Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25226 | 22081615 | J Am Coll Nutr | Metabolic syndrome in childhood from impaired carbohydrate metabolism to nonalcoholic fatty liver disease. | 2011 | Details |
| A25227 | 22077984 | Clin Endocrinol (Oxf) | Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF-I levels. | 2012 | Details |
| A25230 | 22074433 | Curr Pharm Des | Liver enzymes: potential cardiovascular risk markers? | 2011 | Details |
| A25234 | 22067322 | Endocrinology | Prenatal dexamethasone exposure potentiates diet-induced hepatosteatosis and decreases plasma IGF-I in a sex-specific fashion. | 2011 | Details |
| A25236 | 22064361 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. | 2011 | Details |
| A25237 | 22064320 | Lab Invest | A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. | 2011 | Details |
| A25238 | 22059955 | Health Technol Assess | Insulin sensitisers in the treatment of non-alcoholic fatty liver disease: a systematic review. | 2011 | Details |
| A25240 | 22059109 | World J Hepatol | Role of ezetimibe in non-alcoholic fatty liver disease. | 2011 | Details |
| A25252 | 22043839 | Expert Opin Pharmacother | Managing the combination of nonalcoholic fatty liver disease and metabolic syndrome. | 2011 | Details |
| A25253 | 22043827 | Expert Opin Pharmacother | Statins as potential treatment for cholesterol gallstones: an attempt to understand the underlying mechanism of actions. | 2011 | Details |
| A25255 | 22030814 | Acta Cir Bras | Fructose and NAFLD: metabolic implications and models of induction in rats. | 2011 | Details |
| A25261 | 22027586 | J Hepatol | Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans. | 2011 | Details |
| A25266 | 22024495 | Nutr Res | Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight. | 2011 | Details |
| A25270 | 22023985 | J Hepatol | Omega-3 supplementation and non-alcoholic fatty liver disease: a systematic review and meta-analysis. | 2011 | Details |
| A25272 | 22020821 | Hepatol Int | Non-alcoholic fatty liver disease: is iron relevant? | 2011 | Details |
| A25275 | 22015962 | J Hepatol | A lipid to treat non-alcoholic fatty liver disease - the dawn of 'lipo-rehabilitation'? | 2011 | Details |
| A25277 | 22014765 | Diabetes Res Clin Pract | Visceral fat volume predicts new-onset type 2 diabetes in patients with chronic hepatitis C. | 2011 | Details |
| A25280 | 22013501 | World J Diabetes | MicroRNAs in hepatic pathophysiology in diabetes. | 2011 | Details |
| A25283 | 22008843 | Food Funct | The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity. | 2011 | Details |
| A25284 | 22002020 | Curr Opin Lipidol | Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic. | 2011 | Details |
| A25286 | 21999238 | J Agric Food Chem | Inhibitory effect of blueberry polyphenolic compounds on oleic acid-induced hepatic steatosis in vitro. | 2011 | Details |
| A25287 | 21994008 | Hepatology | Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. | 2012 | Details |
| A25290 | 21990953 | World J Gastroenterol | Potential risk factors for nonalcoholic steatohepatitis related to pancreatic secretions following pancreaticoduodenectomy. | 2011 | Details |
| A25291 | 21990946 | World J Gastroenterol | Betaine and nonalcoholic steatohepatitis: back to the future? | 2011 | Details |
| A25292 | 21989716 | Mol Cell Biochem | Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet. | 2011 | Details |
| A25294 | 21987620 | World J Gastroenterol | JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease. | 2011 | Details |
| A25296 | 21987488 | Hepatology | Ethnicity and nonalcoholic fatty liver disease. | 2012 | Details |
| A25297 | 21987293 | Hepatology | Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. | 2011 | Details |
| A25300 | 21986524 | Biochem Biophys Res Commun | High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis. | 2011 | Details |
| A25302 | 21985374 | Clin Exp Immunol | Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease. | 2011 | Details |
| A25305 | 21983273 | Biochim Biophys Acta | Suppression of retinol-binding protein 4 with RNA oligonucleotide prevents high-fat diet-induced metabolic syndrome and non-alcoholic fatty liver disease in mice. | 2011 | Details |
| A25312 | 21967816 | Am J Pathol | Insulin resistance and metabolic hepatocarcinogenesis with parent-of-origin effects in A×B mice. | 2011 | Details |
| A25315 | 21963564 | Biochim Biophys Acta | Liver triacylglycerol lipases. | 2011 | Details |
| A25316 | 21963507 | Biol Pharm Bull | meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells. | 2011 | Details |
| A25317 | 21962038 | BMC Public Health | Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey. | 2011 | Details |
