Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A28520 | 12214335 | Rev Gastroenterol Mex | [Non-alcoholic steatohepatitis]. | 2002 | Details |
| A28524 | 12127930 | Clin Nutr | Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis. | 2002 | Details |
| A28532 | 11944631 | Semin Gastrointest Dis | Fat and the liver--a molecular overview. | 2002 | Details |
| A28535 | 11915020 | Hepatology | Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. | 2002 | Details |
| A28537 | 11907349 | J Clin Gastroenterol | Intestinal permeation and gastrointestinal disease. | 2002 | Details |
| A28539 | 11838612 | Dig Liver Dis | Liver inflammatory cells, apoptosis, regeneration and stellate cell activation in non-alcoholic steatohepatitis. | 2001 | Details |
| A28551 | 11564008 | Aliment Pharmacol Ther | Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. | 2001 | Details |
| A28566 | 10893995 | Praxis (Bern 1994) | [Non-alcoholic steato-hepatitis]. | 2000 | Details |
| A28567 | 10804323 | Diabetes Metab | Non-alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss. | 2000 | Details |
| A28573 | 10048738 | Scand J Gastroenterol | The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients. | 1999 | Details |
| A28574 | 10029293 | J Gastroenterol Hepatol | Does steatohepatitis impair liver regeneration? A study in a dietary model of non-alcoholic steatohepatitis in rats. | 1999 | Details |
| A28585 | 8052745 | Rev Invest Clin | [Non-alcoholic fatty liver: 10 years' experience at the Insituto Nacional de la Nutrición Salvador Zubirán]. | 1994 | Details |
| A28592 | 8471080 | Alcohol Alcohol | Detection of antibodies to acetaldehyde-albumin conjugates in alcoholic liver disease. | 1993 | Details |
| A28595 | 1526433 | Gastroenterol Jpn | Clinicopathologic study of alcohol-like liver disease in non-alcoholics; non-alcoholic steatohepatitis and fibrosis. | 1992 | Details |
| A28597 | 1782374 | J Gastroenterol Hepatol | Non-alcoholic steatohepatitis: impaired antipyrine metabolism and hypertriglyceridaemia may be clues to its pathogenesis. | 1992 | Details |
| A28612 | 35235346 | Sci Adv | Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors. | 2022 | Details |
| A28618 | 35226336 | J Endocrinol Invest | Potential biomarkers in the fibrosis progression of nonalcoholic steatohepatitis (NASH). | 2022 | Details |
| A28622 | 35219165 | Int Immunopharmacol | Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4+ T cells in chronic liver injury. | 2022 | Details |
| A28624 | 35217816 | Acta Pharmacol Sin | The role of REV-ERB in NASH. | 2022 | Details |
| A28625 | 35217809 | Acta Pharmacol Sin | FXR: structures, biology, and drug development for NASH and fibrosis diseases. | 2022 | Details |
| A28636 | 35212988 | Methods Mol Biol | Mouse Bone Marrow Cell Isolation and Macrophage Differentiation. | 2022 | Details |
| A28637 | 35212585 | Expert Rev Clin Immunol | Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives. | 2022 | Details |
| A28649 | 35183812 | Ecotoxicol Environ Saf | Chronic exposure to low-dose cadmium facilitated nonalcoholic steatohepatitis in mice by suppressing fatty acid desaturation. | 2022 | Details |
| A28650 | 35183762 | Nanomedicine | Platelet-neutrophil hybrid membrane-coated gelatin nanoparticles for enhanced targeting ability and intelligent release in the treatment of non-alcoholic steatohepatitis. | 2022 | Details |
| A28682 | 35137921 | Int J Mol Med | Resveratrol ameliorates nutritional steatohepatitis through the mmu‑miR‑599/PXR pathway. | 2022 | Details |
| A28690 | 35126150 | Front Pharmacol | Deciphering the Effective Constituents and Mechanisms of Portulaca oleracea L. for Treating NASH via Integrating Bioinformatics Analysis and Experimental Pharmacology. | 2022 | Details |
| A28698 | 35116066 | Evid Based Complement Alternat Med | Evaluation of the Mechanism of Modified Lingguizhugan Decoction in the Treatment of Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A28717 | 35101153 | Inflamm Regen | A novel prostaglandin I2 agonist, ONO-1301, attenuates liver inflammation and suppresses fibrosis in non-alcoholic steatohepatitis model mice. | 2022 | Details |
| A28724 | 35092721 | J Control Release | Hepatic macrophage targeted siRNA lipid nanoparticles treat non-alcoholic steatohepatitis. | 2022 | Details |
| A28730 | 35087844 | Front Med (Lausanne) | An Update in Epigenetics in Metabolic-Associated Fatty Liver Disease. | 2022 | Details |
| A28733 | 35085894 | Biochem Biophys Res Commun | Liver cyclophilin D deficiency inhibits the progression of early NASH by ameliorating steatosis and inflammation. | 2022 | Details |
| A28755 | 35058729 | J Ginseng Res | Oral administration of Jinan Red Ginseng and licorice extract mixtures ameliorates nonalcoholic steatohepatitis by modulating lipogenesis. | 2021 | Details |
| A28759 | 35052810 | Biomedicines | Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis. | 2022 | Details |
