Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24274 | 23059407 | J Clin Gastroenterol | Primary biliary cirrhosis is more severe in overweight patients. | 2013 | Details |
| A24281 | 23042372 | Minerva Med | Circulating resistin is elevated in patients with non-alcoholic fatty liver disease and is associated with steatosis, portal inflammation, insulin resistance and nonalcoholic steatohepatitis scores. | 2012 | Details |
| A24290 | 23034128 | J Gastroenterol Hepatol | Treatment of non-alcoholic steatohepatitis with Phyllanthus urinaria: a randomized trial. | 2013 | Details |
| A24292 | 23032985 | Am J Gastroenterol | The interaction of rs738409, obesity, and alcohol: a population-based autopsy study. | 2012 | Details |
| A24294 | 23032979 | Am J Gastroenterol | Liver stiffness measurement using XL probe in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24298 | 23028442 | PLoS One | Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis. | 2012 | Details |
| A24303 | 23023916 | Magn Reson Med | In vivo (1)H-MRS hepatic lipid profiling in nonalcoholic fatty liver disease: an animal study at 9.4 T. | 2012 | Details |
| A24305 | 23022698 | Clin Gastroenterol Hepatol | Association between anthropometric parameters and measurements of liver stiffness by transient elastography. | 2012 | Details |
| A24309 | 24683373 | Gastroenterol Hepatol (N Y) | Noninvasive Diagnosis of NASH and Liver Fibrosis Within the Spectrum of NAFLD. | 2012 | Details |
| A24313 | 23012396 | Physiol Genomics | Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression. | 2012 | Details |
| A24316 | 23006461 | Saudi J Gastroenterol | Serum TGF-β, Serum MMP-1, and HOMA-IR as non-invasive predictors of fibrosis in Egyptian patients with NAFLD. | 2013 | Details |
| A24319 | 23000435 | J Hepatol | Liver transplantation for hepatocellular carcinoma in a patient with a novel telomerase mutation and steatosis. | 2012 | Details |
| A24328 | 22996622 | Hepatology | Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause? | 2013 | Details |
| A24331 | 22991207 | Physiol Genomics | Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition. | 2012 | Details |
| A24332 | 22990555 | Rom J Morphol Embryol | Association between liver histology, carotid ultrasonography and retinal vascular changes in patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24337 | 22987396 | Hepatology | Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice. | 2013 | Details |
| A24343 | 22982943 | Gastroenterology | Sterile inflammation in the liver. | 2012 | Details |
| A24345 | 22981383 | Biochem Pharmacol | Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. | 2012 | Details |
| A24355 | 22973538 | G3 (Bethesda) | Quantitative trait loci affecting liver fat content in mice. | 2012 | Details |
| A24357 | 22971072 | Hepatol Res | Association of chitotriosidase genotype with the development of non-alcoholic fatty liver disease. | 2012 | Details |
| A24358 | 22970906 | Clin Sci (Lond) | NF-κB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses. | 2013 | Details |
| A24372 | 22962039 | Pediatr Obes | Analysis of adipokine concentrations in paediatric non-alcoholic fatty liver disease. | 2012 | Details |
| A24389 | 22942630 | Int J Angiol | Carotid intima-media thickness and liver histology in hemodialysis patients with nonalcoholic Fatty liver disease. | 2011 | Details |
| A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
| A24391 | 22941015 | Recent Results Cancer Res | Surgical resection for hepatocellular carcinoma in the noncirrhotic: the Western experience. | 2013 | Details |
| A24400 | 22934189 | Int J Hepatol | Nonalcoholic Fatty liver disease in chronic hepatitis B and C patients from Western Amazon. | 2012 | Details |
| A24402 | 22934006 | Front Physiol | Liver fibrogenesis in non-alcoholic steatohepatitis. | 2012 | Details |
| A24403 | 22933860 | Gastroenterol Hepatol (N Y) | Hepatitis C virus infection and nonalcoholic steatohepatitis. | 2012 | Details |
| A24409 | 22930399 | Hepatology | Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A24410 | 22927922 | PLoS One | Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease. | 2012 | Details |
| A24411 | 22927782 | ScientificWorldJournal | The effectiveness of liraglutide in nonalcoholic fatty liver disease patients with type 2 diabetes mellitus compared to sitagliptin and pioglitazone. | 2012 | Details |
| A24414 | 22923210 | J Gastrointest Surg | Influence of hepatic parenchymal histology on outcome following right hepatic trisectionectomy. | 2012 | Details |
| A24416 | 22922372 | J Pediatr Gastroenterol Nutr | Transient elastography is a useful noninvasive tool for the evaluation of fibrosis in paediatric chronic liver disease. | 2013 | Details |
