Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A49220 | 35818251 | Cell Mol Biol (Noisy-le-grand) | Effects of endoplasmic reticulum stress, liver function, insulin resistance and vascular endothelial function in patients with nonalcoholic fatty liver disease. | 2022 | Details |
| A49223 | 35817047 | Exp Clin Endocrinol Diabetes | Comorbidities in Mild Autonomous Cortisol Secretion - A Clinical Review of Literature. | 2022 | Details |
| A49226 | 35816139 | J Sports Med Phys Fitness | The effect of aerobic exercise on metabolic parameters of patients with non-alcoholic fatty liver disease: systematic review and meta-analysis. | 2022 | Details |
| A49228 | 35814521 | J Clin Exp Hepatol | Quantitative Ultrasound Assessment of Hepatic Steatosis. | 2022 | Details |
| A49243 | 35811725 | Front Cardiovasc Med | Glycation and a Spark of ALEs (Advanced Lipoxidation End Products) - Igniting RAGE/Diaphanous-1 and Cardiometabolic Disease. | 2022 | Details |
| A49262 | 35806934 | J Clin Med | The Role of Insulin Resistance in Fueling NAFLD Pathogenesis: From Molecular Mechanisms to Clinical Implications. | 2022 | Details |
| A49271 | 35806010 | Int J Mol Sci | MAFLD and CKD: An Updated Narrative Review. | 2022 | Details |
| A49288 | 35799081 | Pharm Res | Lipocalin-Type Prostaglandin D2 Synthase Protein- A Central Player in Metabolism. | 2022 | Details |
| A49325 | 35788089 | Chin Med J (Engl) | Bile acids and sphingolipids in non-alcoholic fatty liver disease. | 2022 | Details |
| A49332 | 35785498 | Phytother Res | Effects of licorice root supplementation on liver enzymes, hepatic steatosis, metabolic and oxidative stress parameters in women with nonalcoholic fatty liver disease: A randomized double-blind clinical trial. | 2022 | Details |
| A49336 | 35784568 | Front Endocrinol (Lausanne) | Multi-Faceted Influence of Obesity on Type 1 Diabetes in Children - From Disease Pathogenesis to Complications. | 2022 | Details |
| A49337 | 35784557 | Front Endocrinol (Lausanne) | Effects of Bariatric Endoscopy on Non-Alcoholic Fatty Liver Disease: A Comprehensive Systematic Review and Meta-Analysis. | 2022 | Details |
| A49338 | 35784533 | Front Endocrinol (Lausanne) | Fufang Zhenzhu Tiaozhi Capsule Prevents Intestinal Inflammation and Barrier Disruption in Mice With Non-Alcoholic Steatohepatitis. | 2022 | Details |
| A49340 | 35783879 | Cureus | Nonalcoholic Fatty Liver Disease: An Emerging Modern-Day Risk Factor for Cardiovascular Disease. | 2022 | Details |
| A49346 | 35782914 | Front Nutr | The Human Milk Oligosaccharide 2'-Fucosyllactose Alleviates Liver Steatosis, ER Stress and Insulin Resistance by Reducing Hepatic Diacylglycerols and Improved Gut Permeability in Obese Ldlr-/-.Leiden Mice. | 2022 | Details |
| A49348 | 35782337 | Gastroenterol Res Pract | Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49352 | 35780841 | Life Sci | Ellagic acid ameliorates high fructose-induced hyperuricemia and non-alcoholic fatty liver in Wistar rats: Focusing on the role of C1q/tumor necrosis factor-related protein-3 and ATP citrate lyase. | 2022 | Details |
| A49359 | 35779187 | Cell Stress Chaperones | Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. | 2022 | Details |
| A49360 | 35778847 | Lipids | Structurally-engineered fatty acid 1024 (SEFA-1024) improves diet-induced obesity, insulin resistance, and fatty liver disease. | 2022 | Details |
| A49361 | 35778734 | Cardiovasc Diabetol | TyG index is positively associated with risk of CHD and coronary atherosclerosis severity among NAFLD patients. | 2022 | Details |
| A49366 | 35777449 | Biochem Pharmacol | Ceramide de novo synthesis in non-alcoholic fatty liver disease: Pathogenic mechanisms and therapeutic perspectives. | 2022 | Details |
| A49369 | 35773644 | BMC Gastroenterol | Evaluating future risk of NAFLD in adolescents: a prediction and decision curve analysis. | 2022 | Details |
| A49387 | 35766833 | Compr Physiol | Paying the Iron Price: Liver Iron Homeostasis and Metabolic Disease. | 2022 | Details |
| A49395 | 35765060 | Cell Biosci | Novel insights into non-alcoholic fatty liver disease and dementia: insulin resistance, hyperammonemia, gut dysbiosis, vascular impairment, and inflammation. | 2022 | Details |
