Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24365 | 22964849 | Lab Invest | Stimulation of fat accumulation in hepatocytes by PGE₂-dependent repression of hepatic lipolysis, β-oxidation and VLDL-synthesis. | 2012 | Details |
| A24366 | 22964732 | Ann Surg | Liver transplantation for nonalcoholic steatohepatitis: the new epidemic. | 2012 | Details |
| A24368 | 22964626 | Digestion | High prevalence of gastroesophageal reflux symptoms in patients with non-alcoholic fatty liver disease associated with serum levels of triglyceride and cholesterol but not simple visceral obesity. | 2012 | Details |
| A24369 | 22963909 | Dig Liver Dis | Non-alcoholic fatty liver disease is associated with high prevalence of gastro-oesophageal reflux symptoms. | 2012 | Details |
| A24374 | 22960889 | Indian J Med Res | Association of pro-inflammatory cytokines, adipokines & oxidative stress with insulin resistance & non-alcoholic fatty liver disease. | 2012 | Details |
| A24376 | 22959976 | Arch Med Res | Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population. | 2012 | Details |
| A24377 | 22959662 | Atherosclerosis | Liver fat content is associated with an increase in cholesterol synthesis independent of statin therapy use in patients with type 2 diabetes. | 2012 | Details |
| A24379 | 22955994 | Diabetologia | Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance. | 2012 | Details |
| A24384 | 22950794 | Nucleic Acid Ther | Role of regulatory micro RNAs in type 2 diabetes mellitus-related inflammation. | 2012 | Details |
| A24385 | 22950627 | Scand J Clin Lab Invest | A novel appetite peptide, nesfatin-1 in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24388 | 22949106 | Curr Atheroscler Rep | Fructose and risk of cardiometabolic disease. | 2012 | Details |
| A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
| A24393 | 22940046 | J Hepatol | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. | 2012 | Details |
| A24398 | 22935341 | Nutr Res | The lipid accumulation product is highly related to serum alanine aminotransferase level in male adults. | 2012 | Details |
| A24401 | 22934096 | Front Immunol | Resolution of inflammation in obesity-induced liver disease. | 2012 | Details |
| A24403 | 22933860 | Gastroenterol Hepatol (N Y) | Hepatitis C virus infection and nonalcoholic steatohepatitis. | 2012 | Details |
| A24405 | 22932913 | Horm Metab Res | Reversion of steatosis by SREBP-1c antisense oligonucleotide did not improve hepatic insulin action in diet-induced obesity mice. | 2012 | Details |
| A24406 | 22932160 | Eur J Gastroenterol Hepatol | Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents. | 2012 | Details |
| A24407 | 22931359 | Disabil Rehabil | Comparison of activity level among patients with chronic liver disease. | 2012 | Details |
| A24412 | 22925921 | J Pediatr Gastroenterol Nutr | Psychosocial outcomes for children with nonalcoholic fatty liver disease over time and compared with obese controls. | 2013 | Details |
| A24413 | 22923371 | Lipids | Dietary trans-fatty acid induced NASH is normalized following loss of trans-fatty acids from hepatic lipid pools. | 2012 | Details |
| A24419 | 22918684 | Dig Dis Sci | Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis. | 2012 | Details |
| A24422 | 22913901 | Postgrad Med | Managing diabetes in patients with chronic liver disease. | 2012 | Details |
| A24426 | 22908056 | Hormones (Athens) | The pluses and minuses of bariatric surgery for morbid obesity: An endocrinological perspective. | 2013 | Details |
| A24428 | 22903720 | Methods Mol Biol | Proteomics analysis of human nonalcoholic fatty liver. | 2012 | Details |
| A24430 | 22902550 | J Hepatol | miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. | 2012 | Details |
| A24434 | 22899407 | Georgian Med News | [Treatment of nonalcogolic fatty disease of liver]. | 2012 | Details |
| A24435 | 22899406 | Georgian Med News | [Peculiarities of metabolic syndrome and nonalcogolic fatty liver disease in menopausal women]. | 2012 | Details |
| A24436 | 22898488 | BMC Gastroenterol | The I148M PNPLA3 polymorphism influences serum adiponectin in patients with fatty liver and healthy controls. | 2012 | Details |
| A24437 | 22898281 | Zhongguo Dang Dai Er Ke Za Zhi | [Quantitative assessment of intrahepatic fat content in children and adolescents with non-alcoholic fatty liver disease]. | 2012 | Details |
| A24438 | 22893453 | Endocr J | Fatty liver as a consequence and cause of insulin resistance: lessons from type 2 diabetic liver. | 2012 | Details |
| A24440 | 22891896 | Appl Physiol Nutr Metab | Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction. | 2012 | Details |
| A24447 | 22884299 | Clin Res Hepatol Gastroenterol | PNPLA3, a genetic marker of progressive liver disease, still hiding its metabolic function? | 2012 | Details |
