Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06343 | 32922061 | Clin Exp Gastroenterol | Changes in Function and Dynamics in Hepatic and Splenic Macrophages in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06344 | 32921636 | Gut Liver | Recent Epidemiology of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A06345 | 32921203 | Expert Rev Proteomics | Serum proteome assessment in nonalcoholic fatty liver disease in children: a preliminary study. | 2020 | Details |
| A06346 | 32921191 | Postgrad Med | Clinical characteristics of platelets and its possible gender dimorphism in patients with nonalcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A06347 | 32920973 | Mol Nutr Food Res | Dietary Rapeseed Oil Supplementation Reduces Hepatic Steatosis in Obese Men-A Randomized Controlled Trial. | 2020 | Details |
| A06348 | 32920226 | Redox Biol | Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis. | 2020 | Details |
| A06349 | 32920163 | Ann Hepatol | The effect of coffee consumption on the non-alcoholic fatty liver disease and liver fibrosis: A meta-analysis of 11 epidemiological studies. | 2020 | Details |
| A06350 | 32920003 | Life Sci | Hypoxia aggravates non-alcoholic fatty liver disease in presence of high fat choline deficient diet: A pilot study. | 2020 | Details |
| A06351 | 32919911 | Clin Res Hepatol Gastroenterol | Systematic review on the prevalence of nonalcoholic fatty liver disease in South Korea. | 2020 | Details |
| A06352 | 32919135 | Bioorg Chem | Design, synthesis and structure-activity relationship studies of novel partial FXR agonists for the treatment of fatty liver. | 2020 | Details |
| A06353 | 32919087 | Ann Hepatol | Diagnostic performance of three non-invasive fibrosis scores (Hepamet, FIB-4, NAFLD fibrosis score) in NAFLD patients from a mixed Latin American population. | 2020 | Details |
| A06354 | 32918763 | FASEB J | Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD. | 2020 | Details |
| A06355 | 32918742 | J Pathol | Differential TM4SF5-mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progression. | 2020 | Details |
| A06356 | 32918399 | Environ Toxicol | Sorafenib reduces steatosis-induced fibrogenesis in a human 3D co-culture model of non-alcoholic fatty liver disease. | 2020 | Details |
| A06357 | 32916992 | Molecules | LRRK2 Regulates CPT1A to Promote β-Oxidation in HepG2 Cells. | 2020 | Details |
| A06358 | 32916989 | Nutrients | Very Low-Carbohydrate Ketogenic Diet for the Treatment of Severe Obesity and Associated Non-Alcoholic Fatty Liver Disease: The Role of Sex Differences. | 2020 | Details |
| A06359 | 32916966 | Microorganisms | Disease, Drugs and Dysbiosis: Understanding Microbial Signatures in Metabolic Disease and Medical Interventions. | 2020 | Details |
| A06360 | 32916379 | Nutrition | Pleiotropic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats. | 2020 | Details |
| A06361 | 32916154 | Metabolism | Use of imaging techniques for non-invasive assessment in the diagnosis and staging of non-alcoholic fatty liver disease. | 2020 | Details |
| A06362 | 32916011 | Liver Transpl | Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. | 2020 | Details |
| A06363 | 32915852 | PLoS One | Accuracy of cytokeratin 18 (M30 and M65) in detecting non-alcoholic steatohepatitis and fibrosis: A systematic review and meta-analysis. | 2020 | Details |
| A06364 | 32914480 | Phytother Res | Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway. | 2020 | Details |
| A06365 | 32914125 | Curr Res Food Sci | Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells. | 2020 | Details |
| A06366 | 32913449 | J Cancer | Reduction of Polyunsaturated Fatty Acids with Tumor Progression in a Lean Non-Alcoholic Steatohepatitis-Associated Hepatocellular Carcinoma Mouse Model. | 2020 | Details |
| A06367 | 32912770 | Dig Liver Dis | Antidiabetic drugs and non-alcoholic fatty liver disease: A systematic review, meta-analysis and evidence map. | 2020 | Details |
| A06368 | 32910776 | Diabetes Care | Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes. | 2020 | Details |
