Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A37576 | 15331068 | Clin Liver Dis | Lipid metabolism in hepatic steatosis. | 2004 | Details |
| A37635 | 15223984 | Diabetes Metab | The ins and outs of mitochondrial dysfunction in NASH. | 2004 | Details |
| A37868 | 12907343 | Am J Gastroenterol | Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis. | 2003 | Details |
| A37882 | 12869892 | J Clin Gastroenterol | Serum lipids, lipoproteins and apolipoproteins levels in patients with nonalcoholic steatohepatitis. | 2003 | Details |
| A37897 | 12830008 | Hepatology | Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis. | 2003 | Details |
| A38068 | 12353383 | Eksp Klin Gastroenterol | [Clinico-morphological changes of the liver in patients with dyslipoproteinemia]. | 2002 | Details |
| A38186 | 11944630 | Semin Gastrointest Dis | Diabetes mellitus, obesity, and hepatic steatosis. | 2002 | Details |
| A38220 | 11873108 | J Clin Gastroenterol | Update on nonalcoholic fatty liver disease. | 2002 | Details |
| A38248 | 11768156 | Lipids | Postprandial triglyceride-rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients. | 2001 | Details |
| A38336 | 11513189 | Am J Gastroenterol | Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis. | 2001 | Details |
| A42235 | 35136038 | Cell Death Dis | The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders. | 2022 | Details |
| A42274 | 35022960 | Mol Cell Biochem | Autophagy: a molecular switch to regulate adipogenesis and lipolysis. | 2022 | Details |
| A42289 | 34964947 | J Microbiol | The human symbiont Bacteroides thetaiotaomicron promotes diet-induced obesity by regulating host lipid metabolism. | 2021 | Details |
| A42337 | 34825869 | Curr Drug Metab | Regulatory Effects of N-3 PUFAs on Pancreatic β-cells and Insulin-sensitive Tissues. | 2021 | Details |
| A42362 | 34764874 | Front Pharmacol | Carnitine Palmitoyltransferase System: A New Target for Anti-Inflammatory and Anticancer Therapy? | 2021 | Details |
| A42430 | 34542351 | Crit Rev Food Sci Nutr | Branched chain amino acids-friend or foe in the control of energy substrate turnover and insulin sensitivity? | 2021 | Details |
| A42433 | 34532001 | Food Sci Nutr | L-citrulline inhibits body weight gain and hepatic fat accumulation by improving lipid metabolism in a rat nonalcoholic fatty liver disease model. | 2021 | Details |
| A42455 | 34496266 | J Ethnopharmacol | Xiaoyao San attenuates hepatic steatosis through estrogen receptor α pathway in ovariectomized ApoE-/- mice. | 2021 | Details |
| A42477 | 34436472 | Metabolites | The Role of Gut Microbiota and Its Produced Metabolites in Obesity, Dyslipidemia, Adipocyte Dysfunction, and Its Interventions. | 2021 | Details |
| A42487 | 34402268 | Zhongguo Zhong Yao Za Zhi | [Efficacy and mechanism of new resource medicinal materia Moringa oleifera leaves against hyperlipidemia]. | 2021 | Details |
| A42504 | 34358714 | Cell Mol Gastroenterol Hepatol | Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling. | 2021 | Details |
| A42518 | 34305616 | Front Pharmacol | Multi-Pharmacology of Berberine in Atherosclerosis and Metabolic Diseases: Potential Contribution of Gut Microbiota. | 2021 | Details |
| A42519 | 34292103 | Crit Rev Food Sci Nutr | Prebiotic inulin as a treatment of obesity related nonalcoholic fatty liver disease through gut microbiota: a critical review. | 2021 | Details |
| A42522 | 34278171 | Hepatol Commun | Hepatic Steatosis and Ectopic Fat Are Associated With Differences in Subcutaneous Adipose Tissue Gene Expression in People With HIV. | 2021 | Details |
| A42539 | 34207318 | Int J Mol Sci | Aberrations in Lipid Expression and Metabolism in Psoriasis. | 2021 | Details |
