Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25403 | 21886908 | Sci Pharm | Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines. | 2011 | Details |
| A25410 | 21881966 | Metab Brain Dis | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. | 2011 | Details |
| A25411 | 21880110 | BJOG | A novel cause for abnormal liver function tests in pregnancy and the puerperium: non-alcoholic fatty liver disease. | 2011 | Details |
| A25420 | 21875310 | Crit Rev Clin Lab Sci | Non-alcoholic fatty liver disease. | 2011 | Details |
| A25422 | 21873555 | FASEB J | Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet. | 2011 | Details |
| A25426 | 21862168 | Diabetes Res Clin Pract | Serum sex hormone-binding globulin levels are independently associated with nonalcoholic fatty liver disease in people with type 2 diabetes. | 2011 | Details |
| A25432 | 21853118 | PLoS One | Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. | 2011 | Details |
| A25438 | 21841322 | Intern Med | Serum dehydroepiandrosterone sulphate levels in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25439 | 21840395 | Biochim Biophys Acta | Genetic modifiers of non-alcoholic fatty liver disease progression. | 2011 | Details |
| A25440 | 21839075 | Eur J Pharmacol | Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver. | 2011 | Details |
| A25443 | 21836057 | Am J Physiol Gastrointest Liver Physiol | Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. | 2011 | Details |
| A25450 | 21818154 | Obesity (Silver Spring) | Perinephric and epididymal fat affect hepatic metabolism in rats. | 2011 | Details |
| A25454 | 21816784 | J Clin Endocrinol Metab | Nonalcoholic fatty liver disease is associated with low circulating levels of insulin-like growth factor-I. | 2011 | Details |
| A25460 | 21808028 | Proc Natl Acad Sci U S A | Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. | 2011 | Details |
| A25469 | 21799478 | Obesity (Silver Spring) | Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. | 2011 | Details |
| A25471 | 21796479 | Endocrine | Coexistence of non-alcoholic fatty liver disease with elevated alanine aminotransferase is associated with insulin resistance in young Han males. | 2011 | Details |
| A25473 | 21794038 | Hepatol Res | Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels. | 2011 | Details |
| A25475 | 21793029 | Hepatology | Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. | 2011 | Details |
| A25477 | 21790685 | Aliment Pharmacol Ther | Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25480 | 21787451 | Br J Nutr | Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice. | 2011 | Details |
| A25484 | 21778625 | Nihon Ronen Igakkai Zasshi | [Organs related to glucose metabolism and aging in animal models]. | 2011 | Details |
| A25485 | 21777557 | J Hepatol | The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver. | 2011 | Details |
| A25489 | 21773052 | J Lipids | Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation. | 2011 | Details |
| A25491 | 21770819 | Scand J Gastroenterol | Circulating vaspin and its relationship with insulin sensitivity, adiponectin, and liver histology in subjects with non-alcoholic steatohepatitis. | 2011 | Details |
| A25499 | 21765869 | Therap Adv Gastroenterol | The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis. | 2011 | Details |
| A25500 | 21764575 | J Nutr Biochem | Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice. | 2011 | Details |
| A25501 | 21764273 | Nutr Metab Cardiovasc Dis | Obesity and metabolic syndrome: potential benefit from specific nutritional components. | 2011 | Details |
| A25502 | 21764223 | Med Hypotheses | Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease. | 2011 | Details |
| A25503 | 21762556 | Respir Care | Influence of obstructive sleep apnea on fatty liver disease: role of chronic intermittent hypoxia. | 2011 | Details |
| A25505 | 21760546 | J Pediatr Gastroenterol Nutr | Effect of a 10-week weight loss camp on fatty liver disease and insulin sensitivity in obese Danish children. | 2012 | Details |
| A25508 | 21742296 | Clin Res Hepatol Gastroenterol | Liver fibrogenesis and metabolic factors. | 2011 | Details |
| A25510 | 21755261 | Braz J Med Biol Res | Effect of silybin on high-fat-induced fatty liver in rats. | 2011 | Details |
| A25520 | 21748765 | Hepatology | Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial. | 2011 | Details |
| A25523 | 21745307 | Liver Int | PNPLA3 polymorphism influences liver fibrosis in unselected patients with type 2 diabetes. | 2011 | Details |
