Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25600 | 21665509 | Diabetes Metab | Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus. | 2011 | Details |
| A25602 | 21664213 | Clin Res Hepatol Gastroenterol | Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: mechanisms and pathophysiological role. | 2011 | Details |
| A25603 | 21663607 | Lipids Health Dis | Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans. | 2011 | Details |
| A25607 | 21655948 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2011 | Details |
| A25610 | 21649947 | Ned Tijdschr Geneeskd | [Treatment of non-alcoholic fatty liver disease]. | 2011 | Details |
| A25613 | 21645445 | Zhonghua Gan Zang Bing Za Zhi | [General characteristics and clinical practices of Chinese patients with non-alcoholic fatty liver disease]. | 2011 | Details |
| A25614 | 21645344 | BMC Med | The role of lifestyle changes in the management of chronic liver disease. | 2011 | Details |
| A25617 | 21639814 | Expert Opin Pharmacother | Expert opinion on current therapies for nonalcoholic fatty liver disease. | 2011 | Details |
| A25624 | 21633178 | J Clin Invest | The role of lipid droplets in metabolic disease in rodents and humans. | 2011 | Details |
| A25626 | 21631560 | Aliment Pharmacol Ther | Association between the presence of brown adipose tissue and non-alcoholic fatty liver disease in adult humans. | 2011 | Details |
| A25627 | 21629127 | J Pediatr Gastroenterol Nutr | Mechanisms of lipotoxicity in NAFLD and clinical implications. | 2011 | Details |
| A25631 | 21623852 | Aliment Pharmacol Ther | Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. | 2011 | Details |
| A25633 | 21621638 | Biochim Biophys Acta | Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats. | 2011 | Details |
| A25641 | 21612059 | Vnitr Lek | [Steatosis and steatohepatitis in diabetic patient]. | 2011 | Details |
| A25642 | 21604917 | Ann Med | The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for hepatic steatosis. | 2011 | Details |
| A25647 | 21599535 | Crit Rev Biochem Mol Biol | Insulin signaling to hepatic lipid metabolism in health and disease. | 2011 | Details |
| A25648 | 21598007 | Obes Surg | Clinical predictors of different grades of nonalcoholic fatty liver disease. | 2012 | Details |
| A25650 | 21595271 | Nihon Rinsho | [Attenuation of fatty accumulation in hepatocyte by incretin--expectation of novel medicine for treatment of NASH]. | 2011 | Details |
| A25651 | 21593806 | Obesity (Silver Spring) | Downregulation of hepatic glucose-6-phosphatase-α in patients with hepatic steatosis. | 2011 | Details |
| A25653 | 21587068 | Curr Opin Clin Nutr Metab Care | The 5-lipoxygenase/leukotriene pathway in obesity, insulin resistance, and fatty liver disease. | 2011 | Details |
| A25657 | 21570964 | Exp Mol Pathol | A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A25663 | 21565984 | J Appl Physiol (1985) | Does physical inactivity cause nonalcoholic fatty liver disease? | 2011 | Details |
| A25664 | 21565756 | Orv Hetil | [Clinical correlations of chronic hepatitis C, diabetes mellitus and steatohepatitis]. | 2011 | Details |
| A25665 | 21565479 | Nutr Metab Cardiovasc Dis | Management of metabolic syndrome in children and adolescents. | 2011 | Details |
| A25666 | 21564529 | Am J Transplant | Should metformin be our antiglycemic agent of choice post-transplantation? | 2011 | Details |
| A25671 | 21562784 | Dig Dis Sci | Fatty liver is associated with recurrent bacterial infections independent of metabolic syndrome. | 2011 | Details |
| A25672 | 21562757 | Diabetologia | Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice. | 2011 | Details |
| A25681 | 21556019 | Nat Rev Endocrinol | Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. | 2011 | Details |
| A25682 | 21549692 | Eur J Pharmacol | Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome. | 2011 | Details |
| A25684 | 21547049 | J Ayurveda Integr Med | A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease. | 2010 | Details |
| A25685 | 21546603 | Arterioscler Thromb Vasc Biol | Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation. | 2011 | Details |
| A25686 | 21545576 | Br J Pharmacol | Resistin: functional roles and therapeutic considerations for cardiovascular disease. | 2012 | Details |
| A25687 | 21543214 | J Nutr Biochem | Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver. | 2011 | Details |
| A25688 | 21543212 | J Nutr Biochem | Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes. | 2011 | Details |
| A25691 | 21538280 | Semin Liver Dis | Genetics of alcoholic and nonalcoholic fatty liver disease. | 2011 | Details |
| A25695 | 21534339 | Turk J Pediatr | Abdominal obesity is an independent risk factor for increased carotid intima- media thickness in obese children. | 2011 | Details |
