Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
Article ID | PMID | Source | Title | Publish Year | |
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A03533 | 33965728 | Biomed Pharmacother | Açaí (Euterpe oleracea Martius) supplementation improves oxidative stress biomarkers in liver tissue of dams fed a high-fat diet and increases antioxidant enzymes' gene expression in offspring. | 2021 | Details |
A03542 | 33962276 | Ecotoxicol Environ Saf | Copper exposure association with prevalence of non-alcoholic fatty liver disease and insulin resistance among US adults (NHANES 2011-2014). | 2021 | Details |
A03544 | 33961941 | J Hepatol | Glutaminolysis-induced mTORC1 activation drives non-alcoholic steatohepatitis progression. | 2021 | Details |
A03549 | 33961302 | Hepatology | The Emerging Role of B Cells in the Pathogenesis of NAFLD. | 2021 | Details |
A03558 | 33955510 | Mol Med Rep | Parthenolide plays a protective role in the liver of mice with metabolic dysfunction‑associated fatty liver disease through the activation of the HIPPO pathway. | 2021 | Details |
A03559 | 33953864 | Iran J Basic Med Sci | Gallic acid treats dust-induced NAFLD in rats by improving the liver's anti-oxidant capacity and inhibiting ROS/NFκβ/TNFα inflammatory pathway. | 2021 | Details |
A03562 | 33953586 | Diabetes Metab Syndr Obes | Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
A03564 | 33952843 | Nihon Yakurigaku Zasshi | [The roles of gap junctional intercellular communication in non-alcoholic steatohepatitis (NASH) and liver fibrosis]. | 2021 | Details |
A03572 | 33948987 | FASEB J | Porphyran-derived oligosaccharides alleviate NAFLD and related cecal microbiota dysbiosis in mice. | 2021 | Details |
A03578 | 33947572 | Mater Sci Eng C Mater Biol Appl | Nano-encapsulation of hydroxytyrosol into formulated nanogels improves therapeutic effects against hepatic steatosis: An in vitro study. | 2021 | Details |
A03595 | 33938212 | Environ Sci Technol | Nonalcoholic Fatty Liver Disease Development in Zebrafish upon Exposure to Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate, a Novel Brominated Flame Retardant. | 2021 | Details |
A03609 | 33932956 | J Physiol | NAD+ and NAFLD - caution, causality and careful optimism. | 2021 | Details |
A03632 | 33924115 | Int J Mol Sci | Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice. | 2021 | Details |
A03634 | 33923656 | Molecules | Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis. | 2021 | Details |
A03635 | 33923525 | Nutrients | The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights. | 2021 | Details |
A03637 | 33923295 | Int J Mol Sci | Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk. | 2021 | Details |
A03643 | 33922045 | Molecules | Protective Effect of Cudrania tricuspidata Extract against High-Fat Diet Induced Nonalcoholic Fatty Liver Disease through Nrf-2/HO-1 Pathway. | 2021 | Details |
A03650 | 33920670 | Int J Mol Sci | Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCC. | 2021 | Details |
A03652 | 33919190 | Antioxidants (Basel) | The Impact of H2S on Obesity-Associated Metabolic Disturbances. | 2021 | Details |
A03653 | 33918878 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease: Focus on New Biomarkers and Lifestyle Interventions. | 2021 | Details |
A03660 | 33917360 | Antioxidants (Basel) | Lingonberry Improves Non-Alcoholic Fatty Liver Disease by Reducing Hepatic Lipid Accumulation, Oxidative Stress and Inflammatory Response. | 2021 | Details |
A03663 | 33916843 | Antioxidants (Basel) | Cisd2 Protects the Liver from Oxidative Stress and Ameliorates Western Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03671 | 33912056 | Front Pharmacol | P- Hydroxybenzyl Alcohol Alleviates Oxidative Stress in a Nonalcoholic Fatty Liver Disease Larval Zebrafish Model and a BRL-3A Hepatocyte Via the Nrf2 Pathway. | 2021 | Details |
A03688 | 33901779 | Ecotoxicol Environ Saf | Dysregulation of autophagy acts as a pathogenic mechanism of non-alcoholic fatty liver disease (NAFLD) induced by common environmental pollutants. | 2021 | Details |
