Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17052 | 28027788 | Atherosclerosis | Non-alcoholic fatty liver disease and subclinical atherosclerosis: A comparison of metabolically- versus genetically-driven excess fat hepatic storage. | 2016 | Details |
| A17053 | 28027586 | Hepatology | Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis. | 2017 | Details |
| A17055 | 28025059 | J Hepatol | MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis. | 2016 | Details |
| A17058 | 28017785 | Mol Cell Endocrinol | Hepatic lipid metabolism and non-alcoholic fatty liver disease in aging. | 2016 | Details |
| A17061 | 28013023 | Semin Cell Dev Biol | Metabolic roles of poly(ADP-ribose) polymerases. | 2016 | Details |
| A17062 | 28012599 | Med Hypotheses | Blood oxidative stress (BLOS) is a secondary host defense system responding normally to anaerobic wound infection and inadvertently to dietary ultra-exogenous sulfide formation (USF). | 2016 | Details |
| A17067 | 28011892 | Gut | Adipose type I interferon signalling protects against metabolic dysfunction. | 2016 | Details |
| A17074 | 28007354 | Sleep Med | Gut epithelial barrier markers in patients with obstructive sleep apnea. | 2016 | Details |
| A17078 | 28003715 | J Clin Exp Hepatol | High-Fructose Intake Impairs the Hepatic Hypolipidemic Effects of a High-Fat Fish-Oil Diet in C57BL/6 Mice. | 2016 | Details |
| A17079 | 28002874 | J Gastroenterol Hepatol | High serum alanine aminotransferase is associated with the risk of colorectal adenoma in Korean men. | 2017 | Details |
| A17081 | 28001263 | Rev Assoc Med Bras (1992) | Current management of non-alcoholic fatty liver disease. | 2016 | Details |
| A17085 | 27999564 | Front Endocrinol (Lausanne) | Distinct Hepatic Macrophage Populations in Lean and Obese Mice. | 2016 | Details |
| A17089 | 27997977 | Semin Liver Dis | Regulation of Hepatocellular Fatty Acid Uptake in Mouse Models of Fatty Liver Disease with and without Functional Leptin Signaling: Roles of NfKB and SREBP-1C and the Effects of Spexin. | 2016 | Details |
| A17096 | 27995280 | Arch Toxicol | Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A17099 | 27992443 | PLoS One | Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD. | 2016 | Details |
| A17100 | 27992361 | J Pediatr Endocrinol Metab | Risk factors that affect metabolic health status in obese children. | 2017 | Details |
| A17103 | 27990792 | Minerva Endocrinol | Diabetes mellitus and non-alcoholic fatty liver disease: the thread of Ariadne. | 2016 | Details |
| A17107 | 27988872 | Drugs | Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer's Disease. | 2017 | Details |
| A17108 | 27988847 | Eur J Nutr | Calcium and vitamin D3 combinations improve fatty liver disease through AMPK-independent mechanisms. | 2016 | Details |
| A17113 | 27986169 | Semin Ultrasound CT MR | Hepatic Steatosis: Etiology, Patterns, and Quantification. | 2016 | Details |
| A17121 | 27981615 | Hepatology | Metabolic and histological implications of intrahepatic triglyceride content in nonalcoholic fatty liver disease. | 2017 | Details |
| A17127 | 27977757 | PLoS One | Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial. | 2016 | Details |
| A17129 | 27976635 | Saudi J Gastroenterol | Outcome of phlebotomy for treating nonalcoholic fatty liver disease: A systematic review and meta-analysis. | 2016 | Details |
| A17130 | 27974597 | Nutr Rev | What is the appropriate upper limit for added sugars consumption? | 2017 | Details |
| A17133 | 27973461 | Minerva Endocrinol | Bone metabolism in non-alcoholic fatty liver disease: vitamin D status and bone mineral density. | 2016 | Details |
| A17135 | 27973438 | Int J Mol Sci | Pathophysiology of Non Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17143 | 27959936 | PLoS One | A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. | 2016 | Details |