| A24420 | 22915297 | J Nutr | Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis. | 2012 | Details |
| A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
| A24431 | 22902548 | J Hepatol | Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. | 2012 | Details |
| A24432 | 22899556 | Hepatology | Determination of reliability criteria for liver stiffness evaluation by transient elastography. | 2013 | Details |
| A24441 | 22890552 | Lab Invest | Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. | 2012 | Details |
| A24444 | 22886508 | J Gastroenterol | Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis. | 2012 | Details |
| A24446 | 22884488 | Clin Biochem | Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24447 | 22884299 | Clin Res Hepatol Gastroenterol | PNPLA3, a genetic marker of progressive liver disease, still hiding its metabolic function? | 2012 | Details |
| A24455 | 22876924 | Curr Med Chem | Adiponectin: key player in the adipose tissue-liver crosstalk. | 2012 | Details |
| A24457 | 22876042 | World J Gastroenterol | Non-invasive determination of hepatic steatosis by acoustic structure quantification from ultrasound echo amplitude. | 2012 | Details |
| A24459 | 22876027 | World J Gastroenterol | Diagnostic and therapeutic implications of the association between ferritin level and severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A24465 | 22871498 | J Hepatol | Development and validation of a new histological score for pediatric non-alcoholic fatty liver disease. | 2012 | Details |
| A24466 | 22869157 | J Gastroenterol | The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis. | 2012 | Details |
| A24470 | 22864259 | Eur J Gastroenterol Hepatol | Ursodeoxycholic acid for nonalcoholic steatohepatitis. | 2012 | Details |
| A24478 | 22855443 | Dongwuxue Yanjiu | [Effects of resistin on hepatic fibrosis: possible mechanisms in non-alcoholic fatty liver disease in in vitro and in vivo]. | 2012 | Details |
| A24484 | 22848440 | PLoS One | Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24489 | 22846210 | Dis Markers | Concentrations of connective tissue growth factor in patients with nonalcoholic fatty liver disease: association with liver fibrosis. | 2012 | Details |
| A24494 | 22841522 | Metabolism | Helicobacter pylori infection in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24496 | 22840293 | Gastrointest Endosc | Intragastric balloon significantly improves nonalcoholic fatty liver disease activity score in obese patients with nonalcoholic steatohepatitis: a pilot study. | 2012 | Details |
| A24509 | 22824481 | Clin Liver Dis | Can NASH be diagnosed, graded, and staged noninvasively? | 2012 | Details |
| A24510 | 22824480 | Clin Liver Dis | Mechanisms of disease progression in NASH: new paradigms. | 2012 | Details |
| A24513 | 22824477 | Clin Liver Dis | The relevance of liver histology to predicting clinically meaningful outcomes in nonalcoholic steatohepatitis. | 2012 | Details |
| A24518 | 22820478 | J Hepatol | Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. | 2012 | Details |
| A24524 | 22809960 | Dig Liver Dis | Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance. | 2012 | Details |
| A24531 | 22796457 | Clin Gastroenterol Hepatol | Noninvasive assessment of nonalcoholic fatty liver disease in obese or overweight patients. | 2012 | Details |
| A24535 | 22795319 | Clin Res Hepatol Gastroenterol | Does fructose consumption contribute to non-alcoholic fatty liver disease? | 2012 | Details |
| A24537 | 22790906 | Dig Dis Sci | Liver stiffness measurements in patients with different stages of nonalcoholic fatty liver disease: diagnostic performance and clinicopathological correlation. | 2012 | Details |
| A24539 | 22789032 | Clin Endocrinol (Oxf) | Fatty liver and insulin resistance in children with hypobetalipoproteinemia: the importance of aetiology. | 2013 | Details |
| A24541 | 22780848 | Hepatol Res | Plasma free choline is a novel non-invasive biomarker for early-stage non-alcoholic steatohepatitis: A multi-center validation study. | 2012 | Details |
| A24545 | 22768838 | Cell Metab | Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling. | 2012 | Details |
| A24547 | 22768812 | Rev Med Inst Mex Seguro Soc | Hepatic steatosis and type 2 diabetes mellitus in health workers. | 2012 | Details |
| A24551 | 22760655 | Semin Liver Dis | Nonalcoholic fatty liver disease and HIV infection. | 2012 | Details |
| A24553 | 22753171 | Hepatology | Elovl6 promotes nonalcoholic steatohepatitis. | 2012 | Details |
| A24554 | 22753133 | Hepatology | Liver vitamin D receptor, CYP2R1, and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with nonalcoholic steatohepatitis or hepatitis C virus. | 2012 | Details |