A03693 | 33900847 | Am J Physiol Endocrinol Metab | High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling. | 2021 | Details |
A03702 | 33898958 | JHEP Rep | Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. | 2021 | Details |
A03725 | 33891332 | FASEB J | Silencing of STE20-type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet-induced nonalcoholic fatty liver disease. | 2021 | Details |
A03752 | 33878116 | PLoS One | Leaf powder supplementation of Senna alexandrina ameliorates oxidative stress, inflammation, and hepatic steatosis in high-fat diet-fed obese rats. | 2021 | Details |
A03757 | 33873073 | J Pharm Biomed Anal | Investigation of the therapeutic effect of Yinchen Wuling Powder on CCl4-induced hepatic fibrosis in rats by 1H NMR and MS-based metabolomics analysis. | 2021 | Details |
A03758 | 33872860 | Mol Metab | Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload. | 2021 | Details |
A03788 | 33862553 | Int Immunopharmacol | Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis. | 2021 | Details |
A03804 | 33860188 | ACS Pharmacol Transl Sci | Pyruvate Dehydrogenase as a Therapeutic Target for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03820 | 33857511 | Int J Biol Macromol | Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease and colonic tissue damage in high-fat diet fed rats. | 2021 | Details |
A03906 | 33824122 | Pak J Pharm Sci | Antioxidant characteristics and hepatoprotective effects of a formula derived from Maydis stigma, Nelumbo nucifera and Taraxacum officinale against carbon tetrachloride-induced hepatic damage in rats. | 2020 | Details |
A03910 | 33822497 | Int J Med Mushrooms | Bioactive Components and Possible Activities of Medicinal Mushrooms in Alleviating the Pathogenesis of Nonalcoholic Fatty Liver Disease (Review). | 2021 | Details |
A03912 | 33822104 | J Pharm Pharmacol | Eugenol modulates insulin sensitivity by upregulating insulin receptor substrate-2 in non-alcoholic fatty liver disease in rats. | 2021 | Details |
A03918 | 33818349 | Nutr Res Rev | Effects of betaine on non-alcoholic liver disease. | 2021 | Details |
A03925 | 33815675 | World J Hepatol | Papaya improves non-alcoholic fatty liver disease in obese rats by attenuating oxidative stress, inflammation and lipogenic gene expression. | 2021 | Details |
A03926 | 33815655 | Oxid Med Cell Longev | Effect of Different Exercise Intensities on Hepatocyte Apoptosis in HFD-Induced NAFLD in Rats: The Possible Role of Endoplasmic Reticulum Stress through the Regulation of the IRE1/JNK and eIF2α/CHOP Signal Pathways. | 2021 | Details |
A03930 | 33813878 | Am J Physiol Endocrinol Metab | Enoyl coenzyme A hydratase 1 alleviates nonalcoholic steatohepatitis in mice by suppressing hepatic ferroptosis. | 2021 | Details |
A03945 | 33810882 | Clin Investig Arterioscler | Alleviation of non-alcoholic fatty liver disease by Huazhi Fugan Granules is associated with suppression of TLR4/NF-κB signaling pathway. | 2021 | Details |
A03947 | 33810566 | Int J Mol Sci | Hepatic Senescence Accompanies the Development of NAFLD in Non-Aged Mice Independently of Obesity. | 2021 | Details |
A03955 | 33808635 | Nutrients | Role of HO-1 against Saturated Fatty Acid-Induced Oxidative Stress in Hepatocytes. | 2021 | Details |
A03972 | 33805795 | Nutrients | The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials. | 2021 | Details |
A03999 | 33794784 | BMC Gastroenterol | A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease. | 2021 | Details |
A04001 | 33794740 | Adipocyte | Swertiamarin supplementation prevents obesity-related chronic inflammation and insulin resistance in mice fed a high-fat diet. | 2021 | Details |
A04016 | 33788377 | Liver Int | Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis. | 2021 | Details |
A04020 | 33787249 | J Agric Food Chem | Malvidin-3-O-Glucoside from Blueberry Ameliorates Nonalcoholic Fatty Liver Disease by Regulating Transcription Factor EB-Mediated Lysosomal Function and Activating the Nrf2/ARE Signaling Pathway. | 2021 | Details |