| A17147 | 27957247 | World J Hepatol | Bibliometric analysis of top 100 cited articles in nonalcoholic fatty liver disease research. | 2016 | Details |
| A17148 | 27957244 | World J Hepatol | Neglected features of lifestyle: Their relevance in non-alcoholic fatty liver disease. | 2016 | Details |
| A17151 | 27956794 | World J Gastroenterol | Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis. | 2016 | Details |
| A17157 | 27942596 | JCI Insight | Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. | 2016 | Details |
| A17158 | 27941940 | Nutr Diabetes | Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway. | 2016 | Details |
| A17159 | 27941355 | Curr Opin Infect Dis | Managing nonalcoholic fatty liver disease in patients living with HIV. | 2017 | Details |
| A17161 | 27939613 | Toxicol In Vitro | Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. | 2016 | Details |
| A17162 | 27939359 | Pharmacol Res | A story of metformin-butyrate synergism to control various pathological conditions as a consequence of gut microbiome modification: Genesis of a wonder drug? | 2016 | Details |
| A17164 | 27938560 | Zhonghua Gan Zang Bing Za Zhi | [Effect of targeted inhibition of hypoxia-inducible factor-1α by 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole on the progression of non-alcoholic fatty liver disease in rats]. | 2016 | Details |
| A17168 | 27936230 | PLoS One | The Circulating CTRP13 in Type 2 Diabetes and Non-Alcoholic Fatty Liver Patients. | 2016 | Details |
| A17170 | 27935258 | Mol Nutr Food Res | Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation. | 2017 | Details |
| A17173 | 27933201 | BMJ Open Gastroenterol | Association between metabolic syndrome and liver histology among NAFLD patients without diabetes. | 2016 | Details |
| A17177 | 27929200 | Thromb Haemost | Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans. | 2016 | Details |
| A17179 | 27928661 | J Bone Miner Metab | Nonalcoholic fatty liver disease and osteoporosis: a systematic review and meta-analysis. | 2016 | Details |
| A17182 | 27924915 | Sci Rep | Serum uric acid is independently and linearly associated with risk of nonalcoholic fatty liver disease in obese Chinese adults. | 2016 | Details |
| A17188 | 27921044 | Visc Med | Non-Alcoholic Fatty Liver Disease: Cause or Effect of Metabolic Syndrome. | 2016 | Details |
| A17189 | 27920819 | Res Pharm Sci | Co-administration of metformin and N-acetylcysteine with dietary control improves the biochemical and histological manifestations in rats with non-alcoholic fatty liver. | 2016 | Details |
| A17190 | 27920470 | World J Gastroenterol | Nonalcoholic fatty liver disease - A multisystem disease? | 2016 | Details |
| A17196 | 27917591 | Diabetes Obes Metab | The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism. | 2017 | Details |
| A17197 | 27917585 | Liver Int | The preventive effect of sustained physical activity on incident nonalcoholic fatty liver disease. | 2016 | Details |
| A17200 | 27916988 | Int J Obes (Lond) | Circulating sCD36 levels in patients with non-alcoholic fatty liver disease and controls. | 2016 | Details |
| A17201 | 27916783 | Endocr J | Reduction of visceral fat by liraglutide is associated with ameliorations of hepatic steatosis, albuminuria, and micro-inflammation in type 2 diabetic patients with insulin treatment: a randomized control trial. | 2016 | Details |
| A17203 | 27916420 | Biomed Pharmacother | Potential involvement of JNK1 repression in the hepatic effect of sitagliptin and metformin in rats subjected to high fat diet and chronic mild distress. | 2016 | Details |
