Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Fructose1035 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12750 | 30303744 | FASEB J | Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis. | 2018 | Details |
| A12878 | 30244972 | Cell Metab | Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma. | 2018 | Details |
| A12880 | 30244573 | J Agric Food Chem | Black Sesame Seeds Ethanol Extract Ameliorates Hepatic Lipid Accumulation, Oxidative Stress, and Insulin Resistance in Fructose-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12897 | 30235828 | Nutrients | Non-Alcoholic Fatty Liver Disease in Overweight Children: Role of Fructose Intake and Dietary Pattern. | 2018 | Details |
| A12978 | 30200408 | Nutrients | Muscle Loss in Chronic Liver Diseases: The Example of Nonalcoholic Liver Disease. | 2018 | Details |
| A13118 | 30131870 | NPJ Syst Biol Appl | Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease. | 2018 | Details |
| A13151 | 30113367 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease: current concepts, epidemiology and management strategies. | 2018 | Details |
| A13210 | 30081580 | Nutrients | Paeoniflorin Ameliorates Fructose-Induced Insulin Resistance and Hepatic Steatosis by Activating LKB1/AMPK and AKT Pathways. | 2018 | Details |
| A13260 | 30060614 | Nutrients | French Recommendations for Sugar Intake in Adults: A Novel Approach Chosen by ANSES. | 2018 | Details |
| A13327 | 30029691 | Cardiovasc Diabetol | Beneficial effects of cherry consumption as a dietary intervention for metabolic, hepatic and vascular complications in type 2 diabetic rats. | 2018 | Details |
| A13334 | 30026731 | Front Endocrinol (Lausanne) | Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. | 2018 | Details |
| A13335 | 30026676 | Food Nutr Res | Bitter melon extract ameliorates palmitate-induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 cells and high-fat/high-fructose-diet-induced fatty liver. | 2018 | Details |
| A13336 | 30026586 | Sci Rep | Substitution of linoleic acid with α-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis. | 2018 | Details |
| A13381 | 30009570 | Physiol Rep | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | 2018 | Details |
| A13382 | 30009361 | Folia Morphol (Warsz) | The differential effects of high-fat and high- -fructose diets on the liver of male albino rat and the proposed underlying mechanisms. | 2018 | Details |
| A13413 | 29990551 | Biochim Biophys Acta Mol Basis Dis | Animal models of NAFLD from a hepatologist's point of view. | 2018 | Details |
| A13416 | 29989845 | Metab Syndr Relat Disord | Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome. | 2018 | Details |
| A13433 | 29975946 | Cell Physiol Biochem | Decreased Hepatic Lactotransferrin Induces Hepatic Steatosis in Chronic Non-Alcoholic Fatty Liver Disease Model. | 2018 | Details |
| A13454 | 29964102 | Int J Biol Macromol | Chicory (Cichorium intybus L.) polysaccharides attenuate high-fat diet induced non-alcoholic fatty liver disease via AMPK activation. | 2018 | Details |
| A13464 | 29959418 | Lab Invest | Characterization of a murine nonalcoholic steatohepatitis model induced by high fat high calorie diet plus fructose and glucose in drinking water. | 2018 | Details |
| A13533 | 29927747 | J Complement Integr Med | Terminalia Sericea aqueous leaf extract protects growing wistar rats against fructose-induced fatty liver disease. | 2018 | Details |
| A13534 | 29926176 | Eur J Nutr | Lack of liver steatosis in germ-free mice following hypercaloric diets. | 2018 | Details |
| A13632 | 29861476 | Nutrients | IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice. | 2018 | Details |
| A13636 | 29860219 | Biomed Pharmacother | Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice. | 2018 | Details |
| A13704 | 29800612 | Eur J Pharm Sci | Novel therapeutic drug identification and gene correlation for fatty liver disease using high-content screening: Proof of concept. | 2018 | Details |
| A13721 | 29792584 | J Dev Orig Health Dis | Neonatal intake of oleanolic acid attenuates the subsequent development of high fructose diet-induced non-alcoholic fatty liver disease in rats. | 2018 | Details |
| A13724 | 29790582 | Hepatology | Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents. | 2018 | Details |
| A13740 | 29781841 | Curr Opin Clin Nutr Metab Care | Carbohydrates and diet patterns in nonalcoholic fatty liver disease in children and adolescents. | 2018 | Details |
| A13744 | 29779170 | Eur J Nutr | Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial. | 2018 | Details |
| A13789 | 29756964 | Nutr Hosp | Açai improves non-alcoholic fatty liver disease (NAFLD) induced by fructose. | 2018 | Details |
| A13797 | 29751074 | Food Chem Toxicol | Effects of high fructose intake on liver injury progression in high fat diet induced fatty liver disease in ovariectomized female mice. | 2018 | Details |
| A13847 | 29729104 | Liver Transpl | The impact of diet-induced hepatic steatosis in a murine model of hepatic ischemia/reperfusion injury. | 2018 | Details |