A04025 | 33785339 | Life Sci | A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH. | 2021 | Details |
A04028 | 33785007 | BMC Complement Med Ther | Hepatoprotective effect of silymarin on fructose induced nonalcoholic fatty liver disease in male albino wistar rats. | 2021 | Details |
A04030 | 33783746 | Adv Exp Med Biol | Prevention of NAFLD/NASH by Astaxanthin and β-Cryptoxanthin. | 2021 | Details |
A04031 | 33783745 | Adv Exp Med Biol | Molecular Mechanisms of Nonalcoholic Fatty Liver Disease (NAFLD)/Nonalcoholic Steatohepatitis (NASH). | 2021 | Details |
A04056 | 33773953 | Redox Biol | Impact of vitamin E on redox biomarkers in non-alcoholic fatty liver disease. | 2021 | Details |
A04098 | 33761609 | Biomed Pharmacother | Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis. | 2021 | Details |
A04128 | 33746742 | Front Pharmacol | Liraglutide Alleviates Hepatic Steatosis and Liver Injury in T2MD Rats via a GLP-1R Dependent AMPK Pathway. | 2021 | Details |
A04157 | 33736456 | Antioxid Redox Signal | Sex Differences in Nonalcoholic Fatty Liver Disease: Estrogen Influence on the Liver-Adipose Tissue Crosstalk. | 2021 | Details |
A04171 | 33728991 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial DNA enables AIM2 inflammasome activation and hepatocyte pyroptosis in nonalcoholic fatty liver disease. | 2021 | Details |
A04174 | 33728021 | Oxid Med Cell Longev | Plant-Based Foods and Their Bioactive Compounds on Fatty Liver Disease: Effects, Mechanisms, and Clinical Application. | 2021 | Details |
A04175 | 33727836 | Diabetes Metab Syndr Obes | Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice. | 2021 | Details |
A04181 | 33724516 | Hepatology | Steatotic Hepatocytes Release Mature VLDL Through Methionine and Tyrosine Metabolism in a Keap1-Nrf2-Dependent Manner. | 2021 | Details |
A04200 | 33718398 | Front Med (Lausanne) | Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated Mini Review. | 2021 | Details |
A04214 | 33711421 | J Nutr Biochem | Dietary cocoa ameliorates non-alcoholic fatty liver disease and increases markers of antioxidant response and mitochondrial biogenesis in high fat-fed mice. | 2021 | Details |
A04256 | 33687168 | Int J Fertil Steril | Effect of Low-Intensity Endurance Training and High-Intensity Interval Training on Sperm Quality in Male Rats with Fatty Liver. | 2021 | Details |
A04266 | 33684693 | Biomed Pharmacother | Exploring the mechanism of PingTang No.5 capsule on nonalcoholic fatty liver disease through network pharmacology and experimental validation. | 2021 | Details |
A04275 | 33680282 | Oxid Med Cell Longev | Hepatoprotection of Lycii Fructus Polysaccharide against Oxidative Stress in Hepatocytes and Larval Zebrafish. | 2021 | Details |
A04285 | 33678036 | Hum Exp Toxicol | Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways. | 2021 | Details |
A04302 | 33671926 | Int J Mol Sci | Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact. | 2021 | Details |
A04309 | 33671262 | Nutrients | A Novel Nutraceuticals Mixture Improves Liver Steatosis by Preventing Oxidative Stress and Mitochondrial Dysfunction in a NAFLD Model. | 2021 | Details |
A04370 | 33643422 | Evid Based Complement Alternat Med | Gegen Qinlian Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats via Oxidative Stress, Inflammation, and the NLRP3 Signal Axis. | 2021 | Details |
A04386 | 33639194 | Eur J Pharmacol | Research progress in use of traditional Chinese medicine monomer for treatment of non-alcoholic fatty liver disease. | 2021 | Details |
A04392 | 33637021 | Thyroid | Comparative Analysis of the Effects of Long-Term 3,5-diiodothyronine Treatment on the Murine Hepatic Proteome and Transcriptome Under Conditions of Normal Diet and High-Fat Diet. | 2021 | Details |
A04453 | 33610041 | Biochem Biophys Res Commun | Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy. | 2021 | Details |
A04454 | 33609576 | Int J Biol Macromol | Synthesis of a green bigel using cottonseed oil/cannabis oil/alginate/ferula gum for quercetin release: Synergistic effects for treating infertility in rats. | 2021 | Details |