| A25527 | 21745282 | Liver Int | The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population. | 2011 | Details |
| A25528 | 21745271 | Liver Int | Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis. | 2011 | Details |
| A25538 | 21735081 | Dig Dis Sci | Nonalcoholic fatty liver disease markers are associated with insulin resistance in type 1 diabetes. | 2011 | Details |
| A25539 | 21734787 | World J Gastroenterol | Adiponectin, a key adipokine in obesity related liver diseases. | 2011 | Details |
| A25540 | 21734391 | Dig Dis | Pathophysiology of non-alcoholic steatohepatitis and basis for treatment. | 2011 | Details |
| A25545 | 21727734 | Saudi J Gastroenterol | Genetic polymorphisms in non-alcoholic fatty liver disease in obese Egyptian children. | 2011 | Details |
| A25546 | 21727730 | Saudi J Gastroenterol | Insulin resistance, steatosis, and fibrosis in Egyptian patients with chronic Hepatitis C virus infection. | 2011 | Details |
| A25552 | 21723084 | Presse Med | [Nonalcoholic fatty liver disease]. | 2011 | Details |
| A25553 | 21718726 | J Hepatol | Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target. | 2011 | Details |
| A25562 | 21709958 | Arq Gastroenterol | Hepatic and biochemical repercussions of a polyunsaturated fat-rich hypercaloric and hyperlipidic diet in Wistar rats. | 2012 | Details |
| A25563 | 21708823 | Gut | Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. | 2011 | Details |
| A25567 | 21704120 | Mol Cell Endocrinol | Postprandial triglyceride-rich lipoproteins induce hepatic insulin resistance in HepG2 cells independently of their receptor-mediated cellular uptake. | 2011 | Details |
| A25569 | 21703998 | Gastroenterology | Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis. | 2011 | Details |
| A25571 | 21703200 | J Hepatol | The role of thiazolidinediones in non-alcoholic steatohepatitis - a systematic review and meta analysis. | 2011 | Details |
| A25573 | 21703181 | J Hepatol | Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese. | 2011 | Details |
| A25577 | 21700865 | Science | Human fatty liver disease: old questions and new insights. | 2011 | Details |
| A25578 | 21697744 | J Pediatr Gastroenterol Nutr | Biochemical parameters and anthropometry predict NAFLD in obese children. | 2011 | Details |
| A25582 | 21690266 | J Lipid Res | Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. | 2011 | Details |
| A25594 | 21674556 | Hepatology | Role of ethnicity in overweight and obese patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A25602 | 21664213 | Clin Res Hepatol Gastroenterol | Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: mechanisms and pathophysiological role. | 2011 | Details |
| A25603 | 21663607 | Lipids Health Dis | Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans. | 2011 | Details |
| A25607 | 21655948 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2011 | Details |
| A25608 | 21654360 | Adv Anat Pathol | Update on fatty liver disease and steatohepatitis. | 2011 | Details |
| A25609 | 21651352 | Expert Rev Gastroenterol Hepatol | Animal models in the study of hepatitis C virus-associated liver pathologies. | 2011 | Details |
| A25624 | 21633178 | J Clin Invest | The role of lipid droplets in metabolic disease in rodents and humans. | 2011 | Details |
| A25627 | 21629127 | J Pediatr Gastroenterol Nutr | Mechanisms of lipotoxicity in NAFLD and clinical implications. | 2011 | Details |
| A25641 | 21612059 | Vnitr Lek | [Steatosis and steatohepatitis in diabetic patient]. | 2011 | Details |
| A25642 | 21604917 | Ann Med | The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for hepatic steatosis. | 2011 | Details |
| A25647 | 21599535 | Crit Rev Biochem Mol Biol | Insulin signaling to hepatic lipid metabolism in health and disease. | 2011 | Details |
| A25651 | 21593806 | Obesity (Silver Spring) | Downregulation of hepatic glucose-6-phosphatase-α in patients with hepatic steatosis. | 2011 | Details |
| A25653 | 21587068 | Curr Opin Clin Nutr Metab Care | The 5-lipoxygenase/leukotriene pathway in obesity, insulin resistance, and fatty liver disease. | 2011 | Details |
| A25658 | 21570653 | Eur J Intern Med | Alterations in lipid, carbohydrate and iron metabolism in patients with non-alcoholic steatohepatitis (NASH) and metabolic syndrome. | 2011 | Details |
| A25664 | 21565756 | Orv Hetil | [Clinical correlations of chronic hepatitis C, diabetes mellitus and steatohepatitis]. | 2011 | Details |
| A25666 | 21564529 | Am J Transplant | Should metformin be our antiglycemic agent of choice post-transplantation? | 2011 | Details |
| A25671 | 21562784 | Dig Dis Sci | Fatty liver is associated with recurrent bacterial infections independent of metabolic syndrome. | 2011 | Details |
| A25672 | 21562757 | Diabetologia | Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice. | 2011 | Details |
| A25674 | 21561285 | Scand J Gastroenterol | Overweight and hypertriglyceridemia are risk factors for liver cirrhosis in middle-aged Swedish men. | 2011 | Details |
| A25676 | 21559749 | Intern Emerg Med | Is nonalcoholic steatohepatitis associated with a high-though-normal thyroid stimulating hormone level and lower cholesterol levels? | 2011 | Details |
| A25680 | 21557024 | Hepatol Int | Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network. | 2011 | Details |
| A25681 | 21556019 | Nat Rev Endocrinol | Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. | 2011 | Details |
| A25683 | 21549113 | Eur J Pharmacol | Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease. | 2011 | Details |
| A25684 | 21547049 | J Ayurveda Integr Med | A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease. | 2010 | Details |
| A25686 | 21545576 | Br J Pharmacol | Resistin: functional roles and therapeutic considerations for cardiovascular disease. | 2012 | Details |
| A25687 | 21543214 | J Nutr Biochem | Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver. | 2011 | Details |
| A25691 | 21538280 | Semin Liver Dis | Genetics of alcoholic and nonalcoholic fatty liver disease. | 2011 | Details |
| A25695 | 21534339 | Turk J Pediatr | Abdominal obesity is an independent risk factor for increased carotid intima- media thickness in obese children. | 2011 | Details |
| A25703 | 21521307 | Clin Endocrinol (Oxf) | Correlation of insulin sensitivity with bone mineral status in obese adolescents with nonalcoholic fatty liver disease. | 2011 | Details |
| A25711 | 21518734 | Arch Dis Child | Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement. | 2011 | Details |
| A25719 | 21509233 | Sultan Qaboos Univ Med J | Non-Alcoholic Fatty Liver Disease (NAFLD) - Is it an Emerging Risk Factor for Coronary Artery Disease?: Preliminary study in a local Indian population. | 2010 | Details |
| A25735 | 21495873 | Toxicol Mech Methods | Epigenetic priming of the metabolic syndrome. | 2011 | Details |
| A25736 | 21494075 | Korean J Hepatol | Association of serum alanine aminotransferase and γ-glutamyltransferase levels within the reference range with metabolic syndrome and nonalcoholic fatty liver disease. | 2011 | Details |
| A25749 | 21484130 | Hepatol Int | Renal function and severity of bright liver. Relationship with insulin resistance, intrarenal resistive index, and glomerular filtration rate. | 2011 | Details |
| A25753 | 21479224 | PLoS One | Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation. | 2011 | Details |
| A25756 | 21476922 | Expert Rev Gastroenterol Hepatol | Insulin resistance in nonalcoholic steatohepatitis: necessary but not sufficient - death of a dogma from analysis of therapeutic studies? | 2011 | Details |
| A25757 | 21476921 | Expert Rev Gastroenterol Hepatol | Organelle dysfunction in hepatitis C virus-associated steatosis: anything to learn from nonalcoholic steatohepatitis? | 2011 | Details |
| A25763 | 21476915 | Expert Rev Gastroenterol Hepatol | Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications. | 2011 | Details |
| A25764 | 21476914 | Expert Rev Gastroenterol Hepatol | Inflammation in nonalcoholic steatohepatitis. | 2011 | Details |
| A25767 | 21476911 | Expert Rev Gastroenterol Hepatol | Autophagy in nonalcoholic steatohepatitis. | 2011 | Details |
| A25772 | 21475632 | Int J Gen Med | The effects of diet-induced obesity on hepatocyte insulin signaling pathways and induction of non-alcoholic liver damage. | 2011 | Details |
| A25776 | 21472332 | Mol Med Rep | Mammalian target of the rapamycin pathway is involved in non-alcoholic fatty liver disease. | 2010 | Details |
| A25780 | 21463618 | Eur J Pharmacol | A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. | 2011 | Details |
| A25788 | 21455726 | Diabetologia | Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease. | 2011 | Details |
| A25794 | 21449949 | Diabetes Obes Metab | Current therapeutic strategies in non-alcoholic fatty liver disease. | 2011 | Details |
| A25797 | 22813407 | Diabetes Metab Syndr | Association of nonalcoholic fatty liver disease with metabolic syndrome in Indian population. | 2012 | Details |
| A25800 | 21446920 | Clin Sci (Lond) | Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine. | 2011 | Details |
| A25801 | 21445622 | Eur J Nutr | Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats. | 2011 | Details |