Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A21259 | 25450719 | J Hepatol | Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine. | 2014 | Details |
| A21262 | 25450583 | Arch Med Res | Oral coenzyme Q10 supplementation in patients with nonalcoholic fatty liver disease: effects on serum vaspin, chemerin, pentraxin 3, insulin resistance and oxidative stress. | 2014 | Details |
| A21269 | 25445398 | J Hepatol | TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess. | 2014 | Details |
| A21283 | 27356367 | Bull Acad Natl Med | [Metabolic syndrome, non alcoholic hepatic steatopathy and hepatocellular carcinoma: so dangerous liaisons]. | 2014 | Details |
| A21287 | 25433106 | Nutr Hosp | Vitamin D levels and bone turnover markers are not related to non-alcoholic fatty liver disease in severely obese patients. | 2014 | Details |
| A21290 | 25429984 | Hepatol Res | Serum alanine aminotransferase predicts the histological course of non-alcoholic steatohepatitis in Japanese patients. | 2014 | Details |
| A21293 | 25429318 | World J Hepatol | Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease. | 2014 | Details |
| A21300 | 25422863 | Biochem J | Steatosis inhibits liver cell store-operated Ca²⁺ entry and reduces ER Ca²⁺ through a protein kinase C-dependent mechanism. | 2015 | Details |
| A21308 | 25415231 | Horm Metab Res | Leptin improves fatty liver independently of insulin sensitization and appetite suppression in hepatocyte-specific Pten-deficient mice with insulin hypersensitivity. | 2014 | Details |
| A21313 | 25413107 | Liver Int | Effect of enforced physical inactivity induced by 60-day of bed rest on hepatic markers of NAFLD in healthy normal-weight women. | 2015 | Details |
| A21323 | 25405502 | J Clin Endocrinol Metab | Liver fat content and hepatic insulin sensitivity in overweight patients with type 1 diabetes. | 2014 | Details |
| A21328 | 25402369 | Hormones (Athens) | Non-alcoholic fatty liver disease in women with polycystic ovary syndrome: assessment of non-invasive indices predicting hepatic steatosis and fibrosis. | 2014 | Details |
| A21329 | 25401691 | Nat Med | The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. | 2014 | Details |
| A21332 | 25400437 | World J Gastroenterol | Liver transplantation and non-alcoholic fatty liver disease. | 2014 | Details |
| A21334 | 25399407 | Ital J Pediatr | Chemerin as a novel non-invasive serum marker of intrahepatic lipid content in obese children. | 2014 | Details |
| A21340 | 25390016 | Horm Mol Biol Clin Investig | The pathophysiology of abdominal adipose tissue depots in health and disease. | 2014 | Details |
| A21344 | 25386164 | Front Endocrinol (Lausanne) | Bariatric surgery and non-alcoholic Fatty liver disease: current and potential future treatments. | 2014 | Details |
| A21346 | 25386071 | World J Gastroenterol | Insulin resistance and liver steatosis in chronic hepatitis C infection genotype 3. | 2014 | Details |
| A21347 | 25386056 | World J Gastroenterol | MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease. | 2014 | Details |
| A21352 | 25382334 | Chin Med J (Engl) | Expression and significance of fat mass and obesity associated gene and forkhead transcription factor O1 in non-alcoholic fatty liver disease. | 2014 | Details |
| A21357 | 25380394 | Eur J Gastroenterol Hepatol | A systematic review of the prevalence of mildly abnormal liver function tests and associated health outcomes. | 2015 | Details |
| A21359 | 25378958 | Hepat Med | Surgical treatment of nonalcoholic fatty liver disease in severely obese patients. | 2014 | Details |
| A21365 | 25371775 | Oxid Med Cell Longev | Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective. | 2014 | Details |
| A21373 | 25367327 | Food Funct | Effects of Callistephus chinensis flower polyphones on improving metabolic disorders in high-fat diet-induced mice. | 2014 | Details |
| A21379 | 25359230 | J Nutrigenet Nutrigenomics | The single nucleotide polymorphism rs499765 is associated with fibroblast growth factor 21 and nonalcoholic fatty liver disease in a Chinese population with normal glucose tolerance. | 2014 | Details |
| A21382 | 29764046 | Per Med | Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities? | 2014 | Details |
| A21386 | 25356033 | World J Gastroenterol | ADV36 adipogenic adenovirus in human liver disease. | 2014 | Details |
| A21395 | 25351290 | Liver Int | The UCP2 -866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis. | 2014 | Details |
| A21399 | 25349437 | Proc Natl Acad Sci U S A | DLK1/PREF1 regulates nutrient metabolism and protects from steatosis. | 2014 | Details |
| A21409 | 25343462 | PLoS One | Association between serum irisin levels and non-alcoholic fatty liver disease in health screen examinees. | 2014 | Details |
| A21410 | 25341597 | Turk J Pediatr | Leptin-to-adiponectin ratio in obese adolescents with nonalcoholic fatty liver disease. | 2016 | Details |
| A21413 | 25339808 | World J Gastroenterol | Non-alcoholic fatty liver disease: what has changed in the treatment since the beginning? | 2014 | Details |