| A13865 | 29719880 | Drug Res (Stuttg) | Ethanol Extract of Crataegus Oxyacantha L. Ameliorate Dietary Non-Alcoholic Fatty Liver Disease in Rat. | 2018 | Details |
| A13878 | 29713129 | World J Gastroenterol | Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. | 2018 | Details |
| A13910 | 29697539 | Curr Opin Clin Nutr Metab Care | Dietary carbohydrates and fatty liver disease: de novo lipogenesis. | 2018 | Details |
| A13962 | 29670844 | Adv Pharm Bull | The Eeffect of Metformin Combined with Calcium-Vitamin D3 Against Diet-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13986 | 29656466 | Int J Exp Pathol | Evaluation of high-fat high-fructose diet treatment in factor VIII (coagulation factor)-deficient mouse model. | 2018 | Details |
| A13992 | 29654490 | Mol Neurobiol | Long-Term, Fructose-Induced Metabolic Syndrome-Like Condition Is Associated with Higher Metabolism, Reduced Synaptic Plasticity and Cognitive Impairment in Octodon degus. | 2018 | Details |
| A14008 | 29637446 | J Physiol Biochem | Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients. | 2018 | Details |
| A14013 | 29634314 | Am J Physiol Endocrinol Metab | Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis. | 2018 | Details |
| A14129 | 29572095 | J Hepatol | A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer. | 2018 | Details |
| A14172 | 29552625 | Cell Mol Gastroenterol Hepatol | Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2). | 2017 | Details |
| A14195 | 29534506 | Nutrients | Saccharin Increases Fasting Blood Glucose but Not Liver Insulin Resistance in Comparison to a High Fructose-Fed Rat Model. | 2018 | Details |
| A14224 | 29516496 | J Physiol | Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation. | 2018 | Details |
| A14225 | 29516226 | Eur J Nutr | Chronic fructose intake does not induce liver steatosis and inflammation in female Sprague-Dawley rats, but causes hypertriglyceridemia related to decreased VLDL receptor expression. | 2018 | Details |
| A14247 | 29507217 | Proc Natl Acad Sci U S A | High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism. | 2018 | Details |
| A14260 | 29498345 | Br J Nutr | 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. | 2018 | Details |
| A14274 | 29488485 | Ter Arkh | [Nonalcoholic fatty liver disease without obesity: the problem to be solved]. | 2019 | Details |
| A14289 | 29481986 | J Nutr Biochem | Replacement of soybean oil by fish oil increases cytosolic lipases activities in liver and adipose tissue from rats fed a high-carbohydrate diets. | 2018 | Details |
| A14345 | 29454967 | Biochem Biophys Res Commun | SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation. | 2018 | Details |
| A14358 | 29450137 | Biochim Open | Liver and Metformin: Lessons of a fructose diet in mice. | 2017 | Details |
| A14377 | 29438460 | Adv Nutr | Practical Dietary Recommendations for the Prevention and Management of Nonalcoholic Fatty Liver Disease in Adults. | 2018 | Details |
| A14411 | 29420066 | Am J Physiol Gastrointest Liver Physiol | CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease. | 2018 | Details |
| A14413 | 29419350 | Ultrastruct Pathol | Swim exercise training ameliorates hepatocyte ultrastructural alterations in rats fed on a high fat and sugar diet. | 2018 | Details |
| A14429 | 29410708 | Diabetol Metab Syndr | Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats. | 2018 | Details |
| A14435 | 29408694 | J Hepatol | Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. | 2018 | Details |
| A14469 | 29398867 | World J Gastroenterol | Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. | 2018 | Details |
| A14512 | 29375205 | World J Gastroenterol | INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis. | 2018 | Details |
| A14513 | 29375204 | World J Gastroenterol | Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis. | 2018 | Details |
| A14519 | 29371918 | Oncotarget | Long-term administration of tacrolimus and everolimus prevents high cholesterol-high fructose-induced steatosis in C57BL/6J mice by inhibiting de-novo lipogenesis. | 2017 | Details |
| A14567 | 29350757 | J Food Sci | Hepatoprotective Effects of Sophoricoside against Fructose-Induced Liver Injury via Regulating Lipid Metabolism, Oxidation, and Inflammation in Mice. | 2018 | Details |
| A14665 | 29298969 | Pol Merkur Lekarski | [Dietetary recommendation for non-alcoholic fatty liver disease]. | 2017 | Details |
| A14709 | 29277999 | Rev Esp Enferm Dig | Nonalcoholic steatohepatitis and hepatic adenomatosis: casual or causal relationship? | 2018 | Details |
| A14714 | 29274591 | Biomed Pharmacother | Extract of Citrus maxima (pummelo) leaves improve hepatoprotective activity in Wistar rats submitted to the induction of non-alcoholic hepatic steatosis. | 2017 | Details |
| A14721 | 29271886 | Nutrients | A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome. | 2017 | Details |
| A14741 | 29263303 | JCI Insight | Intestinal, but not hepatic, ChREBP is required for fructose tolerance. | 2017 | Details |
| A14751 | 29255346 | Drug Des Devel Ther | Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes. | 2017 | Details |