| A25701 | 21521847 | JAMA | Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. | 2011 | Details |
| A25703 | 21521307 | Clin Endocrinol (Oxf) | Correlation of insulin sensitivity with bone mineral status in obese adolescents with nonalcoholic fatty liver disease. | 2011 | Details |
| A25709 | 21519163 | Korean J Gastroenterol | [Association among histopathology, clinical manifestation, and ultrasonographic grades in pediatric non-alcoholic fatty liver disease]. | 2011 | Details |
| A25711 | 21518734 | Arch Dis Child | Lifestyle intervention for non-alcoholic fatty liver disease: prospective cohort study of its efficacy and factors related to improvement. | 2011 | Details |
| A25712 | 21518594 | Chin Med J (Engl) | Association between non-alcoholic fatty liver disease and coronary artery disease severity. | 2011 | Details |
| A25713 | 21517924 | Aliment Pharmacol Ther | Reliability of liver stiffness measurement in non-alcoholic fatty liver disease: the effects of body mass index. | 2011 | Details |
| A25718 | 21510837 | Curr Top Med Chem | A new perspective of cannabinoid 1 receptor antagonists: approaches toward peripheral CB1R blockers without crossing the blood-brain barrier. | 2011 | Details |
| A25720 | 21508207 | J Nutr | Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. | 2011 | Details |
| A25721 | 21507897 | FASEB J | Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts. | 2011 | Details |
| A25727 | 21502673 | Ann Hepatol | Risk factors and predictors of non-alcoholic fatty liver disease in Taiwan. | 2011 | Details |
| A25728 | 21502672 | Ann Hepatol | Non-alcoholic fatty liver disease and the metabolic syndrome in an urban hospital serving an African community. | 2011 | Details |
| A25729 | 21499110 | Eur J Gastroenterol Hepatol | Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity. | 2011 | Details |
| A25730 | 21499089 | Curr Opin Cardiol | Liver function tests and statins. | 2011 | Details |
| A25735 | 21495873 | Toxicol Mech Methods | Epigenetic priming of the metabolic syndrome. | 2011 | Details |
| A25749 | 21484130 | Hepatol Int | Renal function and severity of bright liver. Relationship with insulin resistance, intrarenal resistive index, and glomerular filtration rate. | 2011 | Details |
| A25750 | 21483633 | World J Gastroenterol | Intrahepatic natural killer T cell populations are increased in human hepatic steatosis. | 2011 | Details |
| A25751 | 21480410 | Phytother Res | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. | 2011 | Details |
| A25753 | 21479224 | PLoS One | Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation. | 2011 | Details |
| A25767 | 21476911 | Expert Rev Gastroenterol Hepatol | Autophagy in nonalcoholic steatohepatitis. | 2011 | Details |
| A25772 | 21475632 | Int J Gen Med | The effects of diet-induced obesity on hepatocyte insulin signaling pathways and induction of non-alcoholic liver damage. | 2011 | Details |
| A25780 | 21463618 | Eur J Pharmacol | A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. | 2011 | Details |
| A25786 | 21457446 | Liver Int | Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients. | 2011 | Details |
| A25788 | 21455726 | Diabetologia | Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease. | 2011 | Details |
| A25791 | 21452138 | Ther Umsch | [Non-alcoholic steatohepatitis - from NAFLD to MAFLD]. | 2011 | Details |
| A25797 | 22813407 | Diabetes Metab Syndr | Association of nonalcoholic fatty liver disease with metabolic syndrome in Indian population. | 2012 | Details |
| A25798 | 21449029 | Biotechnol Bioeng | Use of three-dimensional spheroids of hepatocyte-derived reporter cells to study the effects of intracellular fat accumulation and subsequent cytokine exposure. | 2011 | Details |
| A25803 | 21440836 | Biomed Environ Sci | Impacts of types and degree of obesity on non-alcoholic fatty liver disease and related dyslipidemia in Chinese school-age children? | 2011 | Details |
| A25804 | 21440778 | Transplant Proc | De novo fatty liver due to vascular complications after liver transplantation. | 2011 | Details |
| A25805 | 21440669 | Clin Gastroenterol Hepatol | Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008. | 2011 | Details |
| A25808 | 21439567 | Atherosclerosis | Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease. | 2011 | Details |
| A25809 | 21438811 | Expert Rev Cardiovasc Ther | Hepatic steatosis and Type 2 diabetes: current and future treatment considerations. | 2011 | Details |
| A25814 | 21431854 | Curr Diab Rep | Why does NAFLD predict type 2 diabetes? | 2011 | Details |
| A25819 | 21429453 | Arab J Gastroenterol | Incidence and risk factors for non-alcoholic steatohepatitis in females treated with tamoxifen for breast cancer. | 2011 | Details |