| A06369 | 32910646 | J Med Chem | Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose. | 2020 | Details |
| A06370 | 32910431 | J Neurovirol | Direct antivirals and cognitive impairment in hepatitis C: a clinical-neurophysiologic study. | 2020 | Details |
| A06371 | 32910234 | Eur Radiol | Accuracy of controlled attenuation parameter compared with ultrasound for detecting hepatic steatosis in children with severe obesity. | 2020 | Details |
| A06372 | 32909326 | Phytother Res | Effect of sour tea supplementation on liver enzymes, lipid profile, blood pressure, and antioxidant status in patients with non-alcoholic fatty liver disease: A double-blind randomized controlled clinical trial. | 2020 | Details |
| A06373 | 32909011 | medRxiv | Non-alcoholic fatty liver disease (NAFLD) and risk of hospitalization for Covid-19. | 2020 | Details |
| A06374 | 32908830 | Eur J Case Rep Intern Med | High-Titre ANA Positivity in NAFLD: An Uncommon Presentation of a Common Disease. | 2020 | Details |
| A06375 | 32908189 | Sci Rep | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice. | 2020 | Details |
| A06376 | 32907986 | J Lipid Res | Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice. | 2020 | Details |
| A06377 | 32907904 | BMJ Open | Rationale and design of a randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated phase 2a study to investigate the efficacy and safety of elobixibat in combination with cholestyramine for non-alcoholic fatty liver disease. | 2020 | Details |
| A06378 | 32906750 | Int J Mol Sci | The Emerging Relevance of AIM2 in Liver Disease. | 2020 | Details |
| A06379 | 32906228 | Clin Mol Hepatol | Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology. | 2020 | Details |
| A06380 | 32906165 | Semin Liver Dis | Histological Endpoints for Nonalcoholic Steatohepatitis Trials: Lights and Shadows. | 2020 | Details |
| A06382 | 32905826 | Toxicology | Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro. | 2020 | Details |
| A06383 | 32903892 | Clin Exp Gastroenterol | Prevalence and Risk Factors of Hyperuricemia in Patients with Chronic Kidney Disease and Non-Alcoholic Fatty Liver. | 2020 | Details |
| A06384 | 32902660 | Abdom Radiol (NY) | Performance of morphologic criteria for the diagnosis of cirrhosis in patients with non-alcoholic steatohepatitis compared to other etiologies of chronic liver disease: effect of level of training and experience. | 2020 | Details |
| A06385 | 32900869 | mSystems | Dietary Intervention Reverses Fatty Liver and Altered Gut Microbiota during Early-Life Undernutrition. | 2020 | Details |
| A06386 | 32900489 | Biochem Biophys Res Commun | Adrenic acid induces oxidative stress in hepatocytes. | 2020 | Details |
| A06387 | 32899418 | Biomolecules | Hepatic Lipidomics and Molecular Imaging in a Murine Non-Alcoholic Fatty Liver Disease Model: Insights into Molecular Mechanisms. | 2020 | Details |
| A06388 | 32899243 | J Clin Med | Comparative Assessment and External Validation of Hepatic Steatosis Formulae in a Community-Based Setting. | 2020 | Details |
| A06389 | 32898995 | Medicine (Baltimore) | Validating candidate biomarkers for different stages of non-alcoholic fatty liver disease. | 2020 | Details |
| A06390 | 32898706 | Clin Gastroenterol Hepatol | PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06391 | 32898457 | Metab Syndr Relat Disord | Visceral Adiposity Index As a Practical Tool in Patients with Biopsy-Proven Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06392 | 32897538 | Clin Pharmacol Ther | Physiologically-Based Pharmacokinetic Model of Morphine and Morphine-3-Glucuronide in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06393 | 32897416 | Eur Radiol | Whole-liver histogram and texture analysis on T1 maps improves the risk stratification of advanced fibrosis in NAFLD. | 2020 | Details |
| A06394 | 32896622 | Biochim Biophys Acta Mol Cell Biol Lipids | 12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats. | 2020 | Details |
| A06395 | 32895402 | Sci Rep | Long-term effects of western diet consumption in male and female mice. | 2020 | Details |
