Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A14774 | 29244873 | PLoS One | Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid. | 2017 | Details |
| A14775 | 29243418 | Zhongguo Zhong Yao Za Zhi | [Research progress of pharmacokinetics and pharmacodynamics of total glucosides of peony in hepatoprotective effects]. | 2017 | Details |
| A14783 | 29234937 | Pathologe | [Lysosomal acid lipase deficiency (LAL-D) : Diagnostic and therapeutic options in an underdiagnosed disease]. | 2018 | Details |
| A14786 | 29234202 | J Clin Exp Hepatol | Matrix Metalloproteinases (MMPs) in Liver Diseases. | 2017 | Details |
| A14788 | 29232673 | Ann Nutr Metab | Association Between Urinary Alpha1-Microglobulin Levels and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study. | 2017 | Details |
| A14791 | 29231919 | Pol Merkur Lekarski | [Non-alcoholic liver disease - diagnosis and treatment]. | 2017 | Details |
| A14796 | 29227477 | Nat Med | The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis. | 2017 | Details |
| A14797 | 29227069 | Fukuoka Igaku Zasshi | Molecular Mechanism of Lifestyle-related Diseases : See Both the Wood and Trees! | 2016 | Details |
| A14798 | 29226116 | Can J Gastroenterol Hepatol | Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14800 | 29225775 | F1000Res | Fibromax-based nonalcoholic fatty liver disease in chronic obstructive pulmonary disease patients with obstructive sleep apnea: Methodological considerations. | 2017 | Details |
| A14803 | 29224471 | Expert Rev Gastroenterol Hepatol | Clinical relevance of liver histopathology and different histological classifications of NASH in adults. | 2017 | Details |
| A14806 | 29224042 | Eur Arch Otorhinolaryngol | Association between continuous positive airway pressure and serum aminotransferases in patients with obstructive sleep apnea. | 2017 | Details |
| A14808 | 29223443 | Clin Gastroenterol Hepatol | Response to Pioglitazone in Patients With Nonalcoholic Steatohepatitis With vs Without Type 2 Diabetes. | 2017 | Details |
| A14809 | 29223369 | J Hepatol | A critical review of endpoints for non-cirrhotic NASH therapeutic trials. | 2017 | Details |
| A14810 | 29222961 | Liver Int | Liver zonation in children with non-alcoholic fatty liver disease: Associations with dietary fructose and uric acid concentrations. | 2018 | Details |
| A14811 | 29222917 | Hepatology | Diagnostic modalities for nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and associated fibrosis. | 2018 | Details |
| A14813 | 29222911 | Hepatology | Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2018 | Details |
| A14814 | 29222767 | Obes Surg | Platelet Counts and Liver Enzymes After Gastric Bypass Surgery. | 2018 | Details |
| A14815 | 29222421 | Sci Rep | The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14817 | 29221950 | Eur J Pharmacol | DHA supplementation prevent the progression of NASH via GPR120 signaling. | 2017 | Details |
| A14821 | 29220367 | PLoS One | Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A14830 | 29215435 | Eur J Gastroenterol Hepatol | Noninvasive fibrosis markers and chronic kidney disease among adults with nonalcoholic fatty liver in USA. | 2018 | Details |
| A14833 | 29214510 | J Cell Commun Signal | Myeloid deficiency of CCN3 exacerbates liver injury in a mouse model of nonalcoholic fatty liver disease. | 2017 | Details |
| A14853 | 29203392 | J Hepatol | Role of imaging-based biomarkers in NAFLD: Recent advances in clinical application and future research directions. | 2017 | Details |
| A14854 | 29203247 | Biochem Biophys Res Commun | Co-administration of APD668, a G protein-coupled receptor 119 agonist and linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in mice fed on a high trans-fat diet. | 2017 | Details |
| A14856 | 29202557 | Korean J Intern Med | Non-alcoholic fatty liver disease and lifestyle modifications, focusing on physical activity. | 2017 | Details |
| A14857 | 29202448 | JCI Insight | CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis. | 2017 | Details |
| A14869 | 29198531 | J Pediatr | Laparoscopic Sleeve Gastrectomy Improves Nonalcoholic Fatty Liver Disease-Related Liver Damage in Adolescents by Reshaping Cellular Interactions and Hepatic Adipocytokine Production. | 2017 | Details |
| A14883 | 29193269 | J Gastroenterol Hepatol | Additive effects of PNPLA3 and TM6SF2 on the histological severity of non-alcoholic fatty liver disease. | 2018 | Details |
| A14888 | 29190166 | Expert Opin Drug Discov | Non-alcoholic fatty liver disease (NAFLD) models in drug discovery. | 2017 | Details |
| A14889 | 29189999 | J Endocrinol Invest | NAFLD/NASH in patients with type 2 diabetes and related treatment options. | 2017 | Details |
| A14892 | 29189132 | Curr Pharm Des | Polyphenols: Novel Signaling Pathways. | 2018 | Details |
| A14909 | 29177681 | J Gastroenterol | Clinical strategy of diagnosing and following patients with nonalcoholic fatty liver disease based on invasive and noninvasive methods. | 2017 | Details |
