Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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lipogenesis1889 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A11372 | 30919598 | J Diabetes Investig | Rho-associated, coiled-coil-containing protein kinase 1 as a new player in the regulation of hepatic lipogenesis. | 2019 | Details |
| A11374 | 30919335 | Adv Exp Med Biol | miRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A11382 | 30918065 | J Lipid Res | PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients. | 2019 | Details |
| A11413 | 30905315 | Adipocyte | Adipocytes as lipid sensors of oleic acid transport through a functional Caco-2/HT29-MTX intestinal barrier. | 2019 | Details |
| A11422 | 30901032 | J Clin Endocrinol Metab | Dysregulation of the Splicing Machinery Is Associated to the Development of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A11423 | 30901029 | Endocr Rev | Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule. | 2019 | Details |
| A11428 | 30898698 | Gene | Long noncoding RNA Mirt2 upregulates USP10 expression to suppress hepatic steatosis by sponging miR-34a-5p. | 2019 | Details |
| A11446 | 30891617 | J Mol Med (Berl) | Innate immune regulatory networks in hepatic lipid metabolism. | 2019 | Details |
| A11464 | 30884843 | Cells | Ursodeoxycholic Acid Regulates Hepatic Energy Homeostasis and White Adipose Tissue Macrophages Polarization in Leptin-Deficiency Obese Mice. | 2019 | Details |
| A11480 | 30878016 | J Endocrinol | Short-term strength training reduces gluconeogenesis and NAFLD in obese mice. | 2019 | Details |
| A11528 | 30856468 | J Nutr Biochem | Tissue-dependent effects of cis-9,trans-11- and trans-10,cis-12-CLA isomers on glucose and lipid metabolism in adult male mice. | 2019 | Details |
| A11543 | 30850619 | Sci Rep | Voluntary exercise in mice fed an obesogenic diet alters the hepatic immune phenotype and improves metabolic parameters - an animal model of life style intervention in NAFLD. | 2019 | Details |
| A11556 | 30841536 | Int J Mol Sci | mTOR is a Key Protein Involved in the Metabolic Effects of Simple Sugars. | 2019 | Details |
| A11580 | 30832407 | Nutrients | Dietary Polyphenols Protect Against Oleic Acid-Induced Steatosis in an in Vitro Model of NAFLD by Modulating Lipid Metabolism and Improving Mitochondrial Function. | 2019 | Details |
| A11609 | 30820969 | Hepatology | Dual Specificity Phosphatase 12 Regulates Hepatic Lipid Metabolism Through Inhibition of the Lipogenesis and Apoptosis Signal-Regulating Kinase 1 Pathways. | 2019 | Details |
| A11617 | 30818824 | Nutrients | A Pathophysiological Model of Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver Slices. | 2019 | Details |
| A11635 | 30810254 | Int J Clin Pract | Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease. | 2019 | Details |
| A11657 | 30802722 | Nutr Res | Treatment with myo-inositol attenuates binding of the carbohydrate-responsive element-binding protein to the ChREBP-β and FASN genes in rat nonalcoholic fatty liver induced by high-fructose diet. | 2019 | Details |
| A11661 | 30799179 | Nutr Metab Cardiovasc Dis | Betulinic acid inhibits high-fat diet-induced obesity and improves energy balance by activating AMPK. | 2019 | Details |
| A11733 | 30772307 | EBioMedicine | Nitro-fatty acids protect against steatosis and fibrosis during development of nonalcoholic fatty liver disease in mice. | 2019 | Details |
| A11768 | 30759275 | Mol Genet Genomics | Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model. | 2019 | Details |
| A11778 | 30748020 | Hepatology | Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome Proliferator-Activated Receptor γ in Mice. | 2019 | Details |
| A11795 | 30738135 | Food Chem Toxicol | Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte. | 2019 | Details |