| A21416 | 25339805 | World J Gastroenterol | Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome. | 2014 | Details |
| A21417 | 25336983 | J Inflamm Res | β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model. | 2014 | Details |
| A21418 | 25333896 | Mol Med Rep | Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats. | 2014 | Details |
| A21422 | 25331487 | Ann Gastroenterol | The hepatoprotective and hypolipidemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot study. | 2014 | Details |
| A21425 | 25328713 | Int J Hepatol | Fructose induced endotoxemia in pediatric nonalcoholic Fatty liver disease. | 2014 | Details |
| A21431 | 25324136 | Horm Res Paediatr | Non-alcoholic fatty liver and metabolic syndrome in children: a vicious circle. | 2014 | Details |
| A21432 | 25320541 | World J Gastroenterol | Apolipoprotein C3 (-455T>C) polymorphism confers susceptibility to nonalcoholic fatty liver disease in the Southern Han Chinese population. | 2014 | Details |
| A21440 | 25317811 | Eur Rev Med Pharmacol Sci | Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). | 2014 | Details |
| A21443 | 25313081 | Proc Natl Acad Sci U S A | Obesity accelerates epigenetic aging of human liver. | 2014 | Details |
| A21445 | 25312648 | Mol Cell Biol | Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis. | 2014 | Details |
| A21448 | 25311381 | Clin Gastroenterol Hepatol | Severity of nonalcoholic fatty liver disease and progression to cirrhosis are associated with atherogenic lipoprotein profile. | 2014 | Details |
| A21451 | 25310357 | Mol Med Rep | Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice. | 2014 | Details |
| A21455 | 25309067 | World J Gastroenterol | Nonalcoholic fatty liver disease and vascular disease: state-of-the-art. | 2014 | Details |
| A21457 | 25307311 | Mini Rev Med Chem | Long chain omega-3 polyunsaturated fatty acids in pediatric metabolic syndrome. | 2014 | Details |
| A21462 | 25303488 | J Clin Endocrinol Metab | High Prevalence of Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus and Normal Plasma Aminotransferase Levels. | 2014 | Details |
| A21468 | 25298375 | Eur J Endocrinol | External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals. | 2014 | Details |
| A21470 | 25297827 | Hepatol Res | Human placental extract treatment for non-alcoholic steatohepatitis non-responsive to lifestyle intervention: A pilot study. | 2014 | Details |
| A21473 | 25296075 | Arq Gastroenterol | Age and gender may influence the results of Roux-en-Y gastric bypass? Metabolic syndrome parameters. | 2015 | Details |
| A21479 | 25292174 | Obesity (Silver Spring) | Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression. | 2014 | Details |
| A21483 | 25289058 | Exp Ther Med | Heparin modulation on hepatic nitric oxide synthase in experimental steatohepatitis. | 2014 | Details |
| A21487 | 25282656 | J Nutr Biochem | Protein carbonylation associated to high-fat, high-sucrose diet and its metabolic effects. | 2014 | Details |
| A21489 | 25281863 | J Hepatol | Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways. | 2014 | Details |
| A21492 | 25281760 | J Lipid Res | Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance. | 2014 | Details |
| A21493 | 25281430 | Diabetes | WISP1 is a novel adipokine linked to inflammation in obesity. | 2014 | Details |
| A21494 | 25278691 | World J Gastroenterol | Non-alcoholic fatty liver disease: what the clinician needs to know. | 2014 | Details |
| A21495 | 25278690 | World J Gastroenterol | Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors. | 2014 | Details |
| A21500 | 25271296 | J Lipid Res | A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice. | 2014 | Details |
| A21504 | 25268946 | PLoS One | Carotid intima-media thickness is predicted by combined eotaxin levels and severity of hepatic steatosis at ultrasonography in obese patients with Nonalcoholic Fatty Liver Disease. | 2014 | Details |
| A21507 | 25267958 | J Gastrointestin Liver Dis | What non-alcoholic fatty liver disease has got to do with obstructive sleep apnoea syndrome and viceversa? | 2014 | Details |
| A21509 | 25267215 | Aliment Pharmacol Ther | Performance and limitations of steatosis biomarkers in patients with nonalcoholic fatty liver disease. | 2014 | Details |
| A21511 | 25266069 | J Diabetes | Alanine transferase: An independent indicator of adiposity related comorbidity risk in youth. | 2014 | Details |
| A21526 | 25253361 | Saudi J Gastroenterol | The effect of bariatric surgeries on nonalcoholic fatty liver disease. | 2015 | Details |
| A21528 | 25252208 | Acta Cir Bras | Duodenal jejunal bypass attenuates non-alcoholic fatty liver disease in western diet-obese rats. | 2014 | Details |
| A21536 | 25245380 | Curr Med Chem | Association between polycystic ovary syndrome and metabolic syndrome. | 2014 | Details |
| A21541 | 25242225 | Cell Metab | Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes. | 2014 | Details |