| A17209 | 27913605 | Eur J Endocrinol | Non-alcoholic fatty liver disease is associated with early left ventricular dysfunction in childhood acute lymphoblastic leukaemia survivors. | 2017 | Details |
| A17214 | 27909908 | Recent Results Cancer Res | Obesity and Liver Cancer. | 2017 | Details |
| A17215 | 27909723 | Mol Med Rep | Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease. | 2016 | Details |
| A17216 | 27908750 | Transl Res | Mesenchymal stromal cell-based therapies reduce obesity and metabolic syndromes induced by a high-fat diet. | 2016 | Details |
| A17217 | 27908430 | J Trace Elem Med Biol | Evaluation of tissue metal and trace element content in a rat model of non-alcoholic fatty liver disease using ICP-DRC-MS. | 2016 | Details |
| A17219 | 27907824 | J Nutr Biochem | Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets. | 2016 | Details |
| A17220 | 27906700 | Curr Opin Clin Nutr Metab Care | Update on lipid species and paediatric nonalcoholic fatty liver disease. | 2017 | Details |
| A17223 | 27904677 | Am J Transl Res | An engineered FGF21 variant, LY2405319, can prevent non-alcoholic steatohepatitis by enhancing hepatic mitochondrial function. | 2016 | Details |
| A17235 | 27895587 | Front Physiol | Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. | 2016 | Details |
| A17236 | 27895422 | World J Gastroenterol | Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease. | 2016 | Details |
| A17238 | 27895393 | World J Gastroenterol | Emerging role of obeticholic acid in the management of nonalcoholic fatty liver disease. | 2016 | Details |
| A17241 | 27893783 | PLoS One | Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice. | 2016 | Details |
| A17242 | 27893763 | PLoS One | The Role of Morbid Obesity in the Promotion of Metabolic Disruptions and Non-Alcoholic Steatohepatitis by Helicobacter Pylori. | 2016 | Details |
| A17245 | 27891128 | Front Immunol | Immune Imbalances in Non-Alcoholic Fatty Liver Disease: From General Biomarkers and Neutrophils to Interleukin-17 Axis Activation and New Therapeutic Targets. | 2016 | Details |
| A17246 | 27890642 | Free Radic Biol Med | Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation. | 2016 | Details |
| A17249 | 27889912 | Acta Paediatr | Insulin-like growth factor 1 and metabolic parameters are associated with nonalcoholic fatty liver disease in obese children and adolescents. | 2017 | Details |
| A17250 | 27889809 | Diabetologia | Reversal of type 2 diabetes in youth who adhere to a very-low-energy diet: a pilot study. | 2016 | Details |
| A17255 | 27889327 | Mol Aspects Med | Epigenetics in non-alcoholic fatty liver disease. | 2016 | Details |
| A17259 | 27885258 | Sci Rep | Circulating periostin in relation to insulin resistance and nonalcoholic fatty liver disease among overweight and obese subjects. | 2016 | Details |
| A17267 | 27879962 | Minerva Endocrinol | Intestinal hormones, gut microbiota and non-alcoholic fatty liver disease. | 2016 | Details |
| A17269 | 27876064 | Lipids Health Dis | Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese mice. | 2016 | Details |
| A17273 | 27872642 | Int J Endocrinol | Rationale and Design of RNAFH Study: Effect of Rosuvastatin (10 mg/d) on Nonalcoholic Fatty Liver in Metabolic Syndrome Patients without Overt Diabetes Evaluated by 1H-Magnetic Resonance Spectroscopy. | 2016 | Details |
| A17293 | 27860427 | J Dig Dis | The role of ADIPOQ methylation in curcumin-administrated experimental nonalcoholic fatty liver disease. | 2016 | Details |
| A17294 | 27860077 | Pathol Int | Critical in vivo roles of histamine and histamine receptor signaling in animal models of metabolic syndrome. | 2016 | Details |
| A17297 | 27859493 | Clin Exp Pharmacol Physiol | Connexin32 deficiency is associated with liver injury, inflammation and oxidative stress in experimental non-alcoholic steatohepatitis. | 2017 | Details |