| A28795 | 34997987 | Hepatology | NOD-like receptor protein 3 activation causes spontaneous inflammation and fibrosis that mimics human NASH. | 2022 | Details |
| A28817 | 34944770 | Biomedicines | Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells. | 2021 | Details |
| A28833 | 34924279 | Drug Resist Updat | Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma? | 2021 | Details |
| A28835 | 34923550 | Curr Opin Oncol | Immunomodulation for hepatocellular carcinoma therapy: current challenges. | 2022 | Details |
| A28842 | 34919247 | Eur Rev Med Pharmacol Sci | A randomized controlled trial comparing the effects of Vitamin E, Ursodeoxycholic acid and Pentoxifylline on Egyptian non-alcoholic steatohepatitis patients. | 2021 | Details |
| A28846 | 34917911 | JHEP Rep | ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. | 2021 | Details |
| A28865 | 34890841 | Cell Mol Gastroenterol Hepatol | Sphingosine 1-Phosphate Receptor 4 Promotes Nonalcoholic Steatohepatitis by Activating NLRP3 Inflammasome. | 2021 | Details |
| A28867 | 34888761 | Drugs Aging | Non-Steroidal Anti-Inflammatory Drugs and Risk of Acute Kidney Injury and Hyperkalemia in Older Adults: A Retrospective Cohort Study and External Validation of a Clinical Risk Model. | 2021 | Details |
| A28874 | 34882936 | EMBO Rep | Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction. | 2021 | Details |
| A28906 | 34843960 | Pharmacol Res | Old wine in new bottles: Kaempferol is a promising agent for treating the trilogy of liver diseases. | 2021 | Details |
| A28928 | 34805145 | Front Cell Dev Biol | A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity. | 2021 | Details |
| A28956 | 34781165 | Redox Biol | The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30. | 2021 | Details |
| A28973 | 34757037 | J Genet Genomics | Tumor necrosis factor-α signaling in nonalcoholic steatohepatitis and targeted therapies. | 2021 | Details |
| A28983 | 34741448 | Hepatol Commun | Dissecting the Balance Between Metabolic and Oncogenic Functions of Astrocyte-Elevated Gene-1/Metadherin. | 2021 | Details |
| A29007 | 34712137 | Front Pharmacol | Micronized Palmitoylethanolamide Ameliorates Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis via Inhibiting Inflammation and Restoring Autophagy. | 2021 | Details |
| A29069 | 34624527 | Cell Mol Gastroenterol Hepatol | Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways. | 2021 | Details |
| A29086 | 34603061 | Front Pharmacol | Berberine Alleviates Non-alcoholic Steatohepatitis Through Modulating Gut Microbiota Mediated Intestinal FXR Activation. | 2021 | Details |
| A29090 | 34592216 | J Mol Biol | Pyroptosis in Steatohepatitis and Liver Diseases. | 2021 | Details |
| A29091 | 34586589 | Clin Rev Allergy Immunol | Antimitochondrial Antibodies: from Bench to Bedside. | 2021 | Details |
| A29148 | 34506952 | Cell Mol Gastroenterol Hepatol | Activated Natural Killer Cell Promotes Nonalcoholic Steatohepatitis Through Mediating JAK/STAT Pathway. | 2021 | Details |
| A29155 | 34493955 | New Microbes New Infect | Incidence, characteristics, and outcome of COVID-19 in patients on liver transplant program: a retrospective study in the north of Iran. | 2021 | Details |
| A29175 | 34470535 | Hum Exp Toxicol | Effect of curcumin on the non-alcoholic steatohepatitis via inhibiting the M1 polarization of macrophages. | 2021 | Details |
| A29211 | 34411785 | Cell Mol Gastroenterol Hepatol | SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis. | 2021 | Details |
| A29246 | 34363605 | J Physiol Biochem | HGF can reduce accumulation of inflammation and regulate glucose homeostasis in T2D mice. | 2021 | Details |
| A29247 | 34360581 | Int J Mol Sci | The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (H2S) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia. | 2021 | Details |
| A29255 | 34352389 | Biochim Biophys Acta Mol Cell Biol Lipids | Proresolving lipid mediators and liver disease. | 2021 | Details |
| A29280 | 34305946 | Front Immunol | The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation. | 2021 | Details |
| A29303 | 34278710 | Aging Cell | Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. | 2021 | Details |
| A29316 | 34262459 | Front Pharmacol | Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway. | 2021 | Details |
| A29319 | 34260795 | Hepatol Res | Efficacy and safety of apararenone (MT-3995) in patients with nonalcoholic steatohepatitis: A randomized controlled study. | 2021 | Details |
| A29367 | 34176099 | Drug Deliv Transl Res | Targeting the extracellular matrix for immunomodulation: applications in drug delivery and cell therapies. | 2021 | Details |
| A29410 | 34117031 | Cancer Res | Multiple Roles of IL6 in Hepatic Injury, Steatosis, and Senescence Aggregate to Suppress Tumorigenesis. | 2021 | Details |