| A42542 | 34193189 | Nutr Metab (Lond) | Metabolomic signatures for liver tissue and cecum contents in high-fat diet-induced obese mice based on UHPLC-Q-TOF/MS. | 2021 | Details |
| A42560 | 34162770 | Biomol Ther (Seoul) | Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders. | 2021 | Details |
| A42568 | 34146880 | Chemosphere | Hepatotoxicity in carp (Cyprinus carpio) exposed to environmental levels of norfloxacin (NOR): Some latest evidences from transcriptomics analysis, biochemical parameters and histopathological changes. | 2021 | Details |
| A42592 | 34082043 | Biochimie | Roles of microRNAs in carbohydrate and lipid metabolism disorders and their therapeutic potential. | 2021 | Details |
| A42611 | 34023388 | J Biol Chem | Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice. | 2021 | Details |
| A42638 | 33933727 | Clin Nutr | Gender and gut microbiota composition determine hepatic bile acid, metabolic and inflammatory response to a single fast-food meal in healthy adults. | 2021 | Details |
| A42654 | 33869980 | J Endocr Soc | Removal of Epididymal Visceral Adipose Tissue Prevents Obesity-Induced Multi-organ Insulin Resistance in Male Mice. | 2021 | Details |
| A42674 | 33826777 | Hepatology | New Glance at the Role of TM6SF2 in Lipid Metabolism and Liver Cancer. | 2021 | Details |
| A42698 | 33728291 | Can J Gastroenterol Hepatol | Liver Cancer: Therapeutic Challenges and the Importance of Experimental Models. | 2021 | Details |
| A42706 | 33693864 | J Nutr | Milk Fat Globule Membrane Supplementation During Suckling Ameliorates Maternal High Fat Diet-Induced Hepatic Steatosis in Adult Male Offspring of Mice. | 2021 | Details |
| A42710 | 33681679 | Hepatol Commun | Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα-FGF21 Axis. | 2020 | Details |
| A42734 | 33608424 | Diabetes | Regulation of Hepatic Metabolism and Cell Growth by the ATF/CREB Family of Transcription Factors. | 2021 | Details |
| A42736 | 33604315 | J Hepatocell Carcinoma | Mechanisms Underlying Hepatocellular Carcinoma Progression in Patients with Type 2 Diabetes. | 2021 | Details |
| A42748 | 33586679 | J Clin Invest | Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis. | 2021 | Details |
| A42768 | 33527946 | Food Funct | Uridine attenuates obesity, ameliorates hepatic lipid accumulation and modifies the gut microbiota composition in mice fed with a high-fat diet. | 2021 | Details |
| A42777 | 33505493 | Evid Based Complement Alternat Med | Use of Network Pharmacology to Investigate the Mechanism by Which Allicin Ameliorates Lipid Metabolism Disorder in HepG2 Cells. | 2021 | Details |
| A42778 | 33500723 | Theranostics | Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism. | 2021 | Details |
| A42789 | 33471689 | Endocr Pract | Role of Androgen in Liver Fat Content in Women: Metabolically Advantageous or Disadvantageous? | 2020 | Details |
| A42819 | 33353459 | Thyroid | Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta. | 2021 | Details |
| A42820 | 33347955 | Mol Cell Endocrinol | RORα regulates hepatic lipolysis by inducing transcriptional expression of PNPLA3 in mice. | 2020 | Details |
| A42845 | 33309167 | J Genet Genomics | Comprehensive lipidomics in apoM-/- mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation. | 2020 | Details |
| A42874 | 33247737 | Toxicol Sci | Inhibition of Acetyl-CoA Carboxylase Causes Malformations in Rats and Rabbits: Comparison of Mammalian Findings and Alternative Assays. | 2021 | Details |
| A42907 | 33142445 | Poult Sci | Maintaining intestinal structural integrity is a potential protective mechanism against inflammation in goose fatty liver. | 2020 | Details |
| A42908 | 33142057 | J Med Chem | A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities. | 2020 | Details |