| A14910 | 29177105 | J Clin Cell Immunol | Investigating Molecular Connections of Non-alcoholic Fatty Liver Disease with Associated Pathological Conditions in West Virginia for Biomarker Analysis. | 2017 | Details |
| A14911 | 29176844 | PLoS One | Prospective comparison among transient elastography, supersonic shear imaging, and ARFI imaging for predicting fibrosis in nonalcoholic fatty liver disease. | 2017 | Details |
| A14914 | 29175651 | Atherosclerosis | Subclinical cerebrovascular disease in NAFLD without overt risk factors for atherosclerosis. | 2017 | Details |
| A14916 | 29175242 | J Hepatol | Association of non-alcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients. | 2017 | Details |
| A14935 | 29167192 | J Investig Med | Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins. | 2017 | Details |
| A14939 | 29165568 | Am J Clin Pathol | Second Harmonic Generation Reveals Subtle Fibrosis Differences in Adult and Pediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14940 | 29164820 | Liver Int | Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models. | 2017 | Details |
| A14942 | 29163785 | Oncotarget | TM5441, a plasminogen activator inhibitor-1 inhibitor, protects against high fat diet-induced non-alcoholic fatty liver disease. | 2017 | Details |
| A14944 | 29162773 | J Atheroscler Thromb | A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats. | 2017 | Details |
| A14946 | 29161258 | PLoS One | Insulin resistance and hyperandrogenism drive steatosis and fibrosis risk in young females with PCOS. | 2017 | Details |
| A14950 | 29159325 | Hepatol Commun | Role of Aramchol in steatohepatitis and fibrosis in mice. | 2017 | Details |
| A14954 | 29158157 | Clin Gastroenterol Hepatol | Nonalcoholic Fatty Liver Disease Associates With Increased Overall Mortality and Death From Cancer, Cardiovascular Disease, and Liver Disease in Women but Not Men. | 2017 | Details |
| A14956 | 29158052 | Life Sci | Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice. | 2017 | Details |
| A14958 | 29156528 | Biomed Pharmacother | Actein ameliorates hepatic steatosis and fibrosis in high fat diet-induced NAFLD by regulation of insulin and leptin resistant. | 2017 | Details |
| A14959 | 29155718 | J Vis Exp | The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury. | 2017 | Details |
| A14960 | 29155143 | Eur J Pharmacol | Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-Induced NASH (DIN) hamster model. | 2017 | Details |
| A14961 | 29154966 | J Hepatol | Determinants of fibrosis progression and regression in NASH. | 2017 | Details |
| A14962 | 29154965 | J Hepatol | Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers. | 2017 | Details |
| A14963 | 29154964 | J Hepatol | Lipotoxicity and the gut-liver axis in NASH pathogenesis. | 2017 | Details |
| A14964 | 29154469 | Pathol Int | Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features. | 2017 | Details |
| A14965 | 29152605 | Hepatol Commun | Hepatic Natural Killer T-cell and CD8+ T-cell Signatures in Mice with Nonalcoholic Steatohepatitis. | 2017 | Details |
| A14969 | 29151428 | J Clin Sleep Med | Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis: A Systematic Review and Meta-Analysis. | 2018 | Details |
| A14970 | 29151327 | Clin Mol Hepatol | Serum matrix metalloproteinase-1 level represents disease activity as opposed to fibrosis in patients with histologically proven nonalcoholic steatohepatitis. | 2017 | Details |
| A14972 | 29150621 | Sci Rep | PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress. | 2017 | Details |
| A14974 | 29150142 | J Hepatol | Association between non-alcoholic fatty liver disease and cancer incidence rate. | 2017 | Details |
| A14979 | 29145775 | Trop Doct | Factors predicting non-alcoholic steatohepatitis (NASH) and advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). | 2017 | Details |
| A14981 | 29144460 | Nature | Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. | 2017 | Details |
| A14988 | 29137912 | Metabolism | Nonalcoholic fatty liver disease increases risk of incident chronic kidney disease: A systematic review and meta-analysis. | 2017 | Details |
| A14993 | 29133343 | Diabetes Care | Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients. | 2017 | Details |
| A14998 | 29130075 | Hepatol Commun | Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14999 | 29129819 | Metabolism | Nicotinic acetylcholine receptor α7 subunit improves energy homeostasis and inhibits inflammation in nonalcoholic fatty liver disease. | 2017 | Details |
| A15001 | 29128938 | J Med Ultrason (2001) | Liver fibrosis: noninvasive assessment using supersonic shear imaging and FIB4 index in patients with non-alcoholic fatty liver disease. | 2017 | Details |
| A15002 | 29128391 | J Hepatol | Preclinical models of non-alcoholic fatty liver disease. | 2017 | Details |