| A11797 | 30737251 | J Lipid Res | Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation. | 2019 | Details |
| A11801 | 30735525 | PLoS One | Epidermal growth factor receptor inhibition attenuates non-alcoholic fatty liver disease in diet-induced obese mice. | 2019 | Details |
| A11816 | 30723896 | Lipids | Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways. | 2019 | Details |
| A11819 | 30721562 | Liver Int | MicroRNA-30b regulates insulin sensitivity by targeting SERCA2b in non-alcoholic fatty liver disease. | 2019 | Details |
| A11828 | 30718741 | Sci Rep | Dietary Niacin Intake Predicts the Decrease of Liver Fat Content During a Lifestyle Intervention. | 2019 | Details |
| A11834 | 30715741 | Hepatology | Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against Palmitate Lipotoxicity. | 2019 | Details |
| A11840 | 30711569 | Metabolism | LncRNA MEG3 functions as a ceRNA in regulating hepatic lipogenesis by competitively binding to miR-21 with LRP6. | 2019 | Details |
| A11844 | 30710884 | Nutrition | No association between fruits or vegetables and non-alcoholic fatty liver disease in middle-aged men and women. | 2018 | Details |
| A11853 | 30708053 | Nanomedicine | Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis. | 2019 | Details |
| A11878 | 30700810 | Sci Rep | Depletion of B cell-activating factor attenuates hepatic fat accumulation in a murine model of nonalcoholic fatty liver disease. | 2019 | Details |
| A11881 | 34267963 | Florence Nightingale Hemsire Derg | [Is There an Effect of Dietary Fructose on Development and Prognosis of Chronic Diseases?] | 2019 | Details |
| A11895 | 30690636 | Poult Sci | Interactions between the cecal microbiota and non-alcoholic steatohepatitis using laying hens as the model. | 2019 | Details |
| A11932 | 30675881 | Food Funct | Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway. | 2019 | Details |
| A11958 | 30668424 | Phytomedicine | Lycopus lucidus Turcz. ex Benth. Attenuates free fatty acid-induced steatosis in HepG2 cells and non-alcoholic fatty liver disease in high-fat diet-induced obese mice. | 2018 | Details |
| A11959 | 30668392 | Phytomedicine | Yangonin protects against non-alcoholic fatty liver disease through farnesoid X receptor. | 2018 | Details |
| A11995 | 30653687 | Hepatology | Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Contributes to Hepatic Steatosis. | 2019 | Details |
| A12016 | 30642126 | Int J Mol Sci | Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A12030 | 30634538 | Molecules | MicroRNAs as a Novel Tool in the Diagnosis of Liver Lipid Dysregulation and Fatty Liver Disease. | 2019 | Details |
| A12036 | 30630736 | Dig Liver Dis | Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice. | 2018 | Details |
| A12054 | 30621686 | Lipids Health Dis | Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice. | 2019 | Details |
| A12069 | 30616587 | BMC Complement Altern Med | The traditional Chinese formulae Ling-gui-zhu-gan decoction alleviated non-alcoholic fatty liver disease via inhibiting PPP1R3C mediated molecules. | 2019 | Details |
| A12071 | 30615941 | Metab Eng | Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function. | 2019 | Details |
| A12078 | 30611703 | Alcohol | Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue. | 2019 | Details |
| A12093 | 30605818 | Environ Pollut | Effects of triphenyl phosphate exposure during fetal development on obesity and metabolic dysfunctions in adult mice: Impaired lipid metabolism and intestinal dysbiosis. | 2018 | Details |
| A12108 | 30599260 | Free Radic Biol Med | Loss of RIP3 initiates annihilation of high-fat diet initialized nonalcoholic hepatosteatosis: A mechanism involving Toll-like receptor 4 and oxidative stress. | 2018 | Details |
| A12114 | 30596786 | PLoS One | Protective effects of Bacillus probiotics against high-fat diet-induced metabolic disorders in mice. | 2018 | Details |
| A12131 | 30590197 | J Ethnopharmacol | Chronic treatment with the modified Longdan Xiegan Tang attenuates olanzapine-induced fatty liver in rats by regulating hepatic de novo lipogenesis and fatty acid beta-oxidation-associated gene expression mediated by SREBP-1c, PPAR-alpha and AMPK-alpha. | 2018 | Details |
| A12133 | 30589487 | Obes Rev | Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome. | 2018 | Details |
| A12141 | 30584660 | Hepatology | Arid1a Loss Drives Nonalcoholic Steatohepatitis in Mice Through Epigenetic Dysregulation of Hepatic Lipogenesis and Fatty Acid Oxidation. | 2019 | Details |
| A12143 | 30583863 | Biochem Biophys Res Commun | Erythropoietin and long-acting erythropoiesis stimulating agent ameliorate non-alcoholic fatty liver disease by increasing lipolysis and decreasing lipogenesis via EPOR/STAT pathway. | 2018 | Details |
| A12152 | 30580553 | Crit Rev Food Sci Nutr | n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. | 2018 | Details |
| A12156 | 30578967 | Biochim Biophys Acta Mol Cell Biol Lipids | Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. | 2018 | Details |
| A12165 | 30576936 | Biomed Pharmacother | Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation. | 2018 | Details |
| A12166 | 30576769 | Cell Mol Gastroenterol Hepatol | Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12195 | 30567368 | Int J Mol Sci | Effective Food Ingredients for Fatty Liver: Soy Protein β-Conglycinin and Fish Oil. | 2018 | Details |
| A12200 | 30564426 | R Soc Open Sci | Resveratrol-loaded PLGA nanoparticles: enhanced stability, solubility and bioactivity of resveratrol for non-alcoholic fatty liver disease therapy. | 2018 | Details |
| A12206 | 30562559 | Biochim Biophys Acta Mol Basis Dis | Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement of hepatic steatosis after Roux-en-Y Gastric Bypass in mice. | 2018 | Details |
| A12223 | 30556145 | Hepatology | Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12240 | 30551380 | Biomed Pharmacother | Preventive effect of trans-chalcone on non-alcoholic steatohepatitis: Improvement of hepatic lipid metabolism. | 2018 | Details |
| A12263 | 30523118 | Proc Natl Acad Sci U S A | Modulation of HIF-2α PAS-B domain contributes to physiological responses. | 2018 | Details |
| A12264 | 30522586 | J Pharm Pharm Sci | Resveratrol Limits Lipogenesis and Enhance Mitochondrial Activity in HepG2 Cells. | 2018 | Details |
| A12266 | 30541128 | J Clin Endocrinol Metab | The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet. | 2019 | Details |
| A12275 | 30537758 | Digestion | Nonalcoholic-Fatty-Liver-Disease and Nonalcoholic Steatohepatitis: Successful Development of Pharmacological Treatment Will Depend on Translational Research. | 2018 | Details |
| A12317 | 30516845 | Hepatology | Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis. | 2019 | Details |
| A12325 | 30515538 | Anal Bioanal Chem | Mapping the triglyceride distribution in NAFLD human liver by MALDI imaging mass spectrometry reveals molecular differences in micro and macro steatosis. | 2018 | Details |
| A12339 | 30500887 | Endocr Rev | Reproductive Endocrinology of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12349 | 30496542 | J Clin Endocrinol Metab | Sex Hormone-Binding Globulin Expression Correlates With Acetyl-Coenzyme A Carboxylase and Triglyceride Content in Human Liver. | 2019 | Details |
| A12363 | 30484310 | J Agric Food Chem | Folic Acid Reduced Triglycerides Deposition in Primary Chicken Hepatocytes. | 2018 | Details |
| A12374 | 30482436 | J Pharmacol Sci | Lipid-modulate activity of Cichorium glandulosum Boiss. et Huet polysaccharide in nonalcoholic fatty liver disease larval zebrafish model. | 2018 | Details |
