Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20808 | 25721504 | Science | Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats. | 2015 | Details |
| A20813 | 25716275 | Expert Rev Gastroenterol Hepatol | Management and diagnosis of fatty liver disease. | 2015 | Details |
| A20816 | 25714891 | Braz J Med Biol Res | Sorafenib prevents liver fibrosis in a non-alcoholic steatohepatitis (NASH) rodent model. | 2015 | Details |
| A20824 | 25711520 | Ann Transplant | The first Polish liver transplantation after Roux-en-Y gastric bypass surgery for morbid obesity: a case report and literature review. | 2015 | Details |
| A20828 | 25708897 | Dig Dis Sci | Age impacts ability of aspartate-alanine aminotransferase ratio to predict advanced fibrosis in nonalcoholic Fatty liver disease. | 2015 | Details |
| A20831 | 25708133 | Liver Int | Prevalence and risk factors for biopsy-proven non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in a prospective cohort of adult patients with gallstones. | 2015 | Details |
| A20833 | 25705637 | Ann Transl Med | Recent advances in the development of farnesoid X receptor agonists. | 2015 | Details |
| A20835 | 25703085 | J Hepatol | PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis. | 2015 | Details |
| A20837 | 25701959 | Surg Obes Relat Dis | Liver disease in the morbidly obese: a review of 1000 consecutive patients undergoing weight loss surgery. | 2014 | Details |
| A20839 | 25701721 | Eur J Pharmacol | Ipragliflozin, an SGLT2 inhibitor, exhibits a prophylactic effect on hepatic steatosis and fibrosis induced by choline-deficient l-amino acid-defined diet in rats. | 2015 | Details |
| A20841 | 25697114 | Med Hypotheses | Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. | 2015 | Details |
| A20842 | 25694178 | Expert Rev Gastroenterol Hepatol | Role of ultrasound in the diagnosis and treatment of nonalcoholic fatty liver disease and its complications. | 2015 | Details |
| A20843 | 25693058 | J Hypertens | Blood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk. | 2015 | Details |
| A20844 | 25690689 | Abdom Imaging | Ultrasound elastography: liver. | 2015 | Details |
| A20848 | 25689614 | Liver Int | Impact of skin capsular distance on the performance of controlled attenuation parameter in patients with chronic liver disease. | 2015 | Details |
| A20855 | 25684563 | J Gastroenterol Hepatol | Role of serum toll-like receptors 2 and 4 in non-alcoholic steatohepatitis and liver fibrosis. | 2015 | Details |
| A20858 | 25683343 | Diabet Med | Practical approach to non-alcoholic fatty liver disease in patients with diabetes. | 2015 | Details |
| A20861 | 25681399 | Gut | Pathobiology of liver fibrosis: a translational success story. | 2015 | Details |
| A20862 | 25681381 | Clin Infect Dis | Nonalcoholic Steatohepatitis and Hepatic Fibrosis in HIV-1-Monoinfected Adults With Elevated Aminotransferase Levels on Antiretroviral Therapy. | 2015 | Details |
| A20871 | 25672270 | Int J Mol Med | MicroRNA profiles following metformin treatment in a mouse model of non-alcoholic steatohepatitis. | 2015 | Details |
| A20884 | 25665792 | Am J Pathol | Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. | 2015 | Details |
| A20890 | 25659874 | Atheroscler Suppl | The effect of ezetimibe on NAFLD. | 2015 | Details |
| A20895 | 25657751 | J Res Med Sci | The relationship between resistin and ghrelin levels with fibrosis in nonalcoholic fatty liver disease. | 2014 | Details |
| A20899 | 25655252 | Postgrad Med J | Republished: Non-alcoholic fatty liver disease: a practical approach to treatment. | 2015 | Details |
| A20917 | 25646700 | Liver Int | Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis. | 2015 | Details |