| A25821 | 21427524 | J Endocrinol Invest | Risk of cardiovascular disease and chronic kidney disease in diabetic patients with non-alcoholic fatty liver disease: just a coincidence? | 2011 | Details |
| A25825 | 21425426 | Diabetes Metab Res Rev | Non-alcoholic fatty liver disease (NAFLD): why you should care, when you should worry, what you should do. | 2011 | Details |
| A25829 | 21418702 | Ned Tijdschr Geneeskd | [No-invasive determination of liver fat with 1H-MR spectroscopy]. | 2011 | Details |
| A25830 | 21418443 | Haemophilia | The changing face of hepatitis in boys with haemophilia associated with increased prevalence of obesity. | 2011 | Details |
| A25836 | 21412139 | Am J Med Sci | Nonalcoholic fatty liver disease and type 2 diabetes mellitus: the hidden epidemic. | 2011 | Details |
| A25838 | 21410952 | J Inflamm (Lond) | Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice. | 2011 | Details |
| A25852 | 21393105 | Asia Pac J Clin Nutr | Associations between combinations of body mass index plus non-alcoholic fatty liver disease and diabetes mellitus among Korean adults. | 2011 | Details |
| A25853 | 21390143 | World J Gastroenterol | Non-alcoholic fatty liver disease: An early mediator predicting metabolic syndrome in obese children? | 2011 | Details |
| A25854 | 21389796 | Eur J Gastroenterol Hepatol | Noncirrhotic human nonalcoholic fatty liver disease induces portal hypertension in relation to the histological degree of steatosis. | 2010 | Details |
| A25857 | 21386135 | Aging (Albany NY) | Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat. | 2011 | Details |
| A25858 | 21383997 | Acta Biochim Pol | Retinol binding protein-4 as a serum biomarker of intrahepatic lipid content in obese children--preliminary report. | 2011 | Details |
| A25859 | 21382273 | J Biol Regul Homeost Agents | Circulating levels of cytochrome C, gamma-glutamyl transferase, triglycerides and unconjugated bilirubin in overweight/obese patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25861 | 21382165 | Liver Int | A novel and comprehensive mouse model of human non-alcoholic steatohepatitis with the full range of dysmetabolic and histological abnormalities induced by gold thioglucose and a high-fat diet. | 2011 | Details |
| A25866 | 21378565 | Curr Opin Lipidol | Lipidomics is providing new insight into the metabolic syndrome and its sequelae. | 2011 | Details |
| A25870 | 21374659 | Hepatology | Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease. | 2011 | Details |
| A25875 | 21364286 | J Clin Invest | Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2. | 2011 | Details |
| A25876 | 21364120 | Am J Physiol Endocrinol Metab | Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice. | 2011 | Details |
| A25882 | 21356258 | J Hepatol | Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome. | 2011 | Details |
| A25883 | 21355790 | Ann Med | Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environment. | 2011 | Details |
| A25887 | 21352073 | Expert Opin Emerg Drugs | Treatment of non-alcoholic fatty liver disease with focus on emerging drugs. | 2011 | Details |
| A25888 | 21351214 | Inflamm Bowel Dis | Changing shape of disease: nonalcoholic fatty liver disease in Crohn's disease-a case series and review of the literature. | 2011 | Details |
| A25890 | 21350190 | Am J Physiol Gastrointest Liver Physiol | Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model. | 2011 | Details |
| A25891 | 21350183 | Am J Physiol Gastrointest Liver Physiol | Obesity, diabetes mellitus, and liver fibrosis. | 2011 | Details |
| A25892 | 21348922 | Obes Rev | Cardiovascular benefits of bariatric surgery in morbidly obese patients. | 2011 | Details |
| A25894 | 21348181 | G Ital Cardiol (Rome) | [Non-alcoholic fatty liver disease: a new challenge for cardiologists]. | 2010 | Details |
| A25896 | 21346716 | Eur J Clin Nutr | A case-control study on nutritional risk factors in non-alcoholic fatty liver disease in Indian population. | 2011 | Details |
| A25898 | 21345221 | Diabetol Metab Syndr | New clinical score to diagnose nonalcoholic steatohepatitis in obese patients. | 2011 | Details |
| A25900 | 21342625 | Zhongguo Dang Dai Er Ke Za Zhi | [The prevalence of type 2 diabetes mellitus and prediabetes in children]. | 2011 | Details |
| A25903 | 21339799 | PLoS One | Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. | 2011 | Details |
| A25905 | 21339203 | Gut | The role of apolipoprotein A5 in non-alcoholic fatty liver disease. | 2011 | Details |
| A25908 | 21336428 | Nutr Hosp | Effect of two different hypocaloric diets in transaminases and insulin resistance in nonalcoholic fatty liver disease and obese patients. | 2011 | Details |