Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A42975 | 32914727 | Endocr Metab Immune Disord Drug Targets | Berberine as a Potential Multi-Target Agent for Metabolic Diseases: A Review of Investigations for Berberine. | 2021 | Details |
| A42978 | 32899741 | Life (Basel) | Fatty Liver, and Not Visceral Fat, Is More Associated with Liver Fibrosis and Diabetes in Non-Obese Japanese Individuals: A Cross-Sectional Study. | 2020 | Details |
| A42990 | 32882164 | Cell Metab | A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance. | 2020 | Details |
| A42994 | 32869840 | Clin Infect Dis | Fatty Liver Disease in a Prospective North American Cohort of Adults With Human Immunodeficiency Virus and Hepatitis B Virus Coinfection. | 2021 | Details |
| A43003 | 32841331 | J Anim Sci | Increase of E3 ubiquitin ligase NEDD4 expression leads to degradation of its target proteins PTEN/IGF1R during the formation of goose fatty liver. | 2020 | Details |
| A43009 | 32821334 | World J Hepatol | Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling. | 2020 | Details |
| A43014 | 32812927 | Metabol Open | Treatment of nonalcoholic fatty liver disease with dapagliflozin in non-diabetic patients. | 2020 | Details |
| A43021 | 32795106 | Metab Syndr Relat Disord | Metabolic Syndrome in Children and Adolescents: Is There a Universally Accepted Definition? Does it Matter? | 2020 | Details |
| A43032 | 32758101 | J Am Coll Nutr | Interplay Between Insulin Resistance and Body Fat Mass in Evolution of Perturbations Linked to the Metabolic Syndrome in Non-Diabetics: Emphasis on Inflammatory Factors. | 2020 | Details |
| A43035 | 32751062 | Int J Mol Sci | Consumption of Wild Rice (Zizania latifolia) Prevents Metabolic Associated Fatty Liver Disease through the Modulation of the Gut Microbiota in Mice Model. | 2020 | Details |
| A43044 | 32707055 | Metabolism | Making progress in nonalcoholic fatty liver disease (NAFLD) as we are transitioning from the era of NAFLD to dys-metabolism associated fatty liver disease (DAFLD). | 2020 | Details |
| A43045 | 32702498 | Ann Hepatol | Enriched MACK-3 following CHAI and MACK-3 for the noninvasive diagnosis of nonalcoholic steatohepatitis. | 2020 | Details |
| A43047 | 32697967 | EBioMedicine | Thrombospondin1 as a potential therapeutic target for human nonalcoholic fatty liver disease. | 2020 | Details |
| A43053 | 32693115 | J Ethnopharmacol | A review of the processed Polygonum multiflorum (Thunb.) for hepatoprotection: Clinical use, pharmacology and toxicology. | 2020 | Details |
| A43063 | 32652034 | J Nutr | A Low ω-6 to ω-3 PUFA Ratio (n-6:n-3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth. | 2020 | Details |
| A43066 | 32646248 | Expert Opin Drug Discov | What is on the horizon for type 2 diabetes pharmacotherapy? - An overview of the antidiabetic drug development pipeline. | 2020 | Details |
| A43087 | 32598598 | Ter Arkh | [Diabetes mellitus and chronic liver diseases. Literature review (part 2): treatment features]. | 2019 | Details |
| A43094 | 32586106 | Antioxid Redox Signal | Phospholipase D as a Potential Modulator of Metabolic Syndrome: Impact of Functional Foods. | 2020 | Details |
| A43095 | 32585124 | Appl Physiol Nutr Metab | Lipid droplets are both highly oxidized and Plin2-covered in hepatocytes of diet-induced obese mice. | 2020 | Details |
| A43098 | 32571750 | Clin Res Hepatol Gastroenterol | Cytochrome P450 2E1 should not be neglected for acetaminophen-induced liver injury in metabolic diseases with altered insulin levels or glucose homeostasis. | 2020 | Details |
| A43108 | 32549999 | Clin Hypertens | Uric acid and cardiometabolic diseases. | 2020 | Details |
| A43131 | 32482717 | J Lipid Res | Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings. | 2020 | Details |
| A43132 | 32479251 | Endocr Metab Immune Disord Drug Targets | Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men. | 2021 | Details |