| A20924 | 25641744 | J Gastroenterol Hepatol | PNPLA3 polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: a meta-analysis. | 2015 | Details |
| A20926 | 25637246 | Mol Genet Metab | Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans. | 2015 | Details |
| A20930 | 25633908 | Health Technol Assess | Cost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation. | 2015 | Details |
| A20931 | 25633064 | Arch Dis Child | Paediatric non-alcoholic fatty liver disease: a practical overview for non-specialists. | 2015 | Details |
| A20935 | 25632188 | World J Gastroenterol | Factors associated with significant liver fibrosis assessed using transient elastography in general population. | 2015 | Details |
| A20939 | 25629574 | Eur J Gastroenterol Hepatol | Association between liver fibrosis and coronary heart disease risk in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20940 | 25627311 | Liver Int | Fetuin-A negatively correlates with liver and vascular fibrosis in nonalcoholic fatty liver disease subjects. | 2014 | Details |
| A20943 | 25624725 | World J Gastroenterol | Association of nonalcoholic fatty liver disease and liver cancer. | 2015 | Details |
| A20944 | 25624712 | World J Gastroenterol | PNPLA3 I148M variant in nonalcoholic fatty liver disease: demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis. | 2015 | Details |
| A20948 | 25622927 | J Gastroenterol | Helicobacter pylori infection might have a potential role in hepatocyte ballooning in nonalcoholic fatty liver disease. | 2015 | Details |
| A20957 | 25617860 | Atherosclerosis | A concise review of non-alcoholic fatty liver disease. | 2015 | Details |
| A20962 | 25617409 | G3 (Bethesda) | Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet. | 2015 | Details |
| A20973 | 25609431 | FASEB J | Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. | 2015 | Details |
| A20974 | 25608776 | Ann Gastroenterol | Value of 3 Tesla diffusion-weighted magnetic resonance imaging for assessing liver fibrosis. | 2020 | Details |
| A20975 | 25607821 | Oncol Rep | Hepatic expression of the Sptlc3 subunit of serine palmitoyltransferase is associated with the development of hepatocellular carcinoma in a mouse model of nonalcoholic steatohepatitis. | 2015 | Details |
| A20978 | 25606030 | Case Rep Gastroenterol | A 25-year-old woman with type 2 diabetes and liver disease. | 2014 | Details |
| A20980 | 25605057 | Int J Mol Med | Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. | 2015 | Details |
| A20986 | 25601465 | Curr Mol Med | Understanding nutritional interventions and physical exercise in non-alcoholic fatty liver disease. | 2015 | Details |
| A20999 | 25591123 | J Pediatr Gastroenterol Nutr | Indications and limitations of bariatric intervention in severely obese children and adolescents with and without nonalcoholic steatohepatitis: ESPGHAN Hepatology Committee Position Statement. | 2015 | Details |
| A21002 | 25587525 | Pediatr Gastroenterol Hepatol Nutr | The clinical significance of serum ferritin in pediatric non-alcoholic Fatty liver disease. | 2014 | Details |
| A21003 | 25585400 | IEEE Trans Ultrason Ferroelectr Freq Control | Derivation and analysis of viscoelastic properties in human liver: impact of frequency on fibrosis and steatosis staging. | 2015 | Details |
| A21005 | 25581590 | Analyst | Vibrational signatures to discriminate liver steatosis grades. | 2015 | Details |
| A21006 | 25581573 | Liver Int | TM6SF2 E167K variant is associated with severe steatosis in chronic hepatitis C, regardless of PNPLA3 polymorphism. | 2015 | Details |
| A21011 | 25577467 | J Nutr Biochem | Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis. | 2014 | Details |
| A21015 | 25575848 | Clin J Gastroenterol | Clinical features of hepatocellular carcinoma associated with nonalcoholic fatty liver disease: a review of human studies. | 2015 | Details |