| A42912 | 33123088 | Front Endocrinol (Lausanne) | The Impact of Adipose Tissue-Derived miRNAs in Metabolic Syndrome, Obesity, and Cancer. | 2020 | Details |
| A42913 | 33117357 | Front Immunol | Role of the Nuclear Receptor Corepressor 1 (NCOR1) in Atherosclerosis and Associated Immunometabolic Diseases. | 2020 | Details |
| A42933 | 33045592 | Environ Pollut | 4-Hexylphenol influences adipogenic differentiation and hepatic lipid accumulation in vitro. | 2020 | Details |
| A43024 | 32781719 | Biomolecules | Not So Slim Anymore-Evidence for the Role of SUMO in the Regulation of Lipid Metabolism. | 2020 | Details |
| A43025 | 32780879 | Hepatology | Multiple Parallel Hits Hypothesis in Nonalcoholic Fatty Liver Disease: Revisited After a Decade. | 2021 | Details |
| A43034 | 32755308 | Am J Physiol Gastrointest Liver Physiol | Microbiota on biotics: probiotics, prebiotics, and synbiotics to optimize growth and metabolism. | 2020 | Details |
| A43053 | 32693115 | J Ethnopharmacol | A review of the processed Polygonum multiflorum (Thunb.) for hepatoprotection: Clinical use, pharmacology and toxicology. | 2020 | Details |
| A43059 | 32680469 | BMC Gastroenterol | Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis. | 2020 | Details |
| A43095 | 32585124 | Appl Physiol Nutr Metab | Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice. | 2020 | Details |
| A43107 | 32553811 | Eur J Pharmacol | The effect of emodin on liver disease -- comprehensive advances in molecular mechanisms. | 2020 | Details |
| A43111 | 32532017 | Int J Mol Sci | Genomic and Non-Genomic Mechanisms of Action of Thyroid Hormones and Their Catabolite 3,5-Diiodo-L-Thyronine in Mammals. | 2020 | Details |
| A43141 | 32443199 | Environ Pollut | Lipidomics insight into chronic exposure to ambient air pollution in mice. | 2020 | Details |
| A43145 | 32431189 | J Am Heart Assoc | Fibroblast Growth Factor 21 is Related to Atherosclerosis Independent of Nonalcoholic Fatty Liver Disease and Predicts Atherosclerotic Cardiovascular Events. | 2020 | Details |
| A43153 | 32419825 | Evid Based Complement Alternat Med | Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation. | 2020 | Details |
| A43173 | 32374328 | Biomater Sci | A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection. | 2020 | Details |
| A43194 | 32335802 | Front Med | Biological properties and clinical applications of berberine. | 2020 | Details |
| A43197 | 32331890 | J Dairy Sci | Sirtuin 3 improves fatty acid metabolism in response to high nonesterified fatty acids in calf hepatocytes by modulating gene expression. | 2020 | Details |
| A43200 | 32318746 | J Mol Med (Berl) | Fructose metabolism by the guts cuts liver fat. | 2020 | Details |
| A43201 | 32316687 | Nutrients | Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation. | 2020 | Details |
| A43246 | 32184272 | Diabetes | Branched-Chain Amino Acids Exacerbate Obesity-Related Hepatic Glucose and Lipid Metabolic Disorders via Attenuating Akt2 Signaling. | 2020 | Details |
| A43248 | 32181687 | DNA Cell Biol | DES1: A Key Driver of Lipotoxicity in Metabolic Disease. | 2020 | Details |
| A43270 | 32107051 | J Hepatol | Two cases of non-alcoholic fatty liver disease caused by biallelic ABHD5 mutations. | 2020 | Details |
| A43307 | 32012270 | J Cell Physiol | Effects of different fatty acids on BRL3A rat liver cell damage. | 2020 | Details |
| A43366 | 31901629 | Environ Res | Global liver proteomic analysis of Wistar rats chronically exposed to low-levels of bisphenol A and S. | 2019 | Details |
| A43376 | 31883530 | Lipids Health Dis | A novel mutation of ABHD5 gene in a Chanarin Dorfman patient with unusual dermatological findings. | 2019 | Details |
