Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A51552 | 35233382 | J Clin Transl Hepatol | Biomarkers of Metabolic (Dysfunction)-associated Fatty Liver Disease: An Update. | 2021 | Details |
| A51571 | 35042855 | Nutr Diabetes | Metabolic biomarkers related to cardiac dysfunction in metabolic-dysfunction-associated fatty liver disease: a cross-sectional analysis. | 2022 | Details |
| A51582 | 34877669 | Aliment Pharmacol Ther | Skipping breakfast is associated with an increased long-term cardiovascular mortality in metabolic dysfunction-associated fatty liver disease (MAFLD) but not MAFLD-free individuals. | 2021 | Details |
| A51586 | 34768714 | J Clin Med | Relationship between Adipokines and Cardiovascular Ultrasound Parameters in Metabolic-Dysfunction-Associated Fatty Liver Disease. | 2021 | Details |
| A51595 | 35818826 | J Diabetes Investig | Abdominal aortic calcification is associated with Fib-4 index and low body mass index in type 2 diabetes: a retrospective cross-sectional study. | 2022 | Details |
| A51600 | 35753042 | Hepatology | Fatty liver disease is not associated with increased mortality in the elderly - A prospective cohort study. | 2022 | Details |
| A51616 | 35620719 | Front Med (Lausanne) | Predictive and Prognostic Roles of Gut Microbial Variation in Liver Transplant. | 2022 | Details |
| A51619 | 35574038 | Front Endocrinol (Lausanne) | Role of Innate lymphoid Cells in Obesity and Insulin Resistance. | 2022 | Details |
| A51621 | 35550438 | Drug Discov Today | Key regulatory miRNAs in lipid homeostasis: Implications for cardiometabolic diseases and development of novel therapeutics. | 2022 | Details |
| A51624 | 35508517 | Trends Endocrinol Metab | Diet- and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease. | 2022 | Details |
| A51630 | 35483558 | Biochim Biophys Acta Mol Cell Biol Lipids | The effect of black seed (Nigella sativa) extract on lipid metabolism in HepG2 cells. | 2022 | Details |
| A51641 | 35364299 | Mol Metab | Hepatic adropin is regulated by estrogen and contributes to adverse metabolic phenotypes in ovariectomized mice. | 2022 | Details |
| A51643 | 35316838 | Diabetes | When Adipose Tissue Lets You Down: Understanding the Functions of Genes Disrupted in Lipodystrophy. | 2022 | Details |
| A51644 | 35305637 | BMC Endocr Disord | Prevalence of prediabetes and associated factors in southwest iran: results from Hoveyzeh cohort study. | 2022 | Details |
| A51651 | 35268696 | Molecules | A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach. | 2022 | Details |
| A51654 | 35224857 | Liver Transpl | Results of a multidisciplinary strategy to improve the management of cardiovascular risk factors after liver transplantation. | 2022 | Details |
| A51660 | 35177220 | Am J Obstet Gynecol | Preeclampsia and eclampsia: the conceptual evolution of a syndrome. | 2022 | Details |
| A51663 | 35126841 | World J Hepatol | Metabolic and nutritional triggers associated with increased risk of liver complications in SARS-CoV-2. | 2022 | Details |
| A51670 | 35070008 | World J Hepatol | Gut dysbiosis and systemic inflammation promote cardiomyocyte abnormalities in an experimental model of steatohepatitis. | 2021 | Details |
| A51682 | 34958818 | Metabolism | The clustering of Cardiovascular, Renal, Adipo-Metabolic Eye and Liver disease with type 2 diabetes. | 2021 | Details |
| A51686 | 34920733 | Cardiovasc Diabetol | Pharmacometabolomic profiles in type 2 diabetic subjects treated with liraglutide or glimepiride. | 2021 | Details |
| A51695 | 34841293 | Cell Rep Med | Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia. | 2021 | Details |
| A51696 | 34836963 | Nat Commun | CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. | 2021 | Details |
| A51697 | 34829826 | Biomedicines | Osteopontin Gene Polymorphisms Are Associated with Cardiovascular Risk Factors in Patients with Premature Coronary Artery Disease. | 2021 | Details |
