Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Tumor necrosis factor1477 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17283 | 27863204 | Appl Physiol Nutr Metab | TNF and IL-18 cytokines may regulate liver fat storage under homeostasis conditions. | 2016 | Details |
| A17335 | 27836788 | Chem Biol Interact | Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage. | 2016 | Details |
| A17360 | 27824430 | Drug Res (Stuttg) | Dietary Fructose-Induced Hepatic Injury in Male and Female Rats: Influence of Resveratrol. | 2016 | Details |
| A17376 | 27818591 | World J Gastroenterol | Oral administration of a non-absorbable plant cell-expressed recombinant anti-TNF fusion protein induces immunomodulatory effects and alleviates nonalcoholic steatohepatitis. | 2016 | Details |
| A17381 | 27813270 | Mol Nutr Food Res | Endoplasmic reticulum stress contributes to ferritin molecules-mediated macrophage migration via P-selectin glycoprotein ligand-1. | 2016 | Details |
| A17406 | 27801862 | Nutrients | Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet. | 2016 | Details |
| A17428 | 27788707 | Zhonghua Gan Zang Bing Za Zhi | [Effect of JAZF1 over-expression on high-fat diet-induced non-alcoholic fatty liver disease]. | 2016 | Details |
| A17442 | 27784782 | J Biol Chem | Glucocorticoid Receptor β Induces Hepatic Steatosis by Augmenting Inflammation and Inhibition of the Peroxisome Proliferator-activated Receptor (PPAR) α. | 2016 | Details |
| A17478 | 27619543 | J Nutr Biochem | Cranberry extract attenuates hepatic inflammation in high-fat-fed obese mice. | 2016 | Details |
| A17492 | 27765368 | Phytomedicine | The chloroform extract of Cyclocarya paliurus attenuates high-fat diet induced non-alcoholic hepatic steatosis in Sprague Dawley rats. | 2016 | Details |
| A17514 | 27761469 | J Diabetes Res | Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2016 | Details |
| A17528 | 27717115 | J Sci Food Agric | Pomegranate juice prevents development of non-alcoholic fatty liver disease in rats by attenuating oxidative stress and inflammation. | 2016 | Details |
| A17536 | 27521509 | Clin Gastroenterol Hepatol | Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial. | 2016 | Details |
| A17543 | 27752155 | Beijing Da Xue Xue Bao Yi Xue Ban | [Nicotine alleviates the liver inflammation of non-alcoholic steatohepatitis induced by high-fat and high-fructose in mice]. | 2016 | Details |
| A17665 | 27678354 | World J Gastroenterol | Co-existence of non-alcoholic fatty liver disease and inflammatory bowel disease: A review article. | 2016 | Details |
| A17704 | 27646933 | Gut | Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease. | 2016 | Details |
| A17731 | 27632923 | Nutr Res | Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα. | 2016 | Details |
| A17757 | 27616896 | J Ginseng Res | Anti-inflammatory and antifatigue effect of Korean Red Ginseng in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A17826 | 27553225 | FASEB J | Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses. | 2016 | Details |
| A17850 | 27532276 | Hepatology | Novel plasma biomarkers associated with liver disease severity in adults with nonalcoholic fatty liver disease. | 2016 | Details |
| A17864 | 27514759 | Liver Int | Weight loss induced by bariatric surgery restores adipose tissue PNPLA3 expression. | 2016 | Details |
| A17889 | 27494683 | Int Immunopharmacol | High-fat diet plus carbon tetrachloride-induced liver fibrosis is alleviated by betaine treatment in rats. | 2016 | Details |
| A17922 | 27475283 | Clin Nutr | Glucose homeostasis, insulin resistance and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: Beneficial effects of supplementation with microalgae Chlorella vulgaris: A double-blind placebo-controlled randomized clinical trial. | 2016 | Details |
| A17943 | 27462372 | Diabetol Metab Syndr | Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes. | 2016 | Details |