| A43141 | 32443199 | Environ Pollut | Lipidomics insight into chronic exposure to ambient air pollution in mice. | 2020 | Details |
| A43160 | 32403898 | Clin Exp Pediatr | Early menarche and its consequence in Korean female: reducing fructose intake could be one solution. | 2020 | Details |
| A43173 | 32374328 | Biomater Sci | A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection. | 2020 | Details |
| A43192 | 32338040 | Antioxid Redox Signal | Glycomacropeptide: A Bioactive Milk Derivative to Alleviate Metabolic Syndrome Outcomes. | 2020 | Details |
| A43201 | 32316687 | Nutrients | Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation. | 2020 | Details |
| A43246 | 32184272 | Diabetes | Branched-Chain Amino Acids Exacerbate Obesity-Related Hepatic Glucose and Lipid Metabolic Disorders via Attenuating Akt2 Signaling. | 2020 | Details |
| A43248 | 32181687 | DNA Cell Biol | DES1: A Key Driver of Lipotoxicity in Metabolic Disease. | 2020 | Details |
| A43257 | 32140409 | IDCases | Invasive pulmonary aspergillosis in a patient with cirrhosis. | 2020 | Details |
| A43262 | 32122723 | J Hepatol | β-arrestin: Dr Jekyll and Mr Hyde in NASH and fibrosis. | 2020 | Details |
| A43268 | 32109931 | Eur J Gastroenterol Hepatol | Homeostasis model assessment of insulin resistance and lobular inflammation in nondiabetic patients with nonalcoholic fatty liver disease: methodological considerations. | 2020 | Details |
| A43313 | 32006524 | Transl Res | Role of placental fibrinogen-like protein 1 in gestational diabetes. | 2020 | Details |
| A43330 | 31979841 | J Assoc Physicians India | Insulin Resistance, Dyslipidaemia and Glycemic Abnormalities in Nondiabetic NAFLD (Non Alcoholic Fatty Liver Disease). | 2020 | Details |
| A43331 | 31979839 | J Assoc Physicians India | Study of Correlation between Carotid Intimalthickness and Insulin Resistance in Patients with NAFLD. | 2020 | Details |
| A43348 | 31930974 | Metabolism | Obeticholic acid for the treatment of nonalcoholic steatohepatitis: Expectations and concerns. | 2020 | Details |
| A43359 | 31910158 | Endocr Connect | Lipid accumulation product independently correlate with hepatic steatosis quantified by controlled attenuation parameter in women with polycystic ovary syndrome. | 2020 | Details |
| A43363 | 31903735 | Obesity (Silver Spring) | Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders. | 2020 | Details |
| A43369 | 31899812 | Hepatology | Ceramides: A Cause of Insulin Resistance in Nonalcoholic Fatty Liver Disease in Both Murine Models and Humans. | 2020 | Details |
| A43380 | 31871510 | Curr Ther Res Clin Exp | Hepatoprotective Effects of a Ruthenium(II) Schiff Base Complex in Rats with Diet-Induced Prediabetes. | 2019 | Details |
| A43395 | 31845444 | Phytother Res | Bitter melon fruit extract has a hypoglycemic effect and reduces hepatic lipid accumulation in ob/ob mice. | 2019 | Details |
| A43399 | 31834843 | J Med Food | Natural Products: New Hope for Nonalcoholic Steatohepatitis? | 2019 | Details |
| A43425 | 31754898 | Curr Diab Rep | Hyperglycemia During Pregnancy and Long-Term Offspring Outcomes. | 2019 | Details |
| A43432 | 31728756 | Endocrine | Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis. | 2019 | Details |
| A43448 | 31693811 | N Engl J Med | Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides. | 2019 | Details |
| A43450 | 31680281 | Hepatology | Liver Fat and Cardiometabolic Risk Factors Among School-Age Children. | 2020 | Details |
| A43460 | 31663469 | Curr Med Chem | Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids. | 2021 | Details |
| A43468 | 31649547 | Front Pharmacol | Mitophagy in Hepatic Insulin Resistance: Therapeutic Potential and Concerns. | 2019 | Details |
| A43475 | 31613385 | Hepatology | Reply. | 2020 | Details |
| A43478 | 31610029 | Hepatology | Letter to the Editor: Intrahepatic Lipid Content After Insulin Glargine Addition to Metformin in Type II Diabetes Mellitus With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A43486 | 31592705 | Metab Syndr Relat Disord | Triglycerides as a Metabolic Target in Afrocaribbean Infertile Women with Polycystic Ovary Syndrome. | 2019 | Details |
| A43492 | 31587376 | Biofactors | Discovery of a role of the novel hepatokine, hepassocin, in obesity. | 2019 | Details |
| A43496 | 31584530 | J Cardiovasc Pharmacol | NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium. | 2019 | Details |
| A43497 | 31582899 | Mediators Inflamm | Pattern Recognition Receptor-Mediated Chronic Inflammation in the Development and Progression of Obesity-Related Metabolic Diseases. | 2019 | Details |
| A43503 | 31573550 | J Clin Invest | The gut microbiome and metabolic syndrome. | 2019 | Details |
| A43504 | 31570275 | J Hepatol | Endoscopic bariatric and metabolic therapies for non-alcoholic fatty liver disease. | 2019 | Details |
| A43508 | 31559328 | GE Port J Gastroenterol | Mauriac Syndrome: A Rare Hepatic Glycogenosis in Poorly Controlled Type 1 Diabetes. | 2019 | Details |
| A43556 | 31419758 | Cytokine | The association of angiopoietin-like peptide 4 levels with obesity and hepatosteatosis in adolescents. | 2019 | Details |
| A43602 | 31311004 | J Endocrinol | Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS. | 2019 | Details |
| A43604 | 31301829 | J Dairy Sci | Invited review: Sphingolipid biology in the dairy cow: The emerging role of ceramide. | 2019 | Details |
| A43605 | 31301336 | Metabolism | Effects of sodium-glucose co-transporter-2 (SGLT2) inhibitors on non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Ex quo et quo vadimus? | 2019 | Details |
| A43607 | 31300671 | Sci Rep | Insulin resistance and metabonomics analysis of fatty liver haemorrhagic syndrome in laying hens induced by a high-energy low-protein diet. | 2019 | Details |
| A43627 | 31258478 | Front Pharmacol | Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review. | 2019 | Details |
| A43639 | 31237448 | Am J Physiol Endocrinol Metab | Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes. | 2019 | Details |
| A43643 | 31227258 | J Hepatol | Hepatic fat: Pathogenic trigger or passenger? | 2019 | Details |
| A43644 | 31225877 | J Clin Endocrinol Metab | Letter to the Editor: "Hepatic Insulin Extraction in NAFLD Is Related to Insulin Resistance Rather Than Liver Fat Content". | 2019 | Details |
| A43645 | 31225873 | J Clin Endocrinol Metab | Response to Letter to the Editor: "Hepatic Insulin Extraction in NAFLD Is Related to Insulin Resistance Rather Than Liver Fat Content". | 2019 | Details |
| A43647 | 31220350 | Hepatology | Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε. | 2019 | Details |
| A43650 | 31200402 | Klin Lab Diagn | [Insulin resistance is an alimentary deficiency of energy substrates (glucose) in the biological reaction of exotrophy and aphysiology compensation by fatty acids via the biological reaction of endothrophy.] | 2019 | Details |
| A43657 | 31168510 | Hepatol Commun | Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis. | 2019 | Details |
| A43658 | 31167890 | Diabetes Care | Fatty Liver Among Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study). | 2019 | Details |
| A43671 | 31142011 | Int J Mol Sci | Involvement of G-Protein-Coupled Receptor 40 in the Inhibitory Effects of Docosahexaenoic Acid on SREBP1-Mediated Lipogenic Enzyme Expression in Primary Hepatocytes. | 2019 | Details |
| A43678 | 31121179 | Metabolism | Helicobacter pylori infection and nonalcoholic fatty liver disease: Are the four meta-analyses favoring an intriguing association pointing to the right direction? | 2019 | Details |
| A43683 | 31106419 | J Cell Physiol | Impact of different ectopic fat depots on cardiovascular and metabolic diseases. | 2019 | Details |