| A21016 | 25575598 | J Biol Chem | Adiponectin reduces hepatic stellate cell migration by promoting tissue inhibitor of metalloproteinase-1 (TIMP-1) secretion. | 2015 | Details |
| A21024 | 25568861 | Hepatobiliary Surg Nutr | Innate immune signaling and gut-liver interactions in non-alcoholic fatty liver disease. | 2014 | Details |
| A21025 | 25567295 | Clin Pediatr (Phila) | The full spectrum of hepatic steatosis in children. | 2015 | Details |
| A21027 | 25566193 | Front Endocrinol (Lausanne) | O-GlcNAc: A Bittersweet Switch in Liver. | 2014 | Details |
| A21028 | 25566190 | Front Endocrinol (Lausanne) | Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice. | 2014 | Details |
| A21037 | 25562616 | Endocrinology | Prevention and reversal of lipotoxicity-induced hepatic insulin resistance and steatohepatitis in mice by an antioxidant carotenoid, β-cryptoxanthin. | 2015 | Details |
| A21038 | 25562318 | J Clin Invest | Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. | 2014 | Details |
| A21041 | 25561778 | World J Gastroenterol | Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease. | 2014 | Details |
| A21047 | 25557690 | Hepatology | Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop. | 2015 | Details |
| A21050 | 25553983 | Eur J Intern Med | Prevalence of steatosis and insulin resistance in patients with chronic hepatitis B compared with chronic hepatitis C and non-alcoholic fatty liver disease. | 2014 | Details |
| A21063 | 27508191 | J Hepatocell Carcinoma | A clinical perspective of the link between metabolic syndrome and hepatocellular carcinoma. | 2015 | Details |
| A21069 | 27188459 | Nat Rev Dis Primers | Nonalcoholic fatty liver disease. | 2015 | Details |
| A21071 | 26937432 | Eur J Radiol Open | Visual assessment of biliary excretion of Gd-EOB-DTPA in patients with suspected diffuse liver disease - A biopsy-verified prospective study. | 2015 | Details |
| A21072 | 26931016 | Eksp Klin Gastroenterol | [NON-ALCOHOLIC FATTY PANCREATIC DISEASE (NAFPD) AND THE METABOLIC SYNDROME: INITIATING FACTOR OR ADDITIONAL COMPONENT?]. | 2015 | Details |
| A21078 | 25548482 | World J Gastroenterol | Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis. | 2014 | Details |
| A21081 | 25544877 | World J Hepatol | Vitamin D deficiency in chronic liver disease. | 2014 | Details |
| A21083 | 25544875 | World J Hepatol | Involvement of the TAGE-RAGE system in non-alcoholic steatohepatitis: Novel treatment strategies. | 2014 | Details |
| A21085 | 25544409 | Rev Esp Enferm Dig | Insulin resistance and metabolic syndrome are related to non-alcoholic fatty liver disease, but not visceral adiposity index, in severely obese patients. | 2014 | Details |
| A21087 | 25543522 | Clin Res Hepatol Gastroenterol | Nonalcoholic fatty liver disease (NAFLD) without insulin resistance: Is it different? | 2014 | Details |
| A21092 | 25540973 | Scand J Gastroenterol | Characterization of lean patients with nonalcoholic fatty liver disease: potential role of high hemoglobin levels. | 2014 | Details |
| A21094 | 25540086 | Dig Dis Sci | The evaluation of hepatic fibrosis scores in children with nonalcoholic fatty liver disease. | 2014 | Details |
| A21096 | 25537957 | J Gastrointest Surg | Bariatric surgery improves histological features of nonalcoholic fatty liver disease and liver fibrosis. | 2014 | Details |
| A21102 | 25535951 | PLoS One | Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology. | 2014 | Details |
| A21115 | 25532002 | J Gastrointestin Liver Dis | Non-invasive biomarkers in non-alcoholic steatohepatitis-induced hepatocellular carcinoma. | 2014 | Details |
| A21119 | 25529941 | Hepatology | Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. | 2015 | Details |