| A25318 | 21960993 | Exp Diabetes Res | Predictors of impaired glucose regulation in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25319 | 21958877 | Eur J Pharmacol | Metformin regulates hepatic lipid metabolism through activating AMP-activated protein kinase and inducing ATGL in laying hens. | 2011 | Details |
| A25322 | 21957160 | Am J Physiol Regul Integr Comp Physiol | Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. | 2011 | Details |
| A25325 | 21954411 | World J Hepatol | Noninvasive predictors for liver fibrosis in patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A25328 | 21953137 | Dig Dis Sci | Adenovirus-36 seropositivity enhances effects of nutritional intervention on obesity, bright liver, and insulin resistance. | 2011 | Details |
| A25331 | 21952703 | Arq Gastroenterol | Gluco-lipidic indices in treated hypothyroidism associated with nonalcoholic fatty liver disease. | 2012 | Details |
| A25334 | 21951869 | Hepatol Res | Clinicopathological features of non-alcoholic fatty liver disease. | 2011 | Details |
| A25338 | 21948338 | Dig Dis Sci | Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease. | 2011 | Details |
| A25345 | 21943357 | Nutr Metab (Lond) | The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats. | 2011 | Details |
| A25350 | 21937392 | Hepatogastroenterology | The clinical significance of HbA1c as a predictive factor for abnormal postprandial glucose metabolism in NAFLD patients with an elevated liver chemistry. | 2012 | Details |
| A25352 | 21935484 | PLoS One | The in utero programming effect of increased maternal androgens and a direct fetal intervention on liver and metabolic function in adult sheep. | 2011 | Details |
| A25355 | 21932408 | Hepatology | Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. | 2011 | Details |
| A25358 | 21930939 | Proc Natl Acad Sci U S A | Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. | 2011 | Details |
| A25360 | 21929649 | J Gastroenterol Hepatol | Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. | 2012 | Details |
| A25361 | 21926952 | Minerva Ginecol | [Polycystic ovarian syndrome incidence in young women with non-alcoholic fatty liver disease]. | 2011 | Details |
| A25363 | 21918648 | Curr Gerontol Geriatr Res | Mechanisms and implications of age-related changes in the liver: nonalcoholic Fatty liver disease in the elderly. | 2011 | Details |
| A25365 | 21905818 | Int J Pediatr Obes | Fatty liver disease in obese children--relation to other metabolic risk factors. | 2011 | Details |
| A25366 | 21915061 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease is associated with blood pressure in hypertensive and nonhypertensive individuals from the general population with normal levels of alanine aminotransferase. | 2011 | Details |
| A25367 | 21913918 | Eur J Clin Invest | Characterization of nonalcoholic fatty liver disease unrelated to the metabolic syndrome. | 2011 | Details |
| A25368 | 21912741 | J Nutr Metab | Putative factors that may modulate the effect of exercise on liver fat: insights from animal studies. | 2011 | Details |
| A25369 | 21912450 | World J Gastroenterol | Pediatric nonalcoholic fatty liver disease, metabolic syndrome and cardiovascular risk. | 2011 | Details |
| A25370 | 21912108 | Ann Nutr Metab | Early-onset metabolic syndrome in prepubertal obese children and the possible role of alanine aminotransferase as marker of metabolic syndrome. | 2011 | Details |
| A25372 | 21911891 | Ann Hepatol | Plasminogen activator inhibitor type 1 serum levels and 4G/5G gene polymorphism in morbidly obese Hispanic patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25374 | 21910085 | Adv Exp Med Biol | Glycosphingolipids and insulin resistance. | 2011 | Details |
| A25376 | 21910083 | Adv Exp Med Biol | Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity. | 2011 | Details |
| A25380 | 21906580 | Am J Pathol | Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25385 | 21901256 | Dig Dis Sci | Bifidobacterium longum with fructo-oligosaccharides in patients with non alcoholic steatohepatitis. | 2011 | Details |
| A25386 | 21901160 | PLoS One | Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning. | 2011 | Details |
| A25387 | 21898634 | Ultrasound Obstet Gynecol | Ultrasonographic and laboratory markers of metabolic and cardiovascular disease risk in obese women with polycystic ovary syndrome. | 2012 | Details |
| A25392 | 21894514 | Endocrine | Non-alcoholic fatty liver disease and cardiovascular risk: metabolic aspects and novel treatments. | 2011 | Details |
| A25395 | 21894008 | Dig Dis | Obesity and fatty liver are 'grease' for the machinery of hepatic fibrosis. | 2011 | Details |