| A43389 | 31851339 | J Nutr | Dietary Choline Supplementation Attenuates High-Fat-Diet-Induced Hepatocellular Carcinoma in Mice. | 2020 | Details |
| A43425 | 31754898 | Curr Diab Rep | Hyperglycemia During Pregnancy and Long-Term Offspring Outcomes. | 2019 | Details |
| A43429 | 31737665 | Biomed Res Int | Lipid Metabolism Alterations in a Rat Model of Chronic and Intergenerational Exposure to Arsenic. | 2019 | Details |
| A43500 | 31576746 | Chem Res Toxicol | Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats. | 2019 | Details |
| A43535 | 31483154 | Am J Physiol Regul Integr Comp Physiol | Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity. | 2019 | Details |
| A43544 | 31453710 | Am J Physiol Endocrinol Metab | Gestational hypercholesterolemia alters fetal hepatic lipid metabolism and microRNA expression in Apo-E-deficient mice. | 2019 | Details |
| A43552 | 31434739 | J Biol Chem | Sex-specific hepatic lipid and bile acid metabolism alterations in Fancd2-deficient mice following dietary challenge. | 2019 | Details |
| A43560 | 31408938 | Molecules | Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1. | 2019 | Details |
| A43582 | 31355732 | Zebrafish | Palmitic Acid-Enriched Diet Induces Hepatic Steatosis and Injury in Adult Zebrafish. | 2019 | Details |
| A43583 | 31355355 | Contact (Thousand Oaks) | Catching Lipid Droplet Contacts by Proteomics. | 2019 | Details |
| A43587 | 31345023 | J Agric Food Chem | Processed Meat Protein Promoted Inflammation and Hepatic Lipogenesis by Upregulating Nrf2/Keap1 Signaling Pathway in Glrx-Deficient Mice. | 2019 | Details |
| A43590 | 31341105 | JCI Insight | Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder. | 2019 | Details |
| A43591 | 31337282 | Thyroid | A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia. | 2019 | Details |
| A43607 | 31300671 | Sci Rep | Insulin resistance and metabonomics analysis of fatty liver haemorrhagic syndrome in laying hens induced by a high-energy low-protein diet. | 2019 | Details |
| A43613 | 31290314 | J Proteome Res | Lipidomics Reveals Similar Changes in Serum Phospholipid Signatures of Overweight and Obese Pediatric Subjects. | 2019 | Details |
| A43628 | 31253430 | J Pharmacol Sci | A novel AMPK activator improves hepatic lipid metabolism and leukocyte trafficking in experimental hepatic steatosis. | 2019 | Details |
| A43639 | 31237448 | Am J Physiol Endocrinol Metab | Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes. | 2019 | Details |
| A43640 | 31234250 | Clin Mol Hepatol | Carnitine palmitoyl transferase 1A deficiency in an adult with recurrent severe steato hepatitis aggravated by high pathologic or physiologic demands: A roller-coaster for internists. | 2019 | Details |
| A43663 | 31160717 | Cell Death Differ | SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity. | 2019 | Details |
| A43673 | 31137678 | Int J Mol Sci | Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition. | 2019 | Details |
| A43683 | 31106419 | J Cell Physiol | Impact of different ectopic fat depots on cardiovascular and metabolic diseases. | 2019 | Details |
| A43716 | 31048404 | J Lipid Res | Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption. | 2019 | Details |
| A43719 | 31030166 | J Nutr Biochem | High-fructose drinks affect microRNAs expression differently in lean and obese mice. | 2019 | Details |
| A43722 | 31023527 | Biochem Biophys Res Commun | Oleate inhibits hepatic autophagy through p38 mitogen-activated protein kinase (MAPK). | 2019 | Details |
| A43735 | 31000821 | Lab Anim (NY) | Predicting and reducing hepatic lipotoxicity in non-alcoholic fatty liver disease. | 2019 | Details |
| A43783 | 30890204 | Gene Expr | Sterol 12α-Hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP-1C Pathway via FGF21 and FGF15. | 2019 | Details |