| A49399 | 35764198 | J Ethnopharmacol | Exploring therapeutic mechanisms of San-Huang-Tang in nonalcoholic fatty liver disease through network pharmacology and experimental validation. | 2022 | Details |
| A49403 | 35762159 | Curr Opin Clin Nutr Metab Care | Intrahepatic triglyceride content: influence of metabolic and genetics drivers. | 2022 | Details |
| A49404 | 35761888 | Diabetes Metab Syndr Obes | Risk Factors for Nonalcoholic Fatty Liver Disease in Postmenopausal Women with Type 2 Diabetes Mellitus and the Correlation with Bone Mineral Density at Different Locations. | 2022 | Details |
| A49409 | 35760093 | Life Sci | The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions. | 2022 | Details |
| A49418 | 35757255 | Front Nutr | Curcuminoids for Metabolic Syndrome: Meta-Analysis Evidences Toward Personalized Prevention and Treatment Management. | 2022 | Details |
| A49423 | 35755273 | Acta Pharm Sin B | Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy-lysosomal pathway. | 2021 | Details |
| A49442 | 35748302 | J Gastroenterol Hepatol | Circulating adiponectin in patients with nonalcoholic fatty liver disease-related liver fibrosis: a systematic review and a meta-analysis. | 2022 | Details |
| A49460 | 35744822 | Molecules | Neuroendocrine-Immune Regulatory Network of Eucommia ulmoides Oliver. | 2022 | Details |
| A49464 | 35744024 | Medicina (Kaunas) | An Update on the Chemokine System in the Development of NAFLD. | 2022 | Details |
| A49468 | 35743545 | J Clin Med | Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49469 | 35743358 | J Clin Med | When Sugar Reaches the Liver: Phenotypes of Patients with Diabetes and NAFLD. | 2022 | Details |
| A49471 | 35743232 | Int J Mol Sci | SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway. | 2022 | Details |
| A49478 | 35740464 | Biomedicines | The Emerging Role of Branched-Chain Amino Acids in Liver Diseases. | 2022 | Details |
| A49479 | 35740337 | Biomedicines | Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology. | 2022 | Details |
| A49484 | 35740245 | Biomedicines | Mechanisms Underlying Antipsychotic-Induced NAFLD and Iron Dysregulation: A Multi-Omic Approach. | 2022 | Details |
| A49486 | 35740032 | Antioxidants (Basel) | NADPH Oxidases Connecting Fatty Liver Disease, Insulin Resistance and Type 2 Diabetes: Current Knowledge and Therapeutic Outlook. | 2022 | Details |
| A49493 | 35738176 | Biomed Pharmacother | Sex hormone binding globulin as a potential drug candidate for liver-related metabolic disorders treatment. | 2022 | Details |
| A49498 | 35736186 | Mar Drugs | Marine Chitooligosaccharide Alters Intestinal Flora Structure and Regulates Hepatic Inflammatory Response to Influence Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49517 | 35728960 | Cas Lek Cesk | Metabolic dysfunction-associated fatty liver disease (MAFLD) as a more accurate name for NAFLD - common aspects of pathogenesis. | 2022 | Details |
| A49520 | 35728768 | Free Radic Biol Med | Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2. | 2022 | Details |
| A49524 | 35726797 | Food Funct | Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats. | 2022 | Details |
| A49527 | 35726152 | Endocrinol Metab (Seoul) | The Impact of Insulin Resistance on Hepatic Fibrosis among United States Adults with Non-Alcoholic Fatty Liver Disease: NHANES 2017 to 2018. | 2022 | Details |
| A49530 | 35724509 | Biomed Pharmacother | Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics. | 2022 | Details |
| A49534 | 35723052 | Food Funct | Coffee peel extracts ameliorate non-alcoholic fatty liver disease via a fibroblast growth factor 21-adiponectin signaling pathway. | 2022 | Details |
| A49540 | 35721171 | Front Pharmacol | Protective Effects and Mechanisms of Yinchen Linggui Zhugan Decoction in HFD-Induced Nonalcoholic Fatty Liver Disease Rats Based on Network Pharmacology and Experimental Verification. | 2022 | Details |
| A49550 | 35718058 | Am J Pathol | Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice. | 2022 | Details |
