Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A13137 | 30120929 | Toxicology | Modulation of xenobiotic nuclear receptors in high-fat diet induced non-alcoholic fatty liver disease. | 2018 | Details |
| A13141 | 30120404 | Pediatr Res | In a pilot study, reduced fatty acid desaturase 1 function was associated with nonalcoholic fatty liver disease and response to treatment in children. | 2018 | Details |
| A13143 | 30120271 | Sci Rep | An Evaluation of the Collagen Fragments Related to Fibrogenesis and Fibrolysis in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13149 | 30114411 | Life Sci | C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis. | 2018 | Details |
| A13151 | 30113367 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease: current concepts, epidemiology and management strategies. | 2018 | Details |
| A13153 | 30112518 | Curr Opin Gynecol Obstet | The Association of Hispanic Ethnicity with Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome. | 2018 | Details |
| A13158 | 30111756 | J Clin Med | Simple Scores of Fibrosis and Mortality in Patients with NAFLD: A Systematic Review with Meta-Analysis. | 2018 | Details |
| A13162 | 30106985 | PLoS One | Noninvasive scoring systems predict hepatic and extra-hepatic cancers in patients with nonalcoholic fatty liver disease. | 2018 | Details |
| A13174 | 30100243 | Mol Metab | Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context. | 2018 | Details |
| A13175 | 30099968 | BMC Med | Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease. | 2018 | Details |
| A13185 | 30096384 | Life Sci | Gut inflammation exacerbates hepatic injury in the high-fat diet induced NAFLD mouse: Attention to the gut-vascular barrier dysfunction. | 2018 | Details |
| A13190 | 30092894 | J Clin Sleep Med | Continuous Positive Airway Pressure Therapy on Nonalcoholic Fatty Liver Disease in Patients With Obstructive Sleep Apnea. | 2018 | Details |
| A13191 | 30092856 | Gene Expr | Stress of Strains: Inbred Mice in Liver Research. | 2018 | Details |
| A13194 | 30091925 | J Proteome Res | Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model. | 2018 | Details |
| A13196 | 30090738 | Indian J Endocrinol Metab | Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus. | 2020 | Details |
| A13198 | 30090613 | Toxicol Res (Camb) | Role of xenobiotics in the induction and progression of fatty liver disease. | 2018 | Details |
| A13199 | 30089858 | Lab Invest | Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis. | 2018 | Details |
| A13202 | 30087027 | Hepatobiliary Pancreat Dis Int | Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population. | 2018 | Details |
| A13204 | 30086613 | Clin Mol Hepatol | Recent research trends and updates on nonalcoholic fatty liver disease. | 2018 | Details |
| A13209 | 30083132 | Front Endocrinol (Lausanne) | Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis. | 2018 | Details |
| A13213 | 30080818 | Transplantation | Should Patients With NAFLD/NASH Be Surveyed for HCC? | 2019 | Details |
| A13216 | 30077785 | Clin Gastroenterol Hepatol | Importance of Evaluating Cardiovascular Risk and Hepatic Fibrosis in Patients With Newly Diagnosed Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13225 | 30075104 | Am J Med | Ideal Cardiovascular Health Is Inversely Associated with Nonalcoholic Fatty Liver Disease: A Prospective Analysis. | 2018 | Details |
| A13226 | 30074820 | Br J Radiol | Non-alcoholic fatty liver disease-associated hepatocellular carcinoma: effect of hepatic steatosis on major hepatocellular carcinoma features at MRI. | 2018 | Details |
| A13240 | 30068662 | Gut | Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis. | 2018 | Details |
| A13241 | 30068362 | J Transl Med | MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits. | 2018 | Details |
| A13242 | 30068065 | Clin Mol Hepatol | The Association of leptin with severity of non-alcoholic fatty liver disease: A population-based study. | 2018 | Details |
| A13244 | 30066228 | Infection | Endotoxinemia contributes to steatosis, insulin resistance and atherosclerosis in chronic hepatitis C: the role of pro-inflammatory cytokines and oxidative stress. | 2018 | Details |
| A13247 | 30065651 | Front Pharmacol | A Genetic Score Associates With Pioglitazone Response in Patients With Non-alcoholic Steatohepatitis. | 2018 | Details |
| A13250 | 30064623 | Ugeskr Laeger | [Treatment of non-alcoholic fatty liver disease]. | 2018 | Details |
| A13251 | 30063751 | PLoS One | Expression of insulin-like growth factor I and its receptor in the liver of children with biopsy-proven NAFLD. | 2018 | Details |
| A13254 | 30063256 | Hepatology | Dual-Specificity Phosphatase 9 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through ASK1 Suppression. | 2018 | Details |
| A13258 | 30060808 | Adv Cancer Res | Sphingolipids at the Crossroads of NAFLD and Senescence. | 2018 | Details |