| A14767 | 29248461 | Am J Pathol | Knockout of l-Histidine Decarboxylase Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling. | 2017 | Details |
| A14782 | 29235014 | Obes Surg | Increased Bile Acid Signals After Duodenal-Jejunal Bypass Improve Non-alcoholic Steatohepatitis (NASH) in a Rodent Model of Diet-Induced NASH. | 2018 | Details |
| A14785 | 29234288 | Front Physiol | Lipocalin-2 in Fructose-Induced Fatty Liver Disease. | 2017 | Details |
| A14801 | 29225114 | Prog Cardiovasc Dis | Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity. | 2017 | Details |
| A14810 | 29222961 | Liver Int | Liver zonation in children with non-alcoholic fatty liver disease: Associations with dietary fructose and uric acid concentrations. | 2018 | Details |
| A14861 | 29201200 | Exp Ther Med | Effect of a stilbene glycoside-rich extract from Polygoni Multiflori Radix on experimental non-alcoholic fatty liver disease based on principal component and orthogonal partial least squares discriminant analysis. | 2017 | Details |
| A14885 | 29191128 | Biosci Biotechnol Biochem | Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells. | 2017 | Details |
| A14941 | 29164049 | J Transl Int Med | Polyphenols Treatment in Patients with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A14957 | 29156529 | Biomed Pharmacother | Alpinetin improved high fat diet-induced non-alcoholic fatty liver disease (NAFLD) through improving oxidative stress, inflammatory response and lipid metabolism. | 2017 | Details |
| A14975 | 29149647 | J Nutr Biochem | Dietary fish oil differentially ameliorates high-fructose diet-induced hepatic steatosis and hyperlipidemia in mice depending on time of feeding. | 2017 | Details |
| A15048 | 29118995 | Open Heart | Added fructose as a principal driver of non-alcoholic fatty liver disease: a public health crisis. | 2017 | Details |
| A15065 | 29113028 | Hepatology | Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis. | 2018 | Details |
| A15100 | 29096730 | Gene Expr | Updates on Dietary Models of Nonalcoholic Fatty Liver Disease: Current Studies and Insights. | 2017 | Details |
| A15157 | 29069580 | Eur J Pharmacol | Nicotinamide prevents sweet beverage-induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress. | 2017 | Details |
| A15243 | 29025734 | Am J Physiol Gastrointest Liver Physiol | Dietary copper-fructose interactions alter gut microbial activity in male rats. | 2017 | Details |
| A15251 | 29023819 | Hepatology | Nonalcoholic fatty liver disease impairs expression of the type II inositol 1,4,5-trisphosphate receptor. | 2018 | Details |
| A15288 | 28986308 | Biochim Biophys Acta Mol Basis Dis | n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD. | 2017 | Details |
| A15305 | 28972878 | Discov Med | Role of nutrition, gene polymorphism, and gut microbiota in non-alcoholic fatty liver disease. | 2017 | Details |
| A15306 | 28972610 | Food Funct | fat-1 mice prevent high-fat plus high-sugar diet-induced non-alcoholic fatty liver disease. | 2017 | Details |
| A15307 | 28972537 | J Clin Invest | Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. | 2017 | Details |
| A15313 | 28970836 | Front Immunol | Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease. | 2017 | Details |
| A15341 | 28956816 | Nutrients | Qualitative and Quantitative Evaluation of Dietary Intake in Patients with Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A15376 | 28939830 | Sci Rep | Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD. | 2017 | Details |
| A15383 | 28936403 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease in Lean Subjects: Characteristics and Implications. | 2017 | Details |
| A15396 | 28931589 | J Nutr | Oral Supplementation of Glutamine Attenuates the Progression of Nonalcoholic Steatohepatitis in C57BL/6J Mice. | 2017 | Details |
| A15407 | 28926951 | Nutrients | Insights into the Hexose Liver Metabolism-Glucose versus Fructose. | 2017 | Details |
| A15439 | 28906444 | Nutrients | Short-Term Intake of a Fructose-, Fat- and Cholesterol-Rich Diet Causes Hepatic Steatosis in Mice: Effect of Antibiotic Treatment. | 2017 | Details |
| A15454 | 28899857 | Am J Physiol Endocrinol Metab | High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine. | 2017 | Details |
| A15465 | 28894517 | Middle East J Dig Dis | Effects of Probiotic and Prebiotic Supplementation on Leptin, Adiponectin, and Glycemic Parameters in Non-alcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2017 | Details |
| A15489 | 28878197 | Nutrients | Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A15500 | 28874443 | J Lipid Res | Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate. | 2017 | Details |
| A15507 | 28869588 | Lab Invest | Activation of pluripotent genes in hepatic progenitor cells in the transition of nonalcoholic steatohepatitis to pre-malignant lesions. | 2017 | Details |
| A15511 | 28868179 | World J Gastrointest Pathophysiol | Fatty liver without a large "belly": Magnified review of non-alcoholic fatty liver disease in non-obese patients. | 2017 | Details |