| A49558 | 35714570 | Biochem Biophys Res Commun | TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells. | 2022 | Details |
| A49559 | 35713877 | Diabetes | Hyperinsulinemia is Highly Associated with Markers of Hepatocytic Senescence in Two Independent Cohorts. | 2022 | Details |
| A49561 | 35713614 | Lab Med | Association of rs5742612 Polymorphism in the Promoter Region of IGF1 Gene with Nonalcoholic Fatty Liver Disease: A Case-Control Study. | 2022 | Details |
| A49568 | 35710164 | Scand J Gastroenterol | The effect of a fruit-rich diet on liver biomarkers, insulin resistance, and lipid profile in patients with non-alcoholic fatty liver disease: a randomized clinical trial. | 2022 | Details |
| A49577 | 35708630 | J Med Food | Nil-Surin Rice Bran Hydrolysates Improve Lipid Metabolism and Hepatic Steatosis by Regulating Secretion of Adipokines and Expression of Lipid-Metabolism Genes. | 2022 | Details |
| A49587 | 35702836 | J Assoc Physicians India | Interrelation of the Risk Factors of NAFLD at various Stages of Progression of the glycemic Status on long-term Follow-up. | 2022 | Details |
| A49588 | 35702577 | Intractable Rare Dis Res | Diagnosing Alström syndrome in a patient followed up with syndromic obesity for years. | 2022 | Details |
| A49606 | 35693397 | Hepatobiliary Surg Nutr | Extrahepatic organs in the development of non-alcoholic fatty liver disease in liver transplant patients. | 2022 | Details |
| A49629 | 35685554 | Int J Clin Pract | The Gut-Liver Axis in Nonalcoholic Fatty Liver Disease: Association of Intestinal Permeability with Disease Severity and Treatment Outcomes. | 2022 | Details |
| A49632 | 35684158 | Nutrients | 11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway. | 2022 | Details |
| A49639 | 35683431 | J Clin Med | Triglyceride and Glucose Index as a Screening Tool for Nonalcoholic Liver Disease in Patients with Metabolic Syndrome. | 2022 | Details |
| A49640 | 35682957 | Int J Mol Sci | Smad3 Phospho-Isoform Signaling in Nonalcoholic Steatohepatitis. | 2022 | Details |
| A49648 | 35680169 | Clin Mol Hepatol | The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults. | 2022 | Details |
| A49665 | 35677177 | Comput Math Methods Med | Effect of Probiotics Therapy on Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49668 | 35676065 | Magn Reson Med Sci | The Accuracy and Clinical Relevance of the Multi-echo Dixon Technique for Evaluating Changes to Hepatic Steatosis in Patients with Non-alcoholic Fatty Liver Disease Treated with Formulated Food. | 2022 | Details |
| A49669 | 35675800 | Cell Metab | Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia. | 2022 | Details |
| A49672 | 35674697 | Obesity (Silver Spring) | Triglyceride and glucose index is a simple and easy-to-calculate marker associated with nonalcoholic fatty liver disease. | 2022 | Details |
| A49677 | 35673435 | J Diabetes Metab Disord | The triglyceride-glucose index as a clinical useful marker for metabolic associated fatty liver disease (MAFLD): a population-based study among Iranian adults. | 2022 | Details |
| A49679 | 35672633 | Environ Sci Pollut Res Int | Microarray analysis of mRNA expression profiles in liver of ob/ob mice with real-time atmospheric PM2.5 exposure. | 2022 | Details |
| A49680 | 35672623 | Dig Dis Sci | Histologic Severity of Nonalcoholic Fatty Liver Disease Associates with Reduced Bone Mineral Density in Children. | 2022 | Details |
| A49685 | 35671811 | Life Sci | Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades. | 2022 | Details |
| A49690 | 35669067 | Front Nutr | Effects of Synbiotics, Probiotics, and Prebiotics on Liver Enzymes of Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis. | 2022 | Details |
| A49693 | 35668285 | Hepatol Int | Chronic intermittent hypoxia contributes to non-alcoholic steatohepatitis progression in patients with obesity. | 2022 | Details |
| A49694 | 35667460 | Int J Biol Macromol | Chondroitin sulfate stimulates the secretion of H2S by Desulfovibrio to improve insulin sensitivity in NAFLD mice. | 2022 | Details |