| A51708 | 34722722 | Visc Med | Obesity and Gallstones. | 2021 | Details |
| A51726 | 34571257 | Clin Gastroenterol Hepatol | Fatty Pancreas Is Independently Associated With Subsequent Diabetes Mellitus Development: A 10-Year Prospective Cohort Study. | 2021 | Details |
| A51732 | 34502295 | Int J Mol Sci | A-FABP in Metabolic Diseases and the Therapeutic Implications: An Update. | 2021 | Details |
| A51739 | 34447678 | J Clin Transl Hepatol | Metabolic-associated Fatty Liver Disease as Assessed by the Fatty Liver Index Among Migrant and Non-migrant Ghanaian Populations. | 2021 | Details |
| A51740 | 34444990 | Nutrients | Multifactorial Basis and Therapeutic Strategies in Metabolism-Related Diseases. | 2021 | Details |
| A51746 | 34409856 | Antioxid Redox Signal | Mitochondrial Adaptive Responses to Hypertriglyceridemia and Bioactive Lipids. | 2021 | Details |
| A51749 | 34408459 | Diabetes Metab Syndr Obes | Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease. | 2021 | Details |
| A51763 | 34289326 | Nord J Psychiatry | Hepatic steatosis in patients with schizophrenia: a clinical cross-sectional study. | 2021 | Details |
| A51783 | 34098336 | Environ Int | Lipid metabolism disorders associated with dioxin exposure in a cohort of Chinese male workers revealed by a comprehensive lipidomics study. | 2021 | Details |
| A51798 | 34019585 | PLoS One | FGF21 serum levels are related to insulin resistance, metabolic changes and obesity in Mexican people living with HIV (PLWH). | 2021 | Details |
| A51801 | 34013499 | Hu Li Za Zhi | [Nutritional Care in Acute and Chronic Illness]. | 2021 | Details |
| A51803 | 33990492 | J Acquir Immune Defic Syndr | Associations of Hepatosteatosis With Cardiovascular Disease in HIV-Positive and HIV-Negative Patients: The Liverpool HIV-Heart Project. | 2021 | Details |
| A51809 | 33957191 | Mol Cell Endocrinol | Retinol-binding protein 4 in obesity and metabolic dysfunctions. | 2021 | Details |
| A51813 | 33947390 | Cardiovasc Diabetol | Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double-blind placebo-controlled clinical trials. | 2021 | Details |
| A51826 | 33900312 | Food Funct | Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. | 2021 | Details |
| A51834 | 33833481 | World J Gastroenterol | Metabolic complications of hepatitis C virus infection. | 2021 | Details |
| A51836 | 33812885 | Eur J Pharmacol | JNK signaling pathway in metabolic disorders: An emerging therapeutic target. | 2021 | Details |
| A51837 | 33809061 | Cells | Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge. | 2021 | Details |
| A51846 | 33758341 | Int J Obes (Lond) | Developmental programming of offspring adipose tissue biology and obesity risk. | 2021 | Details |
| A51848 | 33746902 | Front Endocrinol (Lausanne) | The Impact of Gut Microbiome on Metabolic Disorders During Catch-Up Growth in Small-for-Gestational-Age. | 2021 | Details |
| A51852 | 33671067 | Int J Mol Sci | A Systems Biology Approach to Investigating the Interaction between Serotonin Synthesis by Tryptophan Hydroxylase and the Metabolic Homeostasis. | 2021 | Details |
| A51854 | 33652692 | Antioxidants (Basel) | Propolis in Metabolic Syndrome and Its Associated Chronic Diseases: A Narrative Review. | 2021 | Details |
| A51866 | 33577395 | Metab Syndr Relat Disord | Usefulness of Triglyceride to High-Density Lipoprotein Ratio and Alanine Aminotransferase for Predicting Insulin Resistance and Metabolic Syndrome in the Japanese Population. | 2021 | Details |
| A51875 | 33514384 | Lipids Health Dis | The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial. | 2021 | Details |
| A51877 | 33499382 | Nutrients | Rind from Purple Mangosteen (Garcinia mangostana) Attenuates Diet-Induced Physiological and Metabolic Changes in Obese Rats. | 2021 | Details |
| A51884 | 33470195 | Am Heart J | Rationale and design of the CLEAR-outcomes trial: Evaluating the effect of bempedoic acid on cardiovascular events in patients with statin intolerance. | 2020 | Details |
| A51887 | 33454435 | Biochim Biophys Acta Mol Cell Biol Lipids | Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. | 2021 | Details |
| A51893 | 33419028 | J Clin Med | Hypertension and Its Associations with Dental Status: Data from the Dental, Oral, Medical Epidemiological (DOME) Nationwide Records-Based Study. | 2021 | Details |
| A51903 | 33339817 | Nat Commun | Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. | 2020 | Details |
| A51907 | 33304629 | Curr Health Sci J | Facing the Unseen - Metabolic Syndrome in Psoriatic Arthritis. | 2020 | Details |
| A51910 | 33298113 | J Transl Med | Precision medicine in the era of artificial intelligence: implications in chronic disease management. | 2020 | Details |
| A51911 | 33296241 | Environ Health Perspect | In Vivo Characterization of the Toxicological Properties of DPhP, One of the Main Degradation Products of Aryl Phosphate Esters. | 2020 | Details |
| A51914 | 33273564 | Sci Rep | Short-term Cudrania tricuspidata fruit vinegar administration attenuates obesity in high-fat diet-fed mice by improving fat accumulation and metabolic parameters. | 2020 | Details |
| A51915 | 33273482 | Sci Rep | NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet. | 2020 | Details |
| A51923 | 33221593 | Environ Int | Systems toxicogenomics of prenatal low-dose BPA exposure on liver metabolic pathways, gut microbiota, and metabolic health in mice. | 2020 | Details |
| A51935 | 33083279 | Liver Cancer | Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. | 2020 | Details |
| A51937 | 33078304 | Arch Pharm Res | Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases. | 2020 | Details |
| A51945 | 33007919 | J Clin Med | SOS Teeth: First Priority Teeth with Advanced Caries and Its Associations with Metabolic Syndrome among a National Representative Sample of Young and Middle-Aged Adults. | 2020 | Details |
| A51946 | 33006467 | Minerva Endocrinol | Insulin resistance and hepatic steatosis in type 1 diabetes mellitus and their association with diabetic chronic complications. | 2020 | Details |
| A51961 | 32872598 | J Clin Med | Whole-Body Cryotherapy Is an Effective Method of Reducing Abdominal Obesity in Menopausal Women with Metabolic Syndrome. | 2020 | Details |
| A51968 | 32814419 | Endocrinol Metab (Seoul) | Metabolically Healthy and Unhealthy Normal Weight and Obesity. | 2020 | Details |
| A51973 | 32712422 | Environ Int | Serum metabolic changes associated with dioxin exposure in a Chinese male cohort. | 2020 | Details |
| A51978 | 32663609 | Biochim Biophys Acta Mol Cell Biol Lipids | Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD. | 2020 | Details |
| A51993 | 32534728 | Clin Investig Arterioscler | Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study. | 2020 | Details |
| A51994 | 32534424 | J Nutr Biochem | Association between 12α-hydroxylated bile acids and hepatic steatosis in rats fed a high-fat diet. | 2020 | Details |
| A51999 | 32483543 | Pediatr Gastroenterol Hepatol Nutr | Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome. | 2020 | Details |
| A52001 | 32478901 | J Food Biochem | Hypolipidemic and antioxidant activities of Trichosanthes kirilowii maxim seed oil and flavonoids in mice fed with a high-fat diet. | 2020 | Details |
| A52012 | 32303571 | Dis Model Mech | A comprehensive study of phospholipid fatty acid rearrangements in metabolic syndrome: correlations with organ dysfunction. | 2020 | Details |
| A52018 | 32245824 | BMJ Open Diabetes Res Care | Relationship of obesity to adipose tissue insulin resistance. | 2020 | Details |
| A52020 | 32229290 | Clin Immunol | Comorbidities associated with psoriatic arthritis: Review and update. | 2020 | Details |
| A52024 | 32198195 | Diabetes | Exercise Combats Hepatic Steatosis: Potential Mechanisms and Clinical Implications. | 2020 | Details |
| A52031 | 32125846 | J Agric Food Chem | Chemistry of Pterostilbene and Its Metabolic Effects. | 2020 | Details |
| A52032 | 32120465 | Ceylon Med J | Association of Serum Uric acid and Gamma-glutamyltransferase with Obesity Related Metabolic Derangements in a Cohort of Children with Obesity in Sri Lanka | 2019 | Details |
| A52035 | 32069304 | PLoS One | Irisin and markers of metabolic derangement in non-diabetic Caucasian subjects with stage I-II obesity during early aging. | 2020 | Details |
| A52037 | 32039990 | Curr Opin Lipidol | Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular disease. | 2020 | Details |
| A52042 | 31972148 | Clin Biochem | Circulating PCSK9 is associated with liver biomarkers and hepatic steatosis. | 2020 | Details |
| A52050 | 31892362 | Clin Epigenetics | Obesity-induced nucleosome release predicts poor cardio-metabolic health. | 2019 | Details |
| A52052 | 31888081 | Nutrients | Yarrow Supercritical Extract Ameliorates the Metabolic Stress in a Model of Obesity Induced by High-Fat Diet. | 2019 | Details |
| A52058 | 31786232 | Biochimie | Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention. | 2019 | Details |
| A52066 | 31696832 | Lancet Gastroenterol Hepatol | The association between dietary fibre deficiency and high-income lifestyle-associated diseases: Burkitt's hypothesis revisited. | 2019 | Details |
| A52069 | 31676981 | Diabetologia | Circulating palmitoleic acid is an independent determinant of insulin sensitivity, beta cell function and glucose tolerance in non-diabetic individuals: a longitudinal analysis. | 2019 | Details |
| A52075 | 31656583 | F1000Res | Recent advances in understanding lipodystrophy: a focus on lipodystrophy-associated cardiovascular disease and potential effects of leptin therapy on cardiovascular function. | 2019 | Details |
| A52078 | 31592400 | Diabetol Int | Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity. | 2019 | Details |
| A52084 | 31554181 | Nutrients | Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1). | 2019 | Details |
| A52092 | 31340878 | Proc Nutr Soc | Different physiological mechanisms underlie an adverse cardiovascular disease risk profile in men and women. | 2019 | Details |
| A52093 | 31311771 | DNA Repair (Amst) | Roles of OGG1 in transcriptional regulation and maintenance of metabolic homeostasis. | 2019 | Details |
| A52099 | 31275580 | BMJ Open Gastroenterol | Association of fatty liver disease with mortality outcomes in an Eastern Finland male cohort. | 2019 | Details |
| A52104 | 31184331 | Rev Invest Clin | NUTRIGENOMICS AS A TOOL IN THE PREVENTION OF LIPOTOXICITY: THE CASE OF SOY PROTEIN. | 2019 | Details |
| A52110 | 31091691 | Nutrients | Preventive Effects of the Marine Microalga Phaeodactylum tricornutum, Used as a Food Supplement, on Risk Factors Associated with Metabolic Syndrome in Wistar Rats. | 2019 | Details |
| A52113 | 31073969 | J Endocrinol Invest | Sick fat: the good and the bad of old and new circulating markers of adipose tissue inflammation. | 2019 | Details |
| A52122 | 30979683 | J Cyst Fibros | Cystic fibrosis dyslipidaemia: A cross-sectional study. | 2019 | Details |
| A52124 | 30972920 | Physiol Rep | Resistance to visceral obesity is associated with increased locomotion in mice expressing an endothelial cell-specific fibroblast growth factor 1 transgene. | 2019 | Details |
| A52125 | 30971183 | Circ Res | Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk. | 2019 | Details |
| A52130 | 30921498 | Mol Nutr Food Res | Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low-Density Lipoprotein Receptor-Deficient Mice. | 2019 | Details |
| A52138 | 30816800 | Arterioscler Thromb Vasc Biol | Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State. | 2019 | Details |
| A52142 | 30766812 | Indian J Endocrinol Metab | Evaluation of Proinflammatory Cytokines in Obese vs Non-obese Patients with Metabolic Syndrome. | 2022 | Details |