| A24450 | 22882200 | HPB (Oxford) | Equivalent survival following liver transplantation in patients with non-alcoholic steatohepatitis compared with patients with other liver diseases. | 2012 | Details |
| A24455 | 22876924 | Curr Med Chem | Adiponectin: key player in the adipose tissue-liver crosstalk. | 2012 | Details |
| A24458 | 22876038 | World J Gastroenterol | Moro orange juice prevents fatty liver in mice. | 2012 | Details |
| A24460 | 22876026 | World J Gastroenterol | Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome. | 2012 | Details |
| A24461 | 22875138 | Pediatr Cardiol | The relationship between pediatric nonalcoholic fatty liver disease and cardiovascular risk factors and increased risk of atherosclerosis in obese children. | 2012 | Details |
| A24477 | 22855696 | World J Hepatol | Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24481 | 22851489 | J Clin Endocrinol Metab | Increased tenascin C and Toll-like receptor 4 levels in visceral adipose tissue as a link between inflammation and extracellular matrix remodeling in obesity. | 2012 | Details |
| A24484 | 22848440 | PLoS One | Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24486 | 22846856 | Semin Oncol | Causes of and prevention strategies for hepatocellular carcinoma. | 2012 | Details |
| A24488 | 22846254 | Digestion | Liver transplantation in nonalcoholic steatohepatitis is associated with high mortality and post-transplant complications: a single-center experience. | 2012 | Details |
| A24493 | 22841818 | Am J Pathol | Therapeutic administration of the direct thrombin inhibitor argatroban reduces hepatic inflammation in mice with established fatty liver disease. | 2012 | Details |
| A24496 | 22840293 | Gastrointest Endosc | Intragastric balloon significantly improves nonalcoholic fatty liver disease activity score in obese patients with nonalcoholic steatohepatitis: a pilot study. | 2012 | Details |
| A24498 | 22837189 | J Clin Endocrinol Metab | Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance. | 2012 | Details |
| A24503 | 22826613 | World J Gastroenterol | Multicausality in fatty liver disease: is there a rationale to distinguish between alcoholic and non-alcoholic origin? | 2012 | Details |
| A24505 | 22824485 | Clin Liver Dis | Management of nonalcoholic steatohepatitis: an evidence-based approach. | 2012 | Details |
| A24506 | 22824484 | Clin Liver Dis | Psychological and psychiatric aspects of treatment of obesity and nonalcoholic fatty liver disease. | 2012 | Details |
| A24516 | 22821716 | Liver Transpl | Reducing the load: the evolution and management of obesity and nonalcoholic steatohepatitis before liver transplantation. | 2012 | Details |
| A24518 | 22820478 | J Hepatol | Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. | 2012 | Details |
| A24519 | 22819913 | Hepatogastroenterology | Roles of hepatic progenitor cells activation, ductular reaction proliferation and Notch signaling in morbid obesity. | 2012 | Details |
| A24525 | 22809102 | Annu Rev Nutr | Endoplasmic reticulum stress in nonalcoholic fatty liver disease. | 2012 | Details |
| A24526 | 22808787 | Eksp Klin Gastroenterol | [Nutrition mistakes in patients with nonalcoholic fatty liver disease and the ways of correction]. | 2012 | Details |
| A24527 | 22807031 | Diabetes | Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. | 2012 | Details |
| A24528 | 22806626 | Hepatology | Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia. | 2012 | Details |
| A24531 | 22796457 | Clin Gastroenterol Hepatol | Noninvasive assessment of nonalcoholic fatty liver disease in obese or overweight patients. | 2012 | Details |
| A24532 | 22796347 | Nutr Metab Cardiovasc Dis | Ambulatory arterial stiffness indices and non-alcoholic fatty liver disease in essential hypertension. | 2012 | Details |
| A24535 | 22795319 | Clin Res Hepatol Gastroenterol | Does fructose consumption contribute to non-alcoholic fatty liver disease? | 2012 | Details |
| A24538 | 22790124 | Intern Med | Non-alcoholic fatty liver disease is an independent predictor for macroangiopathy in Japanese type 2 diabetic patients: a cross-sectional study. | 2012 | Details |
| A24540 | 22788090 | Rom J Intern Med | Non-alcoholic fatty liver disease and the statins treatment. | 2012 | Details |
| A24545 | 22768838 | Cell Metab | Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling. | 2012 | Details |
| A24546 | 22768831 | Cell Metab | Leptin in the liver: a toxic or beneficial mix? | 2012 | Details |
| A24548 | 22768070 | PLoS One | Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice. | 2012 | Details |
| A24552 | 22760235 | JAMA | Management of nonalcoholic fatty liver disease: a 60-year-old man with probable nonalcoholic fatty liver disease: weight reduction, liver biopsy, or both? | 2012 | Details |