| A17956 | 27455252 | Int J Mol Sci | Nutritional Strategies for the Individualized Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD) Based on the Nutrient-Induced Insulin Output Ratio (NIOR). | 2016 | Details |
| A18014 | 27414418 | Int J Vitam Nutr Res | Effects of Pomegranate and Orange Juice on Antioxidant Status in Non-Alcoholic Fatty Liver Disease Patients: A Randomized Clinical Trial. | 2016 | Details |
| A18045 | 27386644 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Efficacy of Zaozhu Yinchen Recipe for Treating Non-alcoholic Steatohepatitis and its Effect on Free Fatty Acid and TNF-alpha]. | 2016 | Details |
| A18064 | 27376874 | Transl Res | Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis. | 2016 | Details |
| A18081 | 27358638 | Afr Health Sci | Biochemical parameters response to weight loss in patients with non-alcoholic steatohepatitis. | 2016 | Details |
| A18097 | 27352342 | Cell Biochem Biophys | Neutrophils Play a Crucial Role in the Early Stage of Nonalcoholic Steatohepatitis via Neutrophil Elastase in Mice. | 2015 | Details |
| A18100 | 27351828 | Int Immunopharmacol | Paeoniflorin alleviates non-alcoholic steatohepatitis in rats: Involvement with the ROCK/NF-κB pathway. | 2016 | Details |
| A18108 | 27348013 | Biomolecules | Role of Transcription Factors in Steatohepatitis and Hypertension after Ethanol: The Epicenter of Metabolism. | 2016 | Details |
| A18117 | 27344153 | Biochem Genet | Evaluating -238 G>A Polymorphism Association in TNF-α Gene with Metabolic Parameters and Nutritional Intakes Among the Iranian NAFLD Patients. | 2016 | Details |
| A18118 | 27343380 | Eur J Pharmacol | (S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coagulation. | 2016 | Details |
| A18141 | 27323620 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Effect of Compound Zhajin Granule on Toll-like Receptor 4 Signaling Pathway in Nonalcoholic Steatohepatitis Mice]. | 2016 | Details |
| A18156 | 27315552 | Mol Med Rep | Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet. | 2016 | Details |
| A18225 | 27275102 | World J Gastroenterol | Serum adipokines might predict liver histology findings in non-alcoholic fatty liver disease. | 2016 | Details |
| A18229 | 27271256 | J Mol Med (Berl) | A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease. | 2016 | Details |
| A18235 | 27266339 | J Med Food | Hepatoprotective Effects of Soybean Embryo by Enhancing Adiponectin-Mediated AMP-Activated Protein Kinase α Pathway in High-Fat and High-Cholesterol Diet-Induced Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18270 | 27252817 | Middle East J Dig Dis | An Accessible and Pragmatic Experimental Model of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18318 | 27216040 | J Dig Dis | Role of intrahepatic B cells in non-alcoholic fatty liver disease by secreting pro-inflammatory cytokines and regulating intrahepatic T cells. | 2016 | Details |
| A18336 | 27197843 | Br J Nutr | Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats. | 2016 | Details |
| A18348 | 27188904 | Nutr Res | Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor κB signaling. | 2016 | Details |
| A18362 | 27181889 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Roles of MicroRNA-21 in the Pathogenesis of Insulin Resistance and Diabetic Mellitus-induced Non-alcoholic Fatty Liver Disease]. | 2016 | Details |
| A18373 | 27175704 | Medicine (Baltimore) | Accumulation of Intrahepatic TNF-α-Producing NKp44+ NK Cells Correlates With Liver Fibrosis and Viral Load in Chronic HCV Infection. | 2016 | Details |
| A18475 | 27104887 | J Physiol | Aerobic exercise training in the treatment of non-alcoholic fatty liver disease related fibrosis. | 2016 | Details |
| A18511 | 27083404 | Obes Res Clin Pract | Body mass index and the visceral adipose tissue expression of IL-6 and TNF-alpha are associated with the morphological severity of non-alcoholic fatty liver disease in individuals with class III obesity. | 2016 | Details |
| A18527 | 27069868 | Mol Metab | Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis. | 2016 | Details |
| A18615 | 27032381 | J Hepatol | Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis. | 2016 | Details |
| A18680 | 27001282 | Nutr Res | Opuntia ficus-indica seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet-fed mice. | 2015 | Details |
| A18744 | 26975539 | Metabolism | Plasma osteoprotegerin levels are inversely associated with nonalcoholic fatty liver disease in patients with type 2 diabetes: A case-control study in China. | 2015 | Details |
| A18746 | 26973390 | World J Gastroenterol | Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression. | 2016 | Details |
| A18755 | 26970305 | Biochem Biophys Res Commun | Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress. | 2016 | Details |
| A18760 | 26965314 | Lipids Health Dis | Gene polymorphisms associated with non-alcoholic fatty liver disease and coronary artery disease: a concise review. | 2016 | Details |
| A18779 | 26947067 | Cell Rep | The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction. | 2016 | Details |
| A18786 | 26942201 | Biomed Res Int | Advanced Glycation End Products Induce Obesity and Hepatosteatosis in CD-1 Wild-Type Mice. | 2016 | Details |
| A18805 | 26930651 | PLoS One | Metformin Changes the Relationship between Blood Monocyte Toll-Like Receptor 4 Levels and Nonalcoholic Fatty Liver Disease-Ex Vivo Studies. | 2016 | Details |
| A18834 | 26911834 | Sci Rep | Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis. | 2016 | Details |
| A18880 | 26889237 | Exp Ther Med | Effects of a combination of puerarin, baicalin and berberine on the expression of proliferator-activated receptor-γ and insulin receptor in a rat model of nonalcoholic fatty liver disease. | 2015 | Details |
| A18902 | 26878782 | J Nutr Biochem | A nutritional nonalcoholic steatohepatitis minipig model. | 2015 | Details |
| A18928 | 26866817 | Hepatol Res | Efficacy of probiotics in non-alcoholic fatty liver disease in adult and children: A meta-analysis of randomized controlled trials. | 2016 | Details |
| A18936 | 26860405 | J Hepatol | Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis. | 2016 | Details |
| A18964 | 26846206 | Sci Rep | Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation. | 2016 | Details |
| A18980 | 26834792 | Hepat Mon | Effects of Pentoxifylline on Non-Alcoholic Steatohepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial in Iran. | 2015 | Details |
| A19001 | 26825546 | Eur J Pharmacol | Effects of combined PPAR-γ and PPAR-α agonist therapy on fructose induced NASH in rats: Modulation of gene expression. | 2016 | Details |
| A19020 | 26817117 | Eksp Klin Gastroenterol | [COMPARISON OF DIFFERENT TREATMENT REGIMENS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE]. | 2015 | Details |
| A19036 | 26808498 | J Clin Invest | Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9. | 2016 | Details |
| A19052 | 26799523 | J Food Sci | Effects of Long-Chain and Medium-Chain Fatty Acids on Apoptosis and Oxidative Stress in Human Liver Cells with Steatosis. | 2016 | Details |
| A19085 | 26773785 | Nutr Res | Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet to induce nonalcoholic fatty liver disease. | 2015 | Details |
| A19088 | 26773297 | Hepatology | Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2016 | Details |
| A19103 | 26764184 | Gastroenterology | Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes. | 2016 | Details |
| A19117 | 26753695 | Naunyn Schmiedebergs Arch Pharmacol | Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis. | 2016 | Details |
| A19223 | 26695085 | J Gastroenterol Hepatol | Treatment with geraniol ameliorates methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in rats. | 2016 | Details |
| A19249 | 26674248 | BBA Clin | Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy. | 2015 | Details |
| A19326 | 26629094 | Int J Clin Exp Med | The effect of radish sourced 4-(Methylthio)-3-butenyl isothiocyanate on ameliorating the severity of high fat diet inducted nonalcoholic fatty liver disease in rats. | 2015 | Details |
| A19328 | 26628836 | J Clin Exp Hepatol | Remogliflozin Etabonate Improves Fatty Liver Disease in Diet-Induced Obese Male Mice. | 2015 | Details |
| A19358 | 26608915 | J Immunol | S100A8 Production in CXCR2-Expressing CD11b+Gr-1high Cells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet. | 2015 | Details |
| A19373 | 26600855 | Res Pharm Sci | Effects of rosuvastatin and/or β-carotene on non-alcoholic fatty liver in rats. | 2015 | Details |
| A19419 | 26579441 | Acta Pharm Sin B | Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism. | 2015 | Details |
| A19446 | 26566287 | PLoS One | Non-Alcoholic Fatty Liver Disease Is a Risk Factor for the Development of Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus. | 2015 | Details |
| A19493 | 26524133 | Expert Rev Gastroenterol Hepatol | The role of chronic inflammation in the development of gastrointestinal cancers: reviewing cancer prevention with natural anti-inflammatory intervention. | 2015 | Details |
| A19494 | 26523207 | World J Hepatol | Role of pentoxifylline in non-alcoholic fatty liver disease in high-fat diet-induced obesity in mice. | 2015 | Details |
| A19543 | 26498332 | Lipids Health Dis | Resveratrol ameliorates hepatic steatosis and inflammation in methionine/choline-deficient diet-induced steatohepatitis through regulating autophagy. | 2015 | Details |
| A19544 | 26498267 | Environ Toxicol Pharmacol | Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease. | 2015 | Details |
| A19580 | 26473743 | Hepatology | Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease. | 2015 | Details |
| A19589 | 26471014 | Food Funct | Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. | 2016 | Details |
| A19590 | 26469357 | Eur J Gastroenterol Hepatol | A novel model using mean platelet volume and neutrophil to lymphocyte ratio as a marker of nonalcoholic steatohepatitis in NAFLD patients: multicentric study. | 2016 | Details |
| A19594 | 26464753 | World J Hepatol | Pathogenesis of hepatocarcinogenesis in non-cirrhotic nonalcoholic fatty liver disease: Potential mechanistic pathways. | 2015 | Details |
| A19596 | 26463841 | Lipids Health Dis | Investigation into the antioxidant role of arginine in the treatment and the protection for intralipid-induced non-alcoholic steatohepatitis. | 2015 | Details |
| A19660 | 26430826 | J Am Coll Nutr | Effects of Multistrain Probiotic Supplementation on Glycemic and Inflammatory Indices in Patients with Nonalcoholic Fatty Liver Disease: A Double-Blind Randomized Clinical Trial. | 2015 | Details |
| A19675 | 26419929 | Mol Cell Endocrinol | C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress. | 2015 | Details |
| A19692 | 26407654 | Eur J Pharmacol | Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. | 2015 | Details |
| A19700 | 26405687 | Cell Mol Gastroenterol Hepatol | Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability. | 2015 | Details |
| A19715 | 26397391 | Mol Med Rep | Treatment of experimental non-alcoholic steatohepatitis by targeting α7 nicotinic acetylcholine receptor-mediated inflammatory responses in mice. | 2015 | Details |
| A19717 | 26397061 | Mol Med Rep | Therapeutic effects of the dipeptidyl peptidase-IV inhibitor, sitagliptin, on non-alcoholic steatohepatitis in FLS-ob/ob male mice. | 2015 | Details |
| A19729 | 26391864 | J Nutr Biochem | Dietary cholesterol induces hepatic inflammation and blunts mitochondrial function in the liver of high-fat-fed mice. | 2015 | Details |
| A19764 | 26367098 | Metab Syndr Relat Disord | Plasma Pentraxin 3 Differentiates Nonalcoholic Steatohepatitis (NASH) from Non-NASH. | 2015 | Details |
| A19818 | 26329041 | Cell Physiol Biochem | Ghrelin Attenuated Lipotoxicity via Autophagy Induction and Nuclear Factor-κB Inhibition. | 2015 | Details |
| A19826 | 26323153 | Zhongguo Zhong Yao Za Zhi | [Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis]. | 2015 | Details |
| A19867 | 26297911 | Biochem Pharmacol | A dipeptidyl peptidase-IV inhibitor improves hepatic steatosis and insulin resistance by AMPK-dependent and JNK-dependent inhibition of LECT2 expression. | 2015 | Details |