| A06396 | 32894439 | Dig Dis Sci | Nonalcoholic Fatty Liver Disease Is Common in IBD Patients However Progression to Hepatic Fibrosis by Noninvasive Markers Is Rare. | 2020 | Details |
| A06397 | 32893589 | Zhongguo Zhong Yao Za Zhi | [Effect and mechanism of Bidens pilosa decoction on non-alcoholic fatty liver induced by high fat and high glucose in mice]. | 2020 | Details |
| A06398 | 32893456 | Obesity (Silver Spring) | A Fad too Far? Dietary Strategies for the Prevention and Treatment of NAFLD. | 2020 | Details |
| A06399 | 32893039 | Gastroenterol Hepatol | WITHDRAWN: Higher appendicular skeletal muscle mass percentage is an independent protective factor for non-alcoholic steatohepatitis and significant fibrosis in male with NAFLD. | 2020 | Details |
| A06400 | 32892668 | Expert Rev Gastroenterol Hepatol | Non-alcoholic fatty liver disease: molecular and cellular interplays of the lipid metabolism in a steatotic liver. | 2020 | Details |
| A06401 | 32892547 | Turk J Med Sci | Exenatide improves cardiovascular risk factors in obese patients with type 2 diabetes mellitus: a prospective study | 2021 | Details |
| A06402 | 32892401 | Scand J Immunol | Macrophages and scavenger receptors in obesity-associated non-alcoholic liver fatty disease (NAFLD). | 2020 | Details |
| A06403 | 32892365 | Aliment Pharmacol Ther | Circulating lipidomic alterations in obese and non-obese subjects with non-alcoholic fatty liver disease. | 2020 | Details |
| A06404 | 32891893 | J Nutr Biochem | Comprehensive characterization of metabolic, inflammatory and fibrotic changes in a mouse model of diet-derived nonalcoholic steatohepatitis. | 2020 | Details |
| A06405 | 32891697 | Biochimie | Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury? | 2020 | Details |
| A06408 | 32889968 | Gastroenterol Nurs | Providing Care for Fatty Liver Disease Patients: Primary Care Nurse Practitioners' Knowledge, Actions, and Preparedness. | 2021 | Details |
| A06410 | 32889748 | Biotechnol Bioeng | Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD-on-a-chip study. | 2020 | Details |
| A06411 | 32889666 | Rev Endocr Metab Disord | Hypothalamus-pituitary-adrenal Axis in Glucolipid metabolic disorders. | 2020 | Details |
| A06412 | 32888949 | Metabolism | Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice. | 2020 | Details |
| A06413 | 32888948 | Physiol Behav | The effect of aerobic, resistance, and combined training on PPAR-α, SIRT1 gene expression, and insulin resistance in high-fat diet-induced NAFLD male rats. | 2020 | Details |
| A06414 | 32888653 | Clin Radiol | Differences in multi-echo chemical shift encoded MRI proton density fat fraction estimation based on multifrequency fat peaks selection in non-alcoholic fatty liver disease patients. | 2020 | Details |
| A06415 | 32888418 | Immunity | Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver. | 2020 | Details |
| A06421 | 32885600 | Clin Obes | Bariatric surgery during the evolution of fatty liver-A randomized clinical trial comparing gastric bypass and sleeve gastrectomy based on transient elastography. | 2020 | Details |
| A06422 | 32885579 | Liver Int | Association between consumption of edible seaweeds and newly diagnosed non-alcohol fatty liver disease: The TCLSIH Cohort Study. | 2021 | Details |
| A06423 | 32885440 | J Food Sci | Effects of probiotic and prebiotic supplementation on metabolic parameters, liver aminotransferases, and systemic inflammation in nonalcoholic fatty liver disease: A randomized clinical trial. | 2020 | Details |
| A06424 | 32885245 | Am J Clin Pathol | Transcriptomic and Proteomic Analysis of Steatohepatitic Hepatocellular Carcinoma Reveals Novel Distinct Biologic Features. | 2021 | Details |
| A06425 | 32884983 | Genes Dis | Obstacles and opportunities in the prevention and treatment of HBV-related hepatocellular carcinoma. | 2020 | Details |
| A06426 | 32884949 | J Immunol Res | Kangtaizhi Granule Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats and HepG2 Cells via AMPK/mTOR Signaling Pathway. | 2020 | Details |