| A25396 | 21893698 | J Physiol Pharmacol | The common adiponutrin variant p.I148M does not confer gallstone risk but affects fasting glucose and triglyceride levels. | 2011 | Details |
| A25397 | 21893273 | Gastroenterol Clin North Am | Nonalcoholic fatty liver disease: pharmacologic and surgical options. | 2011 | Details |
| A25398 | 21892559 | Nutr Hosp | Molecular mechanisms of steatosis in nonalcoholic fatty liver disease. | 2012 | Details |
| A25403 | 21886908 | Sci Pharm | Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines. | 2011 | Details |
| A25410 | 21881966 | Metab Brain Dis | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. | 2011 | Details |
| A25411 | 21880110 | BJOG | A novel cause for abnormal liver function tests in pregnancy and the puerperium: non-alcoholic fatty liver disease. | 2011 | Details |
| A25418 | 21876629 | World J Gastroenterol | Nutritional recommendations for patients with non-alcoholic fatty liver diseases. | 2011 | Details |
| A25420 | 21875310 | Crit Rev Clin Lab Sci | Non-alcoholic fatty liver disease. | 2011 | Details |
| A25422 | 21873555 | FASEB J | Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet. | 2011 | Details |
| A25426 | 21862168 | Diabetes Res Clin Pract | Serum sex hormone-binding globulin levels are independently associated with nonalcoholic fatty liver disease in people with type 2 diabetes. | 2011 | Details |
| A25431 | 21853259 | Environ Health Prev Med | Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. | 2011 | Details |
| A25432 | 21853118 | PLoS One | Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. | 2011 | Details |
| A25437 | 21843565 | Arch Med Res | Treatment of atherogenic liver based on the pathogenesis of nonalcoholic fatty liver disease: a novel approach to reduce cardiovascular risk? | 2011 | Details |
| A25438 | 21841322 | Intern Med | Serum dehydroepiandrosterone sulphate levels in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25439 | 21840395 | Biochim Biophys Acta | Genetic modifiers of non-alcoholic fatty liver disease progression. | 2011 | Details |
| A25440 | 21839075 | Eur J Pharmacol | Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver. | 2011 | Details |
| A25443 | 21836057 | Am J Physiol Gastrointest Liver Physiol | Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. | 2011 | Details |
| A25450 | 21818154 | Obesity (Silver Spring) | Perinephric and epididymal fat affect hepatic metabolism in rats. | 2011 | Details |
| A25454 | 21816784 | J Clin Endocrinol Metab | Nonalcoholic fatty liver disease is associated with low circulating levels of insulin-like growth factor-I. | 2011 | Details |
| A25460 | 21808028 | Proc Natl Acad Sci U S A | Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. | 2011 | Details |
| A25468 | 21799647 | World J Gastroenterol | T1-weighted dual-echo MRI for fat quantification in pediatric nonalcoholic fatty liver disease. | 2011 | Details |
| A25469 | 21799478 | Obesity (Silver Spring) | Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. | 2011 | Details |
| A25471 | 21796479 | Endocrine | Coexistence of non-alcoholic fatty liver disease with elevated alanine aminotransferase is associated with insulin resistance in young Han males. | 2011 | Details |
| A25473 | 21794038 | Hepatol Res | Weight loss amelioration of non-alcoholic steatohepatitis linked to shifts in hepatic ceramide expression and serum ceramide levels. | 2011 | Details |
| A25475 | 21793029 | Hepatology | Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. | 2011 | Details |
| A25477 | 21790685 | Aliment Pharmacol Ther | Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25480 | 21787451 | Br J Nutr | Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice. | 2011 | Details |
| A25484 | 21778625 | Nihon Ronen Igakkai Zasshi | [Organs related to glucose metabolism and aging in animal models]. | 2011 | Details |
| A25485 | 21777557 | J Hepatol | The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver. | 2011 | Details |
| A25489 | 21773052 | J Lipids | Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation. | 2011 | Details |
| A25491 | 21770819 | Scand J Gastroenterol | Circulating vaspin and its relationship with insulin sensitivity, adiponectin, and liver histology in subjects with non-alcoholic steatohepatitis. | 2011 | Details |
| A25499 | 21765869 | Therap Adv Gastroenterol | The role of insulin-sensitizing agents in the treatment of nonalcoholic steatohepatitis. | 2011 | Details |
| A25500 | 21764575 | J Nutr Biochem | Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice. | 2011 | Details |
| A25501 | 21764273 | Nutr Metab Cardiovasc Dis | Obesity and metabolic syndrome: potential benefit from specific nutritional components. | 2011 | Details |