| A24553 | 22753171 | Hepatology | Elovl6 promotes nonalcoholic steatohepatitis. | 2012 | Details |
| A24555 | 22751848 | Int J Mol Med | Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis. | 2012 | Details |
| A24556 | 22751700 | Diabetes | Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. | 2012 | Details |
| A24557 | 22751691 | Diabetes | Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. | 2012 | Details |
| A24562 | 22749135 | J Nutr Biochem | The role of dietary fatty acids in the pathology of metabolic syndrome. | 2012 | Details |
| A24563 | 22748277 | Atherosclerosis | Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in Asian Indians. | 2012 | Details |
| A24564 | 22746301 | Curr Drug Metab | Drug disposition in pathophysiological conditions. | 2012 | Details |
| A24567 | 22742899 | Eur J Pharmacol | Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. | 2012 | Details |
| A24568 | 22741595 | J Gastroenterol Hepatol | Prevalence and risk factors for non-alcoholic fatty liver disease in Asian people who are not obese. | 2012 | Details |
| A24571 | 22739374 | J Nutr | Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice. | 2012 | Details |
| A24574 | 22735606 | Eur J Gastroenterol Hepatol | The alanine aminotransferase to triglycerides ratio as a marker to identify nonalcoholic fatty liver disease. | 2012 | Details |
| A24575 | 22735605 | Eur J Gastroenterol Hepatol | How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A24576 | 22735219 | Rev Assoc Med Bras (1992) | Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals. | 2013 | Details |
| A24582 | 22728333 | J Endocrinol | β(1) Adrenergic receptor is key to cold- and diet-induced thermogenesis in mice. | 2012 | Details |
| A24584 | 22722986 | Indian J Pediatr | Fatty liver disease in children--what should one do? | 2012 | Details |
| A24586 | 22720311 | J Gastrointestin Liver Dis | Is visceral fat reduction necessary to favour metabolic changes in the liver? | 2012 | Details |
| A24588 | 22720061 | PLoS One | Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice. | 2012 | Details |
| A24591 | 22717644 | Endocrinol Nutr | [Non-alcoholic fatty liver disease and its association with clinical and biochemical variables in obese children and adolescents: effect of a one-year intervention on lifestyle]. | 2012 | Details |
| A24592 | 22717200 | J Acad Nutr Diet | The role of diet and nutrient composition in nonalcoholic Fatty liver disease. | 2012 | Details |
| A24596 | 22710480 | Mol Med Rep | Evaluation of Fbxw7 expression and its correlation with expression of SREBP-1 in a mouse model of NAFLD. | 2012 | Details |
| A24598 | 22707395 | Hepatology | Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. | 2012 | Details |
| A24604 | 22700629 | Ann Hepatol |  Correlation of adipose tissue with liver histology in Asian Indian patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24605 | 22700625 | Ann Hepatol |  Gut microbiota and nonalcoholic fatty liver disease. | 2012 | Details |
| A24609 | 22694047 | Clin Transplant | Complications associated with liver transplantation in the obese recipient. | 2012 | Details |
| A24618 | 22686559 | J Proteome Res | Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease. | 2012 | Details |
| A24619 | 22684858 | Hepatology | Nonalcoholic steatohepatitis versus steatosis: adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism. | 2012 | Details |
| A24624 | 22678663 | Cell Mol Life Sci | Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology. | 2012 | Details |
| A24629 | 22673924 | Int J Vitam Nutr Res | Therapeutic effect of metformin and vitamin E versus prescriptive diet in obese adolescents with fatty liver. | 2011 | Details |
| A24633 | 22672485 | J Am Acad Nurse Pract | Nonalcoholic fatty liver disease: the hepatic metabolic syndrome. | 2012 | Details |
| A24634 | 22672330 | Diabet Med | Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management. | 2012 | Details |
| A24645 | 22654421 | World J Gastroenterol | Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2012 | Details |
| A24648 | 22651911 | J Am Soc Hypertens | Effects of increased systemic inflammation and central obesity on arterial stiffness in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24652 | 22648049 | Eur Radiol | Detection of non-alcoholic steatohepatitis in patients with morbid obesity before bariatric surgery: preliminary evaluation with acoustic radiation force impulse imaging. | 2012 | Details |
| A24654 | 22646061 | Intern Med J | Awareness and opinions of non-alcoholic fatty liver disease by hospital specialists. | 2013 | Details |
| A24655 | 25755424 | J Clin Exp Hepatol | Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |