Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Diabetes mellitus4971 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52309 | 28811294 | Am J Physiol Endocrinol Metab | Dihydrocapsiate improved age-associated impairments in mice by increasing energy expenditure. | 2017 | Details |
| A52310 | 28811292 | Am J Physiol Endocrinol Metab | Dapagliflozin slows the progression of the renal and liver fibrosis associated with type 2 diabetes. | 2017 | Details |
| A52315 | 28759094 | J Am Osteopath Assoc | Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases? | 2017 | Details |
| A52319 | 28711626 | Gastroenterology | Influence of Metabolic Risk Factors on Risk of Hepatocellular Carcinoma and Liver-Related Death in Men With Chronic Hepatitis B: A Large Cohort Study. | 2017 | Details |
| A52321 | 28689096 | Eur J Med Chem | Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. | 2017 | Details |
| A52326 | 28549111 | Cardiovasc Res | Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. | 2017 | Details |
| A52334 | 28431322 | J Nutr Biochem | Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice. | 2017 | Details |
| A52342 | 28392997 | Kidney Res Clin Pract | Fatty liver associated with metabolic derangement in patients with chronic kidney disease: A controlled attenuation parameter study. | 2017 | Details |
| A52355 | 28232517 | J Investig Med | Impact of sustained virological response to chronic hepatitic C antiviral therapy on new onset diabetes mellitus type 2 after controlling for metabolic syndrome. | 2017 | Details |
| A52356 | 28223503 | Proc Natl Acad Sci U S A | Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. | 2017 | Details |
| A52357 | 28222147 | PLoS One | The desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact of mitochondrial redox state. | 2017 | Details |
| A52366 | 28116842 | HIV Med | Fat mass and obesity-associated gene variations are related to fatty liver disease in HIV-infected patients. | 2017 | Details |
| A52370 | 28086952 | J Med Case Rep | Glucagon-like peptide-1 analogues - an efficient therapeutic option for the severe insulin resistance of lipodystrophic syndromes: two case reports. | 2017 | Details |
| A52373 | 28052632 | Liver Int | Impact of hepatitis C virus therapy on metabolism and public health. | 2017 | Details |
| A52378 | 27919367 | J Clin Lipidol | Familial partial lipodystrophy presenting as metabolic syndrome. | 2016 | Details |
| A52380 | 27884961 | J Lipid Res | Therapeutic silencing of fat-specific protein 27 improves glycemic control in mouse models of obesity and insulin resistance. | 2016 | Details |
| A52396 | 29489091 | Cesk Fysiol | Metabolically healthy obese individuals -- mechanisms and clinical relevance. | 2016 | Details |
| A52397 | 27659144 | Trends Endocrinol Metab | Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective. | 2016 | Details |
| A52401 | 27615511 | Immunobiology | Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and healthy controls. The GEA study. | 2016 | Details |
| A52402 | 30452850 | J Med Pract Manage | Ketogenic Weight Loss: The Lowering of Insulin Levels Is the Sleeping Giant in Patient Care. | 2016 | Details |
| A52407 | 27533883 | Environ Toxicol | Exposure to an environmentally relevant mixture of organochlorine compounds and polychlorinated biphenyls Promotes hepatic steatosis in male Ob/Ob mice. | 2016 | Details |
| A52412 | 27382035 | Am J Physiol Endocrinol Metab | Targeting ceramide metabolism in obesity. | 2016 | Details |
| A52413 | 27380543 | Histopathology | Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse. | 2016 | Details |
| A52417 | 27351077 | Endocr Res | Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study. | 2016 | Details |
| A52420 | 27317329 | BMC Genet | Haplotype analysis of the HFE gene among populations of Northern Eurasia, in patients with metabolic disorders or stomach cancer, and in long-lived people. | 2016 | Details |
| A52435 | 27163748 | Int J Obes (Lond) | Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. | 2016 | Details |
| A52436 | 27138913 | Diabetologia | Neuronal human BACE1 knockin induces systemic diabetes in mice. | 2016 | Details |
| A52454 | 26976583 | Proc Natl Acad Sci U S A | Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. | 2016 | Details |
| A52458 | 26921251 | Oncotarget | Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model. | 2016 | Details |
| A52467 | 26730168 | World J Gastroenterol | Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality. | 2015 | Details |
| A52474 | 26603189 | Cell Metab | Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism. | 2015 | Details |
| A52476 | 26562264 | Endocrinology | Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male Mice. | 2015 | Details |
| A52477 | 26546347 | J Cardiovasc Magn Reson | Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance. | 2015 | Details |
| A52482 | 26476226 | Rheum Dis Clin North Am | Comorbidities in Psoriatic Arthritis. | 2015 | Details |
| A52496 | 26348073 | J Physiol Pharmacol | Emerging role of fecal microbiota therapy in the treatment of gastrointestinal and extra-gastrointestinal diseases. | 2015 | Details |
| A52503 | 26275081 | Eur J Gastroenterol Hepatol | Cardiovascular events in chronic hepatitis C: prognostic value of liver stiffness evolution. | 2015 | Details |
| A52508 | 26250749 | Cytokine Growth Factor Rev | Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease. | 2015 | Details |
| A52509 | 26244977 | PLoS One | Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice. | 2015 | Details |
| A52510 | 26209814 | Atherosclerosis | Liver fat, statin use, and incident diabetes: The Multi-Ethnic Study of Atherosclerosis. | 2015 | Details |
| A52518 | 26112408 | J Biol Chem | Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway. | 2015 | Details |
| A52542 | 25766534 | Cell Physiol Biochem | Increased oxidative stress and mitochondrial dysfunction in zucker diabetic rat liver and brain. | 2015 | Details |
| A52560 | 25603040 | Curr Opin Rheumatol | Recognizing and managing comorbidities in psoriatic arthritis. | 2015 | Details |
| A52563 | 25592279 | Mol Biosyst | Dissection of metabolic pathways in the Db/Db mouse model by integrative proteome and acetylome analysis. | 2015 | Details |
| A52573 | 25445417 | Clin Chim Acta | The role of circulating lipoprotein lipase and adiponectin on the particle size of remnant lipoproteins in patients with diabetes mellitus and metabolic syndrome. | 2014 | Details |
| A52575 | 25443347 | J Hepatol | Facts and fictions of HCV and comorbidities: steatosis, diabetes mellitus, and cardiovascular diseases. | 2014 | Details |
| A52578 | 25418362 | Mol Cell Proteomics | Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins. | 2014 | Details |
| A52584 | 25367448 | BMC Med | FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients. | 2014 | Details |
| A52611 | 24916550 | Nutr Res | Liver function parameters, cholesterol, and phospholipid α-linoleic acid are associated with adipokine levels in overweight and obese adults. | 2014 | Details |
| A52624 | 24659875 | World J Gastroenterol | Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. | 2014 | Details |
| A52625 | 24652725 | Diabetes Care | Dietary sugar and body weight: have we reached a crisis in the epidemic of obesity and diabetes?: health be damned! Pour on the sugar. | 2014 | Details |
| A52632 | 24473532 | Menopause | Resveratrol- and melatonin-abated ovariectomy and fructose diet-induced obesity and metabolic alterations in female rats. | 2014 | Details |
| A52635 | 24438728 | Prog Cardiovasc Dis | Overview of epidemiology and contribution of obesity to cardiovascular disease. | 2013 | Details |
| A52641 | 24297848 | J Physiol | Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. | 2013 | Details |
| A52645 | 24237940 | Liver Int | Non-invasive hepatic biomarkers (ELF and CK18) in people with type 2 diabetes: the Edinburgh type 2 diabetes study. | 2013 | Details |
| A52658 | 24051694 | Mod Pathol | Noncirrhotic hepatocellular carcinoma: derivation from hepatocellular adenoma? Clinicopathologic analysis. | 2013 | Details |
| A52665 | 23954796 | J Am Heart Assoc | Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction. | 2013 | Details |
| A52668 | 23886976 | Benef Microbes | Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics. | 2014 | Details |
| A52674 | 23769925 | Gene | The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight. | 2013 | Details |
| A52685 | 23551521 | J Intern Med | Ectopic lipid storage and insulin resistance: a harmful relationship. | 2013 | Details |
| A52693 | 23445230 | Expert Rev Gastroenterol Hepatol | The predictive value of steatosis in hepatitis C virus infection. | 2013 | Details |
| A52709 | 23128765 | Nestle Nutr Inst Workshop Ser | Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity. | 2012 | Details |
| A52712 | 23047931 | Endocr Pract | Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge. | 2013 | Details |
| A52714 | 23043895 | Trends Endocrinol Metab | Dissociating fatty liver and diabetes. | 2012 | Details |
| A52717 | 22925001 | Br J Pharmacol | Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans. | 2013 | Details |
| A52722 | 22829562 | Endocr Rev | Cardiometabolic aspects of the polycystic ovary syndrome. | 2012 | Details |