| A12387 | 30473486 | Mol Metab | Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model. | 2018 | Details |
| A12405 | 30469030 | Redox Biol | Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes. | 2018 | Details |
| A12406 | 30468651 | Front Biosci (Landmark Ed) | Fructose at the crossroads of the metabolic syndrome and obesity epidemics. | 2019 | Details |
| A12433 | 30457067 | Proc Nutr Soc | Hepatic fatty acid synthesis and partitioning: the effect of metabolic and nutritional state. | 2018 | Details |
| A12434 | 30456918 | Diabetes Obes Metab | Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis? | 2018 | Details |
| A12437 | 30455376 | Diabetes | HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. | 2018 | Details |
| A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |
| A12517 | 30411763 | Food Funct | Hepatoprotective mechanism of freshwater clam extract alleviates non-alcoholic fatty liver disease: elucidated in vitro and in vivo models. | 2018 | Details |
| A12523 | 30411231 | J Physiol Biochem | Lipid metabolism in adipose tissue and liver from diet-induced obese rats: a comparison between Wistar and Sprague-Dawley strains. | 2018 | Details |
| A12530 | 30408433 | Toxicol Appl Pharmacol | 6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. | 2018 | Details |
| A12539 | 30402207 | Oxid Med Cell Longev | miR-26a Potentially Contributes to the Regulation of Fatty Acid and Sterol Metabolism In Vitro Human HepG2 Cell Model of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12566 | 30388740 | Nutrients | Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism. | 2018 | Details |
| A12577 | 30381838 | J Physiol | SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding. | 2018 | Details |
| A12589 | 30374109 | Sci Rep | Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism. | 2018 | Details |
| A12599 | 30368556 | Eur J Nutr | Differential capability of metabolic substrates to promote hepatocellular lipid accumulation. | 2018 | Details |
| A12615 | 30363699 | PPAR Res | Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression. | 2018 | Details |
| A12621 | 30361013 | Food Res Int | Bacupari peel extracts (Garcinia brasiliensis) reduces the biometry, lipogenesis and hepatic steatosis in obese rats. | 2018 | Details |
| A12628 | 30360437 | Int J Mol Sci | Dietary Isoliquiritigenin at a Low Dose Ameliorates Insulin Resistance and NAFLD in Diet-Induced Obesity in C57BL/6J Mice. | 2018 | Details |
| A12631 | 30359371 | PLoS One | N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice. | 2018 | Details |
| A12632 | 30359008 | J Agric Food Chem | Ursolic Acid, a Novel Liver X Receptor α (LXRα) Antagonist Inhibiting Ligand-Induced Nonalcoholic Fatty Liver and Drug-Induced Lipogenesis. | 2018 | Details |
| A12635 | 30357769 | Semin Liver Dis | Unfolded Protein Response Sensors in Hepatic Lipid Metabolism and Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12638 | 30356113 | Sci Rep | Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis. | 2018 | Details |
| A12646 | 30351048 | J Agric Food Chem | Oleanolic Acid Inhibits Liver X Receptor Alpha and Pregnane X Receptor to Attenuate Ligand-Induced Lipogenesis. | 2018 | Details |
| A12656 | 30344430 | J Ginseng Res | Ginseng seed oil ameliorates hepatic lipid accumulation in vitro and in vivo. | 2017 | Details |
| A12662 | 30340105 | Int Immunopharmacol | Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. | 2018 | Details |
| A12677 | 30333571 | Sci Rep | Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver. | 2018 | Details |
| A12684 | 30328034 | Biol Trace Elem Res | Effect of Duration of Exposure to Fluoride and Type of Diet on Lipid Parameters and De Novo Lipogenesis. | 2018 | Details |
| A12687 | 30327559 | Nat Chem Biol | Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. | 2018 | Details |