| A17302 | 27856635 | J Biol Chem | MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease: A NOVEL MOUSE MODEL OF OBESITY PARADOX. | 2016 | Details |
| A17310 | 27855315 | J Nutr Biochem | Dietary sphingomyelin attenuates hepatic steatosis and adipose tissue inflammation in high-fat-diet-induced obese mice. | 2016 | Details |
| A17312 | 27853271 | Sci Rep | Foetal programming by methyl donor deficiency produces steato-hepatitis in rats exposed to high fat diet. | 2016 | Details |
| A17313 | 27853246 | Sci Rep | Plasma selenium levels and nonalcoholic fatty liver disease in Chinese adults: a cross-sectional analysis. | 2016 | Details |
| A17314 | 27852946 | Postgrad Med J | Non-alcoholic fatty liver disease and colorectal cancer. | 2016 | Details |
| A17315 | 27852719 | BMJ Open | Gender differences in the association of non-alcoholic fatty liver disease and metabolic syndrome with erosive oesophagitis: a cross-sectional study in a Taiwanese population. | 2016 | Details |
| A17317 | 27851965 | Cell Rep | Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression. | 2016 | Details |
| A17326 | 27843095 | EBioMedicine | Branched Chain Amino Acids Cause Liver Injury in Obese/Diabetic Mice by Promoting Adipocyte Lipolysis and Inhibiting Hepatic Autophagy. | 2016 | Details |
| A17331 | 27837778 | Gastroenterol Clin North Am | Nonalcoholic Fatty Liver Disease: Pathophysiology and Management. | 2016 | Details |
| A17341 | 27834478 | Minerva Endocrinol | Iron overload and non-alcoholic fatty liver disease. | 2016 | Details |
| A17348 | 27831642 | Eur Rev Med Pharmacol Sci | Plasma pentraxin-3 is associated with endothelial dysfunction in non-alcoholic fatty liver disease. | 2016 | Details |
| A17351 | 27830836 | Sci Rep | Long-term lifestyle interventions in middle-aged and elderly men with nonalcoholic fatty liver disease: a randomized controlled trial. | 2016 | Details |
| A17354 | 27826704 | Hepatol Int | Serum-inducible protein (IP)-10 is a disease progression-related marker for non-alcoholic fatty liver disease. | 2016 | Details |
| A17360 | 27824430 | Drug Res (Stuttg) | Dietary Fructose-Induced Hepatic Injury in Male and Female Rats: Influence of Resveratrol. | 2016 | Details |
| A17364 | 27823604 | Endocrinol Metab Clin North Am | Nonalcoholic Fatty Liver Disease: The New Complication of Type 2 Diabetes Mellitus. | 2016 | Details |
| A17372 | 27821715 | Physiol Rep | A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for nonalcoholic steatohepatitis. | 2016 | Details |
| A17374 | 27818933 | Mol Metab | Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice. | 2016 | Details |
| A17385 | 27811231 | J Lipid Res | Genetic and hormonal control of hepatic steatosis in female and male mice. | 2016 | Details |
| A17386 | 27810989 | Diabetes Care | Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference. | 2016 | Details |
| A17390 | 27504850 | J Clin Endocrinol Metab | Retinol-Binding Protein 4 Induces Hepatic Mitochondrial Dysfunction and Promotes Hepatic Steatosis. | 2016 | Details |
| A17391 | 27459528 | J Clin Endocrinol Metab | One-Hour Postload Hyperglycemia Confers Higher Risk of Hepatic Steatosis to HbA1c-Defined Prediabetic Subjects. | 2016 | Details |
| A17395 | 27729660 | Nat Rev Gastroenterol Hepatol | NAFLD and diabetes mellitus. | 2016 | Details |
| A17401 | 27803497 | Med Sci Monit | Clinical Study of Serum Homocysteine and Non-Alcoholic Fatty Liver Disease in Euglycemic Patients. | 2016 | Details |
| A17402 | 27803297 | Clin Sci (Lond) | Defective adaptive thermogenesis contributes to metabolic syndrome and liver steatosis in obese mice. | 2016 | Details |
| A17407 | 27760050 | J Clin Invest | Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance. | 2016 | Details |