| A49698 | 35665440 | J Cell Mol Med | Mechanisms of Gynostemma pentaphyllum against non-alcoholic fibre liver disease based on network pharmacology and molecular docking. | 2022 | Details |
| A49703 | 35664038 | World J Gastroenterol | Mechanisms of ductular reaction in non-alcoholic steatohepatitis. | 2022 | Details |
| A49704 | 35663787 | Int J Pediatr Adolesc Med | Treatment of hyperglycemia not associated with NAFLD improvement in children with type 2 diabetes mellitus. | 2021 | Details |
| A49709 | 35662921 | Front Nutr | High Protein Diets Improve Liver Fat and Insulin Sensitivity by Prandial but Not Fasting Glucagon Secretion in Type 2 Diabetes. | 2022 | Details |
| A49719 | 35659558 | BMC Cardiovasc Disord | The correlation of atherosclerosis and triglyceride glucose index: a secondary analysis of a national cross-sectional study of Japanese. | 2022 | Details |
| A49738 | 35654225 | Mol Cell Endocrinol | Treatment with spexin mitigates diet-induced hepatic steatosis in vivo and in vitro through activation of galanin receptor 2. | 2022 | Details |
| A49739 | 35654114 | Metabolism | GW9662, a peroxisome proliferator-activated receptor gamma antagonist, attenuates the development of non-alcoholic fatty liver disease. | 2022 | Details |
| A49743 | 35651973 | Front Endocrinol (Lausanne) | Contribution of Liver and Pancreatic Islet Crosstalk to β-Cell Function/Dysfunction in the Presence of Fatty Liver. | 2022 | Details |
| A49748 | 35650449 | Pharm Res | Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review. | 2022 | Details |
| A49754 | 35646540 | Acta Pharm Sin B | Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases. | 2021 | Details |
| A49756 | 35646271 | World J Hepatol | Testosterone therapy reduces hepatic steatosis in men with type 2 diabetes and low serum testosterone concentrations. | 2022 | Details |
| A49767 | 35643859 | Lab Invest | A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis. | 2022 | Details |
| A49775 | 35642168 | Sichuan Da Xue Xue Bao Yi Xue Ban | [Research Progress in High-Sugar Diet and Inflammatory Diseases]. | 2022 | Details |
| A49778 | 35640037 | Hum Reprod | Comparison of the cardiometabolic profiles of adolescents conceived through ART with those of a non-ART cohort. | 2022 | Details |
| A49779 | 35639744 | PLoS One | A significant risk of metabolic dysfunction-associated fatty liver disease plus diabetes on subclinical atherosclerosis. | 2022 | Details |
| A49783 | 35639037 | J Physiol Pharmacol | Are insulin resistance and non-alcoholic fatty liver disease associated with Peyronie's disease? A pilot study. | 2022 | Details |
| A49792 | 35636169 | Phytomedicine | Pharmacological effects of polydatin in the treatment of metabolic diseases: A review. | 2022 | Details |
| A49798 | 35634707 | Gut Microbes | Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis. | 2022 | Details |
| A49800 | 35634340 | Front Immunol | The Potential Role of Gut Microbial-Derived Exosomes in Metabolic-Associated Fatty Liver Disease: Implications for Treatment. | 2022 | Details |
| A49810 | 35630058 | Medicina (Kaunas) | Chronic Inflammation-A Link between Nonalcoholic Fatty Liver Disease (NAFLD) and Dysfunctional Adipose Tissue. | 2022 | Details |
| A49812 | 35629938 | Metabolites | Individuals with Metabolic Syndrome Show Altered Fecal Lipidomic Profiles with No Signs of Intestinal Inflammation or Increased Intestinal Permeability. | 2022 | Details |
| A49813 | 35629915 | Metabolites | Renin-Angiotensin System in Liver Metabolism: Gender Differences and Role of Incretins. | 2022 | Details |
| A49825 | 35626354 | Diagnostics (Basel) | Characteristics of Urine Organic Acid Metabolites in Nonalcoholic Fatty Liver Disease Assessed Using Magnetic Resonance Imaging with Elastography in Korean Adults. | 2022 | Details |
| A49828 | 35625920 | Biomedicines | Premenopausal Syndrome and NAFLD: A New Approach Based on Gender Medicine. | 2022 | Details |
| A49838 | 35624769 | Antioxidants (Basel) | Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A49867 | 35614469 | Cardiovasc Diabetol | The current role of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus management. | 2022 | Details |