| A43708 | 31062325 | Adv Exp Med Biol | The Full Spectrum of Alzheimer's Disease Is Rooted in Metabolic Derangements That Drive Type 3 Diabetes. | 2019 | Details |
| A43716 | 31048404 | J Lipid Res | Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption. | 2019 | Details |
| A43719 | 31030166 | J Nutr Biochem | High-fructose drinks affect microRNAs expression differently in lean and obese mice. | 2019 | Details |
| A43728 | 31012550 | Klin Lab Diagn | [Ozone oxidizes oleic fatty acid with the highest rate constant and does not oxidize palmitic acid. Different physicochemical parameters of substrates and their role in phylogenesis.] | 2019 | Details |
| A43731 | 31006135 | Hepatology | Incretin-Based Therapies for the Management of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes. | 2019 | Details |
| A43755 | 30950170 | Helicobacter | Helicobacter pylori infection and nonalcoholic fatty liver disease: Time for large clinical trials evaluating eradication therapy. | 2019 | Details |
| A43762 | 30945509 | Zhen Ci Yan Jiu | [Progress of researches on mechanisms of acupuncture therapy for insulin resistance]. | 2019 | Details |
| A43783 | 30890204 | Gene Expr | Sterol 12α-Hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP-1C Pathway via FGF21 and FGF15. | 2019 | Details |
| A43824 | 30785686 | Klin Lab Diagn | [Formation in the phylogenesis of three pulls of cells with expressed different absorption and metabolism of fatty acids. Insulin and medium chains fatty acids.] | 2019 | Details |
| A43827 | 30770439 | Proc Natl Acad Sci U S A | PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin. | 2019 | Details |
| A43834 | 30763014 | J Ultrason | Multifocal fatty liver disease, insulin resistance and carotid atherosclerosis: exploring the interrelated relationship. | 2018 | Details |
| A43843 | 30721959 | Adv Nutr | Mechanisms of Action of Probiotics. | 2019 | Details |
| A43845 | 30706731 | Diab Vasc Dis Res | Pioglitazone: The forgotten, cost-effective cardioprotective drug for type 2 diabetes. | 2019 | Details |
| A43857 | 30670473 | J Lipid Res | Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice. | 2019 | Details |
| A43858 | 30670274 | Complement Ther Med | Effect of Zataria multiflora on fatty liver disease. | 2018 | Details |
| A43859 | 30670253 | Complement Ther Med | Effect of Zataria multiflora on fatty liver disease. | 2018 | Details |
| A43866 | 30654277 | J Nutr Biochem | A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs. | 2018 | Details |
| A43869 | 30648577 | J Food Drug Anal | Identification of baicalin from Bofutsushosan and Daisaikoto as a potent inducer of glucose uptake and modulator of insulin signaling-associated pathways. | 2018 | Details |
| A43873 | 30629464 | FASEB J | Maternal prebiotic supplementation reduces fatty liver development in offspring through altered microbial and metabolomic profiles in rats. | 2019 | Details |
| A43875 | 30617219 | Diabetes | Perilipin 5 Deletion in Hepatocytes Remodels Lipid Metabolism and Causes Hepatic Insulin Resistance in Mice. | 2019 | Details |
| A43884 | 30576689 | Metabolism | Ectopic lipid deposition mediates insulin resistance in adipose specific 11β-hydroxysteroid dehydrogenase type 1 transgenic mice. | 2018 | Details |
| A43896 | 30541093 | Am J Clin Nutr | A 12-wk whole-grain wheat intervention protects against hepatic fat: the Graandioos study, a randomized trial in overweight subjects. | 2018 | Details |
| A43899 | 30503805 | Metabolism | Research developments in metabolism 2018. | 2018 | Details |
| A43939 | 30403316 | J Intern Med | Precision medicine in type 2 diabetes. | 2018 | Details |
| A43957 | 30325692 | Metab Syndr Relat Disord | Determinants of Fasting Hyperglucagonemia in Patients with Type 2 Diabetes and Nondiabetic Control Subjects. | 2018 | Details |