| A06427 | 32884438 | Yonago Acta Med | Pemafibrate Dramatically Ameliorated the Values of Liver Function Tests and Fibrosis Marker in Patients with Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06428 | 32884242 | Drug Des Devel Ther | Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy. | 2020 | Details |
| A06429 | 32883523 | Biochem Biophys Res Commun | Long-term subcutaneous injection of lipopolysaccharides and high-fat diet induced non-alcoholic fatty liver disease through IKKε/ NF-κB signaling. | 2020 | Details |
| A06430 | 32883049 | Cells | A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology. | 2020 | Details |
| A06431 | 32882815 | Children (Basel) | ALT Trends through Childhood and Adolescence Associated with Hepatic Steatosis at 24 Years: A Population-Based UK Cohort Study. | 2020 | Details |
| A06432 | 32882583 | Biomed Pharmacother | An update on β-sitosterol: A potential herbal nutraceutical for diabetic management. | 2020 | Details |
| A06433 | 32882428 | Clin Gastroenterol Hepatol | Change in MRI-PDFF and Histologic Response in Patients With Nonalcoholic Steatohepatitis: A Systematic Review and Meta-Analysis. | 2020 | Details |
| A06434 | 32882427 | Clin Gastroenterol Hepatol | Interaction Between Alcohol Consumption and PNPLA3 Variant in the Prevalence of Hepatic Steatosis in the US Population. | 2020 | Details |
| A06435 | 32882426 | Clin Gastroenterol Hepatol | Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study. | 2020 | Details |
| A06436 | 32882372 | J Hepatol | rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis. | 2020 | Details |
| A06437 | 32881925 | PLoS One | Exchanging dietary fat source with extra virgin olive oil does not prevent progression of diet-induced non-alcoholic fatty liver disease and insulin resistance. | 2020 | Details |
| A06438 | 32881371 | Pediatr Obes | Association between obstructive sleep apnea and non-alcoholic fatty liver disease in pediatric patients: a meta-analysis. | 2020 | Details |
| A06439 | 32881244 | Liver Int | A tool to predict progression of non-alcoholic fatty liver disease in severely obese patients. | 2021 | Details |
| A06440 | 32880477 | Arch Physiol Biochem | High sugar but not high fat diet consumption induces hepatic metabolic disruption and up-regulation of mitochondrial fission-associated protein Drp1 in a model of moderate obesity. | 2020 | Details |
| A06441 | 32880109 | Rev Med Suisse | [NASH: new terminology and what else is new in 2020]. | 2020 | Details |
| A06442 | 32880077 | Hepatol Int | The role of neutrophils in innate immunity-driven nonalcoholic steatohepatitis: lessons learned and future promise. | 2020 | Details |
| A06443 | 32880022 | Clin J Gastroenterol | Hepatocellular carcinoma in young morbid obese patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06444 | 32879962 | Adv Nutr | A Comprehensive Systematic Review of the Effects of Naringenin, a Citrus-Derived Flavonoid, on Risk Factors for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A06445 | 32879879 | Biomed Res Int | Endocan and Lumican in Relation to Cardiometabolic Risk in a Pediatric Overweight and Obese Cohort: A Cross-Sectional Study. | 2020 | Details |
| A06446 | 32879216 | Biol Pharm Bull | A Lipid-Based Nanocarrier Containing Active Vitamin D3 Ameliorates NASH in Mice via Direct and Intestine-Mediated Effects on Liver Inflammation. | 2020 | Details |
| A06447 | 32879136 | JCI Insight | Hepatic lipids promote liver metastasis. | 2020 | Details |
| A06448 | 32878529 | Pharm Biol | Cyclocarya paliurus extract attenuates hepatic lipid deposition in HepG2 cells by the lipophagy pathway. | 2020 | Details |
| A06449 | 32878486 | Expert Rev Gastroenterol Hepatol | Current perspectives on the pathophysiology of metabolic associated fatty liver disease: are macrophages a viable target for therapy? | 2020 | Details |
| A06450 | 32878147 | Molecules | Potential Anti-Diabetic Activity of Pueraria lobata Flower (Flos Puerariae) Extracts. | 2020 | Details |
| A06451 | 32877694 | Pharmacol Res | Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action. | 2020 | Details |