| A15006 | 29128063 | Clin Liver Dis | Radiologic Imaging in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15007 | 29128062 | Clin Liver Dis | Diagnosis and Evaluation of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Noninvasive Biomarkers and Transient Elastography. | 2018 | Details |
| A15008 | 29128061 | Clin Liver Dis | The Genetics of Pediatric Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15010 | 29128059 | Clin Liver Dis | Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15018 | 29128051 | Clin Liver Dis | The Natural History of Nonalcoholic Fatty Liver Disease-An Evolving View. | 2018 | Details |
| A15019 | 29128050 | Clin Liver Dis | The Use of Liver Biopsy in Nonalcoholic Fatty Liver Disease: When to Biopsy and in Whom. | 2018 | Details |
| A15020 | 29128049 | Clin Liver Dis | Clinical and Economic Burden of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15024 | 29126863 | Surg Obes Relat Dis | Utility of transient elastography (fibroscan) and impact of bariatric surgery on nonalcoholic fatty liver disease (NAFLD) in morbidly obese patients. | 2017 | Details |
| A15032 | 29122851 | Gut | Guidelines on the management of abnormal liver blood tests. | 2017 | Details |
| A15035 | 29122694 | J Hepatol | Pharmacotherapy for NASH: Current and emerging. | 2017 | Details |
| A15038 | 29122391 | J Hepatol | Genetics and epigenetics of NAFLD and NASH: Clinical impact. | 2017 | Details |
| A15044 | 29119725 | Obes Rev | Systematic review and meta-analysis: non-invasive detection of non-alcoholic fatty liver disease related fibrosis in the obese. | 2017 | Details |
| A15047 | 29119336 | Obes Surg | Bariatric Surgery as an Efficient Treatment for Non-Alcoholic Fatty Liver Disease in a Prospective Study with 1-Year Follow-up : BariScan Study. | 2018 | Details |
| A15058 | 29115682 | Aliment Pharmacol Ther | Risk factors for biopsy-proven advanced non-alcoholic fatty liver disease in the Veterans Health Administration. | 2017 | Details |
| A15063 | 29113510 | Diab Vasc Dis Res | Interrelationship of canonical and non-canonical Wnt signalling pathways in chronic metabolic diseases. | 2017 | Details |
| A15065 | 29113028 | Hepatology | Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis. | 2018 | Details |
| A15069 | 29109528 | Sci Rep | Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) - an 11-Year Prospective Study. | 2017 | Details |
| A15074 | 29108191 | Zhonghua Gan Zang Bing Za Zhi | [An interpretation of the AASLD practice guideline on the diagnosis and management of nonalcoholic fatty liver disease in 2017]. | 2017 | Details |
| A15078 | 29107284 | Mol Metab | Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice. | 2017 | Details |
| A15081 | 29106384 | J Clin Invest | Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression. | 2017 | Details |
| A15086 | 29104128 | Clin Gastroenterol Hepatol | Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. | 2018 | Details |
| A15087 | 29104004 | Surg Obes Relat Dis | Nonalcoholic fatty liver disease in patients with different baseline glucose status undergoing bariatric surgery: analysis of intraoperative liver biopsies and literature review. | 2017 | Details |
| A15090 | 29101772 | Rom J Intern Med | Liver disease symptoms in non-alcoholic fatty liver disease and small intestinal bacterial overgrowth. | 2018 | Details |
| A15094 | 29099463 | J Clin Gastroenterol | Associations of Insulin Resistance and Glycemia With Liver Enzymes in Hispanic/Latino Youths: Results From the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth). | 2019 | Details |
| A15096 | 29098121 | Curr Pathobiol Rep | Using zebrafish to model liver diseases-Where do we stand? | 2017 | Details |
| A15098 | 29097288 | Diabetes Res Clin Pract | Trend over time in hepatic fibrosis score in a cohort of type 2 diabetes patients. | 2017 | Details |
| A15099 | 29097281 | Biochimie | Steatosis and NASH in type 2 diabetes. | 2017 | Details |
| A15100 | 29096730 | Gene Expr | Updates on Dietary Models of Nonalcoholic Fatty Liver Disease: Current Studies and Insights. | 2017 | Details |
| A15101 | 29095942 | PLoS One | Serum high mobility group box 1 protein levels are not associated with either histological severity or treatment response in children and adults with nonalcoholic fatty liver disease. | 2017 | Details |
| A15102 | 29094442 | Diabet Med | Prevalence and severity of non-alcoholic fatty liver disease are underestimated in clinical practice: impact of a dedicated screening approach at a large university teaching hospital. | 2018 | Details |
| A15111 | 29089822 | Korean J Radiol | Impact of Liver Fibrosis and Fatty Liver on T1rho Measurements: A Prospective Study. | 2017 | Details |
| A15116 | 29086488 | J Diabetes Investig | Molecular mechanism of obesity-induced 'metabolic' tissue remodeling. | 2017 | Details |
| A15117 | 29086016 | J Gastroenterol | Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma. | 2017 | Details |
| A15118 | 29085919 | Hepatol Commun | MELD-Na score predicts incident major cardiovascular events, in patients with nonalcoholic fatty liver disease (NAFLD). | 2017 | Details |