Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19108 | 26761430 | PLoS One | Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? | 2016 | Details |
| A19114 | 26755867 | World J Gastroenterol | Association between hepatitis B and metabolic syndrome: Current state of the art. | 2016 | Details |
| A19115 | 26755815 | J Investig Med | Plasma thyroid hormone concentration is associated with hepatic triglyceride content in patients with type 2 diabetes. | 2015 | Details |
| A19117 | 26753695 | Naunyn Schmiedebergs Arch Pharmacol | Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis. | 2016 | Details |
| A19118 | 26749582 | Aliment Pharmacol Ther | Aspirin use is associated with lower indices of liver fibrosis among adults in the United States. | 2016 | Details |
| A19123 | 26745268 | PLoS One | A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice. | 2016 | Details |
| A19129 | 26742762 | Hepatol Int | Fibrosis assessment: impact on current management of chronic liver disease and application of quantitative invasive tools. | 2016 | Details |
| A19135 | 26734800 | Arq Bras Cir Dig | COMPARISON OF HEPATIC PROFILE IN PRE AND POSTOPERATIVE OF BARIATRIC SURGERY: PRIVATE VS PUBLIC NETWORK. | 2016 | Details |
| A19142 | 26731267 | PLoS One | The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice. | 2016 | Details |
| A19143 | 26730275 | World J Hepatol | Management of non-alcoholic fatty liver disease in 2015. | 2015 | Details |
| A19148 | 26728044 | BMC Cancer | MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice. | 2016 | Details |
| A19150 | 26727365 | PLoS One | Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats. | 2016 | Details |
| A19154 | 26725900 | Liver Int | Follow-up of patients with chronic hepatitis C and a sustained viral response. | 2016 | Details |
| A19155 | 26725058 | Dig Dis Sci | Function of Autophagy in Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A19165 | 30284430 | Eksp Klin Gastroenterol | [MALABSORPTION FAT-SOLUBLE VITAMINS AND PROSPECTS OF THEIR USE IN LIVER DISEASES]. | 2018 | Details |
| A19166 | 30284418 | Eksp Klin Gastroenterol | [ASSESSMENT OF MATRIX METALLOPROTEINASES AND THEIR TISSUE INHIBITORS FOR NON-INVASIVE DIAGNOSIS OF LIVER FIBROSIS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE]. | 2018 | Details |
| A19170 | 30280550 | Eksp Klin Gastroenterol | [PREDICTION OF LIVER FIBROSIS IN PATIENTS WITH CHRONIC HEART FAILURE AND METABOLIC SYNDROME]. | 2018 | Details |
| A19177 | 29889400 | Eksp Klin Gastroenterol | THE HEPATOPROTECTOR ROPREN FOR THE TREATMENT OF PATIENTS WITH NONALCOHOLIC STEATOHEPATITIS: A PROSPECTIVE OBSERVATIONAL STUDY. | 2018 | Details |
| A19183 | 29190058 | Duodecim | Diagnosis of nonalcoholic fatty liver disease (NAFLD). | 2018 | Details |
| A19184 | 29188949 | Duodecim | Fatty liver - so what? | 2018 | Details |
| A19190 | 28332698 | Mol Med | Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol. | 2017 | Details |
| A19193 | 26715612 | Lab Med | Selected Noninvasive Markers in Diagnosing Liver Diseases. | 2015 | Details |
| A19194 | 26713759 | Liver Int | Performance of non-invasive models of fibrosis in predicting mild to moderate fibrosis in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A19196 | 26713058 | J Korean Med Sci | Vitamin D Status and Bone Mineral Density in Obese Children with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19200 | 26707365 | Hepatology | Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. | 2016 | Details |
| A19202 | 26707008 | Liver Transpl | Prevalence and risk factors of steatosis after liver transplantation and patient outcomes. | 2016 | Details |
| A19208 | 26703097 | Trends Endocrinol Metab | The Role of Cholesterol in the Pathogenesis of NASH. | 2015 | Details |
| A19212 | 26699145 | J Pharmacol Exp Ther | ASB14780, an Orally Active Inhibitor of Group IVA Phospholipase A2, Is a Pharmacotherapeutic Candidate for Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19217 | 26698379 | Hepatology | Weight loss results in significant improvements in quality of life for patients with nonalcoholic fatty liver disease: A prospective cohort study. | 2016 | Details |
| A19223 | 26695085 | J Gastroenterol Hepatol | Treatment with geraniol ameliorates methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in rats. | 2016 | Details |
| A19231 | 26683320 | Hepatol Int | Genetic and epigenetic mechanisms of NASH. | 2015 | Details |
| A19233 | 26682925 | Biochem Biophys Res Commun | DSS colitis promotes tumorigenesis and fibrogenesis in a choline-deficient high-fat diet-induced NASH mouse model. | 2015 | Details |
| A19241 | 26677985 | Gastroenterology | Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient Elastography. | 2015 | Details |
| A19242 | 26676813 | Semin Liver Dis | Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19243 | 26676626 | Hepatol Int | High FIB-4 index as an independent risk factor of prevalent chronic kidney disease in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A19244 | 26675585 | BBA Clin | Clinical spectrum of non-alcoholic fatty liver disease in diabetic and non-diabetic patients. | 2014 | Details |
| A19254 | 26672595 | PLoS One | Obstructive Sleep Apnea Is Associated with Liver Damage and Atherosclerosis in Patients with Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A19256 | 26670487 | Am J Physiol Endocrinol Metab | Metabolic phenotype and adipose and liver features in a high-fat Western diet-induced mouse model of obesity-linked NAFLD. | 2015 | Details |
| A19261 | 26667698 | Nutr Hosp | MEDITERRANEAN DIET IS ASSOCIATED WITH LIVER HISTOLOGY IN PATIENTS WITH NON ALCOHOLIC FATTY LIVER DISEASE. | 2015 | Details |
| A19262 | 26667615 | Vnitr Lek | [Approach to patients with liver diseases]. | 2015 | Details |
| A19264 | 26667070 | Annu Rev Physiol | Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19270 | 26664666 | Ont Health Technol Assess Ser | Transient Elastography and Controlled Attenuation Parameter for Diagnosing Liver Fibrosis and Steatosis in Ontario: An Economic Analysis. | 2015 | Details |
| A19271 | 26663351 | Hepatology | Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice. | 2016 | Details |
| A19276 | 26662852 | Hepatology | NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice. | 2016 | Details |
| A19278 | 26659452 | Hepatology | Liver stiffness in nonalcoholic fatty liver disease: A comparison of supersonic shear imaging, FibroScan, and ARFI with liver biopsy. | 2016 | Details |
| A19282 | 26655953 | J Biol Chem | Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice. | 2015 | Details |
| A19289 | 26648069 | Curr Drug Targets | Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib. | 2016 | Details |
| A19293 | 26644818 | World J Hepatol | Vitamin E reduces liver stiffness in nonalcoholic fatty liver disease. | 2015 | Details |
| A19302 | 26638195 | Hepatology | Portal inflammation is independently associated with fibrosis and metabolic syndrome in pediatric nonalcoholic fatty liver disease. | 2016 | Details |
| A19304 | 26638128 | Hepatology | Sarcopenia is associated with significant liver fibrosis independently of obesity and insulin resistance in nonalcoholic fatty liver disease: Nationwide surveys (KNHANES 2008-2011). | 2016 | Details |
| A19305 | 26637970 | Hepatology | Mutant p53 in concert with an interleukin-27 receptor alpha deficiency causes spontaneous liver inflammation, fibrosis, and steatosis in mice. | 2016 | Details |
| A19308 | 26636408 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver is not associated with incident chronic kidney disease: a large histology-based comparison with healthy individuals. | 2016 | Details |
| A19310 | 26635079 | BMC Gastroenterol | Gut microbiota manipulation with prebiotics in patients with non-alcoholic fatty liver disease: a randomized controlled trial protocol. | 2015 | Details |
| A19313 | 26634783 | Expert Rev Gastroenterol Hepatol | The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis: a 2015 update. | 2015 | Details |
| A19314 | 26634687 | Clin Med (Lond) | An overview of the genetics, mechanisms and management of NAFLD and ALD. | 2015 | Details |
| A19317 | 26632897 | Medicine (Baltimore) | Visceral Obesity Predicts Significant Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19324 | 26629307 | J Radiol Case Rep | Minimally invasive percutaneous endovascular therapies in the management of complications of non-alcoholic fatty liver disease (NAFLD): A case report. | 2015 | Details |
| A19330 | 26626909 | Dig Dis Sci | Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame. | 2015 | Details |
| A19335 | 26623270 | J Clin Transl Hepatol | Treatment of Nonalcoholic Fatty Liver Disease: The Role of Medical, Surgical, and Endoscopic Weight Loss. | 2015 | Details |
| A19338 | 26621325 | J Diabetes | Soluble epoxide hydrolase: A potential target for metabolic diseases. | 2016 | Details |
| A19342 | 26620035 | Mymensingh Med J | Non-alcoholic Fatty Liver Disease (NAFLD)--A Review. | 2015 | Details |
| A19350 | 26613528 | Horm Res Paediatr | Early Glucose Derangement Detected by Continuous Glucose Monitoring and Progression of Liver Fibrosis in Nonalcoholic Fatty Liver Disease: An Independent Predictive Factor? | 2015 | Details |
| A19354 | 26610680 | Radiologe | [Functional MR imaging of the liver]. | 2015 | Details |
| A19355 | 26610348 | Gut Liver | Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan. | 2016 | Details |
| A19357 | 26609343 | World J Hepatol | Challenges of liver cancer: Future emerging tools in imaging and urinary biomarkers. | 2015 | Details |
| A19360 | 26608256 | Lancet | Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study. | 2015 | Details |
| A19361 | 26606259 | Expert Rev Gastroenterol Hepatol | Circulating microRNAs in nonalcoholic fatty liver disease. | 2015 | Details |
| A19363 | 26603489 | Sci Rep | Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. | 2015 | Details |
| A19364 | 26603137 | Am J Pathol | Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling. | 2015 | Details |
| A19366 | 26602577 | P R Health Sci J | A Comparison of Brunt's Criteria, the Non-Alcoholic Fatty Liver Disease Activity Score (NAS), and a Proposed NAS Scoring that Includes Fibrosis in Non-Alcoholic Fatty Liver Disease Staging. | 2015 | Details |
| A19372 | 26600967 | World J Gastrointest Pathophysiol | Starring role of toll-like receptor-4 activation in the gut-liver axis. | 2015 | Details |
| A19373 | 26600855 | Res Pharm Sci | Effects of rosuvastatin and/or β-carotene on non-alcoholic fatty liver in rats. | 2015 | Details |
| A19376 | 26600078 | Hepatology | The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota. | 2016 | Details |
| A19381 | 26599080 | PLoS One | The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection. | 2015 | Details |
| A19385 | 26597602 | J Diabetes Complications | Chronic fructose intake accelerates non-alcoholic fatty liver disease in the presence of essential hypertension. | 2015 | Details |
| A19386 | 26596542 | J Hepatol | MERTK rs4374383 polymorphism affects the severity of fibrosis in non-alcoholic fatty liver disease. | 2015 | Details |
| A19387 | 26594831 | J Pediatr Gastroenterol Nutr | Liver Disease in Pediatric Patients With Ataxia Telangiectasia: A Novel Report. | 2016 | Details |
| A19391 | 26593434 | Eur J Pharmacol | Protective role of autophagy in methionine-choline deficient diet-induced advanced nonalcoholic steatohepatitis in mice. | 2015 | Details |
| A19394 | 26592838 | Eur Rev Med Pharmacol Sci | The expression of serum M30 and M65 in chronic hepatitis B patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A19397 | 26592354 | J Hepatol | FibroGENE: A gene-based model for staging liver fibrosis. | 2015 | Details |
| A19414 | 26581806 | Sci Rep | Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis. | 2015 | Details |
| A19417 | 26580662 | J Clin Med | MicroRNA Expression Relating to Dietary-Induced Liver Steatosis and NASH. | 2015 | Details |
| A19420 | 26576787 | J Med Ultrason (2001) | Usefulness of ultrasonographic estimation of preperitoneal and subcutaneous fat thickness in the diagnosis of nonalcoholic fatty liver disease in diabetic patients. | 2015 | Details |
| A19424 | 26576055 | PLoS One | Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls. | 2015 | Details |
| A19425 | 26573228 | Oncotarget | LPS-induced TNF-α factor mediates pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease. | 2015 | Details |
| A19435 | 26571018 | PLoS One | High Dietary Sodium Intake Assessed by Estimated 24-h Urinary Sodium Excretion Is Associated with NAFLD and Hepatic Fibrosis. | 2015 | Details |
| A19439 | 26567858 | Respirology | Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials. | 2015 | Details |
| A19442 | 26567194 | Adv Nutr | Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer. | 2015 | Details |
| A19450 | 26564718 | Am J Physiol Gastrointest Liver Physiol | Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver. | 2015 | Details |
| A19453 | 26560734 | Hepatology | Magnetic resonance elastography is superior to acoustic radiation force impulse for the Diagnosis of fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease: A prospective study. | 2015 | Details |
| A19455 | 26558795 | Hepatol Int | Characterization of hepatocellular carcinoma (HCC) in non-alcoholic fatty liver disease (NAFLD) patients without cirrhosis. | 2015 | Details |
| A19456 | 26558403 | Clin Sci (Lond) | The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice. | 2015 | Details |
| A19458 | 26557954 | World J Hepatol | Histopathological differences utilizing the nonalcoholic fatty liver disease activity score criteria in diabetic (type 2 diabetes mellitus) and non-diabetic patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A19461 | 26556986 | World J Gastroenterol | Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico. | 2015 | Details |
| A19462 | 26556368 | Nutrients | Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance. | 2015 | Details |
| A19464 | 26555271 | J Hepatol | Liver Bid suppression for treatment of fibrosis associated with non-alcoholic steatohepatitis. | 2015 | Details |
| A19473 | 26539645 | Oncotarget | Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. | 2015 | Details |
| A19475 | 26537990 | Sci Rep | MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a. | 2015 | Details |
| A19478 | 26537011 | J Eur Acad Dermatol Venereol | Non-alcoholic fatty liver disease fibrosis score in patients with psoriasis. | 2015 | Details |
| A19483 | 26529285 | Biochim Biophys Acta | Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis. | 2015 | Details |