| A13268 | 30059671 | Gastroenterology | GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13272 | 30057598 | Gastroenterol Res Pract | Steatohepatitis Is Not Associated with an Increased Risk for Fibrosis Progression in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13274 | 30056271 | Redox Biol | Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy. | 2018 | Details |
| A13275 | 30055803 | Biochem Biophys Res Commun | Autophagy is involved in acetylshikonin ameliorating non-alcoholic steatohepatitis through AMPK/mTOR pathway. | 2018 | Details |
| A13278 | 30054551 | Sci Rep | Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin. | 2018 | Details |
| A13279 | 30053055 | J Clin Endocrinol Metab | CXC Motif Ligand 16 Promotes Nonalcoholic Fatty Liver Disease Progression via Hepatocyte-Stellate Cell Crosstalk. | 2018 | Details |
| A13281 | 30052309 | Diabetes Metab Res Rev | Serum leptin and leptin resistance correlations with NAFLD in patients with type 2 diabetes. | 2018 | Details |
| A13284 | 30051943 | Hepatol Res | Effect of luseogliflozin on hepatic fat content in type 2 diabetes patients with non-alcoholic fatty liver disease: A prospective, single-arm trial (LEAD trial). | 2018 | Details |
| A13290 | 30048963 | Dig Dis | Sarcopenia Contributes to the Progression of Nonalcoholic Fatty Liver Disease- Related Fibrosis: A Meta-Analysis. | 2018 | Details |
| A13291 | 30048367 | Eur J Gastroenterol Hepatol | Non-alcoholic fatty liver disease and hypertension: coprevalent or correlated? | 2018 | Details |
| A13302 | 30042031 | Med Eng Phys | Role of acoustic radiation force impulse imaging elastography in the assessment of steatohepatitis and fibrosis in rat models. | 2018 | Details |
| A13303 | 30041934 | J Pediatr | Assessment of Nonalcoholic Fatty Liver Disease Progression in Children Using Magnetic Resonance Imaging. | 2018 | Details |
| A13313 | 30036883 | Cell Physiol Biochem | Regulatory Role of Endothelial PHD2 in the Hepatic Steatosis. | 2018 | Details |
| A13314 | 30036865 | Cell Physiol Biochem | Cangju Qinggan Jiangzhi Decoction Reduces the Development of NonAlcoholic Steatohepatitis and Activation of Kupffer Cells. | 2018 | Details |
| A13317 | 30034912 | Liver Res | FOXO transcription factors in non-alcoholic fatty liver disease. | 2017 | Details |
| A13321 | 30032630 | Rev Esp Enferm Dig | Role of the PNPLA3 polymorphism rs738409 on silymarin + vitamin E response in subjects with non-alcoholic fatty liver disease. | 2018 | Details |
| A13323 | 30032383 | Abdom Radiol (NY) | Reference range of liver corrected T1 values in a population at low risk for fatty liver disease-a UK Biobank sub-study, with an appendix of interesting cases. | 2019 | Details |
| A13324 | 30031769 | Gastroenterology | Association Between Magnetic Resonance Imaging-Proton Density Fat Fraction and Liver Histology Features in Patients With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13326 | 30030064 | Life Sci | Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients. | 2018 | Details |
| A13327 | 30029691 | Cardiovasc Diabetol | Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats. | 2018 | Details |
| A13332 | 30027137 | Hepatol Commun | Management of nonalcoholic fatty liver disease: Lessons learned from type 2 diabetes. | 2018 | Details |
| A13337 | 30026388 | Cold Spring Harb Mol Case Stud | Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease. | 2018 | Details |
| A13342 | 30024933 | PLoS One | miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling. | 2018 | Details |
| A13345 | 30021122 | Pharmacol Res | Future trends in the treatment of non-alcoholic steatohepatitis. | 2018 | Details |
| A13346 | 30019598 | Antioxid Redox Signal | Does Nox2 Overactivate in Children with Nonalcoholic Fatty Liver Disease? | 2018 | Details |
| A13347 | 30019340 | Hepatology | Nonheavy Drinking and Worsening of Noninvasive Fibrosis Markers in Nonalcoholic Fatty Liver Disease: A Cohort Study. | 2018 | Details |
| A13349 | 30019089 | Eur J Nutr | Association between dietary total antioxidant capacity and hepatocellular ballooning in nonalcoholic steatohepatitis: a cross-sectional study. | 2018 | Details |
| A13356 | 30016988 | Lipids Health Dis | Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress. | 2018 | Details |
| A13357 | 30016799 | Dig Dis | The Pattern of Elevated Liver Function Tests in Nonalcoholic Fatty Liver Disease Predicts Fibrosis Stage and Metabolic-Associated Comorbidities. | 2018 | Details |
| A13365 | 30014517 | Hepatology | ADAPT: An Algorithm Incorporating PRO-C3 Accurately Identifies Patients With NAFLD and Advanced Fibrosis. | 2019 | Details |
| A13369 | 30013758 | Middle East J Dig Dis | The Association between Angiotensin II Type 1 Receptor Gene A1166C Polymorphism and Non-alcoholic Fatty Liver Disease and Its Severity. | 2018 | Details |
| A13370 | 30013757 | Middle East J Dig Dis | Correlation between Serum Ferritin Level and Histopathological Disease Severity in Non-alcoholic Fatty Liver Disease. | 2018 | Details |