| A52723 | 22825472 | Cell Death Dis | Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. | 2012 | Details |
| A52724 | 22820893 | Endocrine | Fetuin-A and angiopoietins in obesity and type 2 diabetes mellitus. | 2012 | Details |
| A52742 | 22546076 | Atherosclerosis | Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. | 2012 | Details |
| A52744 | 22506114 | Biochem Res Int | Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. | 2012 | Details |
| A52749 | 22481453 | Ann Hepatol | Serum adipocyte fatty acid binding protein in liver transplant recipients and the metabolic syndrome. | 2012 | Details |
| A52751 | 22471957 | Cardiovasc Hematol Agents Med Chem | PPAR- γ agonist in treatment of diabetes: cardiovascular safety considerations. | 2012 | Details |
| A52758 | 22393439 | PLoS One | Fatty liver index predicts further metabolic deteriorations in women with previous gestational diabetes. | 2012 | Details |
| A52761 | 22350143 | J Nat Med | Puerariae flos alleviates metabolic diseases in Western diet-loaded, spontaneously obese type 2 diabetic model mice. | 2012 | Details |
| A52775 | 22180634 | J Lipid Res | Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice. | 2011 | Details |
| A52783 | 22005032 | Biochim Biophys Acta | Hypertriglyceridemia secondary to obesity and diabetes. | 2011 | Details |
| A52795 | 21818837 | Diabetes Metab Res Rev | Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat. | 2012 | Details |
| A52798 | 21756316 | Cardiovasc Diabetol | Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs. | 2011 | Details |
| A52804 | 21549160 | Regul Pept | GLP-1-derived nonapeptide GLP-1(28-36)amide inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A52805 | 21536228 | Gend Med | Relations of adiponectin to levels of metabolic parameters and sexual hormones in elderly type 2 diabetic patients. | 2011 | Details |
| A52809 | 21488080 | Hepatology | Fatty liver index and mortality: the Cremona study in the 15th year of follow-up. | 2011 | Details |
| A52810 | 21473944 | N Biotechnol | Antibodies in metabolic diseases. | 2011 | Details |
| A52813 | 21429276 | Br J Nutr | Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. | 2011 | Details |
| A52821 | 21310864 | J Nutr | Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. | 2011 | Details |
| A52826 | 21250778 | Arch Physiol Biochem | Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? | 2011 | Details |
| A52827 | 21199519 | J Gastroenterol Hepatol | Hepatic steatosis and hepatitis C: Still unhappy bedfellows? | 2011 | Details |
| A52828 | 21194577 | Am J Med | Initial combination therapy for type 2 diabetes mellitus: is it ready for prime time? | 2011 | Details |
| A52829 | 21205225 | Basic Clin Pharmacol Toxicol | Monosodium glutamate neonatal intoxication associated with obesity in adult stage is characterized by chronic inflammation and increased mRNA expression of peroxisome proliferator-activated receptors in mice. | 2011 | Details |
| A52831 | 21178610 | Curr Opin Clin Nutr Metab Care | Fatty acid regulation of hepatic lipid metabolism. | 2011 | Details |
| A52833 | 21145849 | J Hepatol | Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. | 2010 | Details |
| A52840 | 21036943 | Hum Mol Genet | Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance. | 2010 | Details |
| A52844 | 20876715 | Diabetes | Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis. | 2010 | Details |
| A52847 | 20824098 | PLoS One | Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. | 2010 | Details |
| A52856 | 20619595 | Presse Med | [Radical complications of obesity]. | 2010 | Details |
| A52858 | 20578130 | Hepatology | Hepatic steatosis in patients coinfected with human immunodeficiency virus/hepatitis C virus: a meta-analysis of the risk factors. | 2010 | Details |
| A52860 | 20544878 | Environ Mol Mutagen | The mitochondrial proteome: a dynamic functional program in tissues and disease states. | 2010 | Details |
| A52862 | 20536513 | Diabet Med | Do high ferritin levels confer lower cardiovascular risk in men with Type 2 diabetes? | 2010 | Details |
| A52874 | 20361178 | Diabetologia | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. | 2010 | Details |
| A52886 | 20021538 | J Clin Hypertens (Greenwich) | Pathogenesis and pathophysiology of the cardiometabolic syndrome. | 2009 | Details |
| A52901 | 19796990 | Curr Opin Pharmacol | The role of mitochondria in health and disease. | 2009 | Details |
| A52910 | 19689382 | Infect Disord Drug Targets | Relevance of nutritional antioxidants in metabolic syndrome, ageing and cancer: potential for therapeutic targeting. | 2009 | Details |