| A29423 | 34093242 | Front Physiol | Nobiletin Alleviates Non-alcoholic Steatohepatitis in MCD-Induced Mice by Regulating Macrophage Polarization. | 2021 | Details |
| A29454 | 34041450 | iScience | Myeloid Nrf2 deficiency aggravates non-alcoholic steatohepatitis progression by regulating YAP-mediated NLRP3 inflammasome signaling. | 2021 | Details |
| A29576 | 33848669 | Clin Res Hepatol Gastroenterol | Neutrophil extracellular traps induced by pro-inflammatory cytokines enhance procoagulant activity in NASH patients. | 2021 | Details |
| A29606 | 33808404 | Biomedicines | Dulaglutide Alone and in Combination with Empagliflozin Attenuate Inflammatory Pathways and Microbiome Dysbiosis in a Non-Diabetic Mouse Model of NASH. | 2021 | Details |
| A29616 | 33796224 | Oncotarget | Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models. | 2021 | Details |
| A29623 | 33787460 | J Recept Signal Transduct Res | SIRT1/NFκB pathway mediates anti-inflammatory and anti-apoptotic effects of rosmarinic acid on in a mouse model of nonalcoholic steatohepatitis (NASH). | 2021 | Details |
| A29741 | 33592148 | J Med Chem | Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. | 2021 | Details |
| A29742 | 33590776 | Gut Microbes | The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases. | 2022 | Details |
| A29753 | 33564498 | Cureus | A Review of Pirfenidone as an Anti-Fibrotic in Idiopathic Pulmonary Fibrosis and Its Probable Role in Other Diseases. | 2021 | Details |
| A29786 | 33521599 | iScience | Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH. | 2021 | Details |
| A29792 | 33513920 | Biomedicines | Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities. | 2021 | Details |
| A29820 | 33447518 | J Clin Transl Hepatol | A 3D Human Liver Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29933 | 33251276 | Visc Med | Emerging Pharmacological Treatment in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29963 | 33198153 | Biology (Basel) | Emerging Roles of Liver Sinusoidal Endothelial Cells in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30072 | 33022884 | J Diabetes | Integrative analysis of hepatic metabolomic and transcriptomic data reveals potential mechanism of nonalcoholic steatohepatitis in high-fat diet-fed mice. | 2020 | Details |
| A30098 | 32990984 | J Bone Miner Res | A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice. | 2020 | Details |
| A30102 | 32979923 | J Neuroinflammation | TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model. | 2020 | Details |
| A30119 | 32954509 | Ann N Y Acad Sci | Characterization of hydrogen sulfide toxicity to human corneal stromal fibroblasts. | 2020 | Details |
| A30146 | 32903542 | Front Cell Dev Biol | Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner. | 2020 | Details |
| A30156 | 32882802 | Antioxidants (Basel) | Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation. | 2020 | Details |
| A30167 | 32875282 | JHEP Rep | Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis. | 2020 | Details |
| A30204 | 32821335 | World J Hepatol | Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis. | 2020 | Details |
| A30275 | 32713066 | J Food Biochem | β-Glucan ameliorates nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice. | 2020 | Details |
| A30280 | 32705539 | J Cell Commun Signal | Et tu, CCN1…. | 2020 | Details |
| A30324 | 32645655 | J Nutr Biochem | The deficit in folate and vitamin B12 triggers liver macrovesicular steatosis and inflammation in rats with dextran sodium sulfate-induced colitis. | 2020 | Details |
| A30396 | 32508844 | Front Immunol | CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy. | 2020 | Details |
| A30407 | 32493884 | Exp Anim | Gender difference in development of steatohepatitis in p62/Sqstm1 and Nrf2 double-knockout mice. | 2020 | Details |
| A30436 | 32448510 | Biochem Biophys Res Commun | Involvement of activation of PLIN5-Sirt1 axis in protective effect of glycycoumarin on hepatic lipotoxicity. | 2020 | Details |
| A30438 | 32443737 | Cancers (Basel) | Molecular Mechanisms Regulating Obesity-Associated Hepatocellular Carcinoma. | 2020 | Details |
| A30462 | 32410268 | J Biochem Mol Toxicol | Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis. | 2020 | Details |
| A30489 | 32355675 | Hepatobiliary Surg Nutr | Probiotics VSL#3 are effective in reversing non-alcoholic steatohepatitis in a mouse model. | 2020 | Details |
| A30490 | 32355674 | Hepatobiliary Surg Nutr | Bile acid-based therapies for non-alcoholic steatohepatitis and alcoholic liver disease. | 2020 | Details |
| A30495 | 32341704 | J Med Life | Signification of Serum Alpha-Fetoprotein Levels in Cases of Compensated Cirrhosis and Hepatitis C Virus without Hepatocellular Carcinoma. | 2020 | Details |
| A30519 | 32291331 | J Lipid Res | Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease. | 2020 | Details |
| A30564 | 32205234 | Pharmacol Res | Obesity and NRF2-mediated cytoprotection: Where is the missing link? | 2020 | Details |