| A21543 | 25241608 | J Clin Res Pediatr Endocrinol | Thyroid function in obese children with non-alcoholic fatty liver disease. | 2014 | Details |
| A21552 | 25233612 | Adv Clin Chem | Metabolic syndrome in pediatrics. | 2014 | Details |
| A21556 | 25232450 | World J Hepatol | Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease. | 2014 | Details |
| A21560 | 25231693 | Endocr J | Circulating progranulin level is associated with visceral fat and elevated liver enzymes: significance of serum progranulin as a useful marker for liver dysfunction. | 2014 | Details |
| A21569 | 25220580 | Sleep Med Rev | Impact of obstructive sleep apnea treatment by continuous positive airway pressure on cardiometabolic biomarkers: a systematic review from sham CPAP randomized controlled trials. | 2014 | Details |
| A21571 | 25219574 | Liver Int | Characteristics of hepatic fatty acid compositions in patients with nonalcoholic steatohepatitis. | 2014 | Details |
| A21579 | 25215659 | Nutrients | Obesity as an emerging risk factor for iron deficiency. | 2014 | Details |
| A21585 | 25206279 | World J Gastroenterol | Osthol attenuates hepatic steatosis via decreased triglyceride synthesis not by insulin resistance. | 2014 | Details |
| A21590 | 25203315 | Hepatology | ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis. | 2015 | Details |
| A21592 | 25200997 | J Endocrinol Invest | Evaluation of serum xenin and ghrelin levels and their relationship with nonalcoholic fatty liver disease and insulin resistance in obese adolescents. | 2014 | Details |
| A21595 | 25195642 | Nutrients | Epigenetic mechanisms underlying the link between non-alcoholic fatty liver diseases and nutrition. | 2014 | Details |
| A21596 | 25195551 | J Hepatol | Relationship of vitamin D with insulin resistance and disease severity in non-alcoholic steatohepatitis. | 2014 | Details |
| A21602 | 25194181 | Best Pract Res Clin Gastroenterol | Non-alcoholic fatty liver disease, obesity and the metabolic syndrome. | 2014 | Details |
| A21607 | 25191732 | Probl Radiac Med Radiobiol | Clinical importance of the nonalcoholic fatty liver disease: a review. | 2013 | Details |
| A21621 | 25180874 | Zhonghua Gan Zang Bing Za Zhi | [Association between APOC3 promoter region polymorphisms and non-alcoholic fatty liver disease]. | 2014 | Details |
| A21622 | 25180626 | Mol Med | Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-induced simple steatosis. | 2014 | Details |
| A21626 | 30736212 | Expert Rev Endocrinol Metab | Non-alcoholic fatty liver disease in patients with diabetes mellitus. | 2014 | Details |
| A21631 | 25168159 | Med Sci Monit | Deterioration of heart rate recovery index in patients with non-alcoholic fatty liver disease (NAFLD). | 2014 | Details |
| A21635 | 25164277 | Expert Opin Investig Drugs | GFT505 for the treatment of nonalcoholic steatohepatitis and type 2 diabetes. | 2014 | Details |
| A21640 | 25163357 | Hepatol Res | Lower levels of insulin-like growth factor-1 standard deviation score are associated with histological severity of non-alcoholic fatty liver disease. | 2014 | Details |
| A21642 | 25160038 | J Transl Med | Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity. | 2014 | Details |
| A21648 | 25154569 | J Nutr Biochem | Postnatal overfeeding promotes early onset and exaggeration of high-fat diet-induced nonalcoholic fatty liver disease through disordered hepatic lipid metabolism in rats. | 2014 | Details |
| A21650 | 25152980 | Ann Hepatol | Kupffer cells: increasingly significant role in nonalcoholic fatty liver disease. | 2015 | Details |
| A21653 | 25152027 | Acta Pharmacol Sin | Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice. | 2014 | Details |
| A21657 | 25145475 | Hepatology | The role of liver fat and insulin resistance as determinants of plasma aminotransferase elevation in nonalcoholic fatty liver disease. | 2014 | Details |
| A21675 | 25128743 | Biochim Biophys Acta | Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison? | 2014 | Details |
| A21681 | 25125077 | Hepatology | Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. | 2015 | Details |
| A21690 | 25117570 | Endocr Connect | Liver status in congenital, untreated, isolated GH deficiency. | 2014 | Details |
| A21693 | 25116118 | Planta Med | Ruscogenin protects against high-fat diet-induced nonalcoholic steatohepatitis in hamsters. | 2014 | Details |
| A21695 | 25112833 | J Endocrinol | Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet. | 2014 | Details |
| A21696 | 25111713 | PLoS One | Association between noninvasive fibrosis markers and cardio-vascular organ damage among adults with hepatic steatosis. | 2014 | Details |
| A21698 | 25111123 | Nutrients | Dietary fructose reduction improves markers of cardiovascular disease risk in Hispanic-American adolescents with NAFLD. | 2014 | Details |
| A21707 | 25104497 | Am J Physiol Gastrointest Liver Physiol | Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver. | 2014 | Details |