| A24558 | 22751227 | Eur J Gastroenterol Hepatol | Etiologic types of end-stage chronic liver disease in adults: analysis of prevalence and their temporal changes from a study on native liver explants. | 2012 | Details |
| A24569 | 22740341 | Liver Transpl | Evolution of nonalcoholic fatty liver disease recurrence after liver transplantation. | 2012 | Details |
| A24571 | 22739374 | J Nutr | Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice. | 2012 | Details |
| A24575 | 22735605 | Eur J Gastroenterol Hepatol | How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A24577 | 22734967 | Clin Sci (Lond) | Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. | 2012 | Details |
| A24583 | 22724878 | Arch Iran Med | Sampling error in histopathology findings of nonalcoholic fatty liver disease: a post mortem liver histology study. | 2012 | Details |
| A24585 | 22722431 | Dig Dis | Nonalcoholic fatty liver disease/steatohepatitis: epidemiology, pathogenesis, clinical presentation and treatment. | 2012 | Details |
| A24589 | 22719876 | PLoS One | Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese. | 2012 | Details |
| A24593 | 22716237 | Histopathology | Aberrant cytokeratin 7 expression of centrilobular hepatocytes: a clinicopathological study. | 2012 | Details |
| A24594 | 22715293 | Ann Clin Biochem | The glycated albumin to glycated haemoglobin ratio increases along with the fibrosis stage in non-alcoholic steatohepatitis. | 2012 | Details |
| A24597 | 22710359 | Int J Mol Med | Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: analysis of isolated hepatic stellate cells. | 2012 | Details |
| A24598 | 22707395 | Hepatology | Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. | 2012 | Details |
| A24599 | 22707355 | Hepatology | Pioglitazone and vitamin E for nonalcoholic steatohepatitis: a cost utility analysis. | 2012 | Details |
| A24600 | 22706738 | Turk J Gastroenterol | Effects of probiotics on methionine choline deficient diet-induced steatohepatitis in rats. | 2012 | Details |
| A24605 | 22700625 | Ann Hepatol |  Gut microbiota and nonalcoholic fatty liver disease. | 2012 | Details |
| A24611 | 22692288 | Adv Anat Pathol | Liver biopsy in modern clinical practice: a pediatric point-of-view. | 2012 | Details |
| A24616 | 22688100 | Nihon Shokakibyo Gakkai Zasshi | [Validity of the NAFLD fibrosis score in a Japanese population]. | 2012 | Details |
| A24625 | 22677947 | Recenti Prog Med | [Hepatic steato-fibrosis and non-alcoholic liver disease in elderly]. | 2012 | Details |
| A24631 | 22672642 | Liver Int | Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography. | 2012 | Details |
| A24633 | 22672485 | J Am Acad Nurse Pract | Nonalcoholic fatty liver disease: the hepatic metabolic syndrome. | 2012 | Details |
| A24634 | 22672330 | Diabet Med | Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management. | 2012 | Details |
| A24635 | 22672067 | Australas J Dermatol | The increased prevalence of non-alcoholic fatty liver disease in psoriatic patients: a study from South India. | 2012 | Details |
| A24641 | 22659415 | Biochem Biophys Res Commun | GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model. | 2012 | Details |
| A24647 | 22652341 | Drug Discov Today | Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis. | 2012 | Details |
| A24652 | 22648049 | Eur Radiol | Detection of non-alcoholic steatohepatitis in patients with morbid obesity before bariatric surgery: preliminary evaluation with acoustic radiation force impulse imaging. | 2012 | Details |
| A24653 | 22646469 | Platelets | Mean platelet volume in biopsy-proven non-alcoholic fatty liver disease. | 2012 | Details |
| A24655 | 25755424 | J Clin Exp Hepatol | Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A24656 | 25755423 | J Clin Exp Hepatol | Non-invasive Diagnosis of Fibrosis in Non-alcoholic Fatty Liver Disease. | 2012 | Details |
| A24658 | 25755421 | J Clin Exp Hepatol | Non-alcoholic Fatty Liver Disease: East Versus West. | 2012 | Details |
| A24682 | 22612998 | J Hepatol | Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population. | 2012 | Details |
| A24686 | 22610002 | Clin Gastroenterol Hepatol | Prevalence and indicators of portal hypertension in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24687 | 22609320 | Eur J Radiol | Elastographic assessment of liver fibrosis in children: A prospective single center experience. | 2012 | Details |
| A24692 | 22593713 | ScientificWorldJournal | Deficiency in galectin-3 promotes hepatic injury in CDAA diet-induced nonalcoholic fatty liver disease. | 2012 | Details |