| A13373 | 30012432 | Clin Gastroenterol Hepatol | Obesity and Weight Gain Are Associated With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13376 | 30011790 | Int J Mol Sci | New Aspects of Lipotoxicity in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13381 | 30009570 | Physiol Rep | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | 2018 | Details |
| A13383 | 30008738 | PPAR Res | Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice. | 2018 | Details |
| A13385 | 30006517 | Sci Rep | Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers. | 2018 | Details |
| A13389 | 30005700 | Clin Epigenetics | Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways. | 2018 | Details |
| A13391 | 30002817 | F1000Res | Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts. | 2018 | Details |
| A13407 | 29992593 | Clin Endocrinol (Oxf) | Liver biochemical abnormalities in Turner syndrome: A comprehensive characterization of an adult population. | 2018 | Details |
| A13410 | 29991976 | Oxid Med Cell Longev | Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13411 | 29991872 | World J Gastroenterol | Apoptosis and non-alcoholic fatty liver diseases. | 2018 | Details |
| A13413 | 29990551 | Biochim Biophys Acta Mol Basis Dis | Animal models of NAFLD from a hepatologist's point of view. | 2018 | Details |
| A13414 | 29990488 | Gastroenterology | Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13416 | 29989845 | Metab Syndr Relat Disord | Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome. | 2018 | Details |
| A13436 | 29974624 | Hepatol Res | Accuracy of non-invasive scoring systems for diagnosing non-alcoholic steatohepatitis-related fibrosis: Multicenter validation study. | 2018 | Details |
| A13442 | 29971772 | J Pathol | Geranylgeranyl diphosphate synthase (GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat diet conditions. | 2018 | Details |
| A13447 | 29969922 | Expert Opin Drug Metab Toxicol | Personalized therapy when tackling nonalcoholic fatty liver disease: a focus on sex, genes, and drugs. | 2018 | Details |
| A13449 | 29968484 | J Int Med Res | Chronic heart failure in patients with nonalcoholic fatty liver disease: prevalence, clinical features, and relevance. | 2018 | Details |
| A13457 | 29963467 | Euroasian J Hepatogastroenterol | Nonalcoholic Fatty Liver Disease: Identifying the Disease Burden in Sri Lanka. | 2018 | Details |
| A13463 | 29959534 | Med Mol Morphol | Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes. | 2018 | Details |
| A13464 | 29959418 | Lab Invest | Characterization of a murine nonalcoholic steatohepatitis model induced by high fat high calorie diet plus fructose and glucose in drinking water. | 2018 | Details |
| A13465 | 29959134 | Drug Metab Dispos | Glycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-Inflammation. | 2018 | Details |
| A13466 | 29958960 | J Ethnopharmacol | The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice. | 2018 | Details |
| A13469 | 29956688 | Saudi J Gastroenterol | Nonalcoholic fatty liver disease burden - Saudi Arabia and United Arab Emirates, 2017-2030. | 2018 | Details |
| A13470 | 29956213 | Adv Exp Med Biol | Current Prevention and Treatment Options for NAFLD. | 2018 | Details |
| A13478 | 29956205 | Adv Exp Med Biol | Chemokines and Chemokine Receptors in the Development of NAFLD. | 2018 | Details |
| A13480 | 29956203 | Adv Exp Med Biol | Epidemiology and Etiologic Associations of Non-alcoholic Fatty Liver Disease and Associated HCC. | 2018 | Details |
| A13483 | 29955245 | Oxid Med Cell Longev | Hypoxic Signaling and Cholesterol Lipotoxicity in Fatty Liver Disease Progression. | 2018 | Details |
| A13487 | 29953740 | Basic Clin Pharmacol Toxicol | Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A13491 | 29951367 | J Clin Transl Hepatol | Noninvasive Quantitative Detection Methods of Liver Fat Content in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13492 | 29951362 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease: A Review of Anti-diabetic Pharmacologic Therapies. | 2018 | Details |
| A13493 | 29950116 | Expert Opin Investig Drugs | MSDC-0602K, a metabolic modulator directed at the core pathology of non-alcoholic steatohepatitis. | 2018 | Details |
| A13496 | 29948305 | J Gastroenterol | Increase in the skeletal muscle mass to body fat mass ratio predicts the decline in transaminase in patients with nonalcoholic fatty liver disease. | 2018 | Details |
| A13498 | 29947322 | Br J Nutr | Improvements in clinical characteristics of patients with non-alcoholic fatty liver disease, after an intervention based on the Mediterranean lifestyle: a randomised controlled clinical trial. | 2018 | Details |
| A13503 | 29946426 | F1000Res | Recent advances in understanding and managing non-alcoholic fatty liver disease. | 2018 | Details |
| A13504 | 29945982 | J Endocrinol | INT-767 prevents NASH and promotes visceral fat brown adipogenesis and mitochondrial function. | 2018 | Details |