A04469 | 33603948 | Oxid Med Cell Longev | Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. | 2021 | Details |
A04482 | 33600604 | J Gastroenterol Hepatol | Visfatin exacerbates hepatic inflammation and fibrosis in a methionine-choline-deficient diet mouse model. | 2021 | Details |
A04522 | 33588049 | Free Radic Biol Med | Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling. | 2021 | Details |
A04542 | 33584134 | J Med Biochem | The role of oxidative stress in the development of obesity and obesity-related metabolic disorders. | 2021 | Details |
A04557 | 33580500 | J Food Sci | Major royal jelly proteins prevents NAFLD by improving mitochondrial function and lipid accumulation through activating the AMPK / SIRT3 pathway in vitro. | 2021 | Details |
A04565 | 33578702 | Antioxidants (Basel) | Mechanisms of Non-Alcoholic Fatty Liver Disease in the Metabolic Syndrome. A Narrative Review. | 2021 | Details |
A04579 | 33574380 | Sci Rep | MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model. | 2021 | Details |
A04605 | 33566044 | Food Funct | Plant sterol ester of α-linolenic acid ameliorates high-fat diet-induced nonalcoholic fatty liver disease in mice: association with regulating mitochondrial dysfunction and oxidative stress via activating AMPK signaling. | 2021 | Details |
A04614 | 33562458 | Pharmaceuticals (Basel) | The Current and Potential Therapeutic Use of Metformin-The Good Old Drug. | 2021 | Details |
A04628 | 33557653 | Expert Rev Gastroenterol Hepatol | Hepatocyte and immune cell crosstalk in non-alcoholic fatty liver disease. | 2021 | Details |
A04632 | 33557031 | Life (Basel) | Adiposity in Depression or Depression in Adiposity? The Role of Immune-Inflammatory-Microbial Overlap. | 2021 | Details |
A04661 | 33548472 | J Nutr Biochem | Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferrets. | 2021 | Details |
A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
A04684 | 33542919 | Biomed Res Int | Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice. | 2021 | Details |
A04698 | 33536442 | Sci Rep | Clinical implications of renin-angiotensin system inhibitors for development and progression of non-alcoholic fatty liver disease. | 2021 | Details |
A04716 | 33530440 | J Clin Med | NAFLD and Cardiovascular Diseases: Epidemiological, Mechanistic and Therapeutic Considerations. | 2021 | Details |
A04717 | 33530432 | Antioxidants (Basel) | Role of Oxidative Stress in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Implications for Prevention and Therapy. | 2021 | Details |
A04731 | 33524747 | Chemosphere | Thiamethoxam induces nonalcoholic fatty liver disease in mice via methionine metabolism disturb via nicotinamide N-methyltransferase overexpression. | 2021 | Details |
A04745 | 33516698 | Life Sci | Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis. | 2021 | Details |
A04775 | 33510844 | Oxid Med Cell Longev | Phloroglucinol Strengthens the Antioxidant Barrier and Reduces Oxidative/Nitrosative Stress in Nonalcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
A04784 | 33505944 | Can J Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases: The Heart of the Matter. | 2021 | Details |
A04792 | 33505147 | World J Gastroenterol | Experimental models of metabolic and alcoholic fatty liver disease. | 2021 | Details |
A04817 | 33495844 | Mol Med Rep | Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model. | 2021 | Details |
A04820 | 33494295 | Cells | Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways. | 2021 | Details |
A04822 | 33493657 | Pharmacol Res | Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects. | 2021 | Details |
A04930 | 33445755 | Antioxidants (Basel) | Targeting Autophagy to Counteract Obesity-Associated Oxidative Stress. | 2021 | Details |
A04934 | 33444725 | J Ethnopharmacol | Anti-NAFLD effect of defatted walnut powder extract in high fat diet-induced C57BL/6 mice by modulating the gut microbiota. | 2021 | Details |