| A21130 | 25525520 | Int J Hepatol | Central portalization correlates with fibrosis but not with risk factors for nonalcoholic steatohepatitis in steatotic chronic hepatitis C. | 2014 | Details |
| A21135 | 25523099 | Exp Mol Med | Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A21142 | 25518481 | Eksp Klin Gastroenterol | [Possibilities of using the noninvasive methods of investigating the morphofunctional changes in the liver in patients with non alcoholic steatohepatitis and type 2 diabetes mellitus]. | 2014 | Details |
| A21144 | 25516385 | J Gastroenterol | The association between retinal microvascular changes, metabolic risk factors, and liver histology in pediatric patients with non-alcoholic fatty liver disease (NAFLD). | 2014 | Details |
| A21145 | 25514917 | Rev Recent Clin Trials | Non-invasive assessment of non-alcoholic fatty liver disease: ultrasound and transient elastography. | 2014 | Details |
| A21146 | 25514916 | Rev Recent Clin Trials | Non alcoholic fatty liver: epidemiology and natural history. | 2014 | Details |
| A21148 | 25514914 | Rev Recent Clin Trials | Phytotherapy and NAFLD--from goals and challenges to clinical practice. | 2014 | Details |
| A21150 | 25514912 | Rev Recent Clin Trials | Use of liver breath tests to assess severity of nonalcoholic fatty liver disease. | 2014 | Details |
| A21152 | 25514910 | Rev Recent Clin Trials | Common features of the metabolic syndrome and nonalcoholic fatty liver disease. | 2014 | Details |
| A21153 | 25514909 | Rev Recent Clin Trials | Role of adipokines and cytokines in non-alcoholic fatty liver disease. | 2014 | Details |
| A21154 | 25514908 | Rev Recent Clin Trials | The role of liver biopsy to assess non-alcoholic fatty liver disease. | 2014 | Details |
| A21155 | 25514907 | Rev Recent Clin Trials | Insulin resistance, non-alcoholic fatty liver disease and hepatitis C virus infection. | 2014 | Details |
| A21156 | 25514555 | J Hepatol | Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice. | 2014 | Details |
| A21159 | 25513983 | Menopause | Prevalence of nonalcoholic fatty liver disease and its metabolic risk factors in women of different ages and body mass index. | 2015 | Details |
| A21161 | 25512797 | World J Diabetes | Nonalcoholic steatohepatitis and insulin resistance in children. | 2014 | Details |
| A21163 | 25512222 | BMC Gastroenterol | Expression of NALPs in adipose and the fibrotic progression of non-alcoholic fatty liver disease in obese subjects. | 2014 | Details |
| A21165 | 25509904 | Ter Arkh | [[Current approaches to diagnosing and treating nonalcoholic fatty liver disease]. | 2014 | Details |
| A21167 | 25506780 | JAMA Pediatr | Nonalcoholic fatty liver disease: a challenge for pediatricians. | 2015 | Details |
| A21171 | 25502558 | PLoS One | A model of metabolic syndrome and related diseases with intestinal endotoxemia in rats fed a high fat and high sucrose diet. | 2014 | Details |
| A21172 | 25501551 | Am J Physiol Gastrointest Liver Physiol | Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. | 2014 | Details |
| A21178 | 25499943 | J Clin Lipidol | Liver histology during Mipomersen therapy for severe hypercholesterolemia. | 2014 | Details |
| A21182 | 25495478 | Liver Int | Non-invasive score system for fibrosis in chronic hepatitis: proposal for a model based on biochemical, FibroScan and ultrasound data. | 2015 | Details |
| A21183 | 25495373 | Liver Int | ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. | 2015 | Details |
| A21185 | 25493023 | World J Gastroenterol | Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease. | 2014 | Details |
| A21189 | 25492996 | World J Gastroenterol | Non-invasive diagnosis of advanced fibrosis and cirrhosis. | 2014 | Details |