2019 | Details |
| A11487 | 30875804 | Int J Mol Sci | TM6SF2 and MBOAT7 Gene Variants in Liver Fibrosis and Cirrhosis. | 2019 | Details |
| A11488 | 30875495 | Atherosclerosis | Statins and nonalcoholic fatty liver disease in the era of precision medicine: More friends than foes. | 2019 | Details |
| A11490 | 30875479 | Expert Rev Gastroenterol Hepatol | Pediatric NAFLD: an overview and recent developments in diagnostics and treatment. | 2019 | Details |
| A11496 | 30871368 | Exp Biol Med (Maywood) | Nonalcoholic fatty liver disease and the gut microbiome: Are bacteria responsible for fatty liver? | 2019 | Details |
| A11506 | 30867987 | PeerJ | Comparison of laboratory indices of non-alcoholic fatty liver disease for the detection of incipient kidney dysfunction. | 2019 | Details |
| A11511 | 30865013 | Am J Gastroenterol | Physical Activity, Fatty Liver, and Glucose Metabolism Over the Life Course: The Lifelines Cohort. | 2019 | Details |
| A11513 | 30864239 | J Gastroenterol Hepatol | Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis. | 2019 | Details |
| A11521 | 30860882 | Am J Physiol Endocrinol Metab | Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease. | 2019 | Details |
| A11524 | 30859582 | Hepatology | Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and Is Associated With Liver Fibrosis Assessed by Magnetic Resonance Elastography. | 2019 | Details |
| A11529 | 30855277 | J Clin Invest | Resolving inflammation in nonalcoholic steatohepatitis. | 2019 | Details |
| A11535 | 30853445 | Transl Res | Role of the intestinal microbiome in liver fibrosis development and new treatment strategies. | 2019 | Details |
| A11540 | 30851216 | Liver Int | Evaluating the association of serum ferritin and hepatic iron with disease severity in non-alcoholic fatty liver disease. | 2019 | Details |
| A11542 | 30850637 | Sci Rep | Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan. | 2019 | Details |
| A11547 | 30849036 | Cleve Clin J Med | Assessing liver fibrosis without biopsy in patients with HCV or NAFLD. | 2019 | Details |
| A11549 | 30848827 | J Clin Endocrinol Metab | Plasma Fibroblast Growth Factor 21 Is Associated With Severity of Nonalcoholic Steatohepatitis in Patients With Obesity and Type 2 Diabetes. | 2019 | Details |
| A11554 | 30842500 | Sci Rep | Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11557 | 30841472 | Biomed Pharmacother | Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue. | 2019 | Details |
| A11560 | 30839434 | Eur J Gastroenterol Hepatol | Serum cytokeratin-18 and its relation to liver fibrosis and steatosis diagnosed by FibroScan and controlled attenuation parameter in nonalcoholic fatty liver disease and hepatitis C virus patients. | 2019 | Details |
| A11561 | 30839326 | Am J Gastroenterol | Nonalcoholic Fatty Liver Disease: Identification and Management of High-Risk Patients. | 2019 | Details |
| A11568 | 30836450 | Aliment Pharmacol Ther | Derivation and validation of a cardiovascular risk score for prediction of major acute cardiovascular events in non-alcoholic fatty liver disease; the importance of an elevated mean platelet volume. | 2019 | Details |
| A11569 | 30835899 | J Leukoc Biol | Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis. | 2019 | Details |
| A11573 | 30834274 | Biomed Res Int | Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients. | 2019 | Details |
| A11576 | 30833154 | Endocrinol Diabetes Nutr (Engl Ed) | Inflammatory stress and altered angiogenesis evoked by very high-fat diets in mouse liver. | 2019 | Details |
| A11578 | 30832722 | Trials | Effects of vitamin D supplementation on liver fibrogenic factors in non-alcoholic fatty liver patients with steatohepatitis: study protocol for a randomized clinical trial. | 2019 | Details |
| A11586 | 30828861 | J Gastroenterol Hepatol | Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation. | 2019 | Details |
| A11587 | 30828530 | Adv Sci (Weinh) | Insights into the Epidemiology, Pathogenesis, and Therapeutics of Nonalcoholic Fatty Liver Diseases. | 2018 | Details |
| A11588 | 30827925 | Clin Res Hepatol Gastroenterol | Increased mortality in non-alcoholic fatty liver disease with chronic kidney disease is explained by metabolic comorbidities. | 2019 | Details |
| A11594 | 30825254 | Liver Int | MACK-3 (combination of hoMa, Ast and CK18): A promising novel biomarker for fibrotic non-alcoholic steatohepatitis. | 2019 | Details |
| A11595 | 30825110 | Dig Dis Sci | Antifibrotic Effects of 1,25(OH)2D3 on Nonalcoholic Steatohepatitis in Female Mice. | 2019 | Details |
| A11598 | 30824564 | Mol Syst Biol | Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease. | 2019 | Details |
| A11602 | 30823570 | Diseases | The Therapeutic Implications of the Gut Microbiome and Probiotics in Patients with NAFLD. | 2019 | Details |
| A11607 | 30821873 | J Gastroenterol Hepatol | Human amnion epithelial cells and their soluble factors reduce liver fibrosis in murine non-alcoholic steatohepatitis. | 2019 | Details |
| A11610 | 30820874 | Adv Ther | Haptoglobin 2-2 Genotype is Associated with More Advanced Disease in Subjects with Non-Alcoholic Steatohepatitis: A Retrospective Study. | 2019 | Details |
| A11611 | 30820265 | World J Hepatol | Bariatric surgery in patients with non-alcoholic fatty liver disease - from pathophysiology to clinical effects. | 2019 | Details |
| A11616 | 30818874 | Genes (Basel) | iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice. | 2019 | Details |
| A11617 | 30818824 | Nutrients | A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices. | 2019 | Details |
| A11622 | 30815083 | AMIA Annu Symp Proc | Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients. | 2018 | Details |
| A11632 | 30810332 | Rev Esp Enferm Dig | Analysis of the burden and variability in the management of NAFLD patients in the clinical practice: unifying the required criteria. | 2019 | Details |
| A11633 | 30810330 | Rev Esp Enferm Dig | Higher levels of serum uric acid influences hepatic damage in patients with non-alcoholic fatty liver disease (NAFLD). | 2019 | Details |
| A11638 | 30809789 | Semin Liver Dis | Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets. | 2019 | Details |
| A11639 | 30809540 | Biomed Res Int | Transient Elastography and Ultrasonography: Optimal Evaluation of Liver Fibrosis and Cirrhosis in Patients with Chronic Hepatitis B Concurrent with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11641 | 30809000 | Mod Pathol | Detection of DNA damage response in nonalcoholic fatty liver disease via p53-binding protein 1 nuclear expression. | 2019 | Details |
| A11642 | 30808572 | Dig Liver Dis | Association between non-invasive liver fibrosis scores and occurrence of health adverse